SK283569B6 - Spôsob spracovania jemne deleného práškového liečiva, zariadenie na vykonávanie tohto spôsobu a aglomeráty vyrobené týmto spôsobom - Google Patents

Spôsob spracovania jemne deleného práškového liečiva, zariadenie na vykonávanie tohto spôsobu a aglomeráty vyrobené týmto spôsobom Download PDF

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Publication number
SK283569B6
SK283569B6 SK391-96A SK39196A SK283569B6 SK 283569 B6 SK283569 B6 SK 283569B6 SK 39196 A SK39196 A SK 39196A SK 283569 B6 SK283569 B6 SK 283569B6
Authority
SK
Slovakia
Prior art keywords
agglomerates
finely divided
screw feeder
spheronization
divided powdered
Prior art date
Application number
SK391-96A
Other languages
English (en)
Slovak (sk)
Other versions
SK39196A3 (en
Inventor
Eva Trofast
Johan Falk
Original Assignee
Astra Aktiebolag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9303214A external-priority patent/SE9303214D0/xx
Priority claimed from SE9304271A external-priority patent/SE9304271D0/xx
Application filed by Astra Aktiebolag filed Critical Astra Aktiebolag
Publication of SK39196A3 publication Critical patent/SK39196A3/sk
Publication of SK283569B6 publication Critical patent/SK283569B6/sk

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1688Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/20Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by expressing the material, e.g. through sieves and fragmenting the extruded length

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Otolaryngology (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Control Of Multiple Motors (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Stereophonic System (AREA)
  • Control Of Motors That Do Not Use Commutators (AREA)
  • Exchange Systems With Centralized Control (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Mixers Of The Rotary Stirring Type (AREA)
  • General Preparation And Processing Of Foods (AREA)
SK391-96A 1993-10-01 1994-09-29 Spôsob spracovania jemne deleného práškového liečiva, zariadenie na vykonávanie tohto spôsobu a aglomeráty vyrobené týmto spôsobom SK283569B6 (sk)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
SE9303214A SE9303214D0 (sv) 1993-10-01 1993-10-01 Process I
SE9304271A SE9304271D0 (sv) 1993-12-22 1993-12-22 Process I
PCT/SE1994/000896 WO1995009615A1 (en) 1993-10-01 1994-09-29 Process i
US08/317,033 US5551489A (en) 1993-10-01 1994-10-03 Agglomeration of finely divided powders

Publications (2)

Publication Number Publication Date
SK39196A3 SK39196A3 (en) 1997-06-04
SK283569B6 true SK283569B6 (sk) 2003-09-11

Family

ID=27355730

Family Applications (1)

Application Number Title Priority Date Filing Date
SK391-96A SK283569B6 (sk) 1993-10-01 1994-09-29 Spôsob spracovania jemne deleného práškového liečiva, zariadenie na vykonávanie tohto spôsobu a aglomeráty vyrobené týmto spôsobom

Country Status (23)

Country Link
US (1) US5551489A (de)
EP (1) EP0721331B1 (de)
JP (1) JP3732508B2 (de)
CN (1) CN1110300C (de)
AT (1) ATE209903T1 (de)
AU (1) AU679789B2 (de)
BR (1) BR9407686A (de)
CZ (1) CZ289214B6 (de)
DE (1) DE69429357T2 (de)
DK (1) DK0721331T3 (de)
EG (1) EG20677A (de)
ES (1) ES2166786T3 (de)
FI (1) FI116364B (de)
HU (1) HU222355B1 (de)
IL (1) IL111080A (de)
NO (1) NO314836B1 (de)
NZ (1) NZ274277A (de)
PL (1) PL175564B1 (de)
PT (1) PT721331E (de)
RU (1) RU2170082C2 (de)
SG (1) SG48049A1 (de)
SK (1) SK283569B6 (de)
WO (1) WO1995009615A1 (de)

Families Citing this family (89)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9404945D0 (en) * 1994-03-15 1994-04-27 Glaxo Group Ltd Pharmaceutical composition
SE9700136D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
US5983956A (en) * 1994-10-03 1999-11-16 Astra Aktiebolag Formulation for inhalation
SE9700134D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
US5980949A (en) * 1994-10-03 1999-11-09 Astra Aktiebolag Formulation for inhalation
US5654007A (en) * 1995-06-07 1997-08-05 Inhale Therapeutic Systems Methods and system for processing dispersible fine powders
DE19522899C1 (de) * 1995-06-23 1996-12-19 Hexal Pharmaforschung Gmbh Verfahren zum kontinuierlichen Ersintern eines Granulats
US5826633A (en) 1996-04-26 1998-10-27 Inhale Therapeutic Systems Powder filling systems, apparatus and methods
US6652837B1 (en) 1996-05-24 2003-11-25 Massachusetts Institute Of Technology Preparation of novel particles for inhalation
US5874064A (en) * 1996-05-24 1999-02-23 Massachusetts Institute Of Technology Aerodynamically light particles for pulmonary drug delivery
US20020052310A1 (en) * 1997-09-15 2002-05-02 Massachusetts Institute Of Technology The Penn State Research Foundation Particles for inhalation having sustained release properties
SE9700135D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
SE9700133D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
US6495167B2 (en) 1997-03-20 2002-12-17 Schering Corporation Preparation of powder agglomerates
US6503537B2 (en) 1997-03-20 2003-01-07 Schering Corporation Preparation of powder agglomerates
CZ295460B6 (cs) * 1997-03-20 2005-08-17 Schering Corporation Způsob výroby aglomerátů a jednotková dávka farmakologicky aktivní látky je obsahující
EP0876814A1 (de) * 1997-05-07 1998-11-11 "PHARLYSE", Société Anonyme Trägerstoff für Trockenpulverinhalator, Verfahren zu dessen Herstellung und diesen enthaltende Arzneimittel
US6182712B1 (en) 1997-07-21 2001-02-06 Inhale Therapeutic Systems Power filling apparatus and methods for their use
US7052678B2 (en) 1997-09-15 2006-05-30 Massachusetts Institute Of Technology Particles for inhalation having sustained release properties
JP2002509119A (ja) * 1998-01-13 2002-03-26 アストラゼネカ ユーケイ リミテッド ドーパミン(D2)レセプターアゴニスト活性を有する化合物およびβ2−アドレナリンレセプターアゴニスト活性を有する化合物(B)を含有する薬学的組成物
SE9802073D0 (sv) 1998-06-11 1998-06-11 Astra Ab New use
US6956021B1 (en) 1998-08-25 2005-10-18 Advanced Inhalation Research, Inc. Stable spray-dried protein formulations
US8722668B2 (en) * 1998-12-23 2014-05-13 Daryl W. Hochman Methods and compositions for the treatment of neuropathic pain and neuropsychiatric disorders
WO2001013891A2 (en) * 1999-08-25 2001-03-01 Advanced Inhalation Research, Inc. Modulation of release from dry powder formulations
US6749835B1 (en) 1999-08-25 2004-06-15 Advanced Inhalation Research, Inc. Formulation for spray-drying large porous particles
US7678364B2 (en) 1999-08-25 2010-03-16 Alkermes, Inc. Particles for inhalation having sustained release properties
US20010036481A1 (en) * 1999-08-25 2001-11-01 Advanced Inhalation Research, Inc. Modulation of release from dry powder formulations
US7304750B2 (en) 1999-12-17 2007-12-04 Nektar Therapeutics Systems and methods for non-destructive mass sensing
US6499984B1 (en) * 2000-05-22 2002-12-31 Warner-Lambert Company Continuous production of pharmaceutical granulation
EP1345629A2 (de) 2000-12-29 2003-09-24 Advanced Inhalation Research, Inc. Inhalationspartikel mit verzögerter freigabe
US20020141946A1 (en) * 2000-12-29 2002-10-03 Advanced Inhalation Research, Inc. Particles for inhalation having rapid release properties
CN101230067B (zh) 2001-02-14 2011-06-15 泰博特克药品有限公司 广谱的2-(取代-氨基)-苯并噻唑磺酰胺hiv蛋白酶抑制剂
AR035819A1 (es) 2001-04-09 2004-07-14 Tibotec Pharm Ltd 2-(amino sustituido)-benzoxazol sulfonamidas, inhibidoras de la proteasa del hiv, composiciones farmaceuticas que comprenden dichos compuestos, metodo in vitro para inhibir la replicacion retroviral y uso de dichos compuestos en la fabricacion de medicamentos
AU2002310818B2 (en) 2001-05-11 2007-12-13 Tibotec Pharmaceuticals Ltd. Broadspectrum 2-amino-benzoxazole sulfonamide HIV protease inhibitors
WO2003043585A2 (en) * 2001-11-20 2003-05-30 Advanced Inhalation Research, Inc. Improved particulate compositions for pulmonary delivery
AU2002346472A1 (en) * 2001-11-20 2003-06-10 Advanced Inhalation Research, Inc. Particulate compositions for improving solubility of poorly soluble agents
KR100942743B1 (ko) 2001-12-21 2010-02-16 티보텍 파마슈티칼즈 리미티드 광범위 스펙트럼 헤테로사이클릭 치환된 페닐 포함설폰아미드 hiv 프로테아제 저해제
MY142238A (en) 2002-03-12 2010-11-15 Tibotec Pharm Ltd Broadspectrum substituted benzimidazole sulfonamide hiv protease inhibitors
KR101019648B1 (ko) 2002-05-17 2011-03-07 티보텍 파마슈티컬즈 광범위 스펙트럼의 치환된 벤즈이속사졸 설폰아미드hiv 프로테아제 저해제
CN1688586B (zh) 2002-08-14 2012-05-09 泰博特克药品有限公司 取代的羟吲哚磺酰胺类广谱hiv蛋白酶抑制剂
EP1417958A1 (de) * 2002-11-08 2004-05-12 Pari GmbH Feuchtgranulierungsverfahren
EP1667675B1 (de) 2003-09-11 2011-11-09 Tibotec Pharmaceuticals Mittel zur hemmung des eintritts des hiv-virus
SE528121C2 (sv) * 2004-03-29 2006-09-05 Mederio Ag Preparering av torrpulver för på förhand uppmätt DPI
AR048650A1 (es) 2004-05-04 2006-05-10 Tibotec Pharm Ltd Derivados de (1,10b-dihidro-2-(aminocarbonil-fenil)-5h-pirazolo[1,5 c][1,3]benzoxazin-5-il)fenil metanona como inhibidores de la replicacion viral del vih
CN1997363B (zh) 2004-05-07 2012-03-28 塞阔伊亚药品公司 抗耐药性反转录病毒蛋白酶抑制剂
US7622582B2 (en) 2004-05-17 2009-11-24 Tibotec Bvba Derivatives of 1-phenyl-benzofuro[3,2]pyridin-2(1H)-one
US7622581B2 (en) 2004-05-17 2009-11-24 Tibotec Pharmaceuticals Ltd. 6,7,8,9-substituted 1-phenyl-1,5-dihydro-pyrido[3,2-b]indol-2-ones useful as anti-infective pharmaceutical agents
BRPI0511175A (pt) 2004-05-17 2007-12-04 Tibotec Pharm Ltd 1-hetero-ciclil-1,5-diidro-pirido[3,2-b]indol-2-onas
AR056652A1 (es) 2005-04-11 2007-10-17 Tibotec Pharm Ltd Derivados de (1,10-b dihidro-2-(aminoalquil-fenil) -5h-pirazolo (1,5-c) (1,3)benzoxazin-5-il) fenilmetanona y su uso en la fabricacion de un medicamento
EP1940856B1 (de) 2005-10-21 2014-10-08 Universiteit Antwerpen Neue urokinaseinhibitoren
EP2004647A1 (de) 2006-04-03 2008-12-24 Tibotec Pharmaceuticals Ltd. Hiv-inhibierende 3,4-dihydroimidazo[4,5-b]pyridin-5-one
DE102007049931A1 (de) 2007-10-18 2009-04-23 Pharmatech Gmbh Vorrichtung und Verfahren zur kontinuierlichen Herstellung von sphärischen Pulveragglomeraten
EP2116236A1 (de) 2008-04-21 2009-11-11 Université de Mons-Hainaut Bisbenzamidinderivate als Antioxidationsmittel
US20120097160A1 (en) * 2009-04-24 2012-04-26 Schering Corporation Agglomerate formulations including active pharmaceutical agents with targeted particle sizes
NZ602191A (en) 2010-03-02 2014-07-25 Amakem Nv Heterocyclic amides as rock inhibitors
WO2011110852A1 (en) 2010-03-10 2011-09-15 Astrazeneca Ab Polymorphic forms of 6- [2- (4 -cyanophenyl) - 2h - pyrazol - 3 - yl] - 5 -methyl - 3 - oxo - 4 - (trifluoromethyl - phenyl) 3,4-dihydropyrazine-2-carboxylic acid ethylamide
GB201019043D0 (en) 2010-11-10 2010-12-22 Protea Biopharma N V Use of 2',5'-oligoadenylate derivative compounds
GB201102237D0 (en) 2011-02-09 2011-03-23 Kuecept Ltd Particle formulation
GB201108225D0 (en) 2011-05-17 2011-06-29 Amakem Nv Novel KBC inhibitors
GB201113689D0 (en) 2011-08-09 2011-09-21 Amakem Nv Novel PDE4 inhibitors
GB201114854D0 (en) 2011-08-29 2011-10-12 Amakem Nv Novel rock inhibitors
SG11201400117QA (en) 2011-08-31 2014-03-28 Amakem Nv Novel soft rock inhibitors
CA2850350A1 (en) 2011-09-30 2013-04-04 Ipsen Pharma S.A.S. Macrocyclic lrrk2 kinase inhibitors
WO2013045653A1 (en) 2011-09-30 2013-04-04 Oncodesign S.A. Macrocyclic flt3 kinase inhibitors
ES2958619T3 (es) 2012-01-30 2024-02-12 Univ Gent Compuestos anti-invasivos
GB201204756D0 (en) 2012-03-19 2012-05-02 Lewi Paulus J Triazines with suitable spacers for treatment and/or prevention of HIV infections
WO2014072419A1 (en) 2012-11-08 2014-05-15 Universiteit Antwerpen Novel anti-hiv compounds
WO2014140313A1 (en) 2013-03-15 2014-09-18 Oncodesign S.A. Macrocyclic salt-inducible kinase inhibitors
US9427376B2 (en) * 2013-10-10 2016-08-30 Chiesi Farmaceutici S.P.A. Process for preparing pharmaceutical formulations for inhalation comprising a high-dosage strength active ingredient
WO2015150337A1 (en) 2014-04-01 2015-10-08 Amakem Nv Lim kinase inhibitors
WO2016003450A1 (en) 2014-07-01 2016-01-07 The Regents Of The University Of California Pkc-epsilon inhibitors
EP3166955B1 (de) 2014-07-08 2018-05-02 Universiteit Gent Hamamelitanninanaloga und verwendungen davon
DK3194407T3 (da) 2014-09-17 2020-01-27 Oncodesign Sa Makrocykliske RIP2-kinaseinhibitorer
MX2017003470A (es) 2014-09-17 2017-08-07 Oncodesign Sa Inhibidores macrociclicos de cinasa lrrk2.
WO2016083490A1 (en) 2014-11-27 2016-06-02 Remynd Nv Compounds for the treatment of amyloid-associated diseases
WO2016146651A1 (en) 2015-03-16 2016-09-22 Oncodesign Sa Macrocyclic activin-like receptor kinase inhibitors
WO2017146994A1 (en) * 2016-02-24 2017-08-31 Merck Sharp & Dohme Corp. Controlled agglomeration of micronized drug or drug-excipient mixtures
WO2017157882A1 (en) 2016-03-14 2017-09-21 Université Catholique de Louvain Serine biosynthetic pathway inhibitors
WO2018065387A1 (en) 2016-10-04 2018-04-12 Universiteit Gent Novel hamamelitannin analogues and uses thereof
EP3544952A1 (de) 2016-11-24 2019-10-02 Universiteit Antwerpen Halogenierte benzotropolone als atg4b-inhibitoren
US20190388426A1 (en) 2017-01-30 2019-12-26 Université de Liège Perk and ire-1a inhibitors against neurodevelopmental disorders
US11548881B2 (en) 2017-05-11 2023-01-10 Remynd N.V. Compounds for the treatment of epilepsy, neurodegenerative disorders and other CNS disorders
US20210145838A1 (en) 2018-04-05 2021-05-20 Universiteit Hasselt Selective pde4d inhibitors against demyelinating diseases
WO2020047229A1 (en) 2018-08-29 2020-03-05 University Of Massachusetts Inhibition of protein kinases to treat friedreich ataxia
WO2020229595A1 (en) 2019-05-14 2020-11-19 Molecular Targeted Radiopharmaceuticals Holding Gmbh (Mtr) Quinazoline-2,4-dione derivatives as parp inhibitors
WO2022157381A1 (en) 2021-01-25 2022-07-28 Universiteit Hasselt Phloretin for use in the treatment of neurodegenerative and demyelinating diseases
WO2023021132A1 (en) 2021-08-18 2023-02-23 Katholieke Universiteit Leuven 6-substituted- and 6,7-disubstituted-7-deazapurine ribonucleoside analogues
WO2023046900A1 (en) 2021-09-23 2023-03-30 Katholieke Universiteit Leuven Ribonucleoside analogues against -sars-cov-2
WO2023241799A1 (en) 2022-06-15 2023-12-21 Université Libre de Bruxelles Flavanols for use in the treatment of retroviral infections

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2609150A (en) * 1949-11-05 1952-09-02 Union Carbide & Carbon Corp Mechanical pulverization of refrigerated plastics
NL128302C (de) * 1960-03-25 1900-01-01
GB1242211A (en) * 1967-08-08 1971-08-11 Fisons Pharmaceuticals Ltd Pharmaceutical composition
US3802822A (en) * 1972-03-01 1974-04-09 Mars Mineral Corp Pelletizer
GB1569611A (en) * 1976-01-23 1980-06-18 Fisons Ltd Pelletised or granular medicament formulation
GB1520247A (en) * 1974-08-10 1978-08-02 Fisons Ltd Pelletised medicament formulations
US4161516A (en) * 1975-07-25 1979-07-17 Fisons Limited Composition for treating airway disease
US4161526A (en) * 1978-07-20 1979-07-17 Sterling Drug Inc. Zinc salt prevention or removal of discoloration in pyrithione, pyrithione salt and dipyrithione compositions
DE3268533D1 (en) * 1981-07-24 1986-02-27 Fisons Plc Inhalation drugs, methods for their production and pharmaceutical formulations containing them
US4688610A (en) * 1985-03-19 1987-08-25 Spiral Systems Inc. Apparatus for dispensing particulate agglomerating solids
US4940556A (en) * 1986-01-30 1990-07-10 Syntex (U.S.A.) Inc. Method of preparing long acting formulation
GB8606762D0 (en) * 1986-03-19 1986-04-23 Boots Co Plc Therapeutic agents
JPS63116732A (ja) * 1986-11-06 1988-05-21 Fukae Kogyo Kk 粉粒体処理装置
GB8711005D0 (en) * 1987-05-09 1987-06-10 British Petroleum Co Plc Chemical process
DE59100388D1 (de) * 1990-01-29 1993-10-28 Ciba Geigy Verfahren und Vorrichtung zur Dosierung eines feinkörnigen Pulvers.
GB9027018D0 (en) * 1990-12-12 1991-01-30 Ici Plc Heterocyclic compounds
US5394868A (en) * 1992-06-25 1995-03-07 Schering Corporation Inhalation device for powdered medicaments

Also Published As

Publication number Publication date
EP0721331B1 (de) 2001-12-05
HUT74519A (en) 1997-01-28
AU679789B2 (en) 1997-07-10
AU7826194A (en) 1995-05-01
DK0721331T3 (da) 2002-02-11
FI961430A0 (fi) 1996-03-29
CZ289214B6 (cs) 2001-12-12
FI116364B (fi) 2005-11-15
ES2166786T3 (es) 2002-05-01
CN1132476A (zh) 1996-10-02
SG48049A1 (en) 1998-04-17
DE69429357D1 (de) 2002-01-17
HU9600821D0 (en) 1996-05-28
BR9407686A (pt) 1997-02-04
DE69429357T2 (de) 2002-08-14
RU2170082C2 (ru) 2001-07-10
SK39196A3 (en) 1997-06-04
EG20677A (en) 1999-11-30
NO961290L (no) 1996-03-29
NO961290D0 (no) 1996-03-29
NO314836B1 (no) 2003-06-02
WO1995009615A1 (en) 1995-04-13
HU222355B1 (hu) 2003-06-28
ATE209903T1 (de) 2001-12-15
PT721331E (pt) 2002-05-31
PL313765A1 (en) 1996-07-22
CZ94296A3 (en) 1996-06-12
EP0721331A1 (de) 1996-07-17
JP3732508B2 (ja) 2006-01-05
PL175564B1 (pl) 1999-01-29
CN1110300C (zh) 2003-06-04
FI961430A (fi) 1996-03-29
US5551489A (en) 1996-09-03
NZ274277A (en) 1998-01-26
IL111080A0 (en) 1994-11-28
JPH09504224A (ja) 1997-04-28
IL111080A (en) 1999-08-17

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Expiry date: 20140929