FI840655A - Foerbaettrade nykleinsyrareagenser, foerfarande foer deras framstaellning och anvaendning av dessa. - Google Patents

Foerbaettrade nykleinsyrareagenser, foerfarande foer deras framstaellning och anvaendning av dessa. Download PDF

Info

Publication number
FI840655A
FI840655A FI840655A FI840655A FI840655A FI 840655 A FI840655 A FI 840655A FI 840655 A FI840655 A FI 840655A FI 840655 A FI840655 A FI 840655A FI 840655 A FI840655 A FI 840655A
Authority
FI
Finland
Prior art keywords
nykleinsyrareagenser
foerbaettrade
dessa
foerfarande foer
deras framstaellning
Prior art date
Application number
FI840655A
Other languages
English (en)
Other versions
FI71768B (fi
FI71768C (fi
FI840655A0 (fi
Inventor
Airi Marjatta Palva
Hans Erik Soederlund
Tuula Marjut Ranki
Original Assignee
Orion Yhtymae Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Yhtymae Oy filed Critical Orion Yhtymae Oy
Publication of FI840655A0 publication Critical patent/FI840655A0/fi
Priority to FI840655A priority Critical patent/FI71768C/fi
Priority to ZA85511A priority patent/ZA85511B/xx
Priority to US06/694,325 priority patent/US4731325A/en
Priority to IE202/85A priority patent/IE57652B1/en
Priority to AU38422/85A priority patent/AU577568B2/en
Priority to IT19432/85A priority patent/IT1183184B/it
Priority to BE214463A priority patent/BE901671A/fr
Priority to DK198500589A priority patent/DK174675B1/da
Priority to CA000474112A priority patent/CA1248895A/en
Priority to LU85768A priority patent/LU85768A1/fr
Priority to NO850554A priority patent/NO166543C/no
Priority to NL8500424A priority patent/NL193663C/nl
Priority to AT0044185A priority patent/AT394578B/de
Priority to SE8500733A priority patent/SE463103B/sv
Priority to HU85570A priority patent/HU194938B/hu
Priority to CH725/85A priority patent/CH671778A5/de
Priority to DE3505287A priority patent/DE3505287C2/de
Priority to JP60029207A priority patent/JPS60188100A/ja
Priority to GB08503900A priority patent/GB2156074B/en
Priority to FR858502188A priority patent/FR2559783B1/fr
Priority to SU853856877A priority patent/SU1523053A3/ru
Priority to RO117684A priority patent/RO92633B/ro
Publication of FI840655A publication Critical patent/FI840655A/fi
Publication of FI71768B publication Critical patent/FI71768B/fi
Application granted granted Critical
Publication of FI71768C publication Critical patent/FI71768C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/705—Specific hybridization probes for herpetoviridae, e.g. herpes simplex, varicella zoster
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/682—Signal amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
FI840655A 1984-02-17 1984-02-17 Foerbaettrade nykleinsyrareagenser och foerfarande foer deras framstaellning. FI71768C (fi)

Priority Applications (22)

Application Number Priority Date Filing Date Title
FI840655A FI71768C (fi) 1984-02-17 1984-02-17 Foerbaettrade nykleinsyrareagenser och foerfarande foer deras framstaellning.
ZA85511A ZA85511B (en) 1984-02-17 1985-01-22 Nucleic acid reagents,a method for their preparation and their use
US06/694,325 US4731325A (en) 1984-02-17 1985-01-24 Arrays of alternating nucleic acid fragments for hybridization arrays
IE202/85A IE57652B1 (en) 1984-02-17 1985-01-29 Improved nucleic acid reagents and methods for their preparation
AU38422/85A AU577568B2 (en) 1984-02-17 1985-02-04 Preparation of nucleic acid reagents having arrays of alternating nucleic acid fragments
IT19432/85A IT1183184B (it) 1984-02-17 1985-02-07 Reagenti acidi nucleici perfezionati e procedimenti per laloro preparazione
BE214463A BE901671A (fr) 1984-02-17 1985-02-07 Reactifs d'acide nucleique perfectionnes et procedes pour leur preparation.
DK198500589A DK174675B1 (da) 1984-02-17 1985-02-08 Nukleinsyrereagenser og fremgangsmåde til fremstilling deraf
CA000474112A CA1248895A (en) 1984-02-17 1985-02-12 Nucleic acid reagents, a method for their preparation and their use
LU85768A LU85768A1 (fr) 1984-02-17 1985-02-12 Reactifs d'acide nucleique perfectionnes et procedes pour leur preparation
NO850554A NO166543C (no) 1984-02-17 1985-02-13 Nukleinsyrereagenser og fremgangsmaate til deres fremstilling.
NL8500424A NL193663C (nl) 1984-02-17 1985-02-14 Werkwijze en kit voor het detecteren van een specifiek nucleïnezuur in een monster.
AT0044185A AT394578B (de) 1984-02-17 1985-02-15 Verfahren zur herstellung von nucleinsaeure-reagenzien
FR858502188A FR2559783B1 (fr) 1984-02-17 1985-02-15 Reactifs d'acide nucleique perfectionnes et procedes pour leur preparation
HU85570A HU194938B (en) 1984-02-17 1985-02-15 Process for preparing improved nucleinic acid reagents
CH725/85A CH671778A5 (fi) 1984-02-17 1985-02-15
DE3505287A DE3505287C2 (de) 1984-02-17 1985-02-15 Verbesserte Nucleinsäure-Reagenzien und Verfahren zu ihrer Herstellung
JP60029207A JPS60188100A (ja) 1984-02-17 1985-02-15 核酸試薬
GB08503900A GB2156074B (en) 1984-02-17 1985-02-15 Improved nucleic acid reagents and methods for their preparation
SE8500733A SE463103B (sv) 1984-02-17 1985-02-15 Nukleinsyrareagens bestaaende av minst tvaa serier av minst tvaa uppsaettningar nukleinsyrafragment vilka inte aer homologa till varandra samt saett foer dessas framstaellning
SU853856877A SU1523053A3 (ru) 1984-02-17 1985-02-15 Способ идентификации вирусов и бактерий, основанный на сэндвич-гибридизации нуклеиновых кислот
RO117684A RO92633B (ro) 1984-02-17 1985-02-18 Metoda de preparare a unui reactiv pentru identificarea acizilor nucleici

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI840655A FI71768C (fi) 1984-02-17 1984-02-17 Foerbaettrade nykleinsyrareagenser och foerfarande foer deras framstaellning.
FI840655 1984-02-17

Publications (4)

Publication Number Publication Date
FI840655A0 FI840655A0 (fi) 1984-02-17
FI840655A true FI840655A (fi) 1985-08-18
FI71768B FI71768B (fi) 1986-10-31
FI71768C FI71768C (fi) 1987-02-09

Family

ID=8518568

Family Applications (1)

Application Number Title Priority Date Filing Date
FI840655A FI71768C (fi) 1984-02-17 1984-02-17 Foerbaettrade nykleinsyrareagenser och foerfarande foer deras framstaellning.

Country Status (22)

Country Link
US (1) US4731325A (fi)
JP (1) JPS60188100A (fi)
AT (1) AT394578B (fi)
AU (1) AU577568B2 (fi)
BE (1) BE901671A (fi)
CA (1) CA1248895A (fi)
CH (1) CH671778A5 (fi)
DE (1) DE3505287C2 (fi)
DK (1) DK174675B1 (fi)
FI (1) FI71768C (fi)
FR (1) FR2559783B1 (fi)
GB (1) GB2156074B (fi)
HU (1) HU194938B (fi)
IE (1) IE57652B1 (fi)
IT (1) IT1183184B (fi)
LU (1) LU85768A1 (fi)
NL (1) NL193663C (fi)
NO (1) NO166543C (fi)
RO (1) RO92633B (fi)
SE (1) SE463103B (fi)
SU (1) SU1523053A3 (fi)
ZA (1) ZA85511B (fi)

Families Citing this family (151)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1260372A (en) * 1984-04-27 1989-09-26 Elazar Rabbani Hybridization method for the detection of genetic materials
US4725536A (en) * 1985-09-19 1988-02-16 Genetics Institute, Inc. Reagent polynucleotide complex with multiple target binding regions, and kit and methods
US4876187A (en) * 1985-12-05 1989-10-24 Meiogenics, Inc. Nucleic acid compositions with scissile linkage useful for detecting nucleic acid sequences
US4868105A (en) * 1985-12-11 1989-09-19 Chiron Corporation Solution phase nucleic acid sandwich assay
US4910300A (en) * 1985-12-11 1990-03-20 Chiron Corporation Method for making nucleic acid probes
US4882269A (en) * 1985-12-13 1989-11-21 Princeton University Amplified hybridization assay
FI76119C (fi) * 1986-02-27 1988-09-09 Orion Yhtymae Oy Kvantitativ bestaemning av nukleinsyramolekyler och reagensfoerpackning som anvaends vid foerfarandet.
US4925785A (en) * 1986-03-07 1990-05-15 Biotechnica Diagnostics, Inc. Nucleic acid hybridization assays
EP0577144A1 (en) * 1986-05-01 1994-01-05 Washington Research Foundation Detection of a unique Chlamydia strain associated with acute respiratory disease
US5281518A (en) * 1986-05-01 1994-01-25 Washington Research Foundation Detection of a unique chlamydia strain associated with acute respiratory disease
US6270961B1 (en) * 1987-04-01 2001-08-07 Hyseq, Inc. Methods and apparatus for DNA sequencing and DNA identification
US5202231A (en) * 1987-04-01 1993-04-13 Drmanac Radoje T Method of sequencing of genomes by hybridization of oligonucleotide probes
CA1339351C (en) * 1987-10-15 1997-08-26 Michael S. Urdea Nucleic acid multimers and amplified nucleic acid hybridization assays using same
US5359100A (en) * 1987-10-15 1994-10-25 Chiron Corporation Bifunctional blocked phosphoramidites useful in making nucleic acid mutimers
US5124246A (en) * 1987-10-15 1992-06-23 Chiron Corporation Nucleic acid multimers and amplified nucleic acid hybridization assays using same
CA1323293C (en) * 1987-12-11 1993-10-19 Keith C. Backman Assay using template-dependent nucleic acid probe reorganization
GB8810400D0 (en) * 1988-05-03 1988-06-08 Southern E Analysing polynucleotide sequences
US6054270A (en) * 1988-05-03 2000-04-25 Oxford Gene Technology Limited Analying polynucleotide sequences
US7811751B2 (en) * 1988-05-03 2010-10-12 Oxford Gene Technology Limited Analysing polynucleotide sequences
US5700637A (en) * 1988-05-03 1997-12-23 Isis Innovation Limited Apparatus and method for analyzing polynucleotide sequences and method of generating oligonucleotide arrays
WO1989012696A1 (en) * 1988-06-24 1989-12-28 Amgen Inc. Method and reagents for detecting nucleic acid sequences
US5185243A (en) * 1988-08-25 1993-02-09 Syntex (U.S.A.) Inc. Method for detection of specific nucleic acid sequences
CA2026573A1 (en) * 1989-02-03 1990-08-04 John B. Findlay Nucleic acid test article and its use to detect a predetermined nucleic acid
US6406844B1 (en) 1989-06-07 2002-06-18 Affymetrix, Inc. Very large scale immobilized polymer synthesis
US5925525A (en) * 1989-06-07 1999-07-20 Affymetrix, Inc. Method of identifying nucleotide differences
US5800992A (en) 1989-06-07 1998-09-01 Fodor; Stephen P.A. Method of detecting nucleic acids
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US6379895B1 (en) 1989-06-07 2002-04-30 Affymetrix, Inc. Photolithographic and other means for manufacturing arrays
US6040138A (en) * 1995-09-15 2000-03-21 Affymetrix, Inc. Expression monitoring by hybridization to high density oligonucleotide arrays
US5744101A (en) 1989-06-07 1998-04-28 Affymax Technologies N.V. Photolabile nucleoside protecting groups
US6551784B2 (en) 1989-06-07 2003-04-22 Affymetrix Inc Method of comparing nucleic acid sequences
US6309822B1 (en) 1989-06-07 2001-10-30 Affymetrix, Inc. Method for comparing copy number of nucleic acid sequences
US6346413B1 (en) 1989-06-07 2002-02-12 Affymetrix, Inc. Polymer arrays
US5424186A (en) 1989-06-07 1995-06-13 Affymax Technologies N.V. Very large scale immobilized polymer synthesis
US6955915B2 (en) * 1989-06-07 2005-10-18 Affymetrix, Inc. Apparatus comprising polymers
US6919211B1 (en) * 1989-06-07 2005-07-19 Affymetrix, Inc. Polypeptide arrays
US5232829A (en) * 1989-09-29 1993-08-03 Hoffmann-La Roche Inc. Detection of chlamydia trachomatis by polymerase chain reaction using biotin labelled lina primers and capture probes
US6506558B1 (en) 1990-03-07 2003-01-14 Affymetrix Inc. Very large scale immobilized polymer synthesis
CA2039517C (en) * 1990-04-03 2006-11-07 David Segev Dna probe signal amplification
US5071962A (en) * 1990-05-31 1991-12-10 The United State Of America As Represented By The Department Of Health And Human Services Nucleotide, deduced amino acid sequence, isolation and purification of heat-shock chlamydial proteins
DE69112309T2 (de) * 1990-06-28 1996-01-25 Wakunaga Seiyaku Kk Verfahren zum Nukleinsäurenachweis.
US5645994A (en) * 1990-07-05 1997-07-08 University Of Utah Research Foundation Method and compositions for identification of species in a sample using type II topoisomerase sequences
GB9020621D0 (en) * 1990-09-21 1990-10-31 Imp Cancer Res Tech Identification of organisms
GB2262987A (en) * 1990-09-21 1993-07-07 Imp Cancer Res Tech Identification of organisms
EP0562047A4 (en) * 1990-12-06 1995-11-02 Affymax Tech Nv Sequencing by hybridization of a target nucleic acid to a matrix of defined oligonucleotides
US5437976A (en) * 1991-08-08 1995-08-01 Arizona Board Of Regents, The University Of Arizona Multi-domain DNA ligands bound to a solid matrix for protein and nucleic acid affinity chromatography and processing of solid-phase DNA
US6051380A (en) 1993-11-01 2000-04-18 Nanogen, Inc. Methods and procedures for molecular biological analysis and diagnostics
US6569382B1 (en) * 1991-11-07 2003-05-27 Nanogen, Inc. Methods apparatus for the electronic, homogeneous assembly and fabrication of devices
US5605662A (en) * 1993-11-01 1997-02-25 Nanogen, Inc. Active programmable electronic devices for molecular biological analysis and diagnostics
US6017696A (en) * 1993-11-01 2000-01-25 Nanogen, Inc. Methods for electronic stringency control for molecular biological analysis and diagnostics
US5849486A (en) * 1993-11-01 1998-12-15 Nanogen, Inc. Methods for hybridization analysis utilizing electrically controlled hybridization
US5632957A (en) 1993-11-01 1997-05-27 Nanogen Molecular biological diagnostic systems including electrodes
US6652808B1 (en) * 1991-11-07 2003-11-25 Nanotronics, Inc. Methods for the electronic assembly and fabrication of devices
US6048690A (en) * 1991-11-07 2000-04-11 Nanogen, Inc. Methods for electronic fluorescent perturbation for analysis and electronic perturbation catalysis for synthesis
US5556961A (en) * 1991-11-15 1996-09-17 Foote; Robert S. Nucleosides with 5'-O-photolabile protecting groups
EP0624059A4 (en) 1991-11-22 1994-12-21 Affymax Technologies N.V. Combinatorial strategies for polymer synthesis.
US6849462B1 (en) 1991-11-22 2005-02-01 Affymetrix, Inc. Combinatorial strategies for polymer synthesis
US6468740B1 (en) 1992-11-05 2002-10-22 Affymetrix, Inc. Cyclic and substituted immobilized molecular synthesis
US6943034B1 (en) 1991-11-22 2005-09-13 Affymetrix, Inc. Combinatorial strategies for polymer synthesis
WO1993013221A1 (en) * 1991-12-23 1993-07-08 Chiron Corporation Chlamydiae probes for use in solution phase sandwich hybridization assays
EP0625214A4 (en) * 1991-12-23 1997-07-16 Chiron Corp Cmv probes for use in solution phase sandwich hybridization assays.
US5583211A (en) * 1992-10-29 1996-12-10 Beckman Instruments, Inc. Surface activated organic polymers useful for location - specific attachment of nucleic acids, peptides, proteins and oligosaccharides
US7713528B1 (en) 1993-02-18 2010-05-11 Enzo Therapeutics, Inc. Method for in vivo delivery of active compounds using reagent conjugate
AU7551094A (en) * 1993-07-23 1995-02-20 Hyseq, Inc. Method for screening unknown organisms
FR2710075B1 (fr) * 1993-09-15 1995-10-27 Bio Merieux Réactif et procédé pour la détection d'une séquence nucléotidique avec amplification de signal.
US6315953B1 (en) 1993-11-01 2001-11-13 Nanogen, Inc. Devices for molecular biological analysis and diagnostics including waveguides
US6375899B1 (en) 1993-11-01 2002-04-23 Nanogen, Inc. Electrophoretic buss for transport of charged materials in a multi-chamber system
US6726880B1 (en) 1993-11-01 2004-04-27 Nanogen, Inc. Electronic device for performing active biological operations and method of using same
US6319472B1 (en) 1993-11-01 2001-11-20 Nanogen, Inc. System including functionally separated regions in electrophoretic system
US6068818A (en) 1993-11-01 2000-05-30 Nanogen, Inc. Multicomponent devices for molecular biological analysis and diagnostics
US6638482B1 (en) 1993-11-01 2003-10-28 Nanogen, Inc. Reconfigurable detection and analysis apparatus and method
US20040077074A1 (en) * 1993-11-01 2004-04-22 Nanogen, Inc. Multi-chambered analysis device
US7172864B1 (en) 1993-11-01 2007-02-06 Nanogen Methods for electronically-controlled enzymatic reactions
US7314708B1 (en) * 1998-08-04 2008-01-01 Nanogen, Inc. Method and apparatus for electronic synthesis of molecular structures
US6309602B1 (en) 1993-11-01 2001-10-30 Nanogen, Inc. Stacked, reconfigurable system for electrophoretic transport of charged materials
US6287517B1 (en) 1993-11-01 2001-09-11 Nanogen, Inc. Laminated assembly for active bioelectronic devices
US6254827B1 (en) 1993-11-01 2001-07-03 Nanogen, Inc. Methods for fabricating multi-component devices for molecular biological analysis and diagnostics
US7101661B1 (en) 1993-11-01 2006-09-05 Nanogen, Inc. Apparatus for active programmable matrix devices
US7582421B2 (en) * 1993-11-01 2009-09-01 Nanogen, Inc. Methods for determination of single nucleic acid polymorphisms using a bioelectronic microchip
US6225059B1 (en) 1993-11-01 2001-05-01 Nanogen, Inc. Advanced active electronic devices including collection electrodes for molecular biological analysis and diagnostics
US6331274B1 (en) 1993-11-01 2001-12-18 Nanogen, Inc. Advanced active circuits and devices for molecular biological analysis and diagnostics
US6287850B1 (en) * 1995-06-07 2001-09-11 Affymetrix, Inc. Bioarray chip reaction apparatus and its manufacture
EP0695941B1 (en) * 1994-06-08 2002-07-31 Affymetrix, Inc. Method and apparatus for packaging a chip
US5807522A (en) * 1994-06-17 1998-09-15 The Board Of Trustees Of The Leland Stanford Junior University Methods for fabricating microarrays of biological samples
US7323298B1 (en) * 1994-06-17 2008-01-29 The Board Of Trustees Of The Leland Stanford Junior University Microarray for determining the relative abundances of polynuceotide sequences
US7378236B1 (en) 1994-06-17 2008-05-27 The Board Of Trustees Of The Leland Stanford Junior University Method for analyzing gene expression patterns
US6306657B1 (en) * 1994-06-28 2001-10-23 Kalyx Biosciences, Inc. Polynucleotide probe and kit for amplifying signal detection in hybridization assays
US6403367B1 (en) 1994-07-07 2002-06-11 Nanogen, Inc. Integrated portable biological detection system
US7857957B2 (en) * 1994-07-07 2010-12-28 Gamida For Life B.V. Integrated portable biological detection system
US6121048A (en) * 1994-10-18 2000-09-19 Zaffaroni; Alejandro C. Method of conducting a plurality of reactions
US8236493B2 (en) * 1994-10-21 2012-08-07 Affymetrix, Inc. Methods of enzymatic discrimination enhancement and surface-bound double-stranded DNA
US6720149B1 (en) * 1995-06-07 2004-04-13 Affymetrix, Inc. Methods for concurrently processing multiple biological chip assays
US20040086917A1 (en) * 1995-09-27 2004-05-06 Nanogen, Inc. Methods for electronic fluorescent perturbation for analysis and electronic perturbation catalysis for synthesis
EP0880598A4 (en) * 1996-01-23 2005-02-23 Affymetrix Inc RAPID EVALUATION OF NUCLEIC ACID ABUNDANCE DIFFERENCE, WITH A HIGH-DENSITY OLIGONUCLEOTIDE SYSTEM
US6706473B1 (en) 1996-12-06 2004-03-16 Nanogen, Inc. Systems and devices for photoelectrophoretic transport and hybridization of oligonucleotides
US20020042048A1 (en) 1997-01-16 2002-04-11 Radoje Drmanac Methods and compositions for detection or quantification of nucleic acid species
US6297006B1 (en) 1997-01-16 2001-10-02 Hyseq, Inc. Methods for sequencing repetitive sequences and for determining the order of sequence subfragments
US6309824B1 (en) 1997-01-16 2001-10-30 Hyseq, Inc. Methods for analyzing a target nucleic acid using immobilized heterogeneous mixtures of oligonucleotide probes
US6326489B1 (en) 1997-08-05 2001-12-04 Howard Hughes Medical Institute Surface-bound, bimolecular, double-stranded DNA arrays
DE19741715A1 (de) 1997-09-22 1999-03-25 Hoechst Ag Pentopyranosyl-Nucleosid, seine Herstellung und Verwendung
AU737174B2 (en) 1997-10-10 2001-08-09 President & Fellows Of Harvard College Replica amplification of nucleic acid arrays
US6548021B1 (en) 1997-10-10 2003-04-15 President And Fellows Of Harvard College Surface-bound, double-stranded DNA protein arrays
US6511803B1 (en) 1997-10-10 2003-01-28 President And Fellows Of Harvard College Replica amplification of nucleic acid arrays
US6485944B1 (en) 1997-10-10 2002-11-26 President And Fellows Of Harvard College Replica amplification of nucleic acid arrays
CA2313483C (en) * 1997-12-12 2017-12-05 Digene Corporation Assessment of human papilloma virus-related disease
US6355419B1 (en) 1998-04-27 2002-03-12 Hyseq, Inc. Preparation of pools of nucleic acids based on representation in a sample
US6232067B1 (en) 1998-08-17 2001-05-15 The Perkin-Elmer Corporation Adapter directed expression analysis
US6545264B1 (en) 1998-10-30 2003-04-08 Affymetrix, Inc. Systems and methods for high performance scanning
US7612020B2 (en) * 1998-12-28 2009-11-03 Illumina, Inc. Composite arrays utilizing microspheres with a hybridization chamber
AU4025300A (en) * 1999-03-24 2000-10-09 Packard Bioscience Company Continuous porous matrix arrays
WO2000058522A1 (en) * 1999-03-30 2000-10-05 Nanogen, Inc. Single nucleotide polymorphic discrimination by electronic dot blot assay on semiconductor microchips
US6897072B1 (en) 1999-04-27 2005-05-24 Ciphergen Biosystems, Inc. Probes for a gas phase ion spectrometer
EP1054259A1 (en) * 1999-05-19 2000-11-22 Remacle, José Method for the identification of a target compound
US20030096321A1 (en) * 1999-05-19 2003-05-22 Jose Remacle Method for the identification and/or the quantification of a target compound obtained from a biological sample upon chips
US6465183B2 (en) * 1999-07-01 2002-10-15 Agilent Technologies, Inc. Multidentate arrays
JP2001017166A (ja) * 1999-07-02 2001-01-23 Fuji Photo Film Co Ltd Ｄｎａチップ、ｄｎａチップの検定キットおよびｄｎａチップの検定法
US6428957B1 (en) 1999-11-08 2002-08-06 Agilent Technologies, Inc. Systems tools and methods of assaying biological materials using spatially-addressable arrays
US6235483B1 (en) 2000-01-31 2001-05-22 Agilent Technologies, Inc. Methods and kits for indirect labeling of nucleic acids
US8076063B2 (en) 2000-02-07 2011-12-13 Illumina, Inc. Multiplexed methylation detection methods
US7955794B2 (en) 2000-09-21 2011-06-07 Illumina, Inc. Multiplex nucleic acid reactions
US7582420B2 (en) 2001-07-12 2009-09-01 Illumina, Inc. Multiplex nucleic acid reactions
US6455007B1 (en) * 2000-06-13 2002-09-24 Symyx Technologies, Inc. Apparatus and method for testing compositions in contact with a porous medium
US7439016B1 (en) 2000-06-15 2008-10-21 Digene Corporation Detection of nucleic acids by type-specific hybrid capture method
US7601497B2 (en) 2000-06-15 2009-10-13 Qiagen Gaithersburg, Inc. Detection of nucleic acids by target-specific hybrid capture method
US6905816B2 (en) 2000-11-27 2005-06-14 Intelligent Medical Devices, Inc. Clinically intelligent diagnostic devices and methods
DK1373573T3 (da) * 2001-03-09 2014-01-20 Trovagene Inc Konjugatsonder og optisk detektion af analytter
WO2003006677A2 (en) 2001-07-12 2003-01-23 Illumina, Inc. Multiplex nucleic acid reactions
US6893822B2 (en) 2001-07-19 2005-05-17 Nanogen Recognomics Gmbh Enzymatic modification of a nucleic acid-synthetic binding unit conjugate
US7601493B2 (en) * 2002-07-26 2009-10-13 Nanogen, Inc. Methods and apparatus for screening and detecting multiple genetic mutations
US20040241659A1 (en) * 2003-05-30 2004-12-02 Applera Corporation Apparatus and method for hybridization and SPR detection
US7622281B2 (en) 2004-05-20 2009-11-24 The Board Of Trustees Of The Leland Stanford Junior University Methods and compositions for clonal amplification of nucleic acid
US7828954B2 (en) * 2004-09-21 2010-11-09 Gamida For Life B.V. Electrode based patterning of thin film self-assembled nanoparticles
US7314542B2 (en) * 2004-09-23 2008-01-01 Nanogen, Inc. Methods and materials for optimization of electronic transportation and hybridization reactions
US20060246576A1 (en) * 2005-04-06 2006-11-02 Affymetrix, Inc. Fluidic system and method for processing biological microarrays in personal instrumentation
EP1877581B1 (en) 2005-05-06 2012-03-28 Gen-Probe Incorporated Methods and products for nucleic acid target capture
WO2007070553A2 (en) * 2005-12-12 2007-06-21 The Johns Hopkins University Double-tiled and multi-tiled arrays and methods thereof
WO2008060369A2 (en) 2006-09-29 2008-05-22 Translational Therapeutics, Inc. Eif4e regulon-based diagnostics
JP2009522281A (ja) 2005-12-28 2009-06-11 トランスレーショナル セラピューティクス，インク． 翻訳機能障害に基づく治療法
US20080003667A1 (en) * 2006-05-19 2008-01-03 Affymetrix, Inc. Consumable elements for use with fluid processing and detection systems
EP1912067A1 (en) * 2006-10-12 2008-04-16 Eppendorf Array Technologies S.A. Method for quantification of a target compound obtained from a biological sample upon chips
US9938641B2 (en) * 2006-12-18 2018-04-10 Fluidigm Corporation Selection of aptamers based on geometry
WO2008085777A2 (en) * 2007-01-03 2008-07-17 Xgenetics Inc. A method for early detection of cancer
CA2741650C (en) 2008-10-27 2017-09-05 Qiagen Gaithersburg Inc. Fast results hybrid capture assay and system
US20100216147A1 (en) * 2009-01-28 2010-08-26 Qiagen Gaithersburg, Inc. Sequence-specific large volume sample preparation method and assay
US9797000B2 (en) * 2009-05-01 2017-10-24 Qiagen Gaithersburg Inc. Non-target amplification method for detection of RNA splice-forms in a sample
US9410146B2 (en) 2009-09-14 2016-08-09 Qiagen Gaithersburg Inc. Compositions and methods for recovery of nucleic acids or proteins from tissue samples fixed in cytology media
US9605303B2 (en) 2010-01-29 2017-03-28 Qiagen Gaithersburg, Inc. Method of determining and confirming the presence of an HPV in a sample
CA2787924A1 (en) 2010-01-29 2011-08-04 Qiagen Gaithersburg, Inc. Methods and compositions for sequence-specific purification and multiplex analysis of nucleic acids
US9422593B2 (en) 2010-05-19 2016-08-23 Qiagen Gaithresburg, Inc Methods and compositions for sequence-specific purification and multiplex analysis of nucleic acids
JP6153866B2 (ja) 2010-05-25 2017-06-28 キアゲン ガイサーズバーグ アイエヌシー． 迅速なハイブリッド捕捉アッセイ、及び関連する戦略的に切断されたプローブ
US9885092B2 (en) 2011-02-24 2018-02-06 Qiagen Gaithersburg Inc. Materials and methods for detection of HPV nucleic acids

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4366246A (en) * 1977-11-08 1982-12-28 Genentech, Inc. Method for microbial polypeptide expression
US4293652A (en) * 1979-05-25 1981-10-06 Cetus Corporation Method for synthesizing DNA sequentially
FI63596C (fi) * 1981-10-16 1983-07-11 Orion Yhtymae Oy Mikrobdiagnostiskt foerfarande som grundar sig pao skiktshybridisering av nukleinsyror och vid foerfarandet anvaenda kombinationer av reagenser
GB8306426D0 (en) * 1983-03-09 1983-04-13 Malcolm A D B Detecting polynucleotide sequence
CA1260372A (en) * 1984-04-27 1989-09-26 Elazar Rabbani Hybridization method for the detection of genetic materials
US4563417A (en) * 1984-08-31 1986-01-07 Miles Laboratories, Inc. Nucleic acid hybridization assay employing antibodies to intercalation complexes

Also Published As

Publication number Publication date
ATA44185A (de) 1991-10-15
NL8500424A (nl) 1985-09-16
RO92633A (ro) 1987-10-30
FR2559783B1 (fr) 1990-03-02
JPH0463679B2 (fi) 1992-10-12
DE3505287C2 (de) 1994-01-20
IT1183184B (it) 1987-10-05
SU1523053A3 (ru) 1989-11-15
NO166543B (no) 1991-04-29
FI71768B (fi) 1986-10-31
AT394578B (de) 1992-05-11
NL193663C (nl) 2000-06-06
DK58985A (da) 1985-08-18
JPS60188100A (ja) 1985-09-25
SE463103B (sv) 1990-10-08
FI71768C (fi) 1987-02-09
SE8500733D0 (sv) 1985-02-15
NL193663B (nl) 2000-02-01
ZA85511B (en) 1985-11-27
HU194938B (en) 1988-03-28
GB8503900D0 (en) 1985-03-20
GB2156074A (en) 1985-10-02
NO166543C (no) 1991-08-07
DK174675B1 (da) 2003-08-25
AU3842285A (en) 1985-08-22
DE3505287A1 (de) 1985-09-05
LU85768A1 (fr) 1985-07-24
HUT37459A (en) 1985-12-28
IT8519432A0 (it) 1985-02-07
CH671778A5 (fi) 1989-09-29
FR2559783A1 (fr) 1985-08-23
IE57652B1 (en) 1993-02-10
RO92633B (ro) 1987-10-31
NO850554L (no) 1985-08-19
BE901671A (fr) 1985-05-29
IE850202L (en) 1985-08-17
CA1248895A (en) 1989-01-17
AU577568B2 (en) 1988-09-29
FI840655A0 (fi) 1984-02-17
US4731325A (en) 1988-03-15
SE8500733L (sv) 1985-08-18
GB2156074B (en) 1988-03-16
DK58985D0 (da) 1985-02-08

Similar Documents

Publication Publication Date Title
FI840655A (fi) Foerbaettrade nykleinsyrareagenser, foerfarande foer deras framstaellning och anvaendning av dessa.
FI852659A0 (fi) Foerstadier av 3-hydroximorfinaner, substituerade benzoatesterderivat, deras mellanprodukter och foerfaranden.
FI843929L (fi) Skivstruktur i flera skikt, foerfarande foer framstaellning av densamma och behaollare framstaellda daerav.
FI862591A0 (fi) Profilpelare foer fastspaenning av skivor, saerskilt glasskivor, foer utstaellningsvitriner, foersaeljningsbord marknadsloesare och motsvarande.
FI852916A0 (fi) Kinonderivat, deras framstaellning och anvaendning.
FI851824A0 (fi) Lampor foer flygstationers upphoejda startbanor, taxibanor och troeskelkanter.
FI850266L (fi) Azolylarylalkanolderivat, foerfarande foer deras framstaellning och deras anvaendning.
FI852657L (fi) Heterocykliska farmaceutiska foereningar, framstaellning och anvaendning.
FI853224A0 (fi) Foerfarande och anordning foer framstaellning av haolplattor och motsvarande byggelement, foeretraedesvis av betong.
FI853513A0 (fi) Foeroreningsavlaegsningsenhet foer verktyg foer avlaegsnande av radioaktiv, kemisk och biologisk foerorening fraon dessa.
FI852464A0 (fi) Foerfarande foer framstaellning av flerskiktkretskort en medelst detta foerfarande framstaelld, fastsatt skiktstruktur och anvaendning av denna skiktstruktur i detta framstaellningsfoerfarande.
FI863081A (fi) Foerfarande foer aostadkommande av en skyddad omgivning omkring en arbetszon, skyddshoelje foer utfoerande av foerfarandet och foerfarande foer foerpackning av skyddshoeljet.
FI850324L (fi) Benzopyranderivat, dessa innehaollande kompositioner och foerfarande foer deras framstaellning.
FI852105A0 (fi) Acylerade sockerderivat, foerfarande foer deras framstaellning och deras anvaendning.
FI844419A0 (fi) Foerfarande foer styrning av alkalisk cellulosakokning medelst en snabb analysator, vilken maeter oorganiska och organiska kokvaetskekomponenter.
FI850841L (fi) Korsfogsbalkar, fraesmaskin foer framstaellning av dessa och av dessa framstaellda byggnader.
FI850702L (fi) Diazepinindoler, deras framstaellning och dessa innehaollande farmaceutiska foereningar.
FI843895L (fi) Foerfarande foer avlaegsnande av vatten fraon en fiberbana, speciellt fraon en pappers- eller kartongbana och en vaotpress i en pappersmaskin foer tillaempning av foerfarandet.
FI851055A0 (fi) Tetrahydropyrimidin- och imidatzolin- derivator, foerfarande foer deras framstaellning och deras anvaendning.
FI851204A0 (fi) Eburnanderivat, foerfarande foer deras framstaellning och dessa innehaollande farmaceutiska blandningar.
FI844307A0 (fi) Foerankringssockel foer faestande av haengstaellningar, gaongbroar, reklamskyltar och motsvarande.
FI854805A0 (fi) Foerfarande foer framstaellning av skumflotationssamlare, en skumflotationssamlare och skumflotationsfoerfarande.
FI853964A0 (fi) Kopplingsskivuppsaettning, handtelefon och foerfarande foer framstaellning av en kopplingsskivuppsaettning foer en handtelefon.
FI840524A (fi) Koppling foer plastroer, foerfarande foer framstaellning av kopplingen och verktyg foer foerverkligande av foerfarande foerfarandet.
FI843957A0 (fi) Nyckel foer tilldragning och loesande av muttrar, skruvar och liknande.

Legal Events

Date Code Title Description
PC Transfer of assignment of patent

Owner name: SANGTEC MEDICAL AB

MA Patent expired

Owner name: SANGTEC MOLECULAR DIAGNOSTICS AB