NO171592C - Fremgangsmaate for fremstilling av aktive cinnolin-derivater - Google Patents

Fremgangsmaate for fremstilling av aktive cinnolin-derivater

Info

Publication number
NO171592C
NO171592C NO862141A NO862141A NO171592C NO 171592 C NO171592 C NO 171592C NO 862141 A NO862141 A NO 862141A NO 862141 A NO862141 A NO 862141A NO 171592 C NO171592 C NO 171592C
Authority
NO
Norway
Prior art keywords
cinnolin
derivatives
procedure
active
preparation
Prior art date
Application number
NO862141A
Other languages
English (en)
Other versions
NO171592B (no
NO862141L (no
Inventor
James Franklin Resch
Original Assignee
Ici America Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici America Inc filed Critical Ici America Inc
Publication of NO862141L publication Critical patent/NO862141L/no
Publication of NO171592B publication Critical patent/NO171592B/no
Publication of NO171592C publication Critical patent/NO171592C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/28—Cinnolines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
NO862141A 1985-05-30 1986-05-29 Fremgangsmaate for fremstilling av aktive cinnolin-derivater NO171592C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858513639A GB8513639D0 (en) 1985-05-30 1985-05-30 Cinnoline compounds

Publications (3)

Publication Number Publication Date
NO862141L NO862141L (no) 1986-12-01
NO171592B NO171592B (no) 1992-12-28
NO171592C true NO171592C (no) 1993-04-07

Family

ID=10579908

Family Applications (1)

Application Number Title Priority Date Filing Date
NO862141A NO171592C (no) 1985-05-30 1986-05-29 Fremgangsmaate for fremstilling av aktive cinnolin-derivater

Country Status (25)

Country Link
US (1) US4886800A (no)
EP (1) EP0205272B1 (no)
JP (1) JPH0713062B2 (no)
KR (1) KR900004402B1 (no)
CN (1) CN1014060B (no)
AR (1) AR242026A1 (no)
AT (1) ATE66215T1 (no)
AU (1) AU592086B2 (no)
CA (1) CA1309406C (no)
DE (1) DE3680828D1 (no)
DK (1) DK162221C (no)
ES (3) ES8801803A1 (no)
FI (1) FI85584C (no)
GB (2) GB8513639D0 (no)
GR (1) GR861411B (no)
HU (1) HU199433B (no)
IE (1) IE58782B1 (no)
IL (1) IL78992A0 (no)
MW (1) MW4386A1 (no)
NO (1) NO171592C (no)
PH (1) PH23518A (no)
PL (1) PL149227B1 (no)
PT (1) PT82678B (no)
SU (1) SU1500158A3 (no)
ZA (1) ZA863664B (no)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8702288D0 (en) * 1987-02-02 1987-03-11 Erba Farmitalia Cinnoline-carboxamides
US4925844A (en) * 1988-02-09 1990-05-15 Ici Americas Inc. Antagonizing the pharmacological effects of a benzodiazepine receptor agonist
ATE79540T1 (de) * 1988-02-09 1992-09-15 Ici America Inc Pharmazeutische zusammensetzung.
IL112235A (en) * 1994-01-03 2000-06-29 Acea Pharm Inc 1,4-dihydro-pyrido¬2,3-b¾pyrazine-2,3-dione (5 or 8) oxide derivatives and pharmaceutical compositions containing them
KR20020093849A (ko) 2000-03-21 2002-12-16 파마시아 앤드 업존 캄파니 항바이러스제로서의4-옥소-1,4-디히드로[1,8]나프티리딘-3-카르복스아미드
MXPA02009248A (es) 2000-03-21 2003-03-12 Upjohn Co 4-hidroxicinolin-3-carboxiamidas como agentes antivirales.
EA200201002A1 (ru) 2000-03-21 2003-02-27 Фармация Энд Апджон Компани 4-оксо-1,4-дигидро-3-циннолинкарбоксамиды как противовирусные агенты
AU2001243241A1 (en) 2000-03-21 2001-10-03 Pharmacia And Upjohn Company Llc 4-hydroxy-1,8-naphthyridine-3-carboxamides as antiviral agents
US7465795B2 (en) 2005-12-20 2008-12-16 Astrazeneca Ab Compounds and uses thereof
BRPI0620126A2 (pt) * 2005-12-20 2011-11-01 Astrazeneca Ab composto, composição farmacêutica, uso de um composto, método para modular a atividade de um receptor de gabaa, e, método sintético para fabricar um composto
AR067028A1 (es) * 2007-06-19 2009-09-30 Astrazeneca Ab Compuestos y usos de los mismos 849
WO2010123443A1 (en) * 2009-04-21 2010-10-28 Astrazeneca Ab Pharmaceutical composition comprising 4-amino-8-(2-fluoro-6-methoxy-phenyl)-n- propylcinnoline-3-carboxamide hydrogen sulphate.
WO2010123441A1 (en) * 2009-04-21 2010-10-28 Astrazeneca Ab Crystalline form of 4-amino-8-(2-fluoro-6-methoxy-phenyl)-n-propylcinnoline-3- carboxamide hydrogen sulphate, for treatment of anxiety disorders
WO2010123440A1 (en) * 2009-04-21 2010-10-28 Astrazeneca Ab Pharmaceutical composition comprising 4-amino-8-(2-fluoro-6-methoxy-phenyl)-n- propylcinnoline-3-carboxamide hydrogen sulphate and rate-controlling polymer
US9884828B2 (en) * 2011-05-23 2018-02-06 Imago Pharmaceuticals, Inc. Substituted cinnolines as inhibitors of LRRK2 kinase activity
CN111905828B (zh) * 2020-08-24 2022-04-19 万华化学集团股份有限公司 一种萘基配体mof活性炭复合催化剂及其制备方法和用途

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3657241A (en) * 1970-03-12 1972-04-18 Dow Chemical Co Substituted cinnoline compounds
GB1306839A (en) * 1970-10-16 1973-02-14 Ici Ltd Pharmaceutical compositions
GB1474399A (en) * 1974-08-19 1977-05-25 Ici Ltd Cinnolin-3-yl carboxylic acids and derivatives thereof
US4085103A (en) * 1974-11-07 1978-04-18 Imperial Chemical Industries Limited 6-Substituted-4-hydroxycinnolin-3-yl-carboxylic acids and esters thereof
GB1472766A (en) * 1974-11-07 1977-05-04 Ici Ltd Hydroxycinnoline derivatives processes for their preparation and their use in pharmaceutical compositions
DD123525A1 (no) * 1976-02-10 1977-01-05
US4379929A (en) * 1981-03-19 1983-04-12 Eli Lilly And Company 4(1H)-Oxocinnoline-3-carboxylic acid derivatives
US4729782A (en) * 1983-09-14 1988-03-08 Lafarge Coppee Pollen suppressant comprising a fused pyridazinone
GB8702288D0 (en) * 1987-02-02 1987-03-11 Erba Farmitalia Cinnoline-carboxamides

Also Published As

Publication number Publication date
FI85584B (fi) 1992-01-31
EP0205272B1 (en) 1991-08-14
GR861411B (en) 1986-08-28
ES557522A0 (es) 1988-03-01
AU5781986A (en) 1986-12-04
IL78992A0 (en) 1986-09-30
EP0205272A2 (en) 1986-12-17
ES8802611A1 (es) 1988-10-01
CA1309406C (en) 1992-10-27
DK256386A (da) 1986-12-01
ES555546A0 (es) 1988-02-16
ATE66215T1 (de) 1991-08-15
ZA863664B (en) 1987-03-25
FI862315A (fi) 1986-12-01
KR900004402B1 (ko) 1990-06-25
HUT41012A (en) 1987-03-30
CN1014060B (zh) 1991-09-25
DK162221C (da) 1992-03-02
US4886800A (en) 1989-12-12
SU1500158A3 (ru) 1989-08-07
DK162221B (da) 1991-09-30
ES8801803A1 (es) 1988-02-16
EP0205272A3 (en) 1987-11-19
CN86104358A (zh) 1987-04-01
JPS61280483A (ja) 1986-12-11
IE58782B1 (en) 1993-11-17
KR860008986A (ko) 1986-12-19
PL149227B1 (en) 1990-01-31
NO171592B (no) 1992-12-28
PT82678B (pt) 1988-03-03
AU592086B2 (en) 1990-01-04
ES557790A0 (es) 1988-10-01
PH23518A (en) 1989-08-16
HU199433B (en) 1990-02-28
JPH0713062B2 (ja) 1995-02-15
MW4386A1 (en) 1987-06-19
DE3680828D1 (de) 1991-09-19
FI862315A0 (fi) 1986-05-30
ES8801903A1 (es) 1988-03-01
GB8611419D0 (en) 1986-06-18
AR242026A1 (es) 1993-02-26
IE861267L (en) 1986-11-30
DK256386D0 (da) 1986-05-30
NO862141L (no) 1986-12-01
PT82678A (en) 1986-06-01
GB8513639D0 (en) 1985-07-03
FI85584C (fi) 1992-05-11

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