GB1242211A - Pharmaceutical composition - Google Patents
Pharmaceutical compositionInfo
- Publication number
- GB1242211A GB1242211A GB36270/67A GB3627067A GB1242211A GB 1242211 A GB1242211 A GB 1242211A GB 36270/67 A GB36270/67 A GB 36270/67A GB 3627067 A GB3627067 A GB 3627067A GB 1242211 A GB1242211 A GB 1242211A
- Authority
- GB
- United Kingdom
- Prior art keywords
- medicament
- particle size
- carrier
- powder
- effective particle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Abstract
1,242,211. Powder compositions for inhalation. FISONS PHARMACEUTICALS Ltd. 23 July, 1968 [8 Aug., 1967], No. 36270/67. Heading A5B. A pharmaceutical powder composition for inhalation comprises a mixture of a solid finely divided medicament having an effective particle size in the range 0.01 to 10 microns and a solid pharmaceutically acceptable water-soluble carrier having an effective particle size in the range 30-80 microns. The composition is preferably substantially free of particles having effective particle sizes in the range 11-29 microns. The medicament may be diluted with a solid pharmaceutically acceptable watersoluble diluent of the same effective particle size. The diluent or carrier may be dextran, mannitol or lactose preferably crystalline lactose. The medicament may be an antianaphylactic agent such as sodium chromoglycate, a sympathomimetic amine such as isoprenaline or ephedrine, an antibiotic such as penicillin or tetracycline, a steroid, enzyme, vitamin, antihistamine or mucolytic such as N- acetyl cysteine. A preferred composition contains sodium chromoglycate and isoprenaline sulphate. The surface characteristics of the medicament or carrier particles may have been modified by crystallisations, spray drying, precipitation or by coating with a pharmaceutically acceptable material, e.g. stearic acid or polyvinyl pyrrolidone (which coating may give the medicament sustained release action). The powder may be contained in a capsule, e.g. of gelatin or plastic, which is pierced for administration. The powder may be administered as a dispersion in an air stream obtained by simultaneous rotation and vibration of the pierced capsule. The composiitons are prepared by mixing together, preferably in a stirred mixer, the medicament and carrier, which if necessary have been subjected to comminution and particle size classification prior to mixing.
Priority Applications (20)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB36270/67A GB1242211A (en) | 1967-08-08 | 1967-08-08 | Pharmaceutical composition |
IE163/73A IE32872B1 (en) | 1967-08-08 | 1968-07-25 | Drug for use in pharmaceutical composition |
IE898/68A IE32343B1 (en) | 1967-08-08 | 1968-07-25 | Pharmaceutical composition |
FI682158A FI48973C (en) | 1967-08-08 | 1968-07-30 | A method of making a readily fluidizable inhalant. |
US748937A US3634582A (en) | 1967-08-08 | 1968-07-31 | Pharmaceutical compositions |
BE718846D BE718846A (en) | 1967-08-08 | 1968-07-31 | |
CA026,437A CA946280A (en) | 1967-08-08 | 1968-08-01 | Inhalant powder compositions |
NL6811060.A NL161984C (en) | 1967-08-08 | 1968-08-02 | METHOD FOR PREPARING A PHARMACEUTICAL POWDER-INHALED PREPARATION, AND CONTAINER CONTAINING SUCH A PREPARATION |
DE19681792799 DE1792799A1 (en) | 1967-08-08 | 1968-08-03 | PHARMACEUTICAL PREPARATIONS |
DE1792207A DE1792207C3 (en) | 1967-08-08 | 1968-08-03 | Powder preparation for inhalation |
NO03102/68A NO128307B (en) | 1967-08-08 | 1968-08-07 | |
SE6810634A SE372420B (en) | 1967-08-08 | 1968-08-07 | |
DK380968AA DK123276B (en) | 1967-08-08 | 1968-08-07 | Process for the preparation of an easily fluidizable inhalant. |
FR162134A FR8142M (en) | 1967-08-08 | 1968-08-07 | |
FR163601A FR1605538A (en) | 1967-08-08 | 1968-08-21 | |
JP2321371A JPS5643448B1 (en) | 1967-08-08 | 1971-04-14 | |
US158059A US3860618A (en) | 1967-08-08 | 1971-06-29 | Chromone |
US05/401,251 US3957965A (en) | 1967-08-08 | 1973-09-27 | Sodium chromoglycate inhalation medicament |
MY330/74A MY7400330A (en) | 1967-08-08 | 1974-12-30 | Pharmaceutical composition |
MY329/74A MY7400329A (en) | 1967-08-08 | 1974-12-30 | Drug for use in pharmaceutical composition |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB36270/67A GB1242211A (en) | 1967-08-08 | 1967-08-08 | Pharmaceutical composition |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1242211A true GB1242211A (en) | 1971-08-11 |
Family
ID=10386572
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB36270/67A Expired GB1242211A (en) | 1967-08-08 | 1967-08-08 | Pharmaceutical composition |
Country Status (14)
Country | Link |
---|---|
US (1) | US3634582A (en) |
JP (1) | JPS5643448B1 (en) |
BE (1) | BE718846A (en) |
CA (1) | CA946280A (en) |
DE (2) | DE1792207C3 (en) |
DK (1) | DK123276B (en) |
FI (1) | FI48973C (en) |
FR (2) | FR8142M (en) |
GB (1) | GB1242211A (en) |
IE (1) | IE32343B1 (en) |
MY (2) | MY7400329A (en) |
NL (1) | NL161984C (en) |
NO (1) | NO128307B (en) |
SE (1) | SE372420B (en) |
Cited By (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2229981A1 (en) * | 1971-06-22 | 1972-12-28 | Fisons Ltd , London | Pharmaceutical powder preparations |
FR2481601A1 (en) * | 1980-04-30 | 1981-11-06 | Fisons Ltd | PHARMACEUTICAL MIXTURE OF 1,3-BIS- (2-CARBOXYCHROMONE-5-YL-OXY) -PROPANE-2-OL, OR ONE OF ITS SALTS, AND AT LEAST ONE BRONCHODILATOR |
US4515805A (en) * | 1980-11-05 | 1985-05-07 | Fisons Plc | Soluble sodium cromoglycate compositions |
US5551489A (en) * | 1993-10-01 | 1996-09-03 | Astra Aktiebolag | Agglomeration of finely divided powders |
US6102036A (en) * | 1994-04-12 | 2000-08-15 | Smoke-Stop | Breath activated inhaler |
US6153224A (en) * | 1995-01-31 | 2000-11-28 | Co-Ordinated Drug Development Limited | Carrier particles for use in dry powder inhalers |
US6183782B1 (en) | 1994-03-15 | 2001-02-06 | Glaxo Group Limited | Inhalation composition containing lactose pellets |
US6221338B1 (en) | 1993-10-26 | 2001-04-24 | Vectura Limited | Method of producing particles for use in dry powder inhalers |
US6371171B1 (en) | 1993-10-01 | 2002-04-16 | Astra Aktiebolag | Agglomeration of finely divided powders |
US6436902B1 (en) | 1994-12-22 | 2002-08-20 | Astrazeneca Ab | Therapeutic preparations for inhalation |
US6524557B1 (en) | 1994-12-22 | 2003-02-25 | Astrazeneca Ab | Aerosol formulations of peptides and proteins |
US6610653B1 (en) | 1994-06-23 | 2003-08-26 | Astrazeneca Ab | Therapeutic preparation for inhalation |
US6632456B1 (en) | 1993-06-24 | 2003-10-14 | Astrazeneca Ab | Compositions for inhalation |
US6794357B1 (en) | 1993-06-24 | 2004-09-21 | Astrazeneca Ab | Compositions for inhalation |
US6846801B1 (en) | 1993-06-24 | 2005-01-25 | Astrazeneca Ab | Systemic administration of a therapeutic preparation |
US6884794B2 (en) | 2000-04-17 | 2005-04-26 | Chiesi Farmaceutici S.P.A. | Pharmaceutical formulations for dry powder inhalers in the form of hard-pellets |
US7399528B2 (en) | 1999-07-16 | 2008-07-15 | Chiesi Farmaceutici S.P.A. | Powder particles with smooth surface for use in inhalation therapy |
US7541022B2 (en) | 2000-04-17 | 2009-06-02 | Vectura Limited | Pharmaceutical formulations for dry powder inhalers |
US7763280B2 (en) | 2002-11-28 | 2010-07-27 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Tiotropium containing powder formulation for inhalation |
US8205614B2 (en) | 1999-09-04 | 2012-06-26 | Innovata Biomed Limited | Delivery device |
US8236979B2 (en) | 2008-07-24 | 2012-08-07 | American Air Liquide, Inc. | Methods for synthesis of heteroleptic cyclopentadienyl transition metal precursors |
WO2013104892A1 (en) | 2012-01-13 | 2013-07-18 | Hovione Inter Limited | Application of high dose compounds via inhalation |
US8511302B2 (en) | 2004-04-24 | 2013-08-20 | Innovata Biomed Limited | Dose counter mechanisms for medicament delivery devices |
US8800550B2 (en) | 2001-11-23 | 2014-08-12 | Innovata Biomed Limited | Medicament delivery assembly |
US8851069B2 (en) | 2004-04-21 | 2014-10-07 | Innovata Biomed Limited | Inhaler |
US9987229B2 (en) | 2003-09-02 | 2018-06-05 | Norton Healthcare Ltd. | Process for preparing a medicament |
WO2020031119A1 (en) | 2018-08-07 | 2020-02-13 | Norton (Waterford) Limited | Application of raman spectroscopy for the manufacture of inhalation powders |
US11090294B2 (en) | 2009-12-01 | 2021-08-17 | Glaxo Group Limited | Combinations of a muscarinic receptor antagonist and a beta-2 adrenoreceptor agonist |
US11116721B2 (en) | 2009-02-26 | 2021-09-14 | Glaxo Group Limited | Pharmaceutical formulations comprising 4-{(1R)-2-[(6-{2-[(2,6-dichlorobenzyl)oxy]ethoxy}hexyl)amino]-1-hydroxyethyl}-2-(hydroxymethyl) phenol |
EP4316473A2 (en) | 2013-03-28 | 2024-02-07 | Vectura Limited | Use of stearate in an inhalable formulation |
Families Citing this family (60)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE787100A (en) * | 1971-08-06 | 1973-02-02 | Beecham Group Ltd | COMPOSITION FOR THE TREATMENT OF ASTHMA |
GB1410588A (en) * | 1971-08-10 | 1975-10-22 | Fisons Ltd | Composition |
DE2332663C2 (en) * | 1973-06-23 | 1986-07-31 | Schering AG, 1000 Berlin und 4709 Bergkamen | Use of corticosteroid active ingredients for inhalation therapy |
DE2535258C2 (en) * | 1974-08-10 | 1993-06-03 | Fisons Plc, Ipswich, Suffolk | Inhalable drug in pellet form |
US4161516A (en) * | 1975-07-25 | 1979-07-17 | Fisons Limited | Composition for treating airway disease |
FI770215A (en) * | 1976-01-30 | 1977-07-31 | Fisons Ltd | |
JPS59163313A (en) * | 1983-03-09 | 1984-09-14 | Teijin Ltd | Peptide hormone composition for nasal administration |
JP2770970B2 (en) * | 1987-04-09 | 1998-07-02 | フアイソンズ・ピーエルシー | Pharmaceutical composition containing pentamidine |
US5204113A (en) * | 1987-04-09 | 1993-04-20 | Fisons Plc | Pharmaceutical compositions containing pentamidine |
DE4140689B4 (en) * | 1991-12-10 | 2007-11-22 | Boehringer Ingelheim Kg | Inhalable powders and process for their preparation |
WO1993025193A1 (en) * | 1992-06-12 | 1993-12-23 | Teijin Limited | Pharmaceutical preparation for intra-airway administration |
NL9301851A (en) * | 1993-10-26 | 1995-05-16 | Cordis Europ | Cryo-ablation catheter. |
DE4425255A1 (en) * | 1994-07-16 | 1996-01-18 | Asta Medica Ag | Formulation for inhalation application |
KR100467058B1 (en) * | 1997-05-27 | 2005-01-24 | 디렉트-할러 아/에스 | Inhaler for powdered medicaments |
US7354894B2 (en) * | 1998-08-18 | 2008-04-08 | The Regents Of The University Of California | Preventing airway mucus production by administration of EGF-R antagonists |
CZ2001584A3 (en) * | 1998-08-18 | 2002-06-12 | The Regents Of The University Of California | Prevention of phlegm formation in air passages by administering EGF-R antagonists |
EP1129705A1 (en) * | 2000-02-17 | 2001-09-05 | Rijksuniversiteit te Groningen | Powder formulation for inhalation |
BR0107304A (en) * | 2000-10-12 | 2002-08-13 | Boehringer Ingelheim Pharma | Inhalation powder containing tiotropium |
UA75375C2 (en) | 2000-10-12 | 2006-04-17 | Boehringer Ingelheim Pharma | Method for producing powdery preparations for inhaling |
US20060194773A1 (en) * | 2001-07-13 | 2006-08-31 | Paratek Pharmaceuticals, Inc. | Tetracyline compounds having target therapeutic activities |
DE10141377A1 (en) | 2001-08-23 | 2003-03-13 | Boehringer Ingelheim Pharma | Scattering process for the production of powder formulations |
EP1487417A4 (en) * | 2001-09-17 | 2010-03-17 | Glaxo Group Ltd | Dry powder medicament formulations |
MXPA04004730A (en) * | 2001-11-19 | 2004-07-30 | Becton Dickinson Co | Pharmaceutical compositions in particulate form. |
US6900317B2 (en) | 2002-02-19 | 2005-05-31 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Salts of the CGRP antagonist BIBN4096 and inhalable powdered medicaments containing them |
DE10207026A1 (en) * | 2002-02-20 | 2003-08-28 | Boehringer Ingelheim Kg | Stable inhalable powder of the calcitonin gene-related peptide antagonist, BIBN4096, useful for treating migraine, in the form of spherical nano-structured particles obtained by spray-drying |
US20040014679A1 (en) * | 2002-02-20 | 2004-01-22 | Boehringer Ingelheim Pharma Gmbh & Co., Kg | Inhalation powder containing the CGRP antagonist BIBN4096 and process for the preparation thereof |
JP2006516531A (en) * | 2002-08-21 | 2006-07-06 | ノートン ヘルスケアー リミテッド | Inhalation composition |
DE10255387A1 (en) * | 2002-11-28 | 2004-06-09 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | New tiotropium-containing powder formulation for inhalation |
DE10317461A1 (en) | 2003-04-16 | 2004-10-28 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Preparing microparticles labeled with technetium, useful as powders for inhalation, e.g. to study deposition of pharmaceuticals, such as anticholinergic agents, involves incubation with solution of technetium salt |
US20050042179A1 (en) * | 2003-08-18 | 2005-02-24 | Boehringer Ingelheim International Gmbh | Inhalative powder formulations containing the CGRP-antagonist 1-[N2-[3,5-dibromo-N-[[4-(3,4-dihydro-2(1H)-oxoquinazolin-3-yl)-1-piperidinyl]carbonyl]-D-tyrosyl]-L-lysyl]-4-(4-pyridinyl)-piperazine |
DE10338402A1 (en) * | 2003-08-18 | 2005-03-17 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Spray-dried, amorphous BIBN 4096, process for its preparation and its use as inhalant |
US20050043247A1 (en) * | 2003-08-18 | 2005-02-24 | Boehringer Ingelheim International Gmbh | Spray-dried amorphous BIBN 4096, process for preparing and the use thereof as inhalative |
DE10338403A1 (en) * | 2003-08-18 | 2005-03-17 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Powder formulation containing the CGRP antagonist 1- [N 2 - [3,5-dibromo-N - [[4- (3,4-dihydro-2 (1 H) -oxoquinazolin-3-yl] -1-piperidinyl] carbonyl] -D-tyrosyl] -L-lysyl] -4- (4-pyrindinyl) piperazine, process for its preparation and its use as inhalant |
DE10338399A1 (en) * | 2003-08-18 | 2005-03-17 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Microparticles containing the CGRP antagonist 1- [N 2 - [3,5-dibromo-N - [[4- (3,4-dihydro-2 (1H) -oxoquinazolin-3-yl) -1-piperidinyl] carbonyl] -D-tyrosyl] -L-lysyl] -4- (4-pyridinyl) -piperazine, process for their preparation and their use as inhalation powder |
DE10338407A1 (en) * | 2003-08-18 | 2005-03-17 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | New inhalable powders containing the CGRP antagonist 1- [N 2 - [3,5-dibromo-N - [[4- (3,4-dihydro-2 (1H) -oxoquinazolin-3-yl) -1-piperidinyl] carbonyl] -D-tyrosyl] -L-lysyl] -4- (4-pyridinyl) -piperazine |
US20050042178A1 (en) * | 2003-08-18 | 2005-02-24 | Boehringer Ingelheim International Gmbh | Microparticles containing the CGRP-antagonist 1-[N2-[3,5-dibrom-N-[[4-(3,4-dihydro-2(1H)-oxoquinazoline-3-yl)-1-piperidinyl]carbonyl]-D-tyrosyl]-L-lysyl]-4-(4-pyridinyl)-piperazine, process for preparing and the use thereof as inhalation powder |
PE20050489A1 (en) | 2003-11-04 | 2005-09-02 | Glaxo Group Ltd | ANTAGONISTS OF MUSCARINE ACETYLCHOLINE RECEPTORS |
TWI363759B (en) | 2004-04-27 | 2012-05-11 | Glaxo Group Ltd | Muscarinic acetylcholine receptor antagonists |
US7723306B2 (en) * | 2004-05-10 | 2010-05-25 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Spray-dried powder comprising at least one 1,4 O-linked saccharose-derivative and methods for their preparation |
US7611709B2 (en) * | 2004-05-10 | 2009-11-03 | Boehringer Ingelheim Pharma Gmbh And Co. Kg | 1,4 O-linked saccharose derivatives for stabilization of antibodies or antibody derivatives |
US7727962B2 (en) * | 2004-05-10 | 2010-06-01 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Powder comprising new compositions of oligosaccharides and methods for their preparation |
DE102004048389A1 (en) * | 2004-10-01 | 2006-04-06 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Modification of surfaces of lactose as adjuvant for use with powder inhalants |
DE102004048390A1 (en) * | 2004-10-01 | 2006-04-06 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | New powder inhalants based on modified lactose mixtures as adjuvant |
EP1848444B1 (en) * | 2005-02-10 | 2016-11-09 | Glaxo Group Limited | Processes for making lactose utilizing pre-classification techniques and pharmaceutical formulations formed therefrom |
US9925282B2 (en) | 2009-01-29 | 2018-03-27 | The General Hospital Corporation | Cromolyn derivatives and related methods of imaging and treatment |
WO2014007773A1 (en) * | 2012-07-05 | 2014-01-09 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | Compositions comprising muscarinic receptor antagonist and sorbitol |
WO2014007772A2 (en) | 2012-07-05 | 2014-01-09 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | Inhalation compositions comprising glucose anhydrous |
WO2014007771A2 (en) | 2012-07-05 | 2014-01-09 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | Inhalation compositions comprising muscarinic receptor antagonist |
US20150174064A1 (en) * | 2012-07-05 | 2015-06-25 | Arven IIac Sanayi Ve Ticaret A.S. | Compositions comprising muscarinic receptor antagonist and glucose anhydrous |
US9855276B2 (en) | 2012-10-25 | 2018-01-02 | The General Hospital Corporation | Combination therapies for the treatment of Alzheimer's disease and related disorders |
US10525005B2 (en) | 2013-05-23 | 2020-01-07 | The General Hospital Corporation | Cromolyn compositions and methods thereof |
EP3054948B1 (en) | 2013-10-08 | 2020-08-12 | AI Therapeutics, Inc. | Rapamycin for the treatment of lymphangioleiomyomatosis |
CN110305095A (en) * | 2013-10-22 | 2019-10-08 | 综合医院公司 | Cromoglycic acid derivative and the correlation technique of imaging and treatment |
PL3125875T3 (en) | 2014-04-04 | 2023-11-20 | AI Therapeutics, Inc. | An inhalable rapamycin formulation for treating age-related conditions |
JP6679584B2 (en) | 2014-10-07 | 2020-04-15 | エイアイ・セラピューティクス・インコーポレーテッド | Inhalable rapamycin formulations for treating pulmonary hypertension |
AU2017321782B2 (en) | 2016-08-31 | 2022-03-10 | The General Hospital Corporation | Macrophages/microglia in neuro-inflammation associated with neurodegenerative diseases |
MX2019014671A (en) * | 2017-06-28 | 2020-02-07 | Philip Morris Products Sa | Container with particles for use with inhaler. |
MX2020000577A (en) | 2017-07-20 | 2020-09-10 | Aztherapies Inc | Powdered formulations of cromolyn sodium and ibuprofen. |
EP3817739A4 (en) | 2018-07-02 | 2022-04-13 | The General Hospital Corporation | Powdered formulations of cromolyn sodium and ?-lactose |
US20230310363A1 (en) | 2020-08-28 | 2023-10-05 | Universität Linz | Use of leoligin in the prevention of tissue damage |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1792207U (en) | 1959-04-14 | 1959-07-16 | Esslinger Sack Und Planenfabri | TRANSPORTABLE GARDEN SWIMMING POOL OR POOL WITH WALLS MADE OF PLASTIC FOIL. |
FR1489749A (en) * | 1965-03-25 | 1967-07-28 | Fisons Pharmaceuticals Ltd | Process for the preparation of bis-chromonyl compounds and their derivatives |
-
1967
- 1967-08-08 GB GB36270/67A patent/GB1242211A/en not_active Expired
-
1968
- 1968-07-25 IE IE898/68A patent/IE32343B1/en unknown
- 1968-07-30 FI FI682158A patent/FI48973C/en active
- 1968-07-31 US US748937A patent/US3634582A/en not_active Expired - Lifetime
- 1968-07-31 BE BE718846D patent/BE718846A/xx not_active IP Right Cessation
- 1968-08-01 CA CA026,437A patent/CA946280A/en not_active Expired
- 1968-08-02 NL NL6811060.A patent/NL161984C/en not_active IP Right Cessation
- 1968-08-03 DE DE1792207A patent/DE1792207C3/en not_active Expired
- 1968-08-03 DE DE19681792799 patent/DE1792799A1/en not_active Ceased
- 1968-08-07 NO NO03102/68A patent/NO128307B/no unknown
- 1968-08-07 FR FR162134A patent/FR8142M/fr not_active Expired
- 1968-08-07 DK DK380968AA patent/DK123276B/en unknown
- 1968-08-07 SE SE6810634A patent/SE372420B/xx unknown
- 1968-08-21 FR FR163601A patent/FR1605538A/fr not_active Expired
-
1971
- 1971-04-14 JP JP2321371A patent/JPS5643448B1/ja active Pending
-
1974
- 1974-12-30 MY MY329/74A patent/MY7400329A/en unknown
- 1974-12-30 MY MY330/74A patent/MY7400330A/en unknown
Cited By (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2229981A1 (en) * | 1971-06-22 | 1972-12-28 | Fisons Ltd , London | Pharmaceutical powder preparations |
FR2481601A1 (en) * | 1980-04-30 | 1981-11-06 | Fisons Ltd | PHARMACEUTICAL MIXTURE OF 1,3-BIS- (2-CARBOXYCHROMONE-5-YL-OXY) -PROPANE-2-OL, OR ONE OF ITS SALTS, AND AT LEAST ONE BRONCHODILATOR |
US4515805A (en) * | 1980-11-05 | 1985-05-07 | Fisons Plc | Soluble sodium cromoglycate compositions |
US6632456B1 (en) | 1993-06-24 | 2003-10-14 | Astrazeneca Ab | Compositions for inhalation |
US6846801B1 (en) | 1993-06-24 | 2005-01-25 | Astrazeneca Ab | Systemic administration of a therapeutic preparation |
US6794357B1 (en) | 1993-06-24 | 2004-09-21 | Astrazeneca Ab | Compositions for inhalation |
US6371171B1 (en) | 1993-10-01 | 2002-04-16 | Astra Aktiebolag | Agglomeration of finely divided powders |
US5551489A (en) * | 1993-10-01 | 1996-09-03 | Astra Aktiebolag | Agglomeration of finely divided powders |
US8137657B2 (en) | 1993-10-26 | 2012-03-20 | Vectura Limited | Carrier particles for use in dry powder inhalers |
US6221338B1 (en) | 1993-10-26 | 2001-04-24 | Vectura Limited | Method of producing particles for use in dry powder inhalers |
US6582678B2 (en) | 1993-10-26 | 2003-06-24 | Vectura Limited | Carrier particles for use in dry powder inhalers |
US6955824B1 (en) | 1994-03-15 | 2005-10-18 | Glaxo Group Limited | Inhalation composition containing lactose pellets |
US6183782B1 (en) | 1994-03-15 | 2001-02-06 | Glaxo Group Limited | Inhalation composition containing lactose pellets |
US6102036A (en) * | 1994-04-12 | 2000-08-15 | Smoke-Stop | Breath activated inhaler |
US6610653B1 (en) | 1994-06-23 | 2003-08-26 | Astrazeneca Ab | Therapeutic preparation for inhalation |
US6524557B1 (en) | 1994-12-22 | 2003-02-25 | Astrazeneca Ab | Aerosol formulations of peptides and proteins |
US6436902B1 (en) | 1994-12-22 | 2002-08-20 | Astrazeneca Ab | Therapeutic preparations for inhalation |
EP2213279A3 (en) * | 1995-01-31 | 2010-10-13 | Vectura Limited | Improvements in and relating to carrier particles for use in dry powder inhalers |
US8920781B2 (en) | 1995-01-31 | 2014-12-30 | Vectura Limited | Carrier particles for use in dry powder inhalers |
US7011818B2 (en) | 1995-01-31 | 2006-03-14 | Vectura Limited | Carrier particles for use in dry powder inhalers |
EP1666023A2 (en) | 1995-01-31 | 2006-06-07 | Vectura Limited | Improvements in and relating to carrier particles for use in dry powder inhalers |
EP2258342A3 (en) * | 1995-01-31 | 2014-01-08 | Vectura Limited | Improvements in and relating to carrier particles for use in dry powder inhalers |
US6153224A (en) * | 1995-01-31 | 2000-11-28 | Co-Ordinated Drug Development Limited | Carrier particles for use in dry powder inhalers |
EP1666023B1 (en) * | 1995-01-31 | 2011-10-05 | Vectura Limited | Improvements in and relating to carrier particles for use in dry powder inhalers |
US7718163B2 (en) | 1995-01-31 | 2010-05-18 | Vectura Limited (01696917) | Carrier particles for use in dry powder inhalers |
US7399528B2 (en) | 1999-07-16 | 2008-07-15 | Chiesi Farmaceutici S.P.A. | Powder particles with smooth surface for use in inhalation therapy |
US8205614B2 (en) | 1999-09-04 | 2012-06-26 | Innovata Biomed Limited | Delivery device |
EP1719505A2 (en) | 2000-04-17 | 2006-11-08 | CHIESI FARMACEUTICI S.p.A. | Pharmaceutical formulations for dry powder inhalers in the form of hard pellets |
EP2272508A2 (en) | 2000-04-17 | 2011-01-12 | Vectura Limited | Pharmaceutical Formulations for Dry Powder Inhalers |
US7541022B2 (en) | 2000-04-17 | 2009-06-02 | Vectura Limited | Pharmaceutical formulations for dry powder inhalers |
US7223748B2 (en) | 2000-04-17 | 2007-05-29 | Chiesi Farmaceutici S.P.A. | Pharmaceutical formulations for dry powder inhalers in the form of hard-pellets |
US6884794B2 (en) | 2000-04-17 | 2005-04-26 | Chiesi Farmaceutici S.P.A. | Pharmaceutical formulations for dry powder inhalers in the form of hard-pellets |
US8871274B2 (en) | 2000-04-17 | 2014-10-28 | Vectura Limited | Pharmaceutical formulations for dry powder inhalers |
US9566239B2 (en) | 2000-04-17 | 2017-02-14 | Vectura Limited | Pharmaceutical formulations for dry powder inhalers |
US8800550B2 (en) | 2001-11-23 | 2014-08-12 | Innovata Biomed Limited | Medicament delivery assembly |
US7763280B2 (en) | 2002-11-28 | 2010-07-27 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Tiotropium containing powder formulation for inhalation |
US9987229B2 (en) | 2003-09-02 | 2018-06-05 | Norton Healthcare Ltd. | Process for preparing a medicament |
US8851069B2 (en) | 2004-04-21 | 2014-10-07 | Innovata Biomed Limited | Inhaler |
US8511302B2 (en) | 2004-04-24 | 2013-08-20 | Innovata Biomed Limited | Dose counter mechanisms for medicament delivery devices |
US8236979B2 (en) | 2008-07-24 | 2012-08-07 | American Air Liquide, Inc. | Methods for synthesis of heteroleptic cyclopentadienyl transition metal precursors |
US11116721B2 (en) | 2009-02-26 | 2021-09-14 | Glaxo Group Limited | Pharmaceutical formulations comprising 4-{(1R)-2-[(6-{2-[(2,6-dichlorobenzyl)oxy]ethoxy}hexyl)amino]-1-hydroxyethyl}-2-(hydroxymethyl) phenol |
US11090294B2 (en) | 2009-12-01 | 2021-08-17 | Glaxo Group Limited | Combinations of a muscarinic receptor antagonist and a beta-2 adrenoreceptor agonist |
WO2013104892A1 (en) | 2012-01-13 | 2013-07-18 | Hovione Inter Limited | Application of high dose compounds via inhalation |
EP4316473A2 (en) | 2013-03-28 | 2024-02-07 | Vectura Limited | Use of stearate in an inhalable formulation |
WO2020031119A1 (en) | 2018-08-07 | 2020-02-13 | Norton (Waterford) Limited | Application of raman spectroscopy for the manufacture of inhalation powders |
EP3910324A1 (en) | 2018-08-07 | 2021-11-17 | Norton (Waterford) Limited | Application of raman spectroscopy for the manufacture of inhalation powders |
Also Published As
Publication number | Publication date |
---|---|
MY7400329A (en) | 1974-12-31 |
DE1792207B2 (en) | 1977-10-13 |
BE718846A (en) | 1969-01-31 |
NL161984C (en) | 1980-04-15 |
DE1792207A1 (en) | 1971-11-04 |
NL161984B (en) | 1979-11-15 |
FI48973C (en) | 1975-03-10 |
DK123276B (en) | 1972-06-05 |
MY7400330A (en) | 1974-12-31 |
IE32343L (en) | 1969-02-08 |
FI48973B (en) | 1974-12-02 |
FR8142M (en) | 1970-08-17 |
JPS5643448B1 (en) | 1981-10-13 |
FR1605538A (en) | 1979-02-23 |
SE372420B (en) | 1974-12-23 |
NO128307B (en) | 1973-10-29 |
DE1792799A1 (en) | 1977-08-11 |
DE1792207C3 (en) | 1978-06-29 |
US3634582A (en) | 1972-01-11 |
IE32343B1 (en) | 1973-06-27 |
NL6811060A (en) | 1969-02-11 |
CA946280A (en) | 1974-04-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
GB1242211A (en) | Pharmaceutical composition | |
JP2974409B2 (en) | Particulate drug composition | |
EP0322137B1 (en) | Spray dried ibuprofen | |
US3882228A (en) | Analgesic formulations | |
CA2124568C (en) | Method for producing microgranulated particle | |
GB1381872A (en) | Pharmaceutical compositions for inhalation | |
MX9404762A (en) | COMPOSITIONS FOR INHALATION AND PROCESS FOR ITS PREPARATION. | |
US4757090A (en) | Direct tableting acetaminophen compositions | |
US4661521A (en) | Direct tableting acetaminophen compositions | |
CA2125685A1 (en) | Powders for inhalation and process for preparing them | |
CA2430318A1 (en) | Powder formulation and method for producing the same | |
EP1036562A1 (en) | Soft-pellet drug and process for the preparation thereof | |
AU1434700A (en) | Dry powder pharmaceutical formulation | |
GB934089A (en) | Improvements in or relating to sustained release medicaments | |
KR20000070189A (en) | New Formulation for Inhalation Having a Poured Bulk Density of from 0.28 to 0.38 g/㎖, Comprising Terbutaline Sulphate, a Process for Preparing the Formulation and the Use Thereof | |
JPH0399014A (en) | Riboflavin granule containing no auxiliaries | |
JPS63112519A (en) | Production of nifedipine preparation | |
JP5034226B2 (en) | Solid formulation with stabilized ingredients | |
GB644081A (en) | Improvements in pectin products and the process of making same | |
JPH0967247A (en) | Production of medicinal preparation of uniformly fine particle | |
GB1511852A (en) | Reconstitutable powders | |
GB1468815A (en) | Pharmaceutical compositions | |
JPS6271552A (en) | Fine granulation of organic compound | |
JPH02231419A (en) | Manufacture of particle improved in fluidity, shelf stability, and pharmaceutical property, and drug containing said particle | |
ES413624A3 (en) | A method for preparing a phymaceutical composition in easy fluidizable powder, specially intended for the treatment by inhalation of allergic diseases of the respiratory tract. (Machine-translation by Google Translate, not legally binding) |