ES555546A0 - Procedimiento para preparar derivados de cinalina. - Google Patents

Procedimiento para preparar derivados de cinalina.

Info

Publication number
ES555546A0
ES555546A0 ES555546A ES555546A ES555546A0 ES 555546 A0 ES555546 A0 ES 555546A0 ES 555546 A ES555546 A ES 555546A ES 555546 A ES555546 A ES 555546A ES 555546 A0 ES555546 A0 ES 555546A0
Authority
ES
Spain
Prior art keywords
cinaline
derivatives
preparing
procedure
preparing cinaline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES555546A
Other languages
English (en)
Other versions
ES8801803A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zeneca Inc
Original Assignee
ICI Americas Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ICI Americas Inc filed Critical ICI Americas Inc
Publication of ES8801803A1 publication Critical patent/ES8801803A1/es
Publication of ES555546A0 publication Critical patent/ES555546A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/28—Cinnolines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
ES555546A 1985-05-30 1986-05-30 Procedimiento para preparar derivados de cinalina. Expired ES8801803A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858513639A GB8513639D0 (en) 1985-05-30 1985-05-30 Cinnoline compounds

Publications (2)

Publication Number Publication Date
ES8801803A1 ES8801803A1 (es) 1988-02-16
ES555546A0 true ES555546A0 (es) 1988-02-16

Family

ID=10579908

Family Applications (3)

Application Number Title Priority Date Filing Date
ES555546A Expired ES8801803A1 (es) 1985-05-30 1986-05-30 Procedimiento para preparar derivados de cinalina.
ES557522A Expired ES8801903A1 (es) 1985-05-30 1987-04-30 Procedimiento para preparar derivados de cinolina
ES557790A Expired ES8802611A1 (es) 1985-05-30 1987-12-16 Procedimiento para preparar 4-amino-8-butilinolina-3-n-ciclopropilmetil carboxamida.

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES557522A Expired ES8801903A1 (es) 1985-05-30 1987-04-30 Procedimiento para preparar derivados de cinolina
ES557790A Expired ES8802611A1 (es) 1985-05-30 1987-12-16 Procedimiento para preparar 4-amino-8-butilinolina-3-n-ciclopropilmetil carboxamida.

Country Status (25)

Country Link
US (1) US4886800A (es)
EP (1) EP0205272B1 (es)
JP (1) JPH0713062B2 (es)
KR (1) KR900004402B1 (es)
CN (1) CN1014060B (es)
AR (1) AR242026A1 (es)
AT (1) ATE66215T1 (es)
AU (1) AU592086B2 (es)
CA (1) CA1309406C (es)
DE (1) DE3680828D1 (es)
DK (1) DK162221C (es)
ES (3) ES8801803A1 (es)
FI (1) FI85584C (es)
GB (2) GB8513639D0 (es)
GR (1) GR861411B (es)
HU (1) HU199433B (es)
IE (1) IE58782B1 (es)
IL (1) IL78992A0 (es)
MW (1) MW4386A1 (es)
NO (1) NO171592C (es)
PH (1) PH23518A (es)
PL (1) PL149227B1 (es)
PT (1) PT82678B (es)
SU (1) SU1500158A3 (es)
ZA (1) ZA863664B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8702288D0 (en) * 1987-02-02 1987-03-11 Erba Farmitalia Cinnoline-carboxamides
US4925844A (en) * 1988-02-09 1990-05-15 Ici Americas Inc. Antagonizing the pharmacological effects of a benzodiazepine receptor agonist
EP0328282B1 (en) * 1988-02-09 1992-08-19 Ici Americas Inc. Pharmaceutical
US5620978A (en) * 1994-01-03 1997-04-15 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon, Eugene Oregon 8-aza, 6-aza and 6,8-diaza-1,4-dihydroquinoxaline-2,3-diones and the use thereof as antagonists for the glycine/NMDA receptor
KR20020093849A (ko) 2000-03-21 2002-12-16 파마시아 앤드 업존 캄파니 항바이러스제로서의4-옥소-1,4-디히드로[1,8]나프티리딘-3-카르복스아미드
JP2003531195A (ja) 2000-03-21 2003-10-21 ファルマシア・アンド・アップジョン・カンパニー 抗ウイルス剤としての４−ヒドロキシシンノリン−３−カルボキサミド
US6624160B2 (en) 2000-03-21 2003-09-23 Pharmacia & Upjohn Co. 4-oxo-1,4-dihydro-3-cinnolinecarboxamides as antiviral agents
US6413958B2 (en) 2000-03-21 2002-07-02 Pharmacia & Upjohn Company 4-hydroxy-1,8-naphthyridine-3-carboxamides as antiviral agents
US7465795B2 (en) 2005-12-20 2008-12-16 Astrazeneca Ab Compounds and uses thereof
KR20080080206A (ko) * 2005-12-20 2008-09-02 아스트라제네카 아베 Ｇａｂａａ-수용체 조절제로서의 치환된 신놀린 유도체 및그의 합성 방법
TW200911760A (en) * 2007-06-19 2009-03-16 Astrazeneca Ab Compounds and uses thereof
WO2010123443A1 (en) * 2009-04-21 2010-10-28 Astrazeneca Ab Pharmaceutical composition comprising 4-amino-8-(2-fluoro-6-methoxy-phenyl)-n- propylcinnoline-3-carboxamide hydrogen sulphate.
WO2010123440A1 (en) * 2009-04-21 2010-10-28 Astrazeneca Ab Pharmaceutical composition comprising 4-amino-8-(2-fluoro-6-methoxy-phenyl)-n- propylcinnoline-3-carboxamide hydrogen sulphate and rate-controlling polymer
WO2010123441A1 (en) * 2009-04-21 2010-10-28 Astrazeneca Ab Crystalline form of 4-amino-8-(2-fluoro-6-methoxy-phenyl)-n-propylcinnoline-3- carboxamide hydrogen sulphate, for treatment of anxiety disorders
EP2726465A1 (en) * 2011-05-23 2014-05-07 Elan Pharmaceuticals Inc. Inhibitors of lrrk2 kinase activity
CN111905828B (zh) * 2020-08-24 2022-04-19 万华化学集团股份有限公司 一种萘基配体mof活性炭复合催化剂及其制备方法和用途

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3657241A (en) * 1970-03-12 1972-04-18 Dow Chemical Co Substituted cinnoline compounds
GB1306839A (en) * 1970-10-16 1973-02-14 Ici Ltd Pharmaceutical compositions
GB1474399A (en) * 1974-08-19 1977-05-25 Ici Ltd Cinnolin-3-yl carboxylic acids and derivatives thereof
US4085103A (en) * 1974-11-07 1978-04-18 Imperial Chemical Industries Limited 6-Substituted-4-hydroxycinnolin-3-yl-carboxylic acids and esters thereof
GB1472766A (en) * 1974-11-07 1977-05-04 Ici Ltd Hydroxycinnoline derivatives processes for their preparation and their use in pharmaceutical compositions
DD123525A1 (es) * 1976-02-10 1977-01-05
US4379929A (en) * 1981-03-19 1983-04-12 Eli Lilly And Company 4(1H)-Oxocinnoline-3-carboxylic acid derivatives
US4729782A (en) * 1983-09-14 1988-03-08 Lafarge Coppee Pollen suppressant comprising a fused pyridazinone
GB8702288D0 (en) * 1987-02-02 1987-03-11 Erba Farmitalia Cinnoline-carboxamides

Also Published As

Publication number Publication date
ES8802611A1 (es) 1988-10-01
AU592086B2 (en) 1990-01-04
CN86104358A (zh) 1987-04-01
EP0205272A3 (en) 1987-11-19
ATE66215T1 (de) 1991-08-15
CN1014060B (zh) 1991-09-25
ZA863664B (en) 1987-03-25
NO171592C (no) 1993-04-07
US4886800A (en) 1989-12-12
IL78992A0 (en) 1986-09-30
DK256386D0 (da) 1986-05-30
IE861267L (en) 1986-11-30
MW4386A1 (en) 1987-06-19
FI85584C (fi) 1992-05-11
NO862141L (no) 1986-12-01
PT82678B (pt) 1988-03-03
FI862315A (fi) 1986-12-01
JPH0713062B2 (ja) 1995-02-15
PL149227B1 (en) 1990-01-31
EP0205272A2 (en) 1986-12-17
KR900004402B1 (ko) 1990-06-25
DE3680828D1 (de) 1991-09-19
FI862315A0 (fi) 1986-05-30
NO171592B (no) 1992-12-28
GB8611419D0 (en) 1986-06-18
ES8801903A1 (es) 1988-03-01
GR861411B (en) 1986-08-28
AR242026A1 (es) 1993-02-26
DK256386A (da) 1986-12-01
EP0205272B1 (en) 1991-08-14
GB8513639D0 (en) 1985-07-03
PH23518A (en) 1989-08-16
JPS61280483A (ja) 1986-12-11
DK162221B (da) 1991-09-30
HUT41012A (en) 1987-03-30
ES8801803A1 (es) 1988-02-16
HU199433B (en) 1990-02-28
CA1309406C (en) 1992-10-27
AU5781986A (en) 1986-12-04
FI85584B (fi) 1992-01-31
ES557522A0 (es) 1988-03-01
IE58782B1 (en) 1993-11-17
PT82678A (en) 1986-06-01
KR860008986A (ko) 1986-12-19
ES557790A0 (es) 1988-10-01
DK162221C (da) 1992-03-02
SU1500158A3 (ru) 1989-08-07

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20071112