NO20012175D0 - Fremgangsmåte for fremstilling av suspensjoner av legemiddelpartikler for inhalering - Google Patents

Fremgangsmåte for fremstilling av suspensjoner av legemiddelpartikler for inhalering

Info

Publication number
NO20012175D0
NO20012175D0 NO20012175A NO20012175A NO20012175D0 NO 20012175 D0 NO20012175 D0 NO 20012175D0 NO 20012175 A NO20012175 A NO 20012175A NO 20012175 A NO20012175 A NO 20012175A NO 20012175 D0 NO20012175 D0 NO 20012175D0
Authority
NO
Norway
Prior art keywords
inhalation
suspensions
drug particle
particle suspensions
directed
Prior art date
Application number
NO20012175A
Other languages
English (en)
Other versions
NO20012175L (no
Inventor
Eva Bernini
Raffaella Carzia
Paolo Chiesi
Chiara Malvolti
Gaetano Brambilla
Original Assignee
Chiesi Farma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa
Publication of NO20012175D0 publication Critical patent/NO20012175D0/no
Publication of NO20012175L publication Critical patent/NO20012175L/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/12Aerosols; Foams
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/902Specified use of nanostructure
    • Y10S977/904Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/902Specified use of nanostructure
    • Y10S977/904Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/906Drug delivery
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/902Specified use of nanostructure
    • Y10S977/904Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/926Topical chemical, e.g. cosmetic or sunscreen

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Pulmonology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Otolaryngology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
NO20012175A 1998-11-03 2001-05-02 Fremgangsmåte for fremstilling av suspensjoner av legemiddelpartikler for inhalering NO20012175L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1998MI002364A IT1303692B1 (it) 1998-11-03 1998-11-03 Procedimento per la preparazione di sospensioni di particelle difarmaci da somministrare per inalazione.
PCT/EP1999/008176 WO2000025746A2 (en) 1998-11-03 1999-10-28 A process for the preparation of suspensions of drug particles for inhalation delivery

Publications (2)

Publication Number Publication Date
NO20012175D0 true NO20012175D0 (no) 2001-05-02
NO20012175L NO20012175L (no) 2001-07-02

Family

ID=11380994

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20012175A NO20012175L (no) 1998-11-03 2001-05-02 Fremgangsmåte for fremstilling av suspensjoner av legemiddelpartikler for inhalering

Country Status (26)

Country Link
US (1) US6464958B1 (no)
EP (2) EP1832279B1 (no)
JP (1) JP2002528484A (no)
KR (1) KR100783096B1 (no)
CN (1) CN1158997C (no)
AT (1) ATE352288T1 (no)
AU (1) AU762367B2 (no)
BR (2) BRPI9917701B1 (no)
CA (2) CA2349268C (no)
CY (2) CY1107659T1 (no)
CZ (2) CZ306939B6 (no)
DE (1) DE69935002T2 (no)
DK (2) DK1832279T3 (no)
EA (1) EA003228B1 (no)
ES (1) ES2281197T3 (no)
HU (2) HU230121B1 (no)
IT (1) IT1303692B1 (no)
NO (1) NO20012175L (no)
NZ (1) NZ511305A (no)
PL (1) PL195908B1 (no)
PT (1) PT1126823E (no)
SI (1) SI1126823T1 (no)
SK (2) SK288316B6 (no)
TR (1) TR200101209T2 (no)
WO (1) WO2000025746A2 (no)
ZA (1) ZA200103526B (no)

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PT1126826E (pt) 1998-11-02 2008-11-25 Elan Pharma Int Ltd Composição de metilfenidato de libertação modificada multiparticulada
AUPQ573300A0 (en) * 2000-02-21 2000-03-16 Australian Nuclear Science & Technology Organisation Controlled release ceramic particles, compositions thereof, processes of preparation and methods of use
NZ523693A (en) * 2000-07-10 2004-08-27 Chiron Corp Macrolide formulations for inhalation and methods of treatment of endobronchial infections
SG98420A1 (en) * 2000-07-13 2003-09-19 Purzer Pharmaceutical Co Ltd Method for transferring one or more active ingredients between different phase carriers
US6667344B2 (en) 2001-04-17 2003-12-23 Dey, L.P. Bronchodilating compositions and methods
US20030091513A1 (en) * 2001-10-03 2003-05-15 Mohsen Nahed M. Method to generate water soluble or nonwater soluble in nanoparticulates directly in suspension or dispersion media
US20030129242A1 (en) * 2002-01-04 2003-07-10 Bosch H. William Sterile filtered nanoparticulate formulations of budesonide and beclomethasone having tyloxapol as a surface stabilizer
WO2003070285A1 (en) 2002-02-19 2003-08-28 Resolution Chemicals Limited Solvent-based sterilisation of pharmaceuticals
ITMI20020808A1 (it) * 2002-04-17 2003-10-17 Chiesi Farma Spa Procedimento per la preparazione di una sospensione sterile di particelle di beclometasone dipropionato da somministrare per inalazione
WO2004032980A1 (en) * 2002-10-04 2004-04-22 Elan Pharma International Limited Gamma irradiation of solid nanoparticulate active agents
ITMI20022674A1 (it) * 2002-12-18 2004-06-19 Chiesi Farma Spa Procedimento per la preparazione di formulazioni sterili a base di principi attivi farmaceutici cristallini micronizzati da somministrare come sospensioni acquose per inalazione.
US20040208833A1 (en) * 2003-02-04 2004-10-21 Elan Pharma International Ltd. Novel fluticasone formulations
WO2004073685A1 (en) * 2003-02-20 2004-09-02 Constant Research & Development Limited Dexamethasone-containing formulations for oral administration as well the process for manufacturing required therefor
EP1454636A1 (en) * 2003-03-04 2004-09-08 Dompé S.P.A. Sterilization of glucocorticoid drug particles for pulmonary delivery
US9808471B2 (en) * 2003-04-16 2017-11-07 Mylan Specialty Lp Nasal pharmaceutical formulations and methods of using the same
US7811606B2 (en) * 2003-04-16 2010-10-12 Dey, L.P. Nasal pharmaceutical formulations and methods of using the same
US8912174B2 (en) 2003-04-16 2014-12-16 Mylan Pharmaceuticals Inc. Formulations and methods for treating rhinosinusitis
EP1626742A1 (en) * 2003-05-22 2006-02-22 Elan Pharma International Limited Sterilization of dispersions of nanoparticulate active agents with gamma radiation
TWI359675B (en) 2003-07-10 2012-03-11 Dey L P Bronchodilating β-agonist compositions
GB0319500D0 (en) * 2003-08-19 2003-09-17 Resolution Chemicals Ltd Particle-size reduction apparatus,and use thereof
ITMI20032054A1 (it) * 2003-10-22 2005-04-23 Monteres S R L Processo per la preparazione di sospensioni farmaceutiche da inalare.
RU2006121347A (ru) * 2003-11-18 2008-01-10 Янсонг ШЭН (US) Устройство для вдыхания, оказывающее благотворное влияние
PE20050941A1 (es) 2003-12-16 2005-11-08 Nycomed Gmbh Suspensiones acuosas de ciclesonida para nebulizacion
EP1574222B1 (en) * 2004-03-12 2011-02-09 Cipla Ltd. Sterilization process for steroids
WO2005089718A2 (en) 2004-03-23 2005-09-29 Novartis Ag Pharmaceutical compositions
GB0406515D0 (en) * 2004-03-23 2004-04-28 Novartis Ag Organic compounds
ITMI20040795A1 (it) * 2004-04-23 2004-07-23 Eratech S R L Composizione farmaceutica solida secca suo processo di preparazione e sospensione acquosa stabile ottenuta dalla stessa
GB0410995D0 (en) 2004-05-17 2004-06-23 Norton Healthcare Ltd Heat sterilization of glucocorticosteroids
GB0425266D0 (en) * 2004-11-16 2004-12-15 Norton Healthcare Ltd Pharmaceutical manufacturing process
CN101106972A (zh) * 2004-11-16 2008-01-16 伊兰制药国际有限公司 注射用纳米微粒奥氮平制剂
GB0427568D0 (en) * 2004-12-16 2005-01-19 Resolution Chemicals Ltd Particle-size reduction apparatus, and the use thereof
ES2388287T3 (es) 2005-01-20 2012-10-11 Eratech S.R.L. Procedimiento para la preparación de suspensiones concentradas de fármacos y kit correspondiente
WO2007062685A1 (en) 2005-11-29 2007-06-07 Farmabios S.P.A. Process for the preparation of micronised sterile steroids
US20080317843A1 (en) * 2006-07-12 2008-12-25 Elan Corporation Plc Nanoparticulate formulations of modafinil
RU2496479C2 (ru) * 2007-12-13 2013-10-27 Новартис Аг Органические соединения
MX2011012531A (es) * 2009-05-25 2011-12-16 Chiesi Farma Spa Combinacion terapeutica que comprende un tensioactivo pulmonar y un esteroide.
BR112013027391A2 (pt) 2011-05-03 2017-01-17 Chiesi Farmaceutic S P A formulação farmacêutica, frasco e kit
DK2704687T3 (en) 2011-05-04 2015-10-05 Chiesi Farma Spa Topical formulation having a corticosteroid as an active ingredient
CN104739811A (zh) * 2015-02-27 2015-07-01 上海臣邦医药科技有限公司 一种糖皮质激素雾化吸入混悬液及其制备方法
TWI773641B (zh) * 2015-05-08 2022-08-11 日商活效製藥股份有限公司 含有糖皮質類固醇(glucocorticoids)之奈米微粒子之水性懸浮液劑
WO2023136787A1 (en) * 2022-01-17 2023-07-20 Arven Ilac Sanayi Ve Ticaret Anonim Sirketi Process for the preparation of a sterile, homogeneous suspension for inhalation by nebulization

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DE69002718T2 (de) * 1989-09-08 1993-12-23 Glaxo Group Ltd Medikamente.
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JPH0486921A (ja) * 1990-07-31 1992-03-19 Omron Corp 近似推論のための知識ベース形成方法および装置
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UY24147A1 (es) * 1995-01-20 1996-02-02 Gruenenthal Chemie Procedimiento y dispositivo para preparar composiciones dispersables por aspersion de aerosoles
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IT1286496B1 (it) 1996-11-20 1998-07-15 Leetrim Ltd Dublin Composizione farmaceutica orale ad attivita' antipiretica,analgesica ed antiinfiammatoria
SE9704186D0 (sv) 1997-11-14 1997-11-14 Astra Ab New composition of matter

Also Published As

Publication number Publication date
SK288316B6 (sk) 2015-11-03
DE69935002T2 (de) 2007-07-19
EP1832279A3 (en) 2008-03-05
CZ20011541A3 (cs) 2001-09-12
CN1158997C (zh) 2004-07-28
BR9915251A (pt) 2001-10-30
CA2349268A1 (en) 2000-05-11
DK1832279T3 (en) 2015-10-05
CY1107659T1 (el) 2013-04-18
BRPI9917701B1 (pt) 2016-07-19
BRPI9915251B1 (pt) 2015-09-01
WO2000025746A2 (en) 2000-05-11
CA2614633A1 (en) 2000-05-11
DE69935002D1 (de) 2007-03-15
EP1126823A2 (en) 2001-08-29
HUP0104230A3 (en) 2006-07-28
HUP0104230A2 (hu) 2002-03-28
BRPI9915251B8 (pt) 2021-05-25
EP1832279B1 (en) 2015-07-01
CZ300650B6 (cs) 2009-07-08
AU1266600A (en) 2000-05-22
HU226734B1 (en) 2009-08-28
ITMI982364A1 (it) 2000-05-03
KR20010075656A (ko) 2001-08-09
WO2000025746A3 (en) 2000-10-26
PL195908B1 (pl) 2007-11-30
NZ511305A (en) 2003-07-25
HU0700446D0 (en) 2007-08-28
SK285487B6 (sk) 2007-02-01
KR100783096B1 (ko) 2007-12-07
DK1126823T3 (da) 2007-05-21
SI1126823T1 (sl) 2007-04-30
ES2281197T3 (es) 2007-09-16
HU230121B1 (hu) 2015-08-28
PL347908A1 (en) 2002-04-22
AU762367B2 (en) 2003-06-26
ATE352288T1 (de) 2007-02-15
CZ2007211A3 (cs) 2017-09-27
CA2349268C (en) 2009-03-31
CN1335766A (zh) 2002-02-13
CY1116943T1 (el) 2017-04-05
IT1303692B1 (it) 2001-02-23
SK5932001A3 (en) 2001-11-06
CZ306939B6 (cs) 2017-09-27
NO20012175L (no) 2001-07-02
ZA200103526B (en) 2002-06-03
JP2002528484A (ja) 2002-09-03
EA200100397A1 (ru) 2001-10-22
TR200101209T2 (tr) 2001-09-21
EP1126823B1 (en) 2007-01-24
EP1832279A2 (en) 2007-09-12
PT1126823E (pt) 2007-04-30
US6464958B1 (en) 2002-10-15
EA003228B1 (ru) 2003-02-27
CA2614633C (en) 2010-12-21

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