DK256386A - Cinnolinderivater - Google Patents
Cinnolinderivater Download PDFInfo
- Publication number
- DK256386A DK256386A DK256386A DK256386A DK256386A DK 256386 A DK256386 A DK 256386A DK 256386 A DK256386 A DK 256386A DK 256386 A DK256386 A DK 256386A DK 256386 A DK256386 A DK 256386A
- Authority
- DK
- Denmark
- Prior art keywords
- cinnoline derivatives
- cinnoline
- derivatives
- Prior art date
Links
- 125000000259 cinnolinyl group Chemical class N1=NC(=CC2=CC=CC=C12)* 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
- C07D237/28—Cinnolines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB858513639A GB8513639D0 (en) | 1985-05-30 | 1985-05-30 | Cinnoline compounds |
GB8513639 | 1985-05-30 |
Publications (4)
Publication Number | Publication Date |
---|---|
DK256386D0 DK256386D0 (da) | 1986-05-30 |
DK256386A true DK256386A (da) | 1986-12-01 |
DK162221B DK162221B (da) | 1991-09-30 |
DK162221C DK162221C (da) | 1992-03-02 |
Family
ID=10579908
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK256386A DK162221C (da) | 1985-05-30 | 1986-05-30 | Cinnolinforbindelser, fremgangsmaade til fremstilling deraf og farmaceutiske midler indeholdende forbindelserne |
Country Status (25)
Country | Link |
---|---|
US (1) | US4886800A (da) |
EP (1) | EP0205272B1 (da) |
JP (1) | JPH0713062B2 (da) |
KR (1) | KR900004402B1 (da) |
CN (1) | CN1014060B (da) |
AR (1) | AR242026A1 (da) |
AT (1) | ATE66215T1 (da) |
AU (1) | AU592086B2 (da) |
CA (1) | CA1309406C (da) |
DE (1) | DE3680828D1 (da) |
DK (1) | DK162221C (da) |
ES (3) | ES8801803A1 (da) |
FI (1) | FI85584C (da) |
GB (2) | GB8513639D0 (da) |
GR (1) | GR861411B (da) |
HU (1) | HU199433B (da) |
IE (1) | IE58782B1 (da) |
IL (1) | IL78992A0 (da) |
MW (1) | MW4386A1 (da) |
NO (1) | NO171592C (da) |
PH (1) | PH23518A (da) |
PL (1) | PL149227B1 (da) |
PT (1) | PT82678B (da) |
SU (1) | SU1500158A3 (da) |
ZA (1) | ZA863664B (da) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8702288D0 (en) * | 1987-02-02 | 1987-03-11 | Erba Farmitalia | Cinnoline-carboxamides |
EP0328282B1 (en) * | 1988-02-09 | 1992-08-19 | Ici Americas Inc. | Pharmaceutical |
US4925844A (en) * | 1988-02-09 | 1990-05-15 | Ici Americas Inc. | Antagonizing the pharmacological effects of a benzodiazepine receptor agonist |
IL112235A (en) * | 1994-01-03 | 2000-06-29 | Acea Pharm Inc | 1,4-dihydro-pyrido¬2,3-b¾pyrazine-2,3-dione (5 or 8) oxide derivatives and pharmaceutical compositions containing them |
DE60100999T2 (de) | 2000-03-21 | 2004-09-02 | Pharmacia & Upjohn Co., Kalamazoo | 4-oxo-1,4-dihydro-3-cinnolinecarbonsäure-amide als antivirusmittel |
WO2001070742A1 (en) | 2000-03-21 | 2001-09-27 | Pharmacia & Upjohn Company | 4-hydroxy-1,8-naphthyridine-3-carboxamides as antiviral agents |
JP2003529601A (ja) | 2000-03-21 | 2003-10-07 | ファルマシア・アンド・アップジョン・カンパニー | 抗ウイルス剤としての4−オキソ−1,4−ジヒドロ[1,8]ナフチリジン−3−カルボキサミド |
BR0109391A (pt) | 2000-03-21 | 2003-06-03 | Upjohn Co | 4-hidroxicinolina-3-carboxiamidas como agentes antivirais |
US7465795B2 (en) | 2005-12-20 | 2008-12-16 | Astrazeneca Ab | Compounds and uses thereof |
CA2634305A1 (en) * | 2005-12-20 | 2007-06-28 | Marc Chapdelaine | Substituted cinnoline derivatives as gabaa-receptor modulators and method for their synthesis |
AR067028A1 (es) * | 2007-06-19 | 2009-09-30 | Astrazeneca Ab | Compuestos y usos de los mismos 849 |
WO2010123443A1 (en) * | 2009-04-21 | 2010-10-28 | Astrazeneca Ab | Pharmaceutical composition comprising 4-amino-8-(2-fluoro-6-methoxy-phenyl)-n- propylcinnoline-3-carboxamide hydrogen sulphate. |
WO2010123441A1 (en) * | 2009-04-21 | 2010-10-28 | Astrazeneca Ab | Crystalline form of 4-amino-8-(2-fluoro-6-methoxy-phenyl)-n-propylcinnoline-3- carboxamide hydrogen sulphate, for treatment of anxiety disorders |
WO2010123440A1 (en) * | 2009-04-21 | 2010-10-28 | Astrazeneca Ab | Pharmaceutical composition comprising 4-amino-8-(2-fluoro-6-methoxy-phenyl)-n- propylcinnoline-3-carboxamide hydrogen sulphate and rate-controlling polymer |
RU2017140639A (ru) * | 2011-05-23 | 2019-02-12 | Элан Фармасьютикалз, Инк. | Ингибиторы активности киназы lrrk2 |
CN111905828B (zh) * | 2020-08-24 | 2022-04-19 | 万华化学集团股份有限公司 | 一种萘基配体mof活性炭复合催化剂及其制备方法和用途 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3657241A (en) * | 1970-03-12 | 1972-04-18 | Dow Chemical Co | Substituted cinnoline compounds |
GB1306839A (en) * | 1970-10-16 | 1973-02-14 | Ici Ltd | Pharmaceutical compositions |
GB1474399A (en) * | 1974-08-19 | 1977-05-25 | Ici Ltd | Cinnolin-3-yl carboxylic acids and derivatives thereof |
US4085103A (en) * | 1974-11-07 | 1978-04-18 | Imperial Chemical Industries Limited | 6-Substituted-4-hydroxycinnolin-3-yl-carboxylic acids and esters thereof |
GB1472766A (en) * | 1974-11-07 | 1977-05-04 | Ici Ltd | Hydroxycinnoline derivatives processes for their preparation and their use in pharmaceutical compositions |
DD123525A1 (da) * | 1976-02-10 | 1977-01-05 | ||
US4379929A (en) * | 1981-03-19 | 1983-04-12 | Eli Lilly And Company | 4(1H)-Oxocinnoline-3-carboxylic acid derivatives |
US4729782A (en) * | 1983-09-14 | 1988-03-08 | Lafarge Coppee | Pollen suppressant comprising a fused pyridazinone |
GB8702288D0 (en) * | 1987-02-02 | 1987-03-11 | Erba Farmitalia | Cinnoline-carboxamides |
-
1985
- 1985-05-30 GB GB858513639A patent/GB8513639D0/en active Pending
-
1986
- 1986-05-09 GB GB868611419A patent/GB8611419D0/en active Pending
- 1986-05-13 IE IE126786A patent/IE58782B1/en not_active IP Right Cessation
- 1986-05-16 ZA ZA863664A patent/ZA863664B/xx unknown
- 1986-05-20 PH PH33792A patent/PH23518A/en unknown
- 1986-05-22 AU AU57819/86A patent/AU592086B2/en not_active Ceased
- 1986-05-23 EP EP86303963A patent/EP0205272B1/en not_active Expired - Lifetime
- 1986-05-23 DE DE8686303963T patent/DE3680828D1/de not_active Expired - Lifetime
- 1986-05-23 AT AT86303963T patent/ATE66215T1/de not_active IP Right Cessation
- 1986-05-28 HU HU862243A patent/HU199433B/hu not_active IP Right Cessation
- 1986-05-29 CA CA000510335A patent/CA1309406C/en not_active Expired - Lifetime
- 1986-05-29 US US06/868,791 patent/US4886800A/en not_active Expired - Lifetime
- 1986-05-29 NO NO862141A patent/NO171592C/no unknown
- 1986-05-29 SU SU864027693A patent/SU1500158A3/ru active
- 1986-05-30 GR GR861411A patent/GR861411B/el unknown
- 1986-05-30 ES ES555546A patent/ES8801803A1/es not_active Expired
- 1986-05-30 FI FI862315A patent/FI85584C/fi not_active IP Right Cessation
- 1986-05-30 KR KR1019860004274A patent/KR900004402B1/ko not_active IP Right Cessation
- 1986-05-30 PL PL1986259791A patent/PL149227B1/pl unknown
- 1986-05-30 JP JP61123840A patent/JPH0713062B2/ja not_active Expired - Lifetime
- 1986-05-30 CN CN86104358A patent/CN1014060B/zh not_active Expired
- 1986-05-30 PT PT82678A patent/PT82678B/pt unknown
- 1986-05-30 DK DK256386A patent/DK162221C/da not_active IP Right Cessation
- 1986-05-30 AR AR86304166A patent/AR242026A1/es active
- 1986-05-30 MW MW43/86A patent/MW4386A1/xx unknown
- 1986-06-02 IL IL78992A patent/IL78992A0/xx not_active IP Right Cessation
-
1987
- 1987-04-30 ES ES557522A patent/ES8801903A1/es not_active Expired
- 1987-12-16 ES ES557790A patent/ES8802611A1/es not_active Expired
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUP | Patent expired |