NO155347C - Analogifremgangsmaate ved fremstilling av et terapeutisk aktivt (6r,7r)-7-((z)-2-(2-amino-tiazol-4-yl)-2-(2-karboksy-prop-2-oksyimino)-acetamido)-3-(1-pyridiniummetyl)cef-3-em-4-karboksylat. - Google Patents
Analogifremgangsmaate ved fremstilling av et terapeutisk aktivt (6r,7r)-7-((z)-2-(2-amino-tiazol-4-yl)-2-(2-karboksy-prop-2-oksyimino)-acetamido)-3-(1-pyridiniummetyl)cef-3-em-4-karboksylat.Info
- Publication number
- NO155347C NO155347C NO791731A NO791731A NO155347C NO 155347 C NO155347 C NO 155347C NO 791731 A NO791731 A NO 791731A NO 791731 A NO791731 A NO 791731A NO 155347 C NO155347 C NO 155347C
- Authority
- NO
- Norway
- Prior art keywords
- tiazol
- pyridiniummethyl
- oxyimino
- cef
- acetamido
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB2291178 | 1978-05-26 | ||
GB2291378 | 1978-05-26 |
Publications (3)
Publication Number | Publication Date |
---|---|
NO155347B NO155347B (no) | 1966-12-08 |
NO791731L NO791731L (no) | 1979-11-27 |
NO155347C true NO155347C (no) | 1987-03-18 |
Family
ID=26256190
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO791731A NO155347C (no) | 1978-05-26 | 1979-05-25 | Analogifremgangsmaate ved fremstilling av et terapeutisk aktivt (6r,7r)-7-((z)-2-(2-amino-tiazol-4-yl)-2-(2-karboksy-prop-2-oksyimino)-acetamido)-3-(1-pyridiniummetyl)cef-3-em-4-karboksylat. |
NO850153A NO850153L (no) | 1978-05-26 | 1985-01-14 | Fremgangsmaate ved fremstilling av cephalosporin-antibiotika |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO850153A NO850153L (no) | 1978-05-26 | 1985-01-14 | Fremgangsmaate ved fremstilling av cephalosporin-antibiotika |
Country Status (27)
Country | Link |
---|---|
US (2) | US4258041A (sl) |
AR (2) | AR228726A1 (sl) |
AT (1) | AT370420B (sl) |
AU (1) | AU524671B2 (sl) |
CA (1) | CA1127633A (sl) |
CH (2) | CH646178A5 (sl) |
DE (1) | DE2921316C2 (sl) |
DK (1) | DK157685C (sl) |
ES (2) | ES480914A1 (sl) |
FI (2) | FI67555C (sl) |
FR (2) | FR2426695A1 (sl) |
HK (1) | HK40183A (sl) |
IE (2) | IE49173B1 (sl) |
IL (3) | IL57400A (sl) |
IT (1) | IT1116198B (sl) |
KE (1) | KE3252A (sl) |
LU (1) | LU81319A1 (sl) |
MY (1) | MY8400017A (sl) |
NL (2) | NL176855C (sl) |
NO (2) | NO155347C (sl) |
NZ (2) | NZ190558A (sl) |
PH (1) | PH16961A (sl) |
PT (2) | PT69669A (sl) |
SE (2) | SE438507B (sl) |
SG (1) | SG58382G (sl) |
SI (2) | SI7911231A8 (sl) |
YU (2) | YU41635B (sl) |
Families Citing this family (112)
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US4237128A (en) * | 1979-04-12 | 1980-12-02 | E. R. Squibb & Sons, Inc. | 7-[2-(2-Amino-4-thiazolyl)-2-[(1-carboxy-1,1-dialkyl)alkoxyimino]acetamido]cephem sulfoxides |
JPS5612397A (en) * | 1979-05-25 | 1981-02-06 | Glaxo Group Ltd | Intermediate for manufacture of cephalosporin antibiotic |
DE3037104C2 (de) * | 1979-10-02 | 1986-04-30 | Glaxo Group Ltd., London | Kristallines Bishydrochlorid von (6R,7R)-7-[(Z)-2-(2-Aminothiazol-4-yl)-2-(2-carboxyprop-2-oximino)acetamido]-3-(1-pyridiniummethyl)ceph-3-em-4-carboxylat |
US4329453A (en) * | 1979-10-02 | 1982-05-11 | Glaxo Group Limited | Cephalosporin antibiotic |
FR2466468A1 (fr) * | 1979-10-02 | 1981-04-10 | Glaxo Group Ltd | Nouvelles cephalosporines, leur procede de preparation et leur application en therapeutique |
US4332800A (en) * | 1979-10-12 | 1982-06-01 | Fujisawa Pharmaceutical Co., Ltd. | Cephem compounds |
US4338313A (en) * | 1979-10-12 | 1982-07-06 | Fujisawa Pharmaceutical Co., Ltd. | Cephem compounds |
DE3006888A1 (de) * | 1980-02-23 | 1981-09-10 | Hoechst Ag, 6000 Frankfurt | Cephalosporinderivate und verfahren zu ihrer herstellung |
FR2476647A2 (fr) * | 1980-02-26 | 1981-08-28 | Roussel Uclaf | Procede de preparation de derives de l'acide 2-(2-amino protege 4-thiazolyl) 2-alkoxyimino acetique isomere syn |
US4252802A (en) * | 1980-03-13 | 1981-02-24 | E. R. Squibb & Sons, Inc. | Hydroxamic acid derivatives of 7-[(2-amino-4-thiazolyl)-oximino] cephalosporins |
GR75706B (sl) * | 1980-06-30 | 1984-08-02 | Sanofi Sa | |
US4443444A (en) * | 1980-08-11 | 1984-04-17 | Fujisawa Pharmaceutical Co., Ltd. | Cephem compounds |
EP0046964B1 (en) * | 1980-08-29 | 1986-08-20 | Fujisawa Pharmaceutical Co., Ltd. | New cephem compounds and processes for preparation thereof |
NZ198350A (en) * | 1980-09-25 | 1985-02-28 | Toyama Chemical Co Ltd | Cephalosporins and intermediates;pharmaceutical compositions |
FR2494276A2 (fr) * | 1980-11-20 | 1982-05-21 | Rhone Poulenc Ind | Nouvelles vinyl-3 cephalosporines, et leur preparation |
US4427677A (en) | 1980-12-31 | 1984-01-24 | Fujisawa Pharmaceutical Co., Ltd. | Cephem compounds |
JPS57144291A (en) * | 1981-03-02 | 1982-09-06 | Ajinomoto Co Inc | Preparation of imidazoledicarboxylic acid derivative |
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DE3118732A1 (de) * | 1981-05-12 | 1982-12-02 | Hoechst Ag, 6000 Frankfurt | Cephalosporinderivate und verfahren zu ihrer herstellung |
GR75487B (sl) * | 1981-06-22 | 1984-07-23 | Fujisawa Pharmaceutical Co | |
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US4024137A (en) * | 1971-05-14 | 1977-05-17 | Glaxo Laboratories Limited | 7β-[2-Etherified oximino-2-(phenyl- or naphthylacetamido)] cephalosporins |
US4033950A (en) * | 1971-05-14 | 1977-07-05 | Glaxo Laboratories Limited | 3-Hydroxymethyl-7β-(2-alkoxy-or benzyloxyimino-2-arylacetamido)ceph-3-em-4-carboxylic acids and salts thereof |
US4064346A (en) * | 1971-05-14 | 1977-12-20 | Glaxo Laboratories Limited | 3-Acetoxymethyl-7β-(2-carboxy-methoxyimino-2-arylacetamido)ceph-3-em-4-carboxylic acids and salts thereof |
US3971778A (en) * | 1972-05-12 | 1976-07-27 | Glaxo Laboratories Limited | Cephalosporins having (α-etherified oximino)acylamido groups at the 7-position |
US4162360A (en) * | 1973-12-21 | 1979-07-24 | Glaxo Laboratories Limited | 3-Carbamoyloxymethyl-7-substituted oximino acetamido cephalosporanic acid derivatives |
US4144392A (en) * | 1973-12-21 | 1979-03-13 | Glaxo Laboratories Limited | Cephalosporins having at position-7 a carboxy substituted α-etherified hydroxyimino-arylacetamido group and at position-3 the residue of a sulphur nucleophile |
GB1496757A (en) | 1973-12-21 | 1978-01-05 | Glaxo Lab Ltd | Cephalosporin derivatives |
US4095021A (en) * | 1973-12-21 | 1978-06-13 | Glaxo Laboratories Limited | 3-Carbamoyloxymethyl or N-methyl-carbamoyloxymethyl-7-[2-carboxymethoxyimino-2-(fur-2-yl or thien-2-yl)acetamido]ceph-3-em-4-carboxylic acids and derivatives thereof |
US4060686A (en) * | 1973-12-21 | 1977-11-29 | Janice Bradshaw | Cephalosporins having a 7-(carboxy substituted α-etherified oximinoarylacetamido) group |
US4032950A (en) * | 1974-12-06 | 1977-06-28 | Hughes Aircraft Company | Liquid phase epitaxial process for growing semi-insulating gaas layers |
DK154939C (da) * | 1974-12-19 | 1989-06-12 | Takeda Chemical Industries Ltd | Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf |
DE2760123C2 (de) * | 1976-01-23 | 1986-04-30 | Roussel-Uclaf, Paris | 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen |
US4165430A (en) * | 1976-03-19 | 1979-08-21 | Glaxo Laboratories Limited | Cephalosporins having a 7-carboxy substituted α-etherified oximinoarylacetamido) group |
US4166115A (en) * | 1976-04-12 | 1979-08-28 | Fujisawa Pharmaceutical Co., Ltd. | Syn 7-oxoimino substituted derivatives of cephalosporanic acid |
JPS52125188A (en) | 1976-04-14 | 1977-10-20 | Takeda Chem Ind Ltd | Cephalosporin derivatives and their preparation |
ZA781502B (en) | 1977-03-14 | 1979-09-26 | Fujisawa Pharmaceutical Co | New cephem and cepham compounds and processes for preparation thereof |
FR2384782A1 (fr) | 1977-03-25 | 1978-10-20 | Roussel Uclaf | Nouvelles oximes derivees de l'acide 3-acetoxymethyl 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments |
DE2716677C2 (de) | 1977-04-15 | 1985-10-10 | Hoechst Ag, 6230 Frankfurt | Cephemderivate und Verfahren zu ihrer Herstellung |
HU184680B (en) | 1977-04-02 | 1984-09-28 | Hoechst Ag | Process for producing ceph-3-eme-4-carboxylic acid derivatives containing amino-thiazolyl group in the side chain |
DE2714880A1 (de) * | 1977-04-02 | 1978-10-26 | Hoechst Ag | Cephemderivate und verfahren zu ihrer herstellung |
GB1602725A (en) | 1977-04-27 | 1981-11-18 | Glaxo Operations Ltd | 7-(a-oxyiminoacetamido)-ceph-3-em-4-carboxylic acid derivatives |
AR228726A1 (es) * | 1978-05-26 | 1983-04-15 | Glaxo Group Ltd | Procedimiento para la preparacion del antibiotico(6r,7r)-7-((z)-2-(2-aminotiazol-4-il)-2-(2-carboxiprop-2-oxiimino)acetamido)-3-(1-piridiniometil)cef-3-em-4-carboxilato |
US4237128A (en) * | 1979-04-12 | 1980-12-02 | E. R. Squibb & Sons, Inc. | 7-[2-(2-Amino-4-thiazolyl)-2-[(1-carboxy-1,1-dialkyl)alkoxyimino]acetamido]cephem sulfoxides |
US4394503A (en) * | 1981-12-07 | 1983-07-19 | Bristol-Myers Company | Cephalosporin derivatives |
-
1979
- 1979-05-24 AR AR276665A patent/AR228726A1/es active
- 1979-05-24 AR AR276664A patent/AR229883A1/es active
- 1979-05-25 IL IL57400A patent/IL57400A/xx unknown
- 1979-05-25 IL IL59793A patent/IL59793A/xx unknown
- 1979-05-25 YU YU1231/79A patent/YU41635B/xx unknown
- 1979-05-25 CH CH491579A patent/CH646178A5/de not_active IP Right Cessation
- 1979-05-25 NZ NZ190558A patent/NZ190558A/xx unknown
- 1979-05-25 CH CH1707/80A patent/CH649556A5/de not_active IP Right Cessation
- 1979-05-25 CA CA328,413A patent/CA1127633A/en not_active Expired
- 1979-05-25 DK DK216779A patent/DK157685C/da active
- 1979-05-25 SI SI7911231A patent/SI7911231A8/sl unknown
- 1979-05-25 NO NO791731A patent/NO155347C/no unknown
- 1979-05-25 FI FI791678A patent/FI67555C/fi not_active IP Right Cessation
- 1979-05-25 PT PT69669A patent/PT69669A/pt unknown
- 1979-05-25 NL NLAANVRAGE7904122,A patent/NL176855C/xx not_active IP Right Cessation
- 1979-05-25 PH PH22562A patent/PH16961A/en unknown
- 1979-05-25 SE SE7904576A patent/SE438507B/sv not_active IP Right Cessation
- 1979-05-25 ES ES480914A patent/ES480914A1/es not_active Expired
- 1979-05-25 DE DE2921316A patent/DE2921316C2/de not_active Expired
- 1979-05-25 LU LU81319A patent/LU81319A1/xx unknown
- 1979-05-25 ES ES480915A patent/ES480915A1/es not_active Expired
- 1979-05-25 PT PT69670A patent/PT69670A/pt unknown
- 1979-05-25 AU AU47422/79A patent/AU524671B2/en not_active Expired
- 1979-05-25 US US06/042,594 patent/US4258041A/en not_active Expired - Lifetime
- 1979-05-25 IT IT7949179A patent/IT1116198B/it active Protection Beyond IP Right Term
- 1979-05-28 FR FR7913531A patent/FR2426695A1/fr active Granted
- 1979-08-08 IE IE2453/80A patent/IE49173B1/en unknown
- 1979-08-08 IE IE1025/79A patent/IE49172B1/en not_active IP Right Cessation
-
1980
- 1980-03-06 NL NL8001348A patent/NL8001348A/nl not_active Application Discontinuation
- 1980-04-01 NZ NZ193326A patent/NZ193326A/xx unknown
- 1980-04-09 FR FR8007929A patent/FR2445835A1/fr active Granted
- 1980-04-09 IL IL59793A patent/IL59793A0/xx unknown
- 1980-05-19 FI FI801609A patent/FI67705C/fi not_active IP Right Cessation
-
1981
- 1981-05-27 AT AT0239281A patent/AT370420B/de not_active IP Right Cessation
-
1982
- 1982-09-13 US US06/417,656 patent/US4600772A/en not_active Expired - Lifetime
- 1982-10-05 YU YU2234/82A patent/YU43097B/xx unknown
- 1982-10-05 SI SI8212234A patent/SI8212234A8/sl unknown
- 1982-11-16 SG SG583/82A patent/SG58382G/en unknown
- 1982-11-26 KE KE3252A patent/KE3252A/xx unknown
-
1983
- 1983-10-13 HK HK401/83A patent/HK40183A/xx not_active IP Right Cessation
-
1984
- 1984-05-28 SE SE8402887A patent/SE8402887L/xx not_active Application Discontinuation
- 1984-12-30 MY MY17/84A patent/MY8400017A/xx unknown
-
1985
- 1985-01-14 NO NO850153A patent/NO850153L/no unknown
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