NL8301949A - Amidines en werkwijze voor het bereiden daarvan. - Google Patents

Amidines en werkwijze voor het bereiden daarvan. Download PDF

Info

Publication number
NL8301949A
NL8301949A NL8301949A NL8301949A NL8301949A NL 8301949 A NL8301949 A NL 8301949A NL 8301949 A NL8301949 A NL 8301949A NL 8301949 A NL8301949 A NL 8301949A NL 8301949 A NL8301949 A NL 8301949A
Authority
NL
Netherlands
Prior art keywords
amino
compound according
compound
formula
methoxymitosane
Prior art date
Application number
NL8301949A
Other languages
English (en)
Dutch (nl)
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of NL8301949A publication Critical patent/NL8301949A/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NL8301949A 1982-06-04 1983-06-01 Amidines en werkwijze voor het bereiden daarvan. NL8301949A (nl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US38514982A 1982-06-04 1982-06-04
US38514982 1982-06-04
US06/492,903 US4487769A (en) 1982-06-04 1983-05-09 Amidines
US49290383 1983-05-09

Publications (1)

Publication Number Publication Date
NL8301949A true NL8301949A (nl) 1984-01-02

Family

ID=27010906

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8301949A NL8301949A (nl) 1982-06-04 1983-06-01 Amidines en werkwijze voor het bereiden daarvan.

Country Status (27)

Country Link
US (1) US4487769A (fr)
KR (1) KR870000932B1 (fr)
AR (1) AR241438A1 (fr)
AT (1) AT394853B (fr)
AU (1) AU571179B2 (fr)
CA (1) CA1230333A (fr)
CH (1) CH657856A5 (fr)
DD (1) DD210275A5 (fr)
DE (1) DE3319992A1 (fr)
DK (2) DK161023C (fr)
ES (3) ES522948A0 (fr)
FI (1) FI78700C (fr)
FR (1) FR2528048B1 (fr)
GB (1) GB2121796B (fr)
GR (1) GR78277B (fr)
HU (1) HU198936B (fr)
IE (1) IE56107B1 (fr)
IL (1) IL68852A0 (fr)
IT (1) IT1206452B (fr)
LU (1) LU84843A1 (fr)
NL (1) NL8301949A (fr)
NO (1) NO161676C (fr)
NZ (1) NZ204352A (fr)
OA (1) OA07452A (fr)
PT (1) PT76810B (fr)
SE (1) SE455504B (fr)
YU (2) YU42866B (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ206932A (en) * 1983-02-07 1987-08-31 University Patents Inc Certain 6-(heterocyclyl or amino) mitosanes and pharmaceutical compositions
US4803212A (en) * 1983-04-11 1989-02-07 Bristol-Myers Company Amino disulfides
US4579737A (en) * 1983-05-09 1986-04-01 Bristol-Myers Company Bis-amidines
US4642352A (en) * 1983-12-23 1987-02-10 Bristol-Myers Company Acylamino mitosanes
US4814445A (en) * 1984-09-04 1989-03-21 Bristol-Myers Company Process for preparing mitomycin analogs
AU581673B2 (en) * 1984-09-04 1989-03-02 Bristol-Myers Company Substituted 7-oxomitosanes
JPS61176590A (ja) * 1985-01-31 1986-08-08 Kyowa Hakko Kogyo Co Ltd ７−ｎ−アミノメチレンマイトマイシン誘導体、製造法及び抗腫瘍剤
US4639528A (en) * 1985-02-21 1987-01-27 Bristol-Myers Company Crystalline form of 7-(dimethylaminomethylene-amino-9a-methoxymitosane
AT396688B (de) * 1985-02-21 1993-11-25 Bristol Myers Squibb Co Verfahren zur herstellung von kristallinem
ZA86308B (en) * 1985-02-25 1986-11-26 Bristol Myers Co In-vial deposition of 7-(dimethylaminomethylene)amino-9a-methoxy-mitosane
US4652644A (en) * 1985-04-29 1987-03-24 Bristol-Myers Company Process for preparation of N7 -amidino substituted mitomycin C derivatives
JPH066592B2 (ja) * 1986-04-18 1994-01-26 協和醗酵工業株式会社 マイトマイシン誘導体
US4791113A (en) * 1986-05-14 1988-12-13 Kyowa Hakko Kogyo Kabushiki Kaisha Mitomycin derivatives as antileukemia agents
JPS6354380A (ja) * 1986-08-26 1988-03-08 Kyowa Hakko Kogyo Co Ltd マイトマイシン誘導体
JPS63150282A (ja) * 1986-12-13 1988-06-22 Kyowa Hakko Kogyo Co Ltd マイトマイシン誘導体
IL86665A0 (en) * 1987-06-12 1988-11-30 Bristol Myers Co Mitomycin analogs
IL89203A0 (en) * 1988-02-11 1989-09-10 Univ Houston 7-substituted hydrazine mitomycin analogs and pharmaceutical compositions containing them

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3660578A (en) * 1957-04-06 1972-05-02 Kyowa Hakko Kogyo Kk Mitomycin c
US3121084A (en) * 1962-09-17 1964-02-11 Du Pont Selected n, n, n'-trisubstituted amidines and their preparation by reaction of compounds with-nh2 groups with amide acetals
NL129868C (fr) * 1963-06-07
DE1570029A1 (de) * 1964-07-09 1970-04-09 Kyowa Hakko Kogyo Kk Verfahren zur Herstellung von Mitosanverbindungen
US3420846A (en) * 1964-08-25 1969-01-07 Kyowa Hakko Kogyo Kk 7-substituted mitomycin a
US3332944A (en) * 1964-11-02 1967-07-25 American Cyanamid Co Antibiotic derivatives of mitomycins a, b, c and porfiromycin
JPS5439098A (en) * 1977-08-31 1979-03-24 Kyowa Hakko Kogyo Co Ltd Mitomycin c derivatives
US4268676A (en) * 1979-12-05 1981-05-19 University Patents, Inc. Mitomycin analogs
NZ206932A (en) * 1983-02-07 1987-08-31 University Patents Inc Certain 6-(heterocyclyl or amino) mitosanes and pharmaceutical compositions
US4803212A (en) * 1983-04-11 1989-02-07 Bristol-Myers Company Amino disulfides
JPS6073085A (ja) * 1983-09-28 1985-04-25 Matsushita Refrig Co ロ−タリ−コンプレツサ
US4642352A (en) * 1983-12-23 1987-02-10 Bristol-Myers Company Acylamino mitosanes

Also Published As

Publication number Publication date
HU198936B (en) 1989-12-28
DK161023B (da) 1991-05-21
FI831972A0 (fi) 1983-06-01
ES529584A0 (es) 1985-04-16
FR2528048A1 (fr) 1983-12-09
OA07452A (fr) 1984-03-31
ES8407493A1 (es) 1984-10-01
DK253083A (da) 1983-12-05
ATA206483A (de) 1991-12-15
ES8504198A1 (es) 1985-04-16
PT76810B (en) 1986-04-09
SE8303160L (sv) 1984-01-27
US4487769A (en) 1984-12-11
AT394853B (de) 1992-07-10
IT1206452B (it) 1989-04-27
GR78277B (fr) 1984-09-26
IE56107B1 (en) 1991-04-24
DK162167C (da) 1992-02-24
AU571179B2 (en) 1988-04-14
CA1230333A (fr) 1987-12-15
AU1501483A (en) 1983-12-08
YU124183A (en) 1986-06-30
DK162167B (da) 1991-09-23
NO161676C (no) 1989-09-13
DD210275A5 (de) 1984-06-06
IT8321461A0 (it) 1983-06-03
GB2121796B (en) 1986-03-12
FR2528048B1 (fr) 1986-12-12
LU84843A1 (fr) 1984-03-07
DE3319992C2 (fr) 1991-11-21
DE3319992A1 (de) 1983-12-08
SE455504B (sv) 1988-07-18
NO161676B (no) 1989-06-05
YU16486A (en) 1986-12-31
GB2121796A (en) 1984-01-04
ES529585A0 (es) 1985-04-16
ES8504199A1 (es) 1985-04-16
DK281490D0 (da) 1990-11-27
NO832022L (no) 1983-12-05
IL68852A0 (en) 1983-10-31
KR870000932B1 (ko) 1987-05-11
PT76810A (en) 1983-07-01
NZ204352A (en) 1987-07-31
SE8303160D0 (sv) 1983-06-03
ES522948A0 (es) 1984-10-01
FI78700B (fi) 1989-05-31
YU42866B (en) 1988-12-31
FI78700C (fi) 1989-09-11
FI831972L (fi) 1983-12-05
KR840005143A (ko) 1984-11-03
CH657856A5 (de) 1986-09-30
IE831320L (en) 1983-12-04
YU43427B (en) 1989-06-30
GB8315205D0 (en) 1983-07-06
DK253083D0 (da) 1983-06-03
AR241438A1 (es) 1992-07-31
DK161023C (da) 1991-10-28
DK281490A (da) 1990-11-27

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Legal Events

Date Code Title Description
BT A notification was added to the application dossier and made available to the public
A85 Still pending on 85-01-01
BT A notification was added to the application dossier and made available to the public
DNT Communications of changes of names of applicants whose applications have been laid open to public inspection

Free format text: BRISTOL-MYERS SQUIBB COMPANY

BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
BV The patent application has lapsed