ATE209903T1 - Verfahren i - Google Patents

Verfahren i

Info

Publication number
ATE209903T1
ATE209903T1 AT94929076T AT94929076T ATE209903T1 AT E209903 T1 ATE209903 T1 AT E209903T1 AT 94929076 T AT94929076 T AT 94929076T AT 94929076 T AT94929076 T AT 94929076T AT E209903 T1 ATE209903 T1 AT E209903T1
Authority
AT
Austria
Prior art keywords
agglomerates
procedure
spheronizing
spheronization
agglomerating
Prior art date
Application number
AT94929076T
Other languages
English (en)
Inventor
Eva Trofast
Johan Falk
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9303214A external-priority patent/SE9303214D0/xx
Priority claimed from SE9304271A external-priority patent/SE9304271D0/xx
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of ATE209903T1 publication Critical patent/ATE209903T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1688Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/20Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by expressing the material, e.g. through sieves and fragmenting the extruded length

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Control Of Multiple Motors (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Control Of Motors That Do Not Use Commutators (AREA)
  • Exchange Systems With Centralized Control (AREA)
  • Stereophonic System (AREA)
  • Glanulating (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Mixers Of The Rotary Stirring Type (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
AT94929076T 1993-10-01 1994-09-29 Verfahren i ATE209903T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
SE9303214A SE9303214D0 (sv) 1993-10-01 1993-10-01 Process I
SE9304271A SE9304271D0 (sv) 1993-12-22 1993-12-22 Process I
PCT/SE1994/000896 WO1995009615A1 (en) 1993-10-01 1994-09-29 Process i
US08/317,033 US5551489A (en) 1993-10-01 1994-10-03 Agglomeration of finely divided powders

Publications (1)

Publication Number Publication Date
ATE209903T1 true ATE209903T1 (de) 2001-12-15

Family

ID=27355730

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94929076T ATE209903T1 (de) 1993-10-01 1994-09-29 Verfahren i

Country Status (23)

Country Link
US (1) US5551489A (de)
EP (1) EP0721331B1 (de)
JP (1) JP3732508B2 (de)
CN (1) CN1110300C (de)
AT (1) ATE209903T1 (de)
AU (1) AU679789B2 (de)
BR (1) BR9407686A (de)
CZ (1) CZ289214B6 (de)
DE (1) DE69429357T2 (de)
DK (1) DK0721331T3 (de)
EG (1) EG20677A (de)
ES (1) ES2166786T3 (de)
FI (1) FI116364B (de)
HU (1) HU222355B1 (de)
IL (1) IL111080A (de)
NO (1) NO314836B1 (de)
NZ (1) NZ274277A (de)
PL (1) PL175564B1 (de)
PT (1) PT721331E (de)
RU (1) RU2170082C2 (de)
SG (1) SG48049A1 (de)
SK (1) SK283569B6 (de)
WO (1) WO1995009615A1 (de)

Families Citing this family (90)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9404945D0 (en) 1994-03-15 1994-04-27 Glaxo Group Ltd Pharmaceutical composition
SE9700136D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
US5983956A (en) * 1994-10-03 1999-11-16 Astra Aktiebolag Formulation for inhalation
US5980949A (en) * 1994-10-03 1999-11-09 Astra Aktiebolag Formulation for inhalation
SE9700134D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
US5654007A (en) * 1995-06-07 1997-08-05 Inhale Therapeutic Systems Methods and system for processing dispersible fine powders
DE19522899C1 (de) * 1995-06-23 1996-12-19 Hexal Pharmaforschung Gmbh Verfahren zum kontinuierlichen Ersintern eines Granulats
US5826633A (en) 1996-04-26 1998-10-27 Inhale Therapeutic Systems Powder filling systems, apparatus and methods
US20020052310A1 (en) * 1997-09-15 2002-05-02 Massachusetts Institute Of Technology The Penn State Research Foundation Particles for inhalation having sustained release properties
US5874064A (en) 1996-05-24 1999-02-23 Massachusetts Institute Of Technology Aerodynamically light particles for pulmonary drug delivery
US6652837B1 (en) 1996-05-24 2003-11-25 Massachusetts Institute Of Technology Preparation of novel particles for inhalation
GB9616047D0 (en) * 1996-07-31 1996-09-11 Glaxo Group Ltd Medicament carrier with agglomerated large medicament particles and related method of manufacture thereof
SE9700133D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
SE9700135D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
CA2706634C (en) * 1997-03-20 2012-10-23 Schering Corporation Preparation of powder agglomerates
US6503537B2 (en) 1997-03-20 2003-01-07 Schering Corporation Preparation of powder agglomerates
US6495167B2 (en) 1997-03-20 2002-12-17 Schering Corporation Preparation of powder agglomerates
EP0876814A1 (de) 1997-05-07 1998-11-11 "PHARLYSE", Société Anonyme Trägerstoff für Trockenpulverinhalator, Verfahren zu dessen Herstellung und diesen enthaltende Arzneimittel
US6182712B1 (en) 1997-07-21 2001-02-06 Inhale Therapeutic Systems Power filling apparatus and methods for their use
US7052678B2 (en) 1997-09-15 2006-05-30 Massachusetts Institute Of Technology Particles for inhalation having sustained release properties
AU2081999A (en) * 1998-01-13 1999-08-02 Astrazeneca Uk Limited Pharmaceutical compostition comprising a compound having dopamine (D2) receptor agonist activity and a compound (B) having Beta2 adrenoreceptor agonist activity
SE9802073D0 (sv) 1998-06-11 1998-06-11 Astra Ab New use
US6956021B1 (en) * 1998-08-25 2005-10-18 Advanced Inhalation Research, Inc. Stable spray-dried protein formulations
US8722668B2 (en) * 1998-12-23 2014-05-13 Daryl W. Hochman Methods and compositions for the treatment of neuropathic pain and neuropsychiatric disorders
US6749835B1 (en) 1999-08-25 2004-06-15 Advanced Inhalation Research, Inc. Formulation for spray-drying large porous particles
US20010036481A1 (en) * 1999-08-25 2001-11-01 Advanced Inhalation Research, Inc. Modulation of release from dry powder formulations
US7678364B2 (en) 1999-08-25 2010-03-16 Alkermes, Inc. Particles for inhalation having sustained release properties
EP1210067A2 (de) * 1999-08-25 2002-06-05 Advanced Inhalation Research, Inc. Modulation der freigabe aus trockenpulverformulierungen
US7304750B2 (en) 1999-12-17 2007-12-04 Nektar Therapeutics Systems and methods for non-destructive mass sensing
US6499984B1 (en) * 2000-05-22 2002-12-31 Warner-Lambert Company Continuous production of pharmaceutical granulation
JP2005504715A (ja) * 2000-12-29 2005-02-17 アドバンスト インハレーション リサーチ,インコーポレイテッド 持続放出特性を有する吸入用粒子
US20020141946A1 (en) * 2000-12-29 2002-10-03 Advanced Inhalation Research, Inc. Particles for inhalation having rapid release properties
US7659404B2 (en) 2001-02-14 2010-02-09 Tibotec Pharmaceuticals Ltd. Broad spectrum 2-(substituted-amino)-benzothiazole sulfonamide HIV protease inhibitors
PL367084A1 (en) 2001-04-09 2005-02-21 Tibotec Pharmaceuticals Ltd. Broadspectrum 2-(substituted-amino)-benzoxazole sulfonamide hiv protease inhibitors
WO2002092595A1 (en) 2001-05-11 2002-11-21 Tibotec Pharmaceuticals Ltd. Broadspectrum 2-amino-benzoxazole sulfonamide hiv protease inhibitors
US20030129250A1 (en) * 2001-11-20 2003-07-10 Advanced Inhalation Research Inc. Particulate compositions for improving solubility of poorly soluble agents
PT1455755E (pt) * 2001-11-20 2013-06-18 Civitas Therapeutics Inc Composições particuladas melhoradas para distribuição pulmonar
BR0215260A (pt) 2001-12-21 2004-12-07 Tibotec Pharm Ltd Inibidores de hiv protease de sulfonamida contendo fenila substituìda heterocìclica de amplo espectro
MY142238A (en) 2002-03-12 2010-11-15 Tibotec Pharm Ltd Broadspectrum substituted benzimidazole sulfonamide hiv protease inhibitors
DE60315984T2 (de) 2002-05-17 2008-05-29 Tibotec Pharmaceuticals Ltd. Substituierte benzisoxazolsulfonamide mit breitbändiger hiv-protease hemmender wirkung
CA2493940C (en) 2002-08-14 2011-11-22 Tibotec Pharmaceuticals Ltd. Broadspectrum substituted oxindole sulfonamide hiv protease inhibitors
EP1417958A1 (de) * 2002-11-08 2004-05-12 Pari GmbH Feuchtgranulierungsverfahren
SG145742A1 (en) 2003-09-11 2008-09-29 Tibotec Pharm Ltd Entry inhibitors of the hiv virus
SE528121C2 (sv) * 2004-03-29 2006-09-05 Mederio Ag Preparering av torrpulver för på förhand uppmätt DPI
AR048650A1 (es) 2004-05-04 2006-05-10 Tibotec Pharm Ltd Derivados de (1,10b-dihidro-2-(aminocarbonil-fenil)-5h-pirazolo[1,5 c][1,3]benzoxazin-5-il)fenil metanona como inhibidores de la replicacion viral del vih
JP5073480B2 (ja) 2004-05-07 2012-11-14 セコイア、ファーマシューティカルズ、インコーポレイテッド 耐性防止レトロウイルスプロテアーゼ阻害薬
AP2006003791A0 (en) 2004-05-17 2006-10-31 Tibotec Pharm Ltd 1-Heterocyclyl-1,5-dihydro-pyridoÄ3,2-BÜindol-2-ones
RU2377243C2 (ru) 2004-05-17 2009-12-27 Тиботек Фармасьютикалз Лтд. 6,7,8,9-ЗАМЕЩЕННЫЕ 1-ФЕНИЛ-1,5-ДИГИДРОПИРИДО (3,2-b) ИНДОЛ-2-ОНЫ, ПОЛЕЗНЫЕ В КАЧЕСТВЕ АНТИИНФЕКЦИОННЫХ ФАРМАЦЕВТИЧЕСКИХ СРЕДСТВ
MXPA06013315A (es) 2004-05-17 2007-02-02 Tibotec Pharm Ltd 1,5-dihidro-pirido[3,2-b]indol-2-onas 4-sustituidas.
TW200710091A (en) 2005-04-11 2007-03-16 Tibotec Pharm Ltd (1,10B-dihydro-2-(aminoalkyl-phenyl)-5H-pyrazolo [1,5-c][1,3]benzoxazin-5-yl)phenyl methanone derivatives as HIV viral replication inhibitors
EP1940856B1 (de) 2005-10-21 2014-10-08 Universiteit Antwerpen Neue urokinaseinhibitoren
WO2007113290A1 (en) 2006-04-03 2007-10-11 Tibotec Pharmaceuticals Ltd. Hiv inhibiting 3,4-dihydro-imidazo[4,5-b]pyridin-5-ones
DE102007049931A1 (de) 2007-10-18 2009-04-23 Pharmatech Gmbh Vorrichtung und Verfahren zur kontinuierlichen Herstellung von sphärischen Pulveragglomeraten
EP2116236A1 (de) 2008-04-21 2009-11-11 Université de Mons-Hainaut Bisbenzamidinderivate als Antioxidationsmittel
MX2011011122A (es) * 2009-04-24 2011-11-04 Schering Corp Formulaciones de aglomerados que incluyen agentes farmaceuticos activos con tamaños de particula objetivo.
BR112012021889B1 (pt) 2010-03-02 2022-01-11 Ph Pharma Co., Ltd Compostos de amidas heterocíclicas e composição que as compreende para a prevenção ou o tratamento de doenças oculares
US20110224229A1 (en) 2010-03-10 2011-09-15 Astrazeneca Ab Novel Crystalline Form
GB201019043D0 (en) 2010-11-10 2010-12-22 Protea Biopharma N V Use of 2',5'-oligoadenylate derivative compounds
GB201102237D0 (en) 2011-02-09 2011-03-23 Kuecept Ltd Particle formulation
GB201108225D0 (en) 2011-05-17 2011-06-29 Amakem Nv Novel KBC inhibitors
GB201113689D0 (en) 2011-08-09 2011-09-21 Amakem Nv Novel PDE4 inhibitors
GB201114854D0 (en) 2011-08-29 2011-10-12 Amakem Nv Novel rock inhibitors
MX2014002395A (es) 2011-08-31 2014-06-05 Amakem Nv Inhibidores de rock suaves, novedosos.
US9090630B2 (en) 2011-09-30 2015-07-28 Oncodesign S.A. Macrocyclic FLT3 kinase inhibitors
JP6082397B2 (ja) 2011-09-30 2017-02-15 イプセン ファルマ ソシエテ パール アクシオン サンプリフィエIpsen Pharma S.A.S. マクロ環状lrrk2キナーゼ阻害剤
EP2810198B1 (de) 2012-01-30 2023-07-12 Universiteit Gent Antiinvasive verbindungen
GB201204756D0 (en) 2012-03-19 2012-05-02 Lewi Paulus J Triazines with suitable spacers for treatment and/or prevention of HIV infections
WO2014072419A1 (en) 2012-11-08 2014-05-15 Universiteit Antwerpen Novel anti-hiv compounds
AU2014230125A1 (en) 2013-03-15 2015-10-29 Oncodesign S.A. Macrocyclic salt-inducible kinase inhibitors
US9427376B2 (en) * 2013-10-10 2016-08-30 Chiesi Farmaceutici S.P.A. Process for preparing pharmaceutical formulations for inhalation comprising a high-dosage strength active ingredient
WO2015150337A1 (en) 2014-04-01 2015-10-08 Amakem Nv Lim kinase inhibitors
EP3180003B1 (de) 2014-07-01 2022-01-12 The Regents of the University of California Pkc-epsilon-inhibitoren
EP3166955B1 (de) 2014-07-08 2018-05-02 Universiteit Gent Hamamelitanninanaloga und verwendungen davon
JP2017529365A (ja) 2014-09-17 2017-10-05 オンコデザイン エス.ア. 大環状lrrk2キナーゼ阻害剤
CA2958782C (en) 2014-09-17 2024-01-09 Oncodesign S.A. Macrocyclic rip2 kinase inhibitors
WO2016083490A1 (en) 2014-11-27 2016-06-02 Remynd Nv Compounds for the treatment of amyloid-associated diseases
WO2016146651A1 (en) 2015-03-16 2016-09-22 Oncodesign Sa Macrocyclic activin-like receptor kinase inhibitors
WO2017146994A1 (en) * 2016-02-24 2017-08-31 Merck Sharp & Dohme Corp. Controlled agglomeration of micronized drug or drug-excipient mixtures
WO2017157882A1 (en) 2016-03-14 2017-09-21 Université Catholique de Louvain Serine biosynthetic pathway inhibitors
WO2018065387A1 (en) 2016-10-04 2018-04-12 Universiteit Gent Novel hamamelitannin analogues and uses thereof
EP3544952B1 (de) 2016-11-24 2024-11-06 Universiteit Antwerpen Halogenierte benzotropolone als atg4b-inhibitoren
WO2018138358A1 (en) 2017-01-30 2018-08-02 Université de Liège Perk and ire-1a inhibitors against neurodevelopmental disorders
PL3621963T3 (pl) 2017-05-11 2024-05-20 Remynd N.V. Związki do leczenia epilepsji, zaburzeń neurodegeneracyjnych i innych zaburzeń oun
US20210145838A1 (en) 2018-04-05 2021-05-20 Universiteit Hasselt Selective pde4d inhibitors against demyelinating diseases
US20210292766A1 (en) 2018-08-29 2021-09-23 University Of Massachusetts Inhibition of Protein Kinases to Treat Friedreich Ataxia
JP7370032B2 (ja) 2019-05-14 2023-10-27 スーヂョウ フォー ヘルス ファーマスーティカルズ カンパニー リミテッド Parr阻害剤としてのキナゾリン―2.4―ジオン誘導体
WO2022157381A1 (en) 2021-01-25 2022-07-28 Universiteit Hasselt Phloretin for use in the treatment of neurodegenerative and demyelinating diseases
WO2023021132A1 (en) 2021-08-18 2023-02-23 Katholieke Universiteit Leuven 6-substituted- and 6,7-disubstituted-7-deazapurine ribonucleoside analogues
EP4405357A1 (de) 2021-09-23 2024-07-31 Katholieke Universiteit Leuven KU Leuven Research & Development Ribonukleosidanaloga gegen -sars-cov-2
WO2023241799A1 (en) 2022-06-15 2023-12-21 Université Libre de Bruxelles Flavanols for use in the treatment of retroviral infections

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2609150A (en) * 1949-11-05 1952-09-02 Union Carbide & Carbon Corp Mechanical pulverization of refrigerated plastics
NL258520A (de) * 1960-03-25 1900-01-01
GB1242211A (en) * 1967-08-08 1971-08-11 Fisons Pharmaceuticals Ltd Pharmaceutical composition
US3802822A (en) * 1972-03-01 1974-04-09 Mars Mineral Corp Pelletizer
GB1569611A (en) * 1976-01-23 1980-06-18 Fisons Ltd Pelletised or granular medicament formulation
GB1520247A (en) * 1974-08-10 1978-08-02 Fisons Ltd Pelletised medicament formulations
US4161516A (en) * 1975-07-25 1979-07-17 Fisons Limited Composition for treating airway disease
US4161526A (en) * 1978-07-20 1979-07-17 Sterling Drug Inc. Zinc salt prevention or removal of discoloration in pyrithione, pyrithione salt and dipyrithione compositions
DE3268533D1 (en) * 1981-07-24 1986-02-27 Fisons Plc Inhalation drugs, methods for their production and pharmaceutical formulations containing them
US4688610A (en) * 1985-03-19 1987-08-25 Spiral Systems Inc. Apparatus for dispensing particulate agglomerating solids
US4940556A (en) * 1986-01-30 1990-07-10 Syntex (U.S.A.) Inc. Method of preparing long acting formulation
GB8606762D0 (en) * 1986-03-19 1986-04-23 Boots Co Plc Therapeutic agents
JPS63116732A (ja) * 1986-11-06 1988-05-21 Fukae Kogyo Kk 粉粒体処理装置
GB8711005D0 (en) * 1987-05-09 1987-06-10 British Petroleum Co Plc Chemical process
ATE94801T1 (de) * 1990-01-29 1993-10-15 Ciba Geigy Ag Verfahren und vorrichtung zur dosierung eines feinkoernigen pulvers.
GB9027018D0 (en) * 1990-12-12 1991-01-30 Ici Plc Heterocyclic compounds
US5394868A (en) * 1992-06-25 1995-03-07 Schering Corporation Inhalation device for powdered medicaments

Also Published As

Publication number Publication date
NO961290D0 (no) 1996-03-29
SK39196A3 (en) 1997-06-04
DE69429357D1 (de) 2002-01-17
DE69429357T2 (de) 2002-08-14
SG48049A1 (en) 1998-04-17
AU7826194A (en) 1995-05-01
DK0721331T3 (da) 2002-02-11
US5551489A (en) 1996-09-03
HUT74519A (en) 1997-01-28
CZ289214B6 (cs) 2001-12-12
PL175564B1 (pl) 1999-01-29
RU2170082C2 (ru) 2001-07-10
IL111080A (en) 1999-08-17
JPH09504224A (ja) 1997-04-28
PL313765A1 (en) 1996-07-22
FI116364B (fi) 2005-11-15
PT721331E (pt) 2002-05-31
EG20677A (en) 1999-11-30
SK283569B6 (sk) 2003-09-11
JP3732508B2 (ja) 2006-01-05
HU222355B1 (hu) 2003-06-28
FI961430A (fi) 1996-03-29
CZ94296A3 (en) 1996-06-12
AU679789B2 (en) 1997-07-10
EP0721331A1 (de) 1996-07-17
CN1132476A (zh) 1996-10-02
FI961430A0 (fi) 1996-03-29
NO314836B1 (no) 2003-06-02
IL111080A0 (en) 1994-11-28
ES2166786T3 (es) 2002-05-01
EP0721331B1 (de) 2001-12-05
CN1110300C (zh) 2003-06-04
BR9407686A (pt) 1997-02-04
NZ274277A (en) 1998-01-26
NO961290L (no) 1996-03-29
HU9600821D0 (en) 1996-05-28
WO1995009615A1 (en) 1995-04-13

Similar Documents

Publication Publication Date Title
DE69429357D1 (de) Verfahren i
CA2220169A1 (en) Improved methods for the manufacture of magnetically responsive particles
MX9709448A (es) Metodos y sistemas para procesar polvos finos dispersables.
DE3473067D1 (en) Apparatus for charging, and transporting toner particles
GB1497732A (en) Carrier particles suitable for electrostatographic developers
DE69417678D1 (de) Magnetischer Entwickler, Prozesskassette und Bildherstellungsverfahren
NO20005198D0 (no) FremgangsmÕte for separasjon av magnetiske partikler blandet i fluid, samt separasjonssystem og separator
EP0130043A3 (en) Magnetizable adsorbents
MY114295A (en) Suspending agent-containing slurry, method of producing the same, and process for suspension polymerization using the same
CS21192A3 (en) Complex containing precipitation factor ix
AU581530B2 (en) Process for the preparation of granules and granules obtained by this process
NZ509067A (en) Densifying of a bulk particulate material
DE3363380D1 (en) Laser nephelometer for the detection of antigenes and antibodies
AU6849590A (en) Magnetizable microspheres based on polysilsesquioxane, the process for their preparation and their application in biology
EP0834560A4 (de) Feine magnetische partikel zur bindung nutzlicher proteine verfahren zu deren herstellung und anwendung
EP0669135A4 (de) Granulierte zubereitung für mri.
MX9504457A (es) Polvo de flujo libre para moldeo que comprende politetrafluoroetileno.
GR3025182T3 (en) Spheroidal particles useful for electrostatography.
EP0306330A3 (de) Toner und Verfahren zu seiner Herstellung
CZ1195A3 (en) Process for preparing bulk particulate ammonium nitrate and coated particles thereof
MY103476A (en) Selenium sulfide shampoos containing low levels of nonionic polymers to prevent agglomeration
EP0641587A3 (de) Verfahren zum Auftrennen einer Dispersion von Partikeln in Flüssigkeiten in einen mit Partikeln angereicherten und einen an Partikeln verarmten Teilstrom.
EP0057585A3 (de) Entwicklergemisch
EA199800216A1 (ru) Полиизоцианатные частицы регулируемого размера и распределения частиц по размеру
Rudinger et al. Motion of small particles in a field of oscillating shock waves

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 0721331

Country of ref document: EP