NL192739C - £3H|-imidazo-£5,1-d|-1,2,3,5-tetrazine-4-on derivaten en farmaceutische samenstellingen, die deze derivaten bevatten. - Google Patents

£3H|-imidazo-£5,1-d|-1,2,3,5-tetrazine-4-on derivaten en farmaceutische samenstellingen, die deze derivaten bevatten. Download PDF

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Publication number
NL192739C
NL192739C NL8203286A NL8203286A NL192739C NL 192739 C NL192739 C NL 192739C NL 8203286 A NL8203286 A NL 8203286A NL 8203286 A NL8203286 A NL 8203286A NL 192739 C NL192739 C NL 192739C
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NL
Netherlands
Prior art keywords
tetrazine
imidazo
derivatives
chloroethyl
carbamoyl
Prior art date
Application number
NL8203286A
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English (en)
Dutch (nl)
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NL192739B (nl
NL8203286A (nl
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Cancer Res Campaign Tech
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Publication date
Application filed by Cancer Res Campaign Tech filed Critical Cancer Res Campaign Tech
Publication of NL8203286A publication Critical patent/NL8203286A/nl
Publication of NL192739B publication Critical patent/NL192739B/xx
Application granted granted Critical
Publication of NL192739C publication Critical patent/NL192739C/nl

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
NL8203286A 1981-08-24 1982-08-23 £3H|-imidazo-£5,1-d|-1,2,3,5-tetrazine-4-on derivaten en farmaceutische samenstellingen, die deze derivaten bevatten. NL192739C (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8125791 1981-08-24
GB8125791 1981-08-24

Publications (3)

Publication Number Publication Date
NL8203286A NL8203286A (nl) 1983-03-16
NL192739B NL192739B (nl) 1997-09-01
NL192739C true NL192739C (nl) 1998-01-06

Family

ID=10524141

Family Applications (2)

Application Number Title Priority Date Filing Date
NL8203286A NL192739C (nl) 1981-08-24 1982-08-23 £3H|-imidazo-£5,1-d|-1,2,3,5-tetrazine-4-on derivaten en farmaceutische samenstellingen, die deze derivaten bevatten.
NL990010C NL990010I2 (nl) 1981-08-24 1999-04-01 Ä3HÜ-imidazo-Ä5,1-dÜ-1,2,3,5-tetrazine-4-on derivaten en farmaceutische samenstellingen, die deze d erivaten bevatten.

Family Applications After (1)

Application Number Title Priority Date Filing Date
NL990010C NL990010I2 (nl) 1981-08-24 1999-04-01 Ä3HÜ-imidazo-Ä5,1-dÜ-1,2,3,5-tetrazine-4-on derivaten en farmaceutische samenstellingen, die deze d erivaten bevatten.

Country Status (29)

Country Link
JP (1) JPS5843975A (ja)
KR (1) KR890000094B1 (ja)
AT (1) AT380256B (ja)
AU (1) AU571430B2 (ja)
BE (1) BE894175A (ja)
CA (1) CA1197247A (ja)
CH (1) CH655114A5 (ja)
DE (2) DE19975037I2 (ja)
DK (1) DK161147C (ja)
ES (1) ES8400438A1 (ja)
FI (1) FI73434C (ja)
FR (1) FR2511679A1 (ja)
GB (1) GB2104522B (ja)
GE (1) GEP19960641B (ja)
GR (1) GR76863B (ja)
HU (1) HU186107B (ja)
IE (1) IE53408B1 (ja)
IL (1) IL66606A (ja)
IT (1) IT1152505B (ja)
LT (1) LT2436B (ja)
LU (1) LU84347A1 (ja)
LV (2) LV5511A3 (ja)
NL (2) NL192739C (ja)
NZ (1) NZ201668A (ja)
OA (1) OA07174A (ja)
SE (1) SE448543B (ja)
SU (1) SU1447284A3 (ja)
UA (1) UA5971A1 (ja)
ZA (1) ZA826120B (ja)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260291A (en) * 1981-08-24 1993-11-09 Cancer Research Campaign Technology Limited Tetrazine derivatives
GB2125402B (en) * 1982-08-17 1985-11-13 May & Baker Ltd New tetrazine derivatives
GR78688B (ja) * 1982-08-17 1984-09-27 May & Baker Ltd
US4517182A (en) * 1983-05-24 1985-05-14 Warner-Lambert Company 3-(Haloethyl)-4-oxopyrazolo-[5,1-d]-1,2,3,5-tetrazine-8-carboxamide composition
GB8616125D0 (en) * 1986-07-02 1986-08-06 May & Baker Ltd Compositions of matter
AU622330B2 (en) * 1989-06-23 1992-04-02 Takeda Chemical Industries Ltd. Condensed heterocyclic compounds having a nitrogen atom in the bridgehead for use as fungicides
EP2275425A1 (en) * 2003-12-30 2011-01-19 Chemagis Ltd. Novel crystalline forms of temozolomide
WO2006077428A1 (en) 2005-01-21 2006-07-27 Astex Therapeutics Limited Pharmaceutical compounds
AR060635A1 (es) 2006-04-27 2008-07-02 Banyu Pharma Co Ltd Derivados de 1,2-dihidro-3h-pirazolo[3,4-d]pirimidin-3-ona, composiciones farmaceuticas que los comprenden y su uso en el tratamiento del cancer
JP2008081492A (ja) 2006-08-31 2008-04-10 Banyu Pharmaceut Co Ltd オーロラａ選択的阻害作用を有する新規アミノピリジン誘導体
EP2073807A1 (en) 2006-10-12 2009-07-01 Astex Therapeutics Limited Pharmaceutical combinations
WO2008044041A1 (en) 2006-10-12 2008-04-17 Astex Therapeutics Limited Pharmaceutical combinations
WO2009054332A1 (ja) 2007-10-23 2009-04-30 Banyu Pharmaceutical Co., Ltd. ピリドン置換ジヒドロピラゾロピリミジノン誘導体
PE20091101A1 (es) * 2007-12-18 2009-07-26 Pharminox Ltd AMIDAS DE ACIDO 3-SUBSTITUIDO-4-OXO-3,4-DIHIDRO-IMIDAZO[5,1-d] [1,2,3,5-TETRACINA-8-CARBOXILICO Y SU EMPLEO
EP2367828B1 (en) * 2008-11-24 2014-06-11 Reliance Life Sciences Pvt., Ltd. Process for the preparation of tetrazine derivatives
US8481503B2 (en) 2009-03-06 2013-07-09 Merck Sharp & Dohme Corp. Combination cancer therapy with an AKT inhibitor and other anticancer agents
BRPI1011822A2 (pt) 2009-06-23 2016-03-29 Pharminox Ltd "compostos de 3-substituída-8-substituída-3h-imidazo[5,1-d][1,2,3,5-tetrazin-4-ona e sua aplicação"
RU2462466C1 (ru) * 2011-06-24 2012-09-27 Автономная Некоммерческая Организация "Научно-Исследовательский Центр Биотехнологии Антибиотиков И Других Биологически Активных Веществ "Биоан" Замещенные азоло[1,2,4,5]тетразины - ингибиторы актинобактериальных серин-треониновых протеинкиназ
EP2766041B1 (en) 2011-10-12 2018-12-05 Children's Medical Center Corporation Combinatorial compositions and methods of treating hemoglobinopathies
AU2017233898B2 (en) 2016-03-15 2022-12-15 Oryzon Genomics, S.A. Combinations of LSD1 inhibitors for use in the treatment of solid tumors
KR101847342B1 (ko) * 2017-05-08 2018-04-11 (주)센텍코리아 웨어러블 체지방 연소량 측정기

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2932305A1 (de) * 1979-08-09 1981-02-26 Basf Ag Azolo- eckige klammer auf 5,1-d eckige klammer zu - eckige klammer auf 1,2,3,5 eckige klammer zu -tetrazin-4-one und verfahren zur herstellung dieser verbindungen

Also Published As

Publication number Publication date
DE19975037I2 (de) 2001-06-13
LV5511A3 (lv) 1994-03-10
FR2511679B1 (ja) 1985-02-01
FI822921L (fi) 1983-02-25
IE822026L (en) 1983-02-24
LU84347A1 (fr) 1983-06-07
GB2104522B (en) 1985-06-12
AU8749382A (en) 1983-03-03
DK377882A (da) 1983-02-25
KR840001175A (ko) 1984-03-28
NL990010I2 (nl) 1999-09-01
CA1197247A (fr) 1985-11-26
SE448543B (sv) 1987-03-02
NZ201668A (en) 1985-08-16
IE53408B1 (en) 1988-11-09
NL192739B (nl) 1997-09-01
SU1447284A3 (ru) 1988-12-23
FI73434C (fi) 1987-10-09
DE3231255A1 (de) 1983-03-03
ATA319182A (de) 1985-09-15
FR2511679A1 (fr) 1983-02-25
ES515176A0 (es) 1983-11-01
FI73434B (fi) 1987-06-30
GEP19960641B (en) 1996-11-15
GB2104522A (en) 1983-03-09
LV5621A3 (lv) 1994-05-10
SE8204817D0 (sv) 1982-08-23
AT380256B (de) 1986-05-12
GR76863B (ja) 1984-09-04
AU571430B2 (en) 1988-04-21
LT2436B (lt) 1994-02-15
CH655114A5 (fr) 1986-03-27
FI822921A0 (fi) 1982-08-23
IT8222938A0 (it) 1982-08-23
OA07174A (fr) 1984-04-30
JPS5843975A (ja) 1983-03-14
NL990010I1 (nl) 1999-07-01
DE3231255C2 (ja) 1992-02-27
DK161147C (da) 1991-11-18
IT1152505B (it) 1987-01-07
ZA826120B (en) 1983-07-27
HU186107B (en) 1985-06-28
DK161147B (da) 1991-06-03
IL66606A0 (en) 1982-12-31
BE894175A (fr) 1983-02-23
NL8203286A (nl) 1983-03-16
ES8400438A1 (es) 1983-11-01
SE8204817L (sv) 1983-02-25
IL66606A (en) 1987-07-31
JPH045029B2 (ja) 1992-01-30
UA5971A1 (uk) 1994-12-29
KR890000094B1 (ko) 1989-03-07

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