DK256386A - Cinnolinderivater - Google Patents

Cinnolinderivater Download PDF

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Publication number
DK256386A
DK256386A DK256386A DK256386A DK256386A DK 256386 A DK256386 A DK 256386A DK 256386 A DK256386 A DK 256386A DK 256386 A DK256386 A DK 256386A DK 256386 A DK256386 A DK 256386A
Authority
DK
Denmark
Prior art keywords
cinnoline derivatives
cinnoline
derivatives
Prior art date
Application number
DK256386A
Other languages
English (en)
Other versions
DK162221C (da
DK256386D0 (da
DK162221B (da
Inventor
James Franklin Resch
Original Assignee
Ici America Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici America Inc filed Critical Ici America Inc
Publication of DK256386D0 publication Critical patent/DK256386D0/da
Publication of DK256386A publication Critical patent/DK256386A/da
Publication of DK162221B publication Critical patent/DK162221B/da
Application granted granted Critical
Publication of DK162221C publication Critical patent/DK162221C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/28Cinnolines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DK256386A 1985-05-30 1986-05-30 Cinnolinforbindelser, fremgangsmaade til fremstilling deraf og farmaceutiske midler indeholdende forbindelserne DK162221C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB858513639A GB8513639D0 (en) 1985-05-30 1985-05-30 Cinnoline compounds
GB8513639 1985-05-30

Publications (4)

Publication Number Publication Date
DK256386D0 DK256386D0 (da) 1986-05-30
DK256386A true DK256386A (da) 1986-12-01
DK162221B DK162221B (da) 1991-09-30
DK162221C DK162221C (da) 1992-03-02

Family

ID=10579908

Family Applications (1)

Application Number Title Priority Date Filing Date
DK256386A DK162221C (da) 1985-05-30 1986-05-30 Cinnolinforbindelser, fremgangsmaade til fremstilling deraf og farmaceutiske midler indeholdende forbindelserne

Country Status (25)

Country Link
US (1) US4886800A (da)
EP (1) EP0205272B1 (da)
JP (1) JPH0713062B2 (da)
KR (1) KR900004402B1 (da)
CN (1) CN1014060B (da)
AR (1) AR242026A1 (da)
AT (1) ATE66215T1 (da)
AU (1) AU592086B2 (da)
CA (1) CA1309406C (da)
DE (1) DE3680828D1 (da)
DK (1) DK162221C (da)
ES (3) ES8801803A1 (da)
FI (1) FI85584C (da)
GB (2) GB8513639D0 (da)
GR (1) GR861411B (da)
HU (1) HU199433B (da)
IE (1) IE58782B1 (da)
IL (1) IL78992A0 (da)
MW (1) MW4386A1 (da)
NO (1) NO171592C (da)
PH (1) PH23518A (da)
PL (1) PL149227B1 (da)
PT (1) PT82678B (da)
SU (1) SU1500158A3 (da)
ZA (1) ZA863664B (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8702288D0 (en) * 1987-02-02 1987-03-11 Erba Farmitalia Cinnoline-carboxamides
EP0328282B1 (en) * 1988-02-09 1992-08-19 Ici Americas Inc. Pharmaceutical
US4925844A (en) * 1988-02-09 1990-05-15 Ici Americas Inc. Antagonizing the pharmacological effects of a benzodiazepine receptor agonist
IL112235A (en) * 1994-01-03 2000-06-29 Acea Pharm Inc 1,4-dihydro-pyrido¬2,3-b¾pyrazine-2,3-dione (5 or 8) oxide derivatives and pharmaceutical compositions containing them
DE60100999T2 (de) 2000-03-21 2004-09-02 Pharmacia & Upjohn Co., Kalamazoo 4-oxo-1,4-dihydro-3-cinnolinecarbonsäure-amide als antivirusmittel
WO2001070742A1 (en) 2000-03-21 2001-09-27 Pharmacia & Upjohn Company 4-hydroxy-1,8-naphthyridine-3-carboxamides as antiviral agents
JP2003529601A (ja) 2000-03-21 2003-10-07 ファルマシア・アンド・アップジョン・カンパニー 抗ウイルス剤としての4−オキソ−1,4−ジヒドロ[1,8]ナフチリジン−3−カルボキサミド
BR0109391A (pt) 2000-03-21 2003-06-03 Upjohn Co 4-hidroxicinolina-3-carboxiamidas como agentes antivirais
US7465795B2 (en) 2005-12-20 2008-12-16 Astrazeneca Ab Compounds and uses thereof
CA2634305A1 (en) * 2005-12-20 2007-06-28 Marc Chapdelaine Substituted cinnoline derivatives as gabaa-receptor modulators and method for their synthesis
AR067028A1 (es) * 2007-06-19 2009-09-30 Astrazeneca Ab Compuestos y usos de los mismos 849
WO2010123443A1 (en) * 2009-04-21 2010-10-28 Astrazeneca Ab Pharmaceutical composition comprising 4-amino-8-(2-fluoro-6-methoxy-phenyl)-n- propylcinnoline-3-carboxamide hydrogen sulphate.
WO2010123441A1 (en) * 2009-04-21 2010-10-28 Astrazeneca Ab Crystalline form of 4-amino-8-(2-fluoro-6-methoxy-phenyl)-n-propylcinnoline-3- carboxamide hydrogen sulphate, for treatment of anxiety disorders
WO2010123440A1 (en) * 2009-04-21 2010-10-28 Astrazeneca Ab Pharmaceutical composition comprising 4-amino-8-(2-fluoro-6-methoxy-phenyl)-n- propylcinnoline-3-carboxamide hydrogen sulphate and rate-controlling polymer
RU2017140639A (ru) * 2011-05-23 2019-02-12 Элан Фармасьютикалз, Инк. Ингибиторы активности киназы lrrk2
CN111905828B (zh) * 2020-08-24 2022-04-19 万华化学集团股份有限公司 一种萘基配体mof活性炭复合催化剂及其制备方法和用途

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3657241A (en) * 1970-03-12 1972-04-18 Dow Chemical Co Substituted cinnoline compounds
GB1306839A (en) * 1970-10-16 1973-02-14 Ici Ltd Pharmaceutical compositions
GB1474399A (en) * 1974-08-19 1977-05-25 Ici Ltd Cinnolin-3-yl carboxylic acids and derivatives thereof
US4085103A (en) * 1974-11-07 1978-04-18 Imperial Chemical Industries Limited 6-Substituted-4-hydroxycinnolin-3-yl-carboxylic acids and esters thereof
GB1472766A (en) * 1974-11-07 1977-05-04 Ici Ltd Hydroxycinnoline derivatives processes for their preparation and their use in pharmaceutical compositions
DD123525A1 (da) * 1976-02-10 1977-01-05
US4379929A (en) * 1981-03-19 1983-04-12 Eli Lilly And Company 4(1H)-Oxocinnoline-3-carboxylic acid derivatives
US4729782A (en) * 1983-09-14 1988-03-08 Lafarge Coppee Pollen suppressant comprising a fused pyridazinone
GB8702288D0 (en) * 1987-02-02 1987-03-11 Erba Farmitalia Cinnoline-carboxamides

Also Published As

Publication number Publication date
KR900004402B1 (ko) 1990-06-25
CA1309406C (en) 1992-10-27
ES557522A0 (es) 1988-03-01
DK162221C (da) 1992-03-02
IE861267L (en) 1986-11-30
IL78992A0 (en) 1986-09-30
EP0205272B1 (en) 1991-08-14
HU199433B (en) 1990-02-28
NO171592B (no) 1992-12-28
ATE66215T1 (de) 1991-08-15
DK256386D0 (da) 1986-05-30
PL149227B1 (en) 1990-01-31
DK162221B (da) 1991-09-30
EP0205272A2 (en) 1986-12-17
GR861411B (en) 1986-08-28
AU592086B2 (en) 1990-01-04
ES8802611A1 (es) 1988-10-01
HUT41012A (en) 1987-03-30
FI85584B (fi) 1992-01-31
ZA863664B (en) 1987-03-25
PH23518A (en) 1989-08-16
MW4386A1 (en) 1987-06-19
ES555546A0 (es) 1988-02-16
IE58782B1 (en) 1993-11-17
AR242026A1 (es) 1993-02-26
ES8801903A1 (es) 1988-03-01
US4886800A (en) 1989-12-12
GB8611419D0 (en) 1986-06-18
JPH0713062B2 (ja) 1995-02-15
SU1500158A3 (ru) 1989-08-07
NO862141L (no) 1986-12-01
DE3680828D1 (de) 1991-09-19
FI862315A0 (fi) 1986-05-30
FI862315A (fi) 1986-12-01
PT82678B (pt) 1988-03-03
CN1014060B (zh) 1991-09-25
ES8801803A1 (es) 1988-02-16
FI85584C (fi) 1992-05-11
EP0205272A3 (en) 1987-11-19
JPS61280483A (ja) 1986-12-11
KR860008986A (ko) 1986-12-19
PT82678A (en) 1986-06-01
ES557790A0 (es) 1988-10-01
GB8513639D0 (en) 1985-07-03
AU5781986A (en) 1986-12-04
NO171592C (no) 1993-04-07
CN86104358A (zh) 1987-04-01

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PUP Patent expired