HUP0102892A2 - Erősen tömörített szilárd gyógyszerkészletet tartalmazó hatóanyag-leadó rendszer, eljárás az előállítására és alkalmazására - Google Patents
Erősen tömörített szilárd gyógyszerkészletet tartalmazó hatóanyag-leadó rendszer, eljárás az előállítására és alkalmazásáraInfo
- Publication number
- HUP0102892A2 HUP0102892A2 HU0102892A HUP0102892A HUP0102892A2 HU P0102892 A2 HUP0102892 A2 HU P0102892A2 HU 0102892 A HU0102892 A HU 0102892A HU P0102892 A HUP0102892 A HU P0102892A HU P0102892 A2 HUP0102892 A2 HU P0102892A2
- Authority
- HU
- Hungary
- Prior art keywords
- delivery system
- active ingredient
- subject
- preparation
- drug delivery
- Prior art date
Links
- 239000007787 solid Substances 0.000 title abstract 5
- 239000003814 drug Substances 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 238000012377 drug delivery Methods 0.000 title 1
- 239000004480 active ingredient Substances 0.000 abstract 4
- 239000013543 active substance Substances 0.000 abstract 2
- 239000002502 liposome Substances 0.000 abstract 2
- 239000002245 particle Substances 0.000 abstract 2
- 208000023504 respiratory system disease Diseases 0.000 abstract 2
- 238000007664 blowing Methods 0.000 abstract 1
- 208000037765 diseases and disorders Diseases 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 238000001415 gene therapy Methods 0.000 abstract 1
- 238000002649 immunization Methods 0.000 abstract 1
- 230000003053 immunization Effects 0.000 abstract 1
- 238000000462 isostatic pressing Methods 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 210000000056 organ Anatomy 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/04—Drugs for disorders of the respiratory system for throat disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
A találmány tárgya egy hatóanyag-leadó rendszer, amely egy alapvetőenizotróp szilárd halmazállapottal rendelkező, hatóanyagot tartalmazó,erősen tömörített gyógyszerkészletet tartalmaz, amely a hatóanyagottartalmazó belélegezhető részecskék létrehozására alkalmas, ahol azerősen tömörített szilárd gyógyszerkészlet legalább egy hatóanyagotliposzómákkal vagy egy hasonló szemcsés hordozóval asszociáltantartalmaz. A találmány tárgya továbbá egy eljárás a találmány szerintihatóanyag-leadó rendszer erősen tömörített szilárdgyógyszerkészletének előállítására, amely során a liposzómákat ismertmódon állítják elő vagy töltik meg, adott esetben legalább egysegédanyaggal keverik, majd ezt követően izosztatikus sajtolássalformatestté alakítják. Szintén a találmány tárgyát képezi egy erősentömörített szilárd gyógyszerkészlet alkalmazása a találmány szerintihatóanyag-leadó rendszerben olyan részecskék létrehozására, amelyekátfúvással és/vagy belégzéssel adagolhatók a légúti betegségek ésrendellenességek, valamint szervek betegségeinek ésrendellenességeinek terápiájában, génterápiában és/vagy immunizálásesetében. Ó
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8689598P | 1998-05-27 | 1998-05-27 | |
PCT/EP1999/003680 WO1999061003A1 (en) | 1998-05-27 | 1999-05-27 | Drug delivery system comprising a tightly compacted solid medicament stock |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP0102892A2 true HUP0102892A2 (hu) | 2002-03-28 |
HUP0102892A3 HUP0102892A3 (en) | 2002-12-28 |
Family
ID=22201600
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0102337A HU226710B1 (en) | 1998-05-27 | 1999-05-27 | Preparations for the application of anti-inflammatory, especially antiseptic agents and/or agents promoting the healing of wounds, to the upper respiratory tract and/or the ear |
HU0102899A HU226729B1 (en) | 1998-05-27 | 1999-05-27 | Preparation for the application of antiseptic agents and/or agents promoting the healing of wounds to the lower respiratory tract |
HU0102892A HUP0102892A3 (en) | 1998-05-27 | 1999-05-27 | Drug delivery system comprising a tightly compacted solid medicament stock, process for its preparation and for its use |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0102337A HU226710B1 (en) | 1998-05-27 | 1999-05-27 | Preparations for the application of anti-inflammatory, especially antiseptic agents and/or agents promoting the healing of wounds, to the upper respiratory tract and/or the ear |
HU0102899A HU226729B1 (en) | 1998-05-27 | 1999-05-27 | Preparation for the application of antiseptic agents and/or agents promoting the healing of wounds to the lower respiratory tract |
Country Status (19)
Country | Link |
---|---|
US (2) | US20080038330A1 (hu) |
EP (3) | EP1079807B1 (hu) |
JP (3) | JP4741726B2 (hu) |
KR (3) | KR20010043820A (hu) |
CN (3) | CN1303276A (hu) |
AT (3) | ATE235895T1 (hu) |
AU (3) | AU759264B2 (hu) |
BR (3) | BR9911070A (hu) |
CA (3) | CA2332389C (hu) |
CY (1) | CY1105834T1 (hu) |
DE (6) | DE29923848U1 (hu) |
DK (2) | DK1079806T3 (hu) |
ES (2) | ES2260915T3 (hu) |
HK (2) | HK1035335A1 (hu) |
HU (3) | HU226710B1 (hu) |
IL (4) | IL139229A0 (hu) |
PT (2) | PT1079806E (hu) |
RU (3) | RU2202340C2 (hu) |
WO (3) | WO1999061003A1 (hu) |
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1999
- 1999-05-27 BR BR9911070-9A patent/BR9911070A/pt not_active IP Right Cessation
- 1999-05-27 DK DK99926446T patent/DK1079806T3/da active
- 1999-05-27 HU HU0102337A patent/HU226710B1/hu unknown
- 1999-05-27 RU RU2000131695/14A patent/RU2202340C2/ru not_active IP Right Cessation
- 1999-05-27 EP EP99926448A patent/EP1079807B1/en not_active Expired - Lifetime
- 1999-05-27 AT AT99953285T patent/ATE235895T1/de not_active IP Right Cessation
- 1999-05-27 IL IL13922999A patent/IL139229A0/xx unknown
- 1999-05-27 AU AU43704/99A patent/AU759264B2/en not_active Expired
- 1999-05-27 CA CA002332389A patent/CA2332389C/en not_active Expired - Lifetime
- 1999-05-27 EP EP99926446A patent/EP1079806B1/en not_active Expired - Lifetime
- 1999-05-27 JP JP2000550459A patent/JP4741726B2/ja not_active Expired - Fee Related
- 1999-05-27 IL IL13923199A patent/IL139231A0/xx not_active IP Right Cessation
- 1999-05-27 CN CN99806648A patent/CN1303276A/zh active Pending
- 1999-05-27 KR KR1020007013258A patent/KR20010043820A/ko not_active Application Discontinuation
- 1999-05-27 BR BR9911072-5A patent/BR9911072A/pt not_active Application Discontinuation
- 1999-05-27 DE DE29923848U patent/DE29923848U1/de not_active Expired - Lifetime
- 1999-05-27 DE DE69906518T patent/DE69906518D1/de not_active Expired - Lifetime
- 1999-05-27 WO PCT/EP1999/003680 patent/WO1999061003A1/en not_active Application Discontinuation
- 1999-05-27 HU HU0102899A patent/HU226729B1/hu unknown
- 1999-05-27 ES ES99926446T patent/ES2260915T3/es not_active Expired - Lifetime
- 1999-05-27 KR KR1020007013257A patent/KR100613706B1/ko not_active IP Right Cessation
- 1999-05-27 RU RU2000132711/14A patent/RU2211693C2/ru active
- 1999-05-27 BR BR9911071-7A patent/BR9911071A/pt not_active Application Discontinuation
- 1999-05-27 HU HU0102892A patent/HUP0102892A3/hu unknown
- 1999-05-27 AT AT99926448T patent/ATE339187T1/de active
- 1999-05-27 RU RU2000132713/14A patent/RU2212884C2/ru active
- 1999-05-27 JP JP2000550463A patent/JP2002516269A/ja active Pending
- 1999-05-27 DE DE69933208T patent/DE69933208T2/de not_active Expired - Lifetime
- 1999-05-27 CN CN99806578A patent/CN1303272A/zh active Pending
- 1999-05-27 PT PT99926446T patent/PT1079806E/pt unknown
- 1999-05-27 IL IL13923099A patent/IL139230A0/xx active IP Right Grant
- 1999-05-27 ES ES99926448T patent/ES2273493T3/es not_active Expired - Lifetime
- 1999-05-27 EP EP99953285A patent/EP1083886B1/en not_active Expired - Lifetime
- 1999-05-27 WO PCT/EP1999/003677 patent/WO1999060998A1/en active IP Right Grant
- 1999-05-27 AU AU42667/99A patent/AU747877B2/en not_active Ceased
- 1999-05-27 AT AT99926446T patent/ATE319427T1/de active
- 1999-05-27 KR KR10-2000-7013259A patent/KR100445146B1/ko not_active IP Right Cessation
- 1999-05-27 DK DK99926448T patent/DK1079807T3/da active
- 1999-05-27 JP JP2000550460A patent/JP4741727B2/ja not_active Expired - Fee Related
- 1999-05-27 DE DE29923766U patent/DE29923766U1/de not_active Expired - Lifetime
- 1999-05-27 DE DE29923847U patent/DE29923847U1/de not_active Expired - Lifetime
- 1999-05-27 CA CA002332369A patent/CA2332369A1/en not_active Abandoned
- 1999-05-27 AU AU43706/99A patent/AU752018C/en not_active Expired
- 1999-05-27 CN CN99806577A patent/CN1303271A/zh active Pending
- 1999-05-27 CA CA002332371A patent/CA2332371A1/en not_active Abandoned
- 1999-05-27 PT PT99926448T patent/PT1079807E/pt unknown
- 1999-05-27 WO PCT/EP1999/003681 patent/WO1999060999A1/en active IP Right Grant
- 1999-05-27 DE DE69930259T patent/DE69930259T2/de not_active Expired - Lifetime
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2000
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2001
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2006
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- 2007-10-11 US US11/974,419 patent/US20080038330A1/en not_active Abandoned
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