NL193663C - Werkwijze en kit voor het detecteren van een specifiek nucleïnezuur in een monster. - Google Patents

Werkwijze en kit voor het detecteren van een specifiek nucleïnezuur in een monster. Download PDF

Info

Publication number
NL193663C
NL193663C NL8500424A NL8500424A NL193663C NL 193663 C NL193663 C NL 193663C NL 8500424 A NL8500424 A NL 8500424A NL 8500424 A NL8500424 A NL 8500424A NL 193663 C NL193663 C NL 193663C
Authority
NL
Netherlands
Prior art keywords
nucleic acid
nucleic acids
series
detected
dna
Prior art date
Application number
NL8500424A
Other languages
English (en)
Dutch (nl)
Other versions
NL193663B (nl
NL8500424A (nl
Original Assignee
Sangtec Medical Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sangtec Medical Ab filed Critical Sangtec Medical Ab
Publication of NL8500424A publication Critical patent/NL8500424A/nl
Publication of NL193663B publication Critical patent/NL193663B/xx
Application granted granted Critical
Publication of NL193663C publication Critical patent/NL193663C/nl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • C12Q1/705Specific hybridization probes for herpetoviridae, e.g. herpes simplex, varicella zoster
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • C12Q1/682Signal amplification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6834Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
NL8500424A 1984-02-17 1985-02-14 Werkwijze en kit voor het detecteren van een specifiek nucleïnezuur in een monster. NL193663C (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI840655 1984-02-17
FI840655A FI71768C (fi) 1984-02-17 1984-02-17 Foerbaettrade nykleinsyrareagenser och foerfarande foer deras framstaellning.

Publications (3)

Publication Number Publication Date
NL8500424A NL8500424A (nl) 1985-09-16
NL193663B NL193663B (nl) 2000-02-01
NL193663C true NL193663C (nl) 2000-06-06

Family

ID=8518568

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8500424A NL193663C (nl) 1984-02-17 1985-02-14 Werkwijze en kit voor het detecteren van een specifiek nucleïnezuur in een monster.

Country Status (22)

Country Link
US (1) US4731325A (fr)
JP (1) JPS60188100A (fr)
AT (1) AT394578B (fr)
AU (1) AU577568B2 (fr)
BE (1) BE901671A (fr)
CA (1) CA1248895A (fr)
CH (1) CH671778A5 (fr)
DE (1) DE3505287C2 (fr)
DK (1) DK174675B1 (fr)
FI (1) FI71768C (fr)
FR (1) FR2559783B1 (fr)
GB (1) GB2156074B (fr)
HU (1) HU194938B (fr)
IE (1) IE57652B1 (fr)
IT (1) IT1183184B (fr)
LU (1) LU85768A1 (fr)
NL (1) NL193663C (fr)
NO (1) NO166543C (fr)
RO (1) RO92633B (fr)
SE (1) SE463103B (fr)
SU (1) SU1523053A3 (fr)
ZA (1) ZA85511B (fr)

Families Citing this family (151)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1260372A (fr) * 1984-04-27 1989-09-26 Elazar Rabbani Methode d'hybridation pour la detection de materiaux genetiques
US4725536A (en) * 1985-09-19 1988-02-16 Genetics Institute, Inc. Reagent polynucleotide complex with multiple target binding regions, and kit and methods
US4876187A (en) * 1985-12-05 1989-10-24 Meiogenics, Inc. Nucleic acid compositions with scissile linkage useful for detecting nucleic acid sequences
US4910300A (en) * 1985-12-11 1990-03-20 Chiron Corporation Method for making nucleic acid probes
US4868105A (en) * 1985-12-11 1989-09-19 Chiron Corporation Solution phase nucleic acid sandwich assay
US4882269A (en) * 1985-12-13 1989-11-21 Princeton University Amplified hybridization assay
FI76119C (fi) * 1986-02-27 1988-09-09 Orion Yhtymae Oy Kvantitativ bestaemning av nukleinsyramolekyler och reagensfoerpackning som anvaends vid foerfarandet.
US4925785A (en) * 1986-03-07 1990-05-15 Biotechnica Diagnostics, Inc. Nucleic acid hybridization assays
CA1341065C (fr) * 1986-05-01 2000-08-01 J. Thomas Grayston Detection d'une souche unique de chlamydia associee aux maladies respiratoires aigues
US5281518A (en) * 1986-05-01 1994-01-25 Washington Research Foundation Detection of a unique chlamydia strain associated with acute respiratory disease
US6270961B1 (en) * 1987-04-01 2001-08-07 Hyseq, Inc. Methods and apparatus for DNA sequencing and DNA identification
US5202231A (en) * 1987-04-01 1993-04-13 Drmanac Radoje T Method of sequencing of genomes by hybridization of oligonucleotide probes
US5124246A (en) * 1987-10-15 1992-06-23 Chiron Corporation Nucleic acid multimers and amplified nucleic acid hybridization assays using same
CA1339351C (fr) * 1987-10-15 1997-08-26 Michael S. Urdea Multimeres d'acide nucleique et essais d'hybridation amplifiee d'acide nucleique
US5359100A (en) * 1987-10-15 1994-10-25 Chiron Corporation Bifunctional blocked phosphoramidites useful in making nucleic acid mutimers
AU622426B2 (en) * 1987-12-11 1992-04-09 Abbott Laboratories Assay using template-dependent nucleic acid probe reorganization
GB8810400D0 (en) * 1988-05-03 1988-06-08 Southern E Analysing polynucleotide sequences
US5700637A (en) * 1988-05-03 1997-12-23 Isis Innovation Limited Apparatus and method for analyzing polynucleotide sequences and method of generating oligonucleotide arrays
US7811751B2 (en) * 1988-05-03 2010-10-12 Oxford Gene Technology Limited Analysing polynucleotide sequences
US6054270A (en) * 1988-05-03 2000-04-25 Oxford Gene Technology Limited Analying polynucleotide sequences
JP2801051B2 (ja) * 1988-06-24 1998-09-21 アムジエン・インコーポレーテツド 核酸塩基配列を検出するための方法及び試薬
US5185243A (en) * 1988-08-25 1993-02-09 Syntex (U.S.A.) Inc. Method for detection of specific nucleic acid sequences
CA2026573A1 (fr) * 1989-02-03 1990-08-04 John B. Findlay Article pour les essais de detection d'un acide nucleique predetermine
US6551784B2 (en) 1989-06-07 2003-04-22 Affymetrix Inc Method of comparing nucleic acid sequences
US6416952B1 (en) 1989-06-07 2002-07-09 Affymetrix, Inc. Photolithographic and other means for manufacturing arrays
US6346413B1 (en) 1989-06-07 2002-02-12 Affymetrix, Inc. Polymer arrays
US5424186A (en) 1989-06-07 1995-06-13 Affymax Technologies N.V. Very large scale immobilized polymer synthesis
US5143854A (en) * 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US6309822B1 (en) 1989-06-07 2001-10-30 Affymetrix, Inc. Method for comparing copy number of nucleic acid sequences
US6040138A (en) 1995-09-15 2000-03-21 Affymetrix, Inc. Expression monitoring by hybridization to high density oligonucleotide arrays
US5744101A (en) 1989-06-07 1998-04-28 Affymax Technologies N.V. Photolabile nucleoside protecting groups
US6406844B1 (en) 1989-06-07 2002-06-18 Affymetrix, Inc. Very large scale immobilized polymer synthesis
US5925525A (en) * 1989-06-07 1999-07-20 Affymetrix, Inc. Method of identifying nucleotide differences
US5800992A (en) * 1989-06-07 1998-09-01 Fodor; Stephen P.A. Method of detecting nucleic acids
US6955915B2 (en) * 1989-06-07 2005-10-18 Affymetrix, Inc. Apparatus comprising polymers
US6919211B1 (en) * 1989-06-07 2005-07-19 Affymetrix, Inc. Polypeptide arrays
US5232829A (en) * 1989-09-29 1993-08-03 Hoffmann-La Roche Inc. Detection of chlamydia trachomatis by polymerase chain reaction using biotin labelled lina primers and capture probes
US6506558B1 (en) 1990-03-07 2003-01-14 Affymetrix Inc. Very large scale immobilized polymer synthesis
CA2039517C (fr) * 1990-04-03 2006-11-07 David Segev Amplification du signal d'une sonde d'adn
US5071962A (en) * 1990-05-31 1991-12-10 The United State Of America As Represented By The Department Of Health And Human Services Nucleotide, deduced amino acid sequence, isolation and purification of heat-shock chlamydial proteins
EP0466367B1 (fr) * 1990-06-28 1995-08-23 Wakunaga Seiyaku Kabushiki Kaisha Méthode pour la détection d'acides nucléiques
US5645994A (en) * 1990-07-05 1997-07-08 University Of Utah Research Foundation Method and compositions for identification of species in a sample using type II topoisomerase sequences
GB9020621D0 (en) * 1990-09-21 1990-10-31 Imp Cancer Res Tech Identification of organisms
GB2262987A (en) * 1990-09-21 1993-07-07 Imp Cancer Res Tech Identification of organisms
DE69132843T2 (de) * 1990-12-06 2002-09-12 Affymetrix Inc N D Ges D Staat Identifizierung von Nukleinsäuren in Proben
US5437976A (en) * 1991-08-08 1995-08-01 Arizona Board Of Regents, The University Of Arizona Multi-domain DNA ligands bound to a solid matrix for protein and nucleic acid affinity chromatography and processing of solid-phase DNA
US6051380A (en) * 1993-11-01 2000-04-18 Nanogen, Inc. Methods and procedures for molecular biological analysis and diagnostics
US6048690A (en) * 1991-11-07 2000-04-11 Nanogen, Inc. Methods for electronic fluorescent perturbation for analysis and electronic perturbation catalysis for synthesis
US5632957A (en) 1993-11-01 1997-05-27 Nanogen Molecular biological diagnostic systems including electrodes
US6017696A (en) 1993-11-01 2000-01-25 Nanogen, Inc. Methods for electronic stringency control for molecular biological analysis and diagnostics
US5605662A (en) * 1993-11-01 1997-02-25 Nanogen, Inc. Active programmable electronic devices for molecular biological analysis and diagnostics
US5849486A (en) 1993-11-01 1998-12-15 Nanogen, Inc. Methods for hybridization analysis utilizing electrically controlled hybridization
US6569382B1 (en) * 1991-11-07 2003-05-27 Nanogen, Inc. Methods apparatus for the electronic, homogeneous assembly and fabrication of devices
US6652808B1 (en) * 1991-11-07 2003-11-25 Nanotronics, Inc. Methods for the electronic assembly and fabrication of devices
US5556961A (en) * 1991-11-15 1996-09-17 Foote; Robert S. Nucleosides with 5'-O-photolabile protecting groups
US6849462B1 (en) 1991-11-22 2005-02-01 Affymetrix, Inc. Combinatorial strategies for polymer synthesis
DE69233331T3 (de) 1991-11-22 2007-08-30 Affymetrix, Inc., Santa Clara Kombinatorische Strategien zur Polymersynthese
US6943034B1 (en) * 1991-11-22 2005-09-13 Affymetrix, Inc. Combinatorial strategies for polymer synthesis
US6468740B1 (en) 1992-11-05 2002-10-22 Affymetrix, Inc. Cyclic and substituted immobilized molecular synthesis
WO1993013221A1 (fr) * 1991-12-23 1993-07-08 Chiron Corporation Sondes pour chlamydiae utilisees dans des methodes d'hybridation en sandwich en phase de solution
CA2124796A1 (fr) * 1991-12-23 1993-07-08 Chiron Diagnostics Corporation Sondes a cmv pour utilisation dans des essais d'hybridation en sandwich en phase liquide
US5583211A (en) * 1992-10-29 1996-12-10 Beckman Instruments, Inc. Surface activated organic polymers useful for location - specific attachment of nucleic acids, peptides, proteins and oligosaccharides
US7713528B1 (en) 1993-02-18 2010-05-11 Enzo Therapeutics, Inc. Method for in vivo delivery of active compounds using reagent conjugate
WO1995003401A1 (fr) * 1993-07-23 1995-02-02 Hyseq, Inc. Procede de detection d'organismes inconnus
FR2710075B1 (fr) * 1993-09-15 1995-10-27 Bio Merieux Réactif et procédé pour la détection d'une séquence nucléotidique avec amplification de signal.
US6319472B1 (en) 1993-11-01 2001-11-20 Nanogen, Inc. System including functionally separated regions in electrophoretic system
US7101661B1 (en) 1993-11-01 2006-09-05 Nanogen, Inc. Apparatus for active programmable matrix devices
US6254827B1 (en) 1993-11-01 2001-07-03 Nanogen, Inc. Methods for fabricating multi-component devices for molecular biological analysis and diagnostics
US6331274B1 (en) 1993-11-01 2001-12-18 Nanogen, Inc. Advanced active circuits and devices for molecular biological analysis and diagnostics
US6068818A (en) 1993-11-01 2000-05-30 Nanogen, Inc. Multicomponent devices for molecular biological analysis and diagnostics
US7582421B2 (en) * 1993-11-01 2009-09-01 Nanogen, Inc. Methods for determination of single nucleic acid polymorphisms using a bioelectronic microchip
US7314708B1 (en) 1998-08-04 2008-01-01 Nanogen, Inc. Method and apparatus for electronic synthesis of molecular structures
US6287517B1 (en) 1993-11-01 2001-09-11 Nanogen, Inc. Laminated assembly for active bioelectronic devices
US6375899B1 (en) 1993-11-01 2002-04-23 Nanogen, Inc. Electrophoretic buss for transport of charged materials in a multi-chamber system
US6638482B1 (en) 1993-11-01 2003-10-28 Nanogen, Inc. Reconfigurable detection and analysis apparatus and method
US6309602B1 (en) 1993-11-01 2001-10-30 Nanogen, Inc. Stacked, reconfigurable system for electrophoretic transport of charged materials
US7172864B1 (en) 1993-11-01 2007-02-06 Nanogen Methods for electronically-controlled enzymatic reactions
US20040077074A1 (en) * 1993-11-01 2004-04-22 Nanogen, Inc. Multi-chambered analysis device
US6225059B1 (en) 1993-11-01 2001-05-01 Nanogen, Inc. Advanced active electronic devices including collection electrodes for molecular biological analysis and diagnostics
US6726880B1 (en) 1993-11-01 2004-04-27 Nanogen, Inc. Electronic device for performing active biological operations and method of using same
US6315953B1 (en) 1993-11-01 2001-11-13 Nanogen, Inc. Devices for molecular biological analysis and diagnostics including waveguides
US6287850B1 (en) * 1995-06-07 2001-09-11 Affymetrix, Inc. Bioarray chip reaction apparatus and its manufacture
DE69527585T2 (de) * 1994-06-08 2003-04-03 Affymetrix Inc Verfahren und Vorrichtung zum Verpacken von Chips
US5807522A (en) * 1994-06-17 1998-09-15 The Board Of Trustees Of The Leland Stanford Junior University Methods for fabricating microarrays of biological samples
US7323298B1 (en) * 1994-06-17 2008-01-29 The Board Of Trustees Of The Leland Stanford Junior University Microarray for determining the relative abundances of polynuceotide sequences
US7378236B1 (en) 1994-06-17 2008-05-27 The Board Of Trustees Of The Leland Stanford Junior University Method for analyzing gene expression patterns
US6306657B1 (en) * 1994-06-28 2001-10-23 Kalyx Biosciences, Inc. Polynucleotide probe and kit for amplifying signal detection in hybridization assays
US6403367B1 (en) 1994-07-07 2002-06-11 Nanogen, Inc. Integrated portable biological detection system
US7857957B2 (en) * 1994-07-07 2010-12-28 Gamida For Life B.V. Integrated portable biological detection system
US6121048A (en) * 1994-10-18 2000-09-19 Zaffaroni; Alejandro C. Method of conducting a plurality of reactions
US8236493B2 (en) * 1994-10-21 2012-08-07 Affymetrix, Inc. Methods of enzymatic discrimination enhancement and surface-bound double-stranded DNA
US6720149B1 (en) * 1995-06-07 2004-04-13 Affymetrix, Inc. Methods for concurrently processing multiple biological chip assays
US20040086917A1 (en) * 1995-09-27 2004-05-06 Nanogen, Inc. Methods for electronic fluorescent perturbation for analysis and electronic perturbation catalysis for synthesis
EP0880598A4 (fr) 1996-01-23 2005-02-23 Affymetrix Inc Evaluation rapide de difference d'abondance d'acides nucleiques, avec un systeme d'oligonucleotides haute densite
US6706473B1 (en) 1996-12-06 2004-03-16 Nanogen, Inc. Systems and devices for photoelectrophoretic transport and hybridization of oligonucleotides
US20020042048A1 (en) 1997-01-16 2002-04-11 Radoje Drmanac Methods and compositions for detection or quantification of nucleic acid species
US6309824B1 (en) 1997-01-16 2001-10-30 Hyseq, Inc. Methods for analyzing a target nucleic acid using immobilized heterogeneous mixtures of oligonucleotide probes
US6297006B1 (en) 1997-01-16 2001-10-02 Hyseq, Inc. Methods for sequencing repetitive sequences and for determining the order of sequence subfragments
US6326489B1 (en) 1997-08-05 2001-12-04 Howard Hughes Medical Institute Surface-bound, bimolecular, double-stranded DNA arrays
DE19741715A1 (de) 1997-09-22 1999-03-25 Hoechst Ag Pentopyranosyl-Nucleosid, seine Herstellung und Verwendung
US6511803B1 (en) 1997-10-10 2003-01-28 President And Fellows Of Harvard College Replica amplification of nucleic acid arrays
US6485944B1 (en) 1997-10-10 2002-11-26 President And Fellows Of Harvard College Replica amplification of nucleic acid arrays
AU737174B2 (en) 1997-10-10 2001-08-09 President & Fellows Of Harvard College Replica amplification of nucleic acid arrays
EP1021558A1 (fr) 1997-10-10 2000-07-26 President And Fellows Of Harvard College Ensembles de proteines d'adn double brin liees a la surface
ES2246546T3 (es) * 1997-12-12 2006-02-16 Digene Corporation Valoracion de enfermedades relacionadas con el virus de papiloma humano.
US6355419B1 (en) 1998-04-27 2002-03-12 Hyseq, Inc. Preparation of pools of nucleic acids based on representation in a sample
US6232067B1 (en) 1998-08-17 2001-05-15 The Perkin-Elmer Corporation Adapter directed expression analysis
US6545264B1 (en) 1998-10-30 2003-04-08 Affymetrix, Inc. Systems and methods for high performance scanning
US7612020B2 (en) * 1998-12-28 2009-11-03 Illumina, Inc. Composite arrays utilizing microspheres with a hybridization chamber
AU4025300A (en) * 1999-03-24 2000-10-09 Packard Bioscience Company Continuous porous matrix arrays
AU4058500A (en) * 1999-03-30 2000-10-16 Nanogen, Inc. Single nucleotide polymorphic discrimination by electronic dot blot assay on semiconductor microchips
EP1173878B1 (fr) 1999-04-27 2011-04-06 Bio-Rad Laboratories, Inc. Sondes pour spectrometre d'ions en phase gazeuse
US20030096321A1 (en) * 1999-05-19 2003-05-22 Jose Remacle Method for the identification and/or the quantification of a target compound obtained from a biological sample upon chips
EP1054259A1 (fr) * 1999-05-19 2000-11-22 Remacle, José Procédé d'identification de composé cible
US6465183B2 (en) * 1999-07-01 2002-10-15 Agilent Technologies, Inc. Multidentate arrays
JP2001017166A (ja) * 1999-07-02 2001-01-23 Fuji Photo Film Co Ltd Dnaチップ、dnaチップの検定キットおよびdnaチップの検定法
US6428957B1 (en) 1999-11-08 2002-08-06 Agilent Technologies, Inc. Systems tools and methods of assaying biological materials using spatially-addressable arrays
US6235483B1 (en) 2000-01-31 2001-05-22 Agilent Technologies, Inc. Methods and kits for indirect labeling of nucleic acids
US8076063B2 (en) 2000-02-07 2011-12-13 Illumina, Inc. Multiplexed methylation detection methods
US7582420B2 (en) 2001-07-12 2009-09-01 Illumina, Inc. Multiplex nucleic acid reactions
US7955794B2 (en) 2000-09-21 2011-06-07 Illumina, Inc. Multiplex nucleic acid reactions
US6455007B1 (en) * 2000-06-13 2002-09-24 Symyx Technologies, Inc. Apparatus and method for testing compositions in contact with a porous medium
US7601497B2 (en) 2000-06-15 2009-10-13 Qiagen Gaithersburg, Inc. Detection of nucleic acids by target-specific hybrid capture method
US7439016B1 (en) * 2000-06-15 2008-10-21 Digene Corporation Detection of nucleic acids by type-specific hybrid capture method
US6905816B2 (en) 2000-11-27 2005-06-14 Intelligent Medical Devices, Inc. Clinically intelligent diagnostic devices and methods
DK1373573T3 (da) * 2001-03-09 2014-01-20 Trovagene Inc Konjugatsonder og optisk detektion af analytter
EP1481076A4 (fr) 2001-07-12 2005-05-11 Illumina Inc Reactions multiplex d'acides nucleiques
US6893822B2 (en) 2001-07-19 2005-05-17 Nanogen Recognomics Gmbh Enzymatic modification of a nucleic acid-synthetic binding unit conjugate
US7601493B2 (en) * 2002-07-26 2009-10-13 Nanogen, Inc. Methods and apparatus for screening and detecting multiple genetic mutations
US20040241659A1 (en) * 2003-05-30 2004-12-02 Applera Corporation Apparatus and method for hybridization and SPR detection
US7622281B2 (en) 2004-05-20 2009-11-24 The Board Of Trustees Of The Leland Stanford Junior University Methods and compositions for clonal amplification of nucleic acid
US7828954B2 (en) * 2004-09-21 2010-11-09 Gamida For Life B.V. Electrode based patterning of thin film self-assembled nanoparticles
US7314542B2 (en) * 2004-09-23 2008-01-01 Nanogen, Inc. Methods and materials for optimization of electronic transportation and hybridization reactions
US20060246576A1 (en) 2005-04-06 2006-11-02 Affymetrix, Inc. Fluidic system and method for processing biological microarrays in personal instrumentation
JP5187847B2 (ja) 2005-05-06 2013-04-24 ジェン−プローブ・インコーポレーテッド 核酸標的の捕獲方法
WO2007070553A2 (fr) * 2005-12-12 2007-06-21 The Johns Hopkins University Reseaux a double quadrillage et multiquadrillage et procedes correspondants
EP1971690B1 (fr) 2005-12-28 2018-10-17 Translational Therapeutics, Inc. Therapeutique reposant sur une perturbation de traduction
WO2008060369A2 (fr) 2006-09-29 2008-05-22 Translational Therapeutics, Inc. Diagnostics à base de régulon eif4e
US20080003667A1 (en) * 2006-05-19 2008-01-03 Affymetrix, Inc. Consumable elements for use with fluid processing and detection systems
EP1912067A1 (fr) * 2006-10-12 2008-04-16 Eppendorf Array Technologies S.A. Procédé de quantification d'un composé cible issu d'un échantillon biologique à l'aide de puces à microreseau
US9938641B2 (en) * 2006-12-18 2018-04-10 Fluidigm Corporation Selection of aptamers based on geometry
WO2008085777A2 (fr) * 2007-01-03 2008-07-17 Xgenetics Inc. Procédé de détection précoce d'un cancer
US8288520B2 (en) * 2008-10-27 2012-10-16 Qiagen Gaithersburg, Inc. Fast results hybrid capture assay and system
ES2644516T3 (es) * 2009-01-28 2017-11-29 Qiagen Gaithersburg, Inc. Método y ensayo de preparación de muestras de gran volumen específico de secuencia
US9797000B2 (en) * 2009-05-01 2017-10-24 Qiagen Gaithersburg Inc. Non-target amplification method for detection of RNA splice-forms in a sample
EP2478087B1 (fr) 2009-09-14 2017-01-18 QIAGEN Gaithersburg, Inc. Compositions et méthodes pour la récupération d'acides nucléiques ou de protéines à partir d'échantillons de tissus fixés dans des milieux de cytologie
JP2013517803A (ja) 2010-01-29 2013-05-20 キアジェン ゲイサーズバーグ インコーポレイテッド サンプル中のhpvの存在を決定および確認する方法
CN102822189B (zh) 2010-01-29 2016-06-29 奇亚根盖瑟斯堡股份有限公司 用于核酸的序列特异性纯化和多重复合体分析(multiplex analysis)的方法和组合物
JP2013528049A (ja) 2010-05-19 2013-07-08 キアゲン ガイサーズバーグ アイエヌシー. 核酸の配列特異的な精製及び多重分析のための方法及び組成物
AU2011258501B2 (en) 2010-05-25 2016-07-07 Qiagen Gaithersburg, Inc. Fast results hybrid capture assay and associated strategically-truncated probes
US9885092B2 (en) 2011-02-24 2018-02-06 Qiagen Gaithersburg Inc. Materials and methods for detection of HPV nucleic acids

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4366246A (en) * 1977-11-08 1982-12-28 Genentech, Inc. Method for microbial polypeptide expression
US4293652A (en) * 1979-05-25 1981-10-06 Cetus Corporation Method for synthesizing DNA sequentially
FI63596C (fi) * 1981-10-16 1983-07-11 Orion Yhtymae Oy Mikrobdiagnostiskt foerfarande som grundar sig pao skiktshybridisering av nukleinsyror och vid foerfarandet anvaenda kombinationer av reagenser
GB8306426D0 (en) * 1983-03-09 1983-04-13 Malcolm A D B Detecting polynucleotide sequence
CA1260372A (fr) * 1984-04-27 1989-09-26 Elazar Rabbani Methode d'hybridation pour la detection de materiaux genetiques
US4563417A (en) * 1984-08-31 1986-01-07 Miles Laboratories, Inc. Nucleic acid hybridization assay employing antibodies to intercalation complexes

Also Published As

Publication number Publication date
DK58985D0 (da) 1985-02-08
NO166543B (no) 1991-04-29
RO92633B (ro) 1987-10-31
JPH0463679B2 (fr) 1992-10-12
FI71768C (fi) 1987-02-09
BE901671A (fr) 1985-05-29
DE3505287C2 (de) 1994-01-20
FI840655A (fi) 1985-08-18
SE8500733L (sv) 1985-08-18
GB2156074A (en) 1985-10-02
GB8503900D0 (en) 1985-03-20
US4731325A (en) 1988-03-15
ZA85511B (en) 1985-11-27
HUT37459A (en) 1985-12-28
HU194938B (en) 1988-03-28
SE8500733D0 (sv) 1985-02-15
NL193663B (nl) 2000-02-01
FR2559783B1 (fr) 1990-03-02
AU3842285A (en) 1985-08-22
SE463103B (sv) 1990-10-08
NO850554L (no) 1985-08-19
FI71768B (fi) 1986-10-31
NL8500424A (nl) 1985-09-16
JPS60188100A (ja) 1985-09-25
IT8519432A0 (it) 1985-02-07
IE850202L (en) 1985-08-17
AT394578B (de) 1992-05-11
IT1183184B (it) 1987-10-05
LU85768A1 (fr) 1985-07-24
DE3505287A1 (de) 1985-09-05
DK174675B1 (da) 2003-08-25
DK58985A (da) 1985-08-18
FR2559783A1 (fr) 1985-08-23
CH671778A5 (fr) 1989-09-29
SU1523053A3 (ru) 1989-11-15
FI840655A0 (fi) 1984-02-17
RO92633A (fr) 1987-10-30
IE57652B1 (en) 1993-02-10
ATA44185A (de) 1991-10-15
AU577568B2 (en) 1988-09-29
GB2156074B (en) 1988-03-16
CA1248895A (fr) 1989-01-17
NO166543C (no) 1991-08-07

Similar Documents

Publication Publication Date Title
NL193663C (nl) Werkwijze en kit voor het detecteren van een specifiek nucleïnezuur in een monster.
JP2820749B2 (ja) 核酸ハイブリダイゼーションの増進手段および方法
Meier et al. Antigenic variation is associated with DNA rearrangements in a relapsing fever Borrelia
Tornatore et al. Detection of JC virus DNA in peripheral lymphocytes from patients with and without progressive multifocal leukoencephalopathy
US7960357B2 (en) PKR activation via hybridization chain reaction
Swanson et al. Pilus-gonococcal variants. Evidence for multiple forms of piliation control.
Aldovini et al. Synthesis of the complete trans-activation gene product of human T-lymphotropic virus type III in Escherichia coli: demonstration of immunogenicity in vivo and expression in vitro.
JPS62229068A (ja) サンプル中の核酸配列の存在を検出するための液体ハイブリダイゼ−シヨン法及びそのためのキツト
JP3436538B2 (ja) 改良型の鎖置換アッセイおよびそれに有用な複合体
JPH09501562A (ja) ヒト・免疫不全ウイルスに対する活性を有するオリゴヌクレオチド
US5389515A (en) Isolated nucleotide sequences for identifying Neisseria gonorrhoeae
US6818402B2 (en) Method and kit for the detection of schistosomiasis through the polymerase chain reaction
JPS62502686A (ja) 標的ヌクレオチド配列の検定に有用な試薬複合体を作製するための方法および核酸構築物
US5776693A (en) Specific detection of the mycobacterium tuberculosis
JP4964230B2 (ja) ネコ・ヘモプラズマの分離株
WO1991008310A1 (fr) Detection d'adenovirus humain
RU2135583C1 (ru) ПЛАЗМИДА ДЛЯ ЭКСПРЕССИИ АНТИ-мРНК РЕТРОВИРУСА HIV-1 (ВАРИАНТЫ)
JPH04506747A (ja) リサウィルス感染症の検出法および/または同定法、モコラリサウィルスのペプチドおよび/またはペプチドの断片をコードする遺伝子のクローン化と発現、モコラウィルスおよび/またはリサウィルス群に対するワクチン、および遺伝子工学による前記ワクチンの製造方法
Mahloogi An investigation into the effects of adenosine tracts on nucleosome structure
JPS61158792A (ja) ブル−タングウイルス検出用dnaプロ−ブ

Legal Events

Date Code Title Description
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
CNR Transfer of rights (patent application after its laying open for public inspection)

Free format text: SANGTEC MEDICAL AB

SNR Assignments of patents or rights arising from examined patent applications

Owner name: SANGTEC MOLECULAR DIAGNOSTICS AB

V4 Discontinued because of reaching the maximum lifetime of a patent

Effective date: 20050214