SG167657A1 - Novel medicament compositions based on tiotropium salts and on salmeterol salts - Google Patents

Novel medicament compositions based on tiotropium salts and on salmeterol salts

Info

Publication number
SG167657A1
SG167657A1 SG200505149-5A SG2005051495A SG167657A1 SG 167657 A1 SG167657 A1 SG 167657A1 SG 2005051495 A SG2005051495 A SG 2005051495A SG 167657 A1 SG167657 A1 SG 167657A1
Authority
SG
Singapore
Prior art keywords
salts
salmeterol
compositions based
tiotropium
medicament compositions
Prior art date
Application number
SG200505149-5A
Inventor
Nagel Juergen
Schmelzer Christel
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of SG167657A1 publication Critical patent/SG167657A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Abstract

The present invention relates to novel pharmaceutical compositions based on tiotropium salts and salts of salmeterol, processes for preparing them and their use in the treatment of respiratory diseases. No suitable figure
SG200505149-5A 2000-11-13 2001-11-09 Novel medicament compositions based on tiotropium salts and on salmeterol salts SG167657A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10056104A DE10056104A1 (en) 2000-11-13 2000-11-13 Drug compositions useful for treatment of respiratory diseases, especially asthma and chronic obstructive pulmonary disease comprises tiotropium salts and salmeterol salts

Publications (1)

Publication Number Publication Date
SG167657A1 true SG167657A1 (en) 2011-01-28

Family

ID=7663071

Family Applications (1)

Application Number Title Priority Date Filing Date
SG200505149-5A SG167657A1 (en) 2000-11-13 2001-11-09 Novel medicament compositions based on tiotropium salts and on salmeterol salts

Country Status (32)

Country Link
EP (3) EP1335728B1 (en)
JP (2) JP4282322B2 (en)
KR (2) KR100886094B1 (en)
CN (1) CN1678318A (en)
AT (2) ATE362761T1 (en)
AU (3) AU2002227910B2 (en)
BG (1) BG107781A (en)
BR (1) BR0115226A (en)
CA (1) CA2429012A1 (en)
CY (1) CY1106774T1 (en)
CZ (1) CZ20031444A3 (en)
DE (3) DE10056104A1 (en)
DK (2) DK1335728T3 (en)
EA (1) EA007904B1 (en)
EC (1) ECSP034571A (en)
EE (1) EE200300228A (en)
ES (2) ES2240549T3 (en)
HR (1) HRP20030378A2 (en)
HU (1) HUP0301447A3 (en)
IL (2) IL155718A0 (en)
MX (1) MXPA03004164A (en)
NO (1) NO20032111L (en)
NZ (1) NZ526400A (en)
PL (1) PL205330B1 (en)
PT (2) PT1514546E (en)
RS (2) RS50286B (en)
SG (1) SG167657A1 (en)
SI (2) SI1514546T1 (en)
SK (2) SK286950B6 (en)
UA (1) UA74853C2 (en)
WO (1) WO2002038154A1 (en)
ZA (1) ZA200302921B (en)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2165768B1 (en) 1999-07-14 2003-04-01 Almirall Prodesfarma Sa NEW DERIVATIVES OF QUINUCLIDINE AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM.
US7214687B2 (en) 1999-07-14 2007-05-08 Almirall Ag Quinuclidine derivatives and medicinal compositions containing the same
EP1523976A3 (en) * 1999-11-23 2005-06-22 Glaxo Group Limited Pharmaceutical formulations of salmeterol
MXPA04002401A (en) * 2001-09-14 2004-05-31 Boehringer Ingelheim Pharma Novel medicaments for inhalation.
DE10214263A1 (en) * 2002-03-28 2003-10-16 Boehringer Ingelheim Pharma HFA suspension formulations containing an anticholinergic
US7311894B2 (en) 2002-03-28 2007-12-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg HFA suspension formulations containing an anticholinergic
US7244415B2 (en) 2002-03-28 2007-07-17 Boehringer Ingelheim Pharma Gmbh & Co. Kg HFA suspension formulations of an anhydrate
US7250426B2 (en) 2002-11-29 2007-07-31 Boehringer Ingelheim Pharma Gmbh & Co Kg Tiotropium-containing pharmaceutical combination for inhalation
DE10256080A1 (en) * 2002-11-29 2004-06-17 Boehringer Ingelheim Pharma Gmbh & Co. Kg Combination medicinal product for inhalation containing tiotropium
CN1726038A (en) * 2002-12-16 2006-01-25 贝林格尔英格海姆法玛两合公司 Tiotropium containing HFC solution formulations
DE10351663A1 (en) * 2002-12-20 2004-07-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Stable, accurately dosable inhalable powder medicament for treating asthma or chronic obstructive pulmonary disease, containing tiotropium, specific form of salmeterol xinafoate and auxiliary
DE10345065A1 (en) * 2003-09-26 2005-04-14 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosol formulation for inhalation containing an anticholinergic
WO2005042526A1 (en) * 2003-11-03 2005-05-12 Boehringer Ingelheim International Gmbh Method for producing tiotropium salts, tiotropium salts and pharmaceutical formulations, containing the same
JP5165245B2 (en) * 2003-11-03 2013-03-21 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Novel tiotropium salt, process for its production and pharmaceutical composition containing tiotropium salt
ES2257152B1 (en) * 2004-05-31 2007-07-01 Laboratorios Almirall S.A. COMBINATIONS THAT INCLUDE ANTIMUSCARINIC AGENTS AND BETA-ADRENERGIC AGONISTS.
EP1761279A1 (en) * 2004-05-31 2007-03-14 Laboratorios Almirall, S.A. Combinations comprising antimuscarinic agents and pde4 inhibitors
CA2606549A1 (en) 2005-05-02 2006-11-09 Boehringer Ingelheim International Gmbh Crystalline forms of tiotropium bromide
JP2009504603A (en) * 2005-08-06 2009-02-05 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Method of treating dyspnea by administering a combination of tiotropium salt and salmeterol salt
ES2298049B1 (en) 2006-07-21 2009-10-20 Laboratorios Almirall S.A. PROCEDURE FOR MANUFACTURING BROMIDE OF 3 (R) - (2-HIDROXI-2,2-DITIEN-2-ILACETOXI) -1- (3-PHENOXIPROPIL) -1-AZONIABICICLO (2.2.2) OCTANO.
EP2100599A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
EP2100598A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
US20120220557A1 (en) * 2011-02-17 2012-08-30 Chiesi Farmaceutici S.P.A. Liquid propellant-free formulation comprising an antimuscarinic drug
EP2510928A1 (en) 2011-04-15 2012-10-17 Almirall, S.A. Aclidinium for use in improving the quality of sleep in respiratory patients
WO2013127738A1 (en) * 2012-02-28 2013-09-06 Boehringer Ingelheim International Gmbh Novel propellant-gas-containing tiotropium formulation
WO2015065222A1 (en) * 2013-10-28 2015-05-07 Шолекс Девелопмент Гмбх Pharmaceutical inhaled drug with micronized tiotropium bromide as active ingredient for the treatment of bronchial asthma and chronic obstructive pulmonary disease and method for producing same
TW201835041A (en) 2017-02-17 2018-10-01 印度商托仁特生技有限公司 Compounds with Beta-Adrenergic Agonist and Antimuscarinic Activity
WO2019142214A1 (en) * 2018-01-19 2019-07-25 Cipla Limited Pharmaceutical composition comprising tiotropium for inhalation
CN116173025A (en) * 2018-07-26 2023-05-30 四川海思科制药有限公司 Aerosol pharmaceutical composition containing glycopyrronium salt and indacaterol salt, and preparation method and application thereof
CN111971034A (en) * 2018-07-26 2020-11-20 四川海思科制药有限公司 Aerosol pharmaceutical composition containing glycopyrronium salt and preparation method and application thereof
US11826382B2 (en) 2020-05-01 2023-11-28 Tygrus, LLC Therapeutic material with low pH and low toxicity active against at least one pathogen for addressing patients with respiratory illnesses
US11642372B2 (en) 2020-05-01 2023-05-09 Tygrus, LLC Therapeutic material with low pH and low toxicity active against at least one pathogen for addressing patients with respiratory illnesses
WO2022119661A1 (en) * 2020-12-04 2022-06-09 Tygrus, LLC THERAPEUTIC MATERIAL WITH LOW pH AND LOW TOXICITY ACTIVE AGAINST AT LEAST ONE PATHOGEN FOR ADDRESSING PATIENTS WITH RESPIRATORY ILLNESSES

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19847971A1 (en) * 1998-10-17 1999-09-02 Schiering Filter fire occurrence prevention method

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE283033T1 (en) * 1998-07-24 2004-12-15 Jago Res Ag MEDICAL AEROSOL FORMULATIONS
DE19835346A1 (en) * 1998-08-05 2000-02-10 Boehringer Ingelheim Pharma Two-part capsule for pharmaceutical preparations for powder inhalers
DE19847970A1 (en) * 1998-10-17 2000-04-20 Boehringer Ingelheim Pharma Stable concentrated liquid formulation of inhalable drug, e.g. formoterol or salbutamol, in solution or suspension medium, used after dilution for treatment of respiratory disorders by inhalation
DE19921693A1 (en) * 1999-05-12 2000-11-16 Boehringer Ingelheim Pharma Pharmaceutical composition for treating respiratory disorders, e.g. asthma, comprises combination of anticholinergic and beta-mimetic agents having synergistic bronchospasmolytic activity and reduced side-effects
DE19961300A1 (en) * 1999-12-18 2001-06-21 Asta Medica Ag Storage system for medicinal products in powder form and inhaler equipped with them

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19847971A1 (en) * 1998-10-17 1999-09-02 Schiering Filter fire occurrence prevention method

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CHRONIC OBSTRUCTIVE PULMONARY DISEASE: NEW OPPORTUNITIES FOR DRUG DEVELOPMENT *

Also Published As

Publication number Publication date
ATE362761T1 (en) 2007-06-15
UA74853C2 (en) 2006-02-15
SK7412003A3 (en) 2003-10-07
WO2002038154A1 (en) 2002-05-16
DE50105729D1 (en) 2005-04-28
RS20090105A (en) 2009-07-15
EP1514546B1 (en) 2007-05-23
ES2240549T3 (en) 2005-10-16
DK1335728T3 (en) 2005-04-18
ATE291428T1 (en) 2005-04-15
EP1514546A1 (en) 2005-03-16
HUP0301447A3 (en) 2007-10-29
RS50286B (en) 2009-09-08
JP2005068163A (en) 2005-03-17
AU2791002A (en) 2002-05-21
ES2287629T3 (en) 2007-12-16
DK1514546T3 (en) 2007-09-24
IL155718A (en) 2010-06-30
SI1335728T1 (en) 2005-08-31
CY1106774T1 (en) 2012-05-23
DE10056104A1 (en) 2002-05-23
PT1514546E (en) 2007-06-15
HRP20030378A2 (en) 2005-04-30
BR0115226A (en) 2003-10-07
EA200300503A1 (en) 2004-12-30
KR20030065509A (en) 2003-08-06
ZA200302921B (en) 2004-04-19
AU2007202303B2 (en) 2010-01-21
JP4282594B2 (en) 2009-06-24
DE50112535D1 (en) 2007-07-05
EP1808174A1 (en) 2007-07-18
CZ20031444A3 (en) 2003-08-13
MXPA03004164A (en) 2005-08-16
EA007904B1 (en) 2007-02-27
PL205330B1 (en) 2010-04-30
NO20032111L (en) 2003-07-08
KR100940752B1 (en) 2010-02-11
CA2429012A1 (en) 2002-05-16
ECSP034571A (en) 2003-06-25
EP1335728A1 (en) 2003-08-20
EP1335728B1 (en) 2005-03-23
PL365989A1 (en) 2005-01-24
IL155718A0 (en) 2003-11-23
NO20032111D0 (en) 2003-05-12
NZ526400A (en) 2005-09-30
CN1678318A (en) 2005-10-05
EE200300228A (en) 2003-10-15
SK286950B6 (en) 2009-08-06
YU35503A (en) 2006-05-25
SI1514546T1 (en) 2007-10-31
KR20080079701A (en) 2008-09-01
BG107781A (en) 2004-06-30
SK286939B6 (en) 2009-07-06
AU2007202303A1 (en) 2007-06-14
HUP0301447A2 (en) 2003-10-28
AU2002227910B2 (en) 2007-03-01
JP2004513146A (en) 2004-04-30
JP4282322B2 (en) 2009-06-17
PT1335728E (en) 2005-05-31
KR100886094B1 (en) 2009-02-27

Similar Documents

Publication Publication Date Title
SG167657A1 (en) Novel medicament compositions based on tiotropium salts and on salmeterol salts
YU71901A (en) NOVEL MEDICAMENT COMPOSITIONS, BASED ON ANTICHOLINERGICALLY EFFECTIVE COMPOUNDS AND beta-MIMETICS
MXPA03005340A (en) Novel medicament compositions based on anticholinesterase drugs and on ciclesonides.
YU36302A (en) Novel tiotropium preparation -containing inhalation powder
MXPA03011515A (en) Novel pharmaceutical compositions based on anticholinergic agents, corticosteroids and betamimetic agents.
WO2004037807A3 (en) Medicinal arylethanolamine compounds
IL164373A (en) Benzamide derivatives, pharmaceutical compositions containing them, process for their preparation and use thereof in the manufacture of medicaments and as medicaments in the treatment of diseases associated with cancer
UA85708C2 (en) Benzoxazine-containing pharmaceutical combinations for treating respiratory tract diseases
IL173371A0 (en) Medicaments for inhalation comprising betamimetics and an anticholinergic
CA2436540A1 (en) Pharmaceutical compositions based on anticholinergics and corticosteroids
HRP20040944B1 (en) Medicaments containing betamimetic drugs and a novel anticholinesterase drug
HK1068606A1 (en) Novel aminobenzoephenones
WO2002088100A3 (en) Deuterated 3-piperidinopropiophenone and medicaments containing said compounds
GR20020100478A (en) Anhydrous crystalline valaciclivier hydrochloride
DE69918961D1 (en) IMPROVED INHALATION PRODUCTS
RS89904A (en) Medicaments containing steroids and a novel anticholinesterase drug
MXPA04002401A (en) Novel medicaments for inhalation.
CA2436537A1 (en) Pharmaceutical compositions comprising tiotropium salts and antihistamines
WO2002069944A3 (en) Novel medicament compositions based on anticholinergics and on nk1 receptor antagonists
MY141724A (en) Medicaments containing betamimetic drugs and a novel anticholinesterase drug
ATE284696T1 (en) PHARMACEUTICAL COMPOSITION CONTAINING SALMETEROL AND BUDESONIDE FOR THE TREATMENT OF RESPIRATORY DISEASES
WO2004078761A8 (en) Enantiomerically pure cilazapril,process for preparation
CA2430592A1 (en) New pharmaceutical compositions based on anticholinergics and dopamine agonists
MXPA05003633A (en) 2" oxo-voruscharin and derivatives thereof.