AU9049391A - 2-acylamido derivatives of 3,4-dihydro-3-oxo-quinoxaline having pharmaceutical activity - Google Patents

2-acylamido derivatives of 3,4-dihydro-3-oxo-quinoxaline having pharmaceutical activity

Info

Publication number
AU9049391A
AU9049391A AU90493/91A AU9049391A AU9049391A AU 9049391 A AU9049391 A AU 9049391A AU 90493/91 A AU90493/91 A AU 90493/91A AU 9049391 A AU9049391 A AU 9049391A AU 9049391 A AU9049391 A AU 9049391A
Authority
AU
Australia
Prior art keywords
quinoxaline
dihydro
oxo
pharmaceutical activity
acylamido
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU90493/91A
Inventor
Sheryl Jeanne Hays
Graham Johnson
Leonard Joseph Lescosky
Thomas Charles Malone
Perry Michael Novak
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Lambert Co LLC
Original Assignee
Warner Lambert Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co LLC filed Critical Warner Lambert Co LLC
Publication of AU9049391A publication Critical patent/AU9049391A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
    • C07C233/15—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/32—Oximes
    • C07C251/34—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C251/36—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with the carbon atoms of the oxyimino groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C251/38—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with the carbon atoms of the oxyimino groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of a saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/40—Benzopyrazines
    • C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
AU90493/91A 1990-12-20 1991-11-22 2-acylamido derivatives of 3,4-dihydro-3-oxo-quinoxaline having pharmaceutical activity Abandoned AU9049391A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63113990A 1990-12-20 1990-12-20
US631139 2000-08-02

Publications (1)

Publication Number Publication Date
AU9049391A true AU9049391A (en) 1992-07-22

Family

ID=24529936

Family Applications (1)

Application Number Title Priority Date Filing Date
AU90493/91A Abandoned AU9049391A (en) 1990-12-20 1991-11-22 2-acylamido derivatives of 3,4-dihydro-3-oxo-quinoxaline having pharmaceutical activity

Country Status (6)

Country Link
AU (1) AU9049391A (en)
IE (1) IE914452A1 (en)
MX (1) MX9102701A (en)
PT (1) PT99899A (en)
WO (1) WO1992011245A1 (en)
ZA (1) ZA9110018B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU674613B2 (en) * 1993-09-28 1997-01-02 Otsuka Pharmaceutical Co., Ltd. Quinoxaline derivative as antidiabetic agent

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT647137E (en) * 1992-06-22 2008-11-24 Univ California Glycine receptor antagonists and the use thereof
FR2707643B1 (en) * 1993-07-16 1995-08-11 Rhone Poulenc Rorer Sa Imidazo [1,2-a] pyrazine-4-one derivatives, their preparation and drugs containing them.
US5631373A (en) 1993-11-05 1997-05-20 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon, Eugene Oregon Alkyl, azido, alkoxy, and fluoro-substituted and fused quinoxalinediones
US5801183A (en) * 1995-01-27 1998-09-01 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon Aza and aza (N-oxy) analogs of glycine/NMDA receptor antagonists
WO1999011632A1 (en) * 1997-09-01 1999-03-11 Kyorin Pharmaceutical Co., Ltd. 6,7-asymmetrically disubstituted quinoxalinecarboxylic acid deri vatives, addition salts thereof, and processes for the preparation of both
EA200001247A1 (en) 1998-06-03 2001-08-27 Джи Пи Ай Нил Холдингс, Инк. N-BONDED SULPHONAMIDES OF N-HETEROCYCLIC CARBONIC ACIDS OR ISATERES OF CARBONIC ACIDS
JP2000309586A (en) 1999-02-26 2000-11-07 Kyorin Pharmaceut Co Ltd 6-substituted-7-heteroquinoxalinecarboxylic acid derivative, its addition salt and production thereof
US7253169B2 (en) 1999-11-12 2007-08-07 Gliamed, Inc. Aza compounds, pharmaceutical compositions and methods of use
US6417189B1 (en) 1999-11-12 2002-07-09 Gpi Nil Holdings, Inc. AZA compounds, pharmaceutical compositions and methods of use
CA2393466C (en) 1999-12-21 2010-01-19 Gpi Nil Holdings, Inc. Hydantoin derivative compounds, pharmaceutical compositions, and methods of using same
FR2827599A1 (en) * 2001-07-20 2003-01-24 Neuro3D Treating central nervous system disorders, e.g. anxiety, depression, schizophrenia or pain, using new or known 2-substituted quinoline or quinoxaline derivatives having xanthenuric acid modulating action
DE10153345A1 (en) * 2001-10-29 2003-05-08 Gruenenthal Gmbh Substituted 1H-quinoxalin-2-one compounds and substituted 4-aryl and 4-heteroarylcyclohexane compounds
SE0302324D0 (en) * 2003-08-28 2003-08-28 Astrazeneca Ab Novel compounds
JP2007513184A (en) * 2003-12-04 2007-05-24 バーテックス　ファーマシューティカルズ　インコーポレイテッド Quinoxaline useful as an inhibitor of protein kinase
WO2009070644A1 (en) * 2007-11-30 2009-06-04 Smithkline Beecham Corporation Prolyl hydroxylase inhibitors
WO2009073497A2 (en) * 2007-11-30 2009-06-11 Smithkline Beecham Corporation Prolyl hydroxylase inhibitors
US8889683B2 (en) * 2010-09-27 2014-11-18 Merck Sharp & Dohme Corp. Substituted quinoxalines as inhibitors of fatty acid binding protein
RU2744429C1 (en) * 2020-05-02 2021-03-09 Андрей Александрович Иващенко Anti-rna viral, including anti-coronavirus agent - substituted quinoxaline, pharmaceutical composition and applications

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0008864A1 (en) * 1978-08-15 1980-03-19 FISONS plc Pyridopyrazine and quinoxaline derivatives, processes for their preparation, and pharmaceutical compositions containing them
GR72941B (en) * 1978-10-20 1984-01-16 Lilly Co Eli
US4252954A (en) * 1979-10-25 1981-02-24 Eli Lilly And Company Salts of dihalo-3,4-dihydro-3-oxo-2-quinoxaline carboxylic acids and hindered amines

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU674613B2 (en) * 1993-09-28 1997-01-02 Otsuka Pharmaceutical Co., Ltd. Quinoxaline derivative as antidiabetic agent

Also Published As

Publication number Publication date
IE914452A1 (en) 1992-07-01
WO1992011245A1 (en) 1992-07-09
PT99899A (en) 1993-01-29
MX9102701A (en) 1992-06-01
ZA9110018B (en) 1993-06-21

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