NO162619C - Analogifremgangsmaate for fremstilling av terapeutisk aktive l-aminosyre-derivater - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive l-aminosyre-derivater

Info

Publication number
NO162619C
NO162619C NO840212A NO840212A NO162619C NO 162619 C NO162619 C NO 162619C NO 840212 A NO840212 A NO 840212A NO 840212 A NO840212 A NO 840212A NO 162619 C NO162619 C NO 162619C
Authority
NO
Norway
Prior art keywords
preparation
amino acid
acid derivatives
therapeutic active
analogy procedure
Prior art date
Application number
NO840212A
Other languages
English (en)
Other versions
NO840212L (no
NO162619B (no
Inventor
Gerd Schnorrenberg
Otto Roos
Walter Loesel
Ingrid Wiedemann
Wolfram Gaida
Wolfgang Hoefke
Original Assignee
Boehringer Ingelheim Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg
Publication of NO840212L publication Critical patent/NO840212L/no
Publication of NO162619B publication Critical patent/NO162619B/no
Publication of NO162619C publication Critical patent/NO162619C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO840212A 1983-01-22 1984-01-20 Analogifremgangsmaate for fremstilling av terapeutisk aktive l-aminosyre-derivater NO162619C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19833302125 DE3302125A1 (de) 1983-01-22 1983-01-22 Aminosaeure-derivate, verfahren zu ihrer herstellung und verwendung

Publications (3)

Publication Number Publication Date
NO840212L NO840212L (no) 1984-07-23
NO162619B NO162619B (no) 1989-10-16
NO162619C true NO162619C (no) 1990-01-24

Family

ID=6188976

Family Applications (1)

Application Number Title Priority Date Filing Date
NO840212A NO162619C (no) 1983-01-22 1984-01-20 Analogifremgangsmaate for fremstilling av terapeutisk aktive l-aminosyre-derivater

Country Status (12)

Country Link
US (4) US4555511A (no)
EP (1) EP0116842A3 (no)
JP (1) JPS59139382A (no)
AU (1) AU567124B2 (no)
CA (1) CA1243032A (no)
DE (1) DE3302125A1 (no)
DK (1) DK26784A (no)
ES (1) ES529035A0 (no)
FI (1) FI81106C (no)
IL (1) IL70728A0 (no)
NO (1) NO162619C (no)
ZA (1) ZA84439B (no)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3302125A1 (de) * 1983-01-22 1984-07-26 Boehringer Ingelheim KG, 6507 Ingelheim Aminosaeure-derivate, verfahren zu ihrer herstellung und verwendung
JPS6034993A (ja) * 1983-05-23 1985-02-22 ユーエスヴイー フアーマシユーテイカル コーポレーシヨン 高血圧治療用化合物
CA1244041A (en) * 1984-07-30 1988-11-01 Elijah H. Gold Process for the preparation of cis, endo- octahydrocyclopenta¬b|pyrrole-2-carboxylate
DE3432307A1 (de) * 1984-09-03 1986-04-10 Boehringer Ingelheim KG, 6507 Ingelheim Aminosaeurederivate, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen
CS250699B2 (en) * 1984-12-21 1987-05-14 Pfizer Method of octahydro-6-azaindole's depetidic derivatives production
FR2576901B1 (fr) * 1985-01-31 1987-03-20 Sanofi Sa Nouveaux derives de l'acide a-(oxo-2 hexahydro-2,4,5,6,7,7a thieno (3,2-c) pyridyl-5) phenyl acetique, leur procede de preparation et leur application therapeutique
DE3529960A1 (de) * 1985-08-22 1987-03-05 Boehringer Ingelheim Kg Aminosaeure-derivate, verfahren zu ihrer herstellung und verwendung
FR2620709B1 (fr) * 1987-09-17 1990-09-07 Adir Procede de synthese industrielle du perindopril et de ses principaux intermediaires de synthese
FI94339C (fi) 1989-07-21 1995-08-25 Warner Lambert Co Menetelmä farmaseuttisesti käyttökelpoisen /R-(R*,R*)/-2-(4-fluorifenyyli)- , -dihydroksi-5-(1-metyylietyyli)-3-fenyyli-4-/(fenyyliamino)karbonyyli/-1H-pyrroli-1-heptaanihapon ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi
US5468757A (en) * 1994-01-31 1995-11-21 Eli Lilly And Company 6-azaindole thromboxane synthase inhibitors
CA2318195A1 (en) * 1998-01-16 1999-07-22 Deborah Lynne Bryan Il-8 receptor antagonists
USH1928H (en) * 1998-05-11 2000-12-05 Caterpillar Inc. High viscosity, solvent resistant, thermoset polyetherpolyurethane and A process for making the same
US6908926B1 (en) 1999-04-16 2005-06-21 Novo Nordisk A/S Substituted imidazoles, their preparation and use
FR2807431B1 (fr) 2000-04-06 2002-07-19 Adir Nouveau procede de synthese du perindopril et de ses sels pharmaceutiquement acceptables
US20100298370A1 (en) * 2006-03-20 2010-11-25 Paul Gregor Benzothiazolyl thienopyridine derivatives and uses thereof
WO2016178591A2 (en) 2015-05-05 2016-11-10 Gene Predit, Sa Genetic markers and treatment of male obesity

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB246385A (en) * 1925-07-23 1926-01-28 Albert Edward Hicks Lawn tennis score register
IL58849A (en) * 1978-12-11 1983-03-31 Merck & Co Inc Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them
FR2503155A2 (fr) * 1980-10-02 1982-10-08 Science Union & Cie Nouveaux imino diacides substitues, leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme
FR2487829A2 (fr) * 1979-12-07 1982-02-05 Science Union & Cie Nouveaux imino acides substitues, leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme
DE3177311D1 (de) * 1980-08-30 1994-06-09 Hoechst Ag Aminosäurederivate, Verfahren zu ihrer Herstellung, diese enthaltende Mittel und deren Verwendung.
US4344949A (en) * 1980-10-03 1982-08-17 Warner-Lambert Company Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids
DE3174844D1 (en) * 1980-10-23 1986-07-24 Schering Corp Carboxyalkyl dipeptides, processes for their production and pharmaceutical compositions containing them
ZA817261B (en) * 1980-10-23 1982-09-29 Schering Corp Carboxyalkyl dipeptides,processes for their production and pharmaceutical compositions containing them
JPS57106659A (en) * 1980-11-03 1982-07-02 Ciba Geigy Ag 1-carboxy-azaalkanoylindoline-2-carboxylic acid, manufacture, pharmaceutic medicine containing same and therapeutical use
IN156096B (no) * 1981-03-19 1985-05-11 Usv Pharma Corp
JPS584770A (ja) * 1981-05-18 1983-01-11 メルク・エンド・カムパニ−・インコ−ポレ−テツド 抗高血圧剤としてのイソキノリンカルボン酸誘導体
DE3150486A1 (de) * 1981-12-19 1983-08-25 Merck Patent Gmbh, 6100 Darmstadt Imidazo(4,5-c)pyridine, diese enthaltende pharmazeutische zubereitungen und verfahren zu ihrer herstellung
DE3302125A1 (de) * 1983-01-22 1984-07-26 Boehringer Ingelheim KG, 6507 Ingelheim Aminosaeure-derivate, verfahren zu ihrer herstellung und verwendung

Also Published As

Publication number Publication date
US4766129A (en) 1988-08-23
ZA84439B (en) 1985-09-25
DK26784A (da) 1984-07-23
US4683238A (en) 1987-07-28
US4555511A (en) 1985-11-26
NO840212L (no) 1984-07-23
FI81106B (fi) 1990-05-31
AU567124B2 (en) 1987-11-12
ES8505518A1 (es) 1985-04-16
CA1243032A (en) 1988-10-11
EP0116842A3 (de) 1985-11-27
NO162619B (no) 1989-10-16
FI81106C (fi) 1990-09-10
FI840206A (fi) 1984-07-23
AU2364584A (en) 1984-07-26
IL70728A0 (en) 1984-04-30
EP0116842A2 (de) 1984-08-29
DE3302125A1 (de) 1984-07-26
FI840206A0 (fi) 1984-01-19
DK26784D0 (da) 1984-01-20
US4826855A (en) 1989-05-02
ES529035A0 (es) 1985-04-16
JPS59139382A (ja) 1984-08-10

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