NO854369L - Fremgangsmaate for fremstilling av terapeutisk aktive benzimidazol-derivater - Google Patents

Fremgangsmaate for fremstilling av terapeutisk aktive benzimidazol-derivater

Info

Publication number
NO854369L
NO854369L NO854369A NO854369A NO854369L NO 854369 L NO854369 L NO 854369L NO 854369 A NO854369 A NO 854369A NO 854369 A NO854369 A NO 854369A NO 854369 L NO854369 L NO 854369L
Authority
NO
Norway
Prior art keywords
procedure
preparation
benzimidazole derivatives
therapeutic active
active benzimidazole
Prior art date
Application number
NO854369A
Other languages
English (en)
Other versions
NO164541C (no
NO164541B (no
Inventor
Robert John Ife
Original Assignee
Smith Kline French Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB848427836A external-priority patent/GB8427836D0/en
Priority claimed from GB848432515A external-priority patent/GB8432515D0/en
Priority claimed from GB858518043A external-priority patent/GB8518043D0/en
Application filed by Smith Kline French Lab filed Critical Smith Kline French Lab
Publication of NO854369L publication Critical patent/NO854369L/no
Publication of NO164541B publication Critical patent/NO164541B/no
Publication of NO164541C publication Critical patent/NO164541C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/73Unsubstituted amino or imino radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61Halogen atoms or nitro radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/74Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO854369A 1984-11-02 1985-11-01 Analogifremgangsmaate for fremstilling av terapeutisk aktive benzimidazolderivater. NO164541C (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB848427836A GB8427836D0 (en) 1984-11-02 1984-11-02 Chemical compounds
GB848432515A GB8432515D0 (en) 1984-12-21 1984-12-21 Heterocyclic compounds
GB858518043A GB8518043D0 (en) 1985-07-17 1985-07-17 Heterocyclic compounds

Publications (3)

Publication Number Publication Date
NO854369L true NO854369L (no) 1986-05-05
NO164541B NO164541B (no) 1990-07-09
NO164541C NO164541C (no) 1990-10-17

Family

ID=27262502

Family Applications (1)

Application Number Title Priority Date Filing Date
NO854369A NO164541C (no) 1984-11-02 1985-11-01 Analogifremgangsmaate for fremstilling av terapeutisk aktive benzimidazolderivater.

Country Status (19)

Country Link
EP (1) EP0184322B1 (no)
KR (1) KR930001410B1 (no)
CN (1) CN1013445B (no)
AR (1) AR241592A1 (no)
AU (1) AU576634B2 (no)
CA (1) CA1253150A (no)
DE (1) DE3574873D1 (no)
DK (1) DK501085A (no)
ES (1) ES8701752A1 (no)
FI (1) FI84718C (no)
GR (1) GR852643B (no)
HU (1) HU200763B (no)
IE (1) IE58587B1 (no)
JO (1) JO1406B1 (no)
NO (1) NO164541C (no)
NZ (1) NZ214024A (no)
PH (1) PH22303A (no)
PT (1) PT81420B (no)
ZW (1) ZW19185A1 (no)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3585252D1 (de) * 1984-07-06 1992-03-05 Fisons Plc Benzimidazole, und verfahren zu deren herstellung, deren formulierung und verwendung als magensaeuresekretionshemmende verbindungen.
GB2161160B (en) * 1984-07-06 1989-05-24 Fisons Plc Heterocyclic sulphinyl compounds
GB8610607D0 (en) * 1986-04-30 1986-06-04 Smith Kline French Lab Chemical compounds
GB8621425D0 (en) * 1986-09-05 1986-10-15 Smith Kline French Lab Compounds
DE3722810A1 (de) * 1987-07-10 1989-01-19 Hoechst Ag Substituierte benzimidazole, verfahren zu deren herstellung, diese enthaltende pharmazeutische zubereitungen und deren verwendung
EP0731801B1 (de) * 1993-12-01 2001-10-24 Byk Gulden Lomberg Chemische Fabrik GmbH Substituierte aminoalkylaminopyridine
AU775995B2 (en) 1999-06-07 2004-08-19 Nycomed Gmbh Novel preparation and administration form comprising an acid-labile active compound
EP2336133A1 (en) 2001-10-30 2011-06-22 Conforma Therapeutics Corporation Purine analogs having HSP90-inhibiting activity
WO2004112756A1 (en) 2003-06-26 2004-12-29 Isa Odidi Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient
BRPI0414533A (pt) 2003-09-18 2006-11-07 Conforma Therapeutics Corp composto, composição farmacêutica, e, métodos para inibir um hsp90 e para tratar um indivìduo tendo um distúrbio mediado por hsp90
US8394409B2 (en) 2004-07-01 2013-03-12 Intellipharmaceutics Corp. Controlled extended drug release technology
US10624858B2 (en) 2004-08-23 2020-04-21 Intellipharmaceutics Corp Controlled release composition using transition coating, and method of preparing same
CA2602257A1 (en) * 2005-03-30 2006-10-05 Conforma Therapeutics Corporation Alkynyl pyrrolopyrimidines and related analogs as hsp90-inhibitors
US10064828B1 (en) 2005-12-23 2018-09-04 Intellipharmaceutics Corp. Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems
US9561188B2 (en) 2006-04-03 2017-02-07 Intellipharmaceutics Corporation Controlled release delivery device comprising an organosol coat
US10960077B2 (en) 2006-05-12 2021-03-30 Intellipharmaceutics Corp. Abuse and alcohol resistant drug composition

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL66340A (en) * 1981-08-13 1986-08-31 Haessle Ab Pharmaceutical compositions comprising pyridylmethyl-thiobenzimidazole derivatives,certain such novel derivatives and their preparation
US4575554A (en) * 1983-12-05 1986-03-11 The Upjohn Company Substituted 2-pyridylmethylthio- and sulfinyl-benzimidazoles as gastric antisecretory agents
DE3585252D1 (de) * 1984-07-06 1992-03-05 Fisons Plc Benzimidazole, und verfahren zu deren herstellung, deren formulierung und verwendung als magensaeuresekretionshemmende verbindungen.
EP0178438A1 (en) * 1984-09-19 1986-04-23 Beecham Group Plc Novel compounds
AU568441B2 (en) * 1984-09-24 1987-12-24 Upjohn Company, The 2-(pyridylalkenesulfinyl) benzimidazole derivatives
IL76837A0 (en) * 1984-10-31 1986-02-28 Byk Gulden Lomberg Chem Fab Benzimidazole derivatives,processes for the preparation thereof and pharmaceutical compositions containing them
FI864138A (fi) * 1985-10-16 1987-04-17 Fisons Plc Heterocykliska blandningar.
JPH10513593A (ja) * 1995-11-24 1998-12-22 フィリップス エレクトロニクス ネムローゼ フェンノートシャップ 触覚刺激によって強調された仮想現実を示す方法と、この方法を実行するシステム

Also Published As

Publication number Publication date
IE58587B1 (en) 1993-10-06
FI84718C (fi) 1992-01-10
FI854267L (fi) 1986-05-03
EP0184322B1 (en) 1989-12-20
ZW19185A1 (en) 1986-05-21
FI854267A0 (fi) 1985-10-30
NO164541C (no) 1990-10-17
HU200763B (en) 1990-08-28
HUT39176A (en) 1986-08-28
EP0184322A1 (en) 1986-06-11
KR930001410B1 (ko) 1993-02-27
AU576634B2 (en) 1988-09-01
JO1406B1 (en) 1986-11-30
DK501085A (da) 1986-05-03
AU4920785A (en) 1986-05-08
DE3574873D1 (en) 1990-01-25
NZ214024A (en) 1989-08-29
GR852643B (no) 1986-03-05
ES548409A0 (es) 1986-12-01
IE852684L (en) 1986-05-02
PH22303A (en) 1988-07-22
PT81420A (en) 1985-11-01
NO164541B (no) 1990-07-09
FI84718B (fi) 1991-09-30
KR860004050A (ko) 1986-06-16
DK501085D0 (da) 1985-10-31
PT81420B (pt) 1988-05-27
CN1013445B (zh) 1991-08-07
CN85108133A (zh) 1986-04-10
AR241592A1 (es) 1992-09-30
ES8701752A1 (es) 1986-12-01
CA1253150A (en) 1989-04-25

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