DK162221C - Cinnolinforbindelser, fremgangsmaade til fremstilling deraf og farmaceutiske midler indeholdende forbindelserne - Google Patents

Cinnolinforbindelser, fremgangsmaade til fremstilling deraf og farmaceutiske midler indeholdende forbindelserne

Info

Publication number
DK162221C
DK162221C DK256386A DK256386A DK162221C DK 162221 C DK162221 C DK 162221C DK 256386 A DK256386 A DK 256386A DK 256386 A DK256386 A DK 256386A DK 162221 C DK162221 C DK 162221C
Authority
DK
Denmark
Prior art keywords
compounds
cinnol
procedures
preparing
pharmaceutical agents
Prior art date
Application number
DK256386A
Other languages
Danish (da)
English (en)
Other versions
DK256386D0 (da
DK256386A (da
DK162221B (da
Inventor
James Franklin Resch
Original Assignee
Ici America Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici America Inc filed Critical Ici America Inc
Publication of DK256386D0 publication Critical patent/DK256386D0/da
Publication of DK256386A publication Critical patent/DK256386A/da
Publication of DK162221B publication Critical patent/DK162221B/da
Application granted granted Critical
Publication of DK162221C publication Critical patent/DK162221C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/28Cinnolines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DK256386A 1985-05-30 1986-05-30 Cinnolinforbindelser, fremgangsmaade til fremstilling deraf og farmaceutiske midler indeholdende forbindelserne DK162221C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8513639 1985-05-30
GB858513639A GB8513639D0 (en) 1985-05-30 1985-05-30 Cinnoline compounds

Publications (4)

Publication Number Publication Date
DK256386D0 DK256386D0 (da) 1986-05-30
DK256386A DK256386A (da) 1986-12-01
DK162221B DK162221B (da) 1991-09-30
DK162221C true DK162221C (da) 1992-03-02

Family

ID=10579908

Family Applications (1)

Application Number Title Priority Date Filing Date
DK256386A DK162221C (da) 1985-05-30 1986-05-30 Cinnolinforbindelser, fremgangsmaade til fremstilling deraf og farmaceutiske midler indeholdende forbindelserne

Country Status (25)

Country Link
US (1) US4886800A (no)
EP (1) EP0205272B1 (no)
JP (1) JPH0713062B2 (no)
KR (1) KR900004402B1 (no)
CN (1) CN1014060B (no)
AR (1) AR242026A1 (no)
AT (1) ATE66215T1 (no)
AU (1) AU592086B2 (no)
CA (1) CA1309406C (no)
DE (1) DE3680828D1 (no)
DK (1) DK162221C (no)
ES (3) ES8801803A1 (no)
FI (1) FI85584C (no)
GB (2) GB8513639D0 (no)
GR (1) GR861411B (no)
HU (1) HU199433B (no)
IE (1) IE58782B1 (no)
IL (1) IL78992A0 (no)
MW (1) MW4386A1 (no)
NO (1) NO171592C (no)
PH (1) PH23518A (no)
PL (1) PL149227B1 (no)
PT (1) PT82678B (no)
SU (1) SU1500158A3 (no)
ZA (1) ZA863664B (no)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8702288D0 (en) * 1987-02-02 1987-03-11 Erba Farmitalia Cinnoline-carboxamides
ATE79540T1 (de) * 1988-02-09 1992-09-15 Ici America Inc Pharmazeutische zusammensetzung.
US4925844A (en) * 1988-02-09 1990-05-15 Ici Americas Inc. Antagonizing the pharmacological effects of a benzodiazepine receptor agonist
EP0743855A1 (en) * 1994-01-03 1996-11-27 Acea Pharmaceuticals, Inc. 8-aza, 6-aza and 6,8-diaza-1,4-dihydroquinoxaline-2,3-diones and the use thereof as antagonists for the glycine/nmda receptor
CN1406228A (zh) 2000-03-21 2003-03-26 法玛西雅厄普约翰美国公司 作为抗病毒剂的4-氧代-1,4-二氢-3-噌啉羧酰胺
BR0108845A (pt) 2000-03-21 2003-05-06 Upjohn Co 4-hidroxi-1,8-naftiridina-3-carboxamidas como agentes antivirais
WO2001074816A1 (en) 2000-03-21 2001-10-11 Pharmacia & Upjohn Company 4-oxo-1,4-dihydro[1,8]naphthyridine-3-carboxamides as antiviral agents
MXPA02009248A (es) 2000-03-21 2003-03-12 Upjohn Co 4-hidroxicinolin-3-carboxiamidas como agentes antivirales.
AU2006327300A1 (en) 2005-12-20 2007-06-28 Astrazeneca Ab Substituted Cinnoline derivatives as GABAa-receptor modulators and method for their synthesis
US7465795B2 (en) 2005-12-20 2008-12-16 Astrazeneca Ab Compounds and uses thereof
TW200911760A (en) * 2007-06-19 2009-03-16 Astrazeneca Ab Compounds and uses thereof
WO2010123440A1 (en) * 2009-04-21 2010-10-28 Astrazeneca Ab Pharmaceutical composition comprising 4-amino-8-(2-fluoro-6-methoxy-phenyl)-n- propylcinnoline-3-carboxamide hydrogen sulphate and rate-controlling polymer
WO2010123443A1 (en) * 2009-04-21 2010-10-28 Astrazeneca Ab Pharmaceutical composition comprising 4-amino-8-(2-fluoro-6-methoxy-phenyl)-n- propylcinnoline-3-carboxamide hydrogen sulphate.
WO2010123441A1 (en) * 2009-04-21 2010-10-28 Astrazeneca Ab Crystalline form of 4-amino-8-(2-fluoro-6-methoxy-phenyl)-n-propylcinnoline-3- carboxamide hydrogen sulphate, for treatment of anxiety disorders
BR112013030095A2 (pt) 2011-05-23 2019-09-24 Elan Pharm Inc inibidores de atividade de lrrk2 cinase
CN111905828B (zh) * 2020-08-24 2022-04-19 万华化学集团股份有限公司 一种萘基配体mof活性炭复合催化剂及其制备方法和用途

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3657241A (en) * 1970-03-12 1972-04-18 Dow Chemical Co Substituted cinnoline compounds
GB1306839A (en) * 1970-10-16 1973-02-14 Ici Ltd Pharmaceutical compositions
GB1474399A (en) * 1974-08-19 1977-05-25 Ici Ltd Cinnolin-3-yl carboxylic acids and derivatives thereof
US4085103A (en) * 1974-11-07 1978-04-18 Imperial Chemical Industries Limited 6-Substituted-4-hydroxycinnolin-3-yl-carboxylic acids and esters thereof
GB1472766A (en) * 1974-11-07 1977-05-04 Ici Ltd Hydroxycinnoline derivatives processes for their preparation and their use in pharmaceutical compositions
DD123525A1 (no) * 1976-02-10 1977-01-05
US4379929A (en) * 1981-03-19 1983-04-12 Eli Lilly And Company 4(1H)-Oxocinnoline-3-carboxylic acid derivatives
US4729782A (en) * 1983-09-14 1988-03-08 Lafarge Coppee Pollen suppressant comprising a fused pyridazinone
GB8702288D0 (en) * 1987-02-02 1987-03-11 Erba Farmitalia Cinnoline-carboxamides

Also Published As

Publication number Publication date
NO862141L (no) 1986-12-01
ES8801903A1 (es) 1988-03-01
HUT41012A (en) 1987-03-30
PT82678A (en) 1986-06-01
DE3680828D1 (de) 1991-09-19
FI862315A0 (fi) 1986-05-30
HU199433B (en) 1990-02-28
AU5781986A (en) 1986-12-04
US4886800A (en) 1989-12-12
PL149227B1 (en) 1990-01-31
IE58782B1 (en) 1993-11-17
IE861267L (en) 1986-11-30
CN1014060B (zh) 1991-09-25
GB8611419D0 (en) 1986-06-18
NO171592B (no) 1992-12-28
DK256386D0 (da) 1986-05-30
ES8801803A1 (es) 1988-02-16
FI85584C (fi) 1992-05-11
GB8513639D0 (en) 1985-07-03
GR861411B (en) 1986-08-28
JPS61280483A (ja) 1986-12-11
ZA863664B (en) 1987-03-25
FI85584B (fi) 1992-01-31
ES555546A0 (es) 1988-02-16
ES8802611A1 (es) 1988-10-01
DK256386A (da) 1986-12-01
EP0205272B1 (en) 1991-08-14
KR860008986A (ko) 1986-12-19
SU1500158A3 (ru) 1989-08-07
JPH0713062B2 (ja) 1995-02-15
NO171592C (no) 1993-04-07
IL78992A0 (en) 1986-09-30
PH23518A (en) 1989-08-16
ES557522A0 (es) 1988-03-01
AR242026A1 (es) 1993-02-26
KR900004402B1 (ko) 1990-06-25
MW4386A1 (en) 1987-06-19
CN86104358A (zh) 1987-04-01
DK162221B (da) 1991-09-30
AU592086B2 (en) 1990-01-04
EP0205272A3 (en) 1987-11-19
CA1309406C (en) 1992-10-27
FI862315A (fi) 1986-12-01
PT82678B (pt) 1988-03-03
EP0205272A2 (en) 1986-12-17
ATE66215T1 (de) 1991-08-15
ES557790A0 (es) 1988-10-01

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Legal Events

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PUP Patent expired