NO173238C - Analogifremgangsmaate for fremstilling av terapeutisk aktive 7-beta-(karboksyalkenoylamino)-3-cefem-4-karboksylsyre-forbindelser - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive 7-beta-(karboksyalkenoylamino)-3-cefem-4-karboksylsyre-forbindelser

Info

Publication number
NO173238C
NO173238C NO843956A NO843956A NO173238C NO 173238 C NO173238 C NO 173238C NO 843956 A NO843956 A NO 843956A NO 843956 A NO843956 A NO 843956A NO 173238 C NO173238 C NO 173238C
Authority
NO
Norway
Prior art keywords
carboxylkenoylamino
cefem
beta
preparation
carboxylic acid
Prior art date
Application number
NO843956A
Other languages
English (en)
Norwegian (no)
Other versions
NO843956L (no
NO173238B (no
Inventor
Yoshio Hamashima
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP58186601A external-priority patent/JPS6078987A/ja
Priority claimed from JP59018563A external-priority patent/JPS60163884A/ja
Priority claimed from JP59100890A external-priority patent/JPH0780892B2/ja
Application filed by Shionogi & Co filed Critical Shionogi & Co
Publication of NO843956L publication Critical patent/NO843956L/no
Priority to NO853806A priority Critical patent/NO176567C/no
Publication of NO173238B publication Critical patent/NO173238B/no
Publication of NO173238C publication Critical patent/NO173238C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/28—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/14—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/08—1,2,4-Thiadiazoles; Hydrogenated 1,2,4-thiadiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65613—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system (X = CH2, O, S, NH) optionally with an additional double bond and/or substituents, e.g. cephalosporins and analogs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Photoreceptors In Electrophotography (AREA)
NO843956A 1983-10-04 1984-10-02 Analogifremgangsmaate for fremstilling av terapeutisk aktive 7-beta-(karboksyalkenoylamino)-3-cefem-4-karboksylsyre-forbindelser NO173238C (no)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NO853806A NO176567C (no) 1983-10-04 1985-09-27 Karboksyalkensyrer

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP58186601A JPS6078987A (ja) 1983-10-04 1983-10-04 アクリルアミドセフアロスポリン類
JP59018563A JPS60163884A (ja) 1984-02-03 1984-02-03 カルボキシアルケンアミドセフアロスポリン
JP59100890A JPH0780892B2 (ja) 1984-05-18 1984-05-18 カルボキシアルケンアミドセフアロスポリン

Publications (3)

Publication Number Publication Date
NO843956L NO843956L (no) 1985-04-09
NO173238B NO173238B (no) 1993-08-09
NO173238C true NO173238C (no) 1993-11-17

Family

ID=27282263

Family Applications (2)

Application Number Title Priority Date Filing Date
NO843956A NO173238C (no) 1983-10-04 1984-10-02 Analogifremgangsmaate for fremstilling av terapeutisk aktive 7-beta-(karboksyalkenoylamino)-3-cefem-4-karboksylsyre-forbindelser
NO853806A NO176567C (no) 1983-10-04 1985-09-27 Karboksyalkensyrer

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO853806A NO176567C (no) 1983-10-04 1985-09-27 Karboksyalkensyrer

Country Status (22)

Country Link
US (3) US4634697A (sv)
EP (1) EP0136721B1 (sv)
KR (2) KR880002376B1 (sv)
AR (1) AR242392A1 (sv)
AT (1) ATE99311T1 (sv)
AU (2) AU575854B2 (sv)
CA (2) CA1238910A (sv)
DE (2) DE136721T1 (sv)
DK (1) DK171043B1 (sv)
ES (3) ES8604602A1 (sv)
FI (1) FI82057C (sv)
GB (3) GB2154580B (sv)
GR (1) GR80544B (sv)
HU (1) HU193298B (sv)
IE (1) IE57744B1 (sv)
IL (3) IL73159A (sv)
MX (1) MX174328B (sv)
NL (1) NL940013I2 (sv)
NO (2) NO173238C (sv)
NZ (2) NZ209634A (sv)
PH (2) PH20223A (sv)
PT (1) PT79287A (sv)

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JPS6153272A (ja) * 1984-08-24 1986-03-17 Shionogi & Co Ltd グルタル酸誘導体の製法
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AT396652B (de) * 1986-07-02 1993-11-25 Shionogi & Co Verfahren zur herstellung von hartgelatinekapsel-zusammensetzungen
US5017380A (en) * 1986-07-02 1991-05-21 Shionogi & Co., Ltd. Gelatin hard capsule containing crystalline hydrate of oral cephalosporin
NZ220764A (en) * 1986-07-02 1989-09-27 Shionogi & Co Crystalline form of 7beta((z)-2-(2-aminothiazol-4-yl)-4- carboxybut-2-enoylamino)-3-cephem-4-carboxylic acid and pharmaceutical compositions
DE3745094B4 (de) * 1986-07-02 2004-12-30 Shionogi & Co., Ltd. Ein kristallines Hydrat der 7ß-[(Z)-2-(2-Aminothiazol-4-yl)-4-carboxybut-2-enoylamino]-3-cephem-4-carbonsäure enthaltende Hartgelatinekapsel-Zusammensetzung
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Also Published As

Publication number Publication date
NL940013I1 (nl) 1994-08-16
NZ218741A (en) 1988-07-28
MX174328B (es) 1994-05-09
ES8604602A1 (es) 1986-02-01
AR242392A1 (es) 1993-03-31
EP0136721A2 (en) 1985-04-10
FI843871A0 (fi) 1984-10-02
KR880002376B1 (ko) 1988-11-03
GB2154580A (en) 1985-09-11
NO843956L (no) 1985-04-09
NZ209634A (en) 1988-07-28
FI843871L (fi) 1985-04-05
PT79287A (en) 1984-11-01
GR80544B (en) 1985-02-05
KR880002684B1 (ko) 1988-12-20
ES8700222A1 (es) 1986-11-16
NO176567B (no) 1995-01-16
PH21766A (en) 1988-02-18
IL73159A (en) 1990-08-31
CA1272713A (en) 1990-08-14
IL84653A0 (en) 1988-04-29
US4634697A (en) 1987-01-06
US4748170A (en) 1988-05-31
PH20223A (en) 1986-10-23
HUT36129A (en) 1985-08-28
DE3486259D1 (de) 1994-02-10
ES8605278A1 (es) 1986-03-16
ES547301A0 (es) 1986-03-16
DK474584D0 (da) 1984-10-03
IE57744B1 (en) 1993-03-24
EP0136721A3 (en) 1986-01-22
ATE99311T1 (de) 1994-01-15
IL73159A0 (en) 1985-01-31
NO853806L (no) 1985-04-09
DE3486259T2 (de) 1994-07-21
GB8726623D0 (en) 1987-12-16
US4912224A (en) 1990-03-27
EP0136721B1 (en) 1993-12-29
DK474584A (da) 1985-04-05
FI82057C (sv) 1991-01-10
NO173238B (no) 1993-08-09
GB8700123D0 (en) 1987-02-11
ES547300A0 (es) 1986-11-16
NO176567C (no) 1995-04-26
FI82057B (fi) 1990-09-28
GB2198727A (en) 1988-06-22
IE842524L (en) 1985-04-04
IL84653A (en) 1990-08-31
HU193298B (en) 1987-09-28
KR850002989A (ko) 1985-05-28
DE136721T1 (de) 1985-08-29
AU1619488A (en) 1988-08-11
NL940013I2 (nl) 1999-06-01
GB8424923D0 (en) 1984-11-07
AU601842B2 (en) 1990-09-20
ES536502A0 (es) 1986-02-01
GB2154580B (en) 1988-08-17
AU3330084A (en) 1985-05-09
CA1238910A (en) 1988-07-05
GB2198727B (en) 1988-11-16
DK171043B1 (da) 1996-04-29
GB2190914A (en) 1987-12-02
CA1272713C (sv) 1990-08-14
GB2190914B (en) 1988-08-17
AU575854B2 (en) 1988-08-11

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