NO310022B1 - Kinoksalinforbindelser, deres anvendelse, samt farmasöytiske preparater - Google Patents
Kinoksalinforbindelser, deres anvendelse, samt farmasöytiske preparater Download PDFInfo
- Publication number
- NO310022B1 NO310022B1 NO944942A NO944942A NO310022B1 NO 310022 B1 NO310022 B1 NO 310022B1 NO 944942 A NO944942 A NO 944942A NO 944942 A NO944942 A NO 944942A NO 310022 B1 NO310022 B1 NO 310022B1
- Authority
- NO
- Norway
- Prior art keywords
- dihydroquinoxaline
- dione
- nitro
- chloro
- trifluoromethyl
- Prior art date
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Classifications
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- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
- C07D241/40—Benzopyrazines
- C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/50—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to ring nitrogen atoms
- C07D241/52—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/50—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to ring nitrogen atoms
- C07D241/54—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
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US90308092A | 1992-06-22 | 1992-06-22 | |
US99516792A | 1992-12-22 | 1992-12-22 | |
US6927493A | 1993-05-28 | 1993-05-28 | |
PCT/US1993/005859 WO1994000124A1 (en) | 1992-06-22 | 1993-06-17 | Glycine receptor antagonists and the use thereof |
Publications (3)
Publication Number | Publication Date |
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NO944942D0 NO944942D0 (no) | 1994-12-20 |
NO944942L NO944942L (no) | 1995-02-22 |
NO310022B1 true NO310022B1 (no) | 2001-05-07 |
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Family Applications (1)
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NO944942A NO310022B1 (no) | 1992-06-22 | 1994-12-20 | Kinoksalinforbindelser, deres anvendelse, samt farmasöytiske preparater |
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US (3) | US5514680A (de) |
EP (1) | EP0647137B1 (de) |
JP (1) | JP3301024B2 (de) |
KR (1) | KR100304017B1 (de) |
AT (1) | ATE404201T1 (de) |
AU (1) | AU672617B2 (de) |
CA (1) | CA2138026C (de) |
DE (1) | DE69334237D1 (de) |
DK (1) | DK0647137T3 (de) |
ES (1) | ES2313714T3 (de) |
FI (1) | FI120094B (de) |
NO (1) | NO310022B1 (de) |
NZ (1) | NZ254404A (de) |
PT (1) | PT647137E (de) |
WO (1) | WO1994000124A1 (de) |
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DK73091D0 (da) * | 1991-04-22 | 1991-04-22 | Novo Nordisk As | Quinoxalinforbindelser, deres fremstilling og anvendelse |
US5196421A (en) * | 1991-06-05 | 1993-03-23 | Eli Lilly And Company | Excitatory amino acid receptor antagonists in methods for the use thereof |
PT101004B (pt) * | 1991-10-26 | 1999-10-29 | Schering Ag | Derivados da quinoxalina, processo para a sua preparacao e composicoes farmaceuticas que os contem |
DE4217952A1 (de) * | 1992-05-30 | 1993-12-02 | Basf Ag | Chinoxalin-2,3(1H,4H)-dione |
CA2098446A1 (en) * | 1992-09-30 | 1994-03-31 | Eckard Weber | 2,5-dihydro-2,5-dioxo-1h-azepines and 2,5-dihydro-2-oxo-1h-azepines and the use thereof as excitatory amino acid and glycine receptor antagonists |
US5352683A (en) * | 1993-03-05 | 1994-10-04 | Virginia Commonwealth University Medical College Of Virginia | Method for the treatment of chronic pain |
IL109397A0 (en) * | 1993-04-28 | 1994-07-31 | Schering Ag | Quinoxalinedione derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same |
-
1993
- 1993-06-17 PT PT93916620T patent/PT647137E/pt unknown
- 1993-06-17 AT AT93916620T patent/ATE404201T1/de active
- 1993-06-17 AU AU46412/93A patent/AU672617B2/en not_active Ceased
- 1993-06-17 CA CA002138026A patent/CA2138026C/en not_active Expired - Lifetime
- 1993-06-17 KR KR1019940704688A patent/KR100304017B1/ko not_active IP Right Cessation
- 1993-06-17 WO PCT/US1993/005859 patent/WO1994000124A1/en active Application Filing
- 1993-06-17 NZ NZ254404A patent/NZ254404A/xx not_active IP Right Cessation
- 1993-06-17 ES ES93916620T patent/ES2313714T3/es not_active Expired - Lifetime
- 1993-06-17 DE DE69334237T patent/DE69334237D1/de not_active Expired - Lifetime
- 1993-06-17 DK DK93916620T patent/DK0647137T3/da active
- 1993-06-17 JP JP50247594A patent/JP3301024B2/ja not_active Expired - Fee Related
- 1993-06-17 EP EP93916620A patent/EP0647137B1/de not_active Expired - Lifetime
- 1993-11-05 US US08/148,259 patent/US5514680A/en not_active Expired - Lifetime
-
1994
- 1994-12-20 NO NO944942A patent/NO310022B1/no not_active IP Right Cessation
- 1994-12-21 FI FI946005A patent/FI120094B/fi not_active IP Right Cessation
-
1995
- 1995-03-17 US US08/405,708 patent/US5620979A/en not_active Expired - Lifetime
- 1995-03-17 US US08/405,713 patent/US5622952A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
PT647137E (pt) | 2008-11-24 |
NZ254404A (en) | 1997-08-22 |
FI946005A0 (fi) | 1994-12-21 |
ATE404201T1 (de) | 2008-08-15 |
AU4641293A (en) | 1994-01-24 |
AU672617B2 (en) | 1996-10-10 |
EP0647137A4 (de) | 1998-09-16 |
US5514680A (en) | 1996-05-07 |
FI946005A (fi) | 1995-02-21 |
EP0647137B1 (de) | 2008-08-13 |
FI120094B (fi) | 2009-06-30 |
ES2313714T3 (es) | 2009-03-01 |
CA2138026A1 (en) | 1994-01-06 |
US5622952A (en) | 1997-04-22 |
CA2138026C (en) | 2003-09-09 |
JPH08501283A (ja) | 1996-02-13 |
KR100304017B1 (ko) | 2001-11-22 |
NO944942L (no) | 1995-02-22 |
WO1994000124A1 (en) | 1994-01-06 |
DE69334237D1 (de) | 2008-09-25 |
EP0647137A1 (de) | 1995-04-12 |
JP3301024B2 (ja) | 2002-07-15 |
NO944942D0 (no) | 1994-12-20 |
DK0647137T3 (da) | 2008-12-08 |
US5620979A (en) | 1997-04-15 |
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MM1K | Lapsed by not paying the annual fees |