FI822921A0 - Foerfarande foer framstaellning av /3h/-imidazo-/5,1-d/-1,2,3,5-tetrazin-4-onderivat med terapeutisk verkan - Google Patents

Foerfarande foer framstaellning av /3h/-imidazo-/5,1-d/-1,2,3,5-tetrazin-4-onderivat med terapeutisk verkan

Info

Publication number
FI822921A0
FI822921A0 FI822921A FI822921A FI822921A0 FI 822921 A0 FI822921 A0 FI 822921A0 FI 822921 A FI822921 A FI 822921A FI 822921 A FI822921 A FI 822921A FI 822921 A0 FI822921 A0 FI 822921A0
Authority
FI
Finland
Prior art keywords
oner
tetrazine
imidazo
administration
frequency requirement
Prior art date
Application number
FI822921A
Other languages
English (en)
Other versions
FI73434C (fi
FI822921L (fi
FI73434B (fi
Inventor
Edward Lunt
Malcolm Francis Graham Stevens
Robert Stone
Kenneth Robert Harr Wooldringe
Original Assignee
May & Baker Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by May & Baker Ltd filed Critical May & Baker Ltd
Publication of FI822921A0 publication Critical patent/FI822921A0/fi
Publication of FI822921L publication Critical patent/FI822921L/fi
Application granted granted Critical
Publication of FI73434B publication Critical patent/FI73434B/fi
Publication of FI73434C publication Critical patent/FI73434C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
FI822921A 1981-08-24 1982-08-23 Foerfarande foer framstaellning av /3h/-imidazo-/5,1-d/-1,2,3,5-tetrazin-4-onderivat med terapeutisk verkan. FI73434C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8125791 1981-08-24
GB8125791 1981-08-24

Publications (4)

Publication Number Publication Date
FI822921A0 true FI822921A0 (fi) 1982-08-23
FI822921L FI822921L (fi) 1983-02-25
FI73434B FI73434B (fi) 1987-06-30
FI73434C FI73434C (fi) 1987-10-09

Family

ID=10524141

Family Applications (1)

Application Number Title Priority Date Filing Date
FI822921A FI73434C (fi) 1981-08-24 1982-08-23 Foerfarande foer framstaellning av /3h/-imidazo-/5,1-d/-1,2,3,5-tetrazin-4-onderivat med terapeutisk verkan.

Country Status (29)

Country Link
JP (1) JPS5843975A (fi)
KR (1) KR890000094B1 (fi)
AT (1) AT380256B (fi)
AU (1) AU571430B2 (fi)
BE (1) BE894175A (fi)
CA (1) CA1197247A (fi)
CH (1) CH655114A5 (fi)
DE (2) DE19975037I2 (fi)
DK (1) DK161147C (fi)
ES (1) ES8400438A1 (fi)
FI (1) FI73434C (fi)
FR (1) FR2511679A1 (fi)
GB (1) GB2104522B (fi)
GE (1) GEP19960641B (fi)
GR (1) GR76863B (fi)
HU (1) HU186107B (fi)
IE (1) IE53408B1 (fi)
IL (1) IL66606A (fi)
IT (1) IT1152505B (fi)
LT (1) LT2436B (fi)
LU (1) LU84347A1 (fi)
LV (2) LV5511A3 (fi)
NL (2) NL192739C (fi)
NZ (1) NZ201668A (fi)
OA (1) OA07174A (fi)
SE (1) SE448543B (fi)
SU (1) SU1447284A3 (fi)
UA (1) UA5971A1 (fi)
ZA (1) ZA826120B (fi)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260291A (en) * 1981-08-24 1993-11-09 Cancer Research Campaign Technology Limited Tetrazine derivatives
FR2531958B1 (fr) * 1982-08-17 1986-10-31 May & Baker Ltd Nouveaux derive
GB2125402B (en) * 1982-08-17 1985-11-13 May & Baker Ltd New tetrazine derivatives
US4517182A (en) * 1983-05-24 1985-05-14 Warner-Lambert Company 3-(Haloethyl)-4-oxopyrazolo-[5,1-d]-1,2,3,5-tetrazine-8-carboxamide composition
GB8616125D0 (en) * 1986-07-02 1986-08-06 May & Baker Ltd Compositions of matter
AU622330B2 (en) * 1989-06-23 1992-04-02 Takeda Chemical Industries Ltd. Condensed heterocyclic compounds having a nitrogen atom in the bridgehead for use as fungicides
EP2275425A1 (en) * 2003-12-30 2011-01-19 Chemagis Ltd. Novel crystalline forms of temozolomide
EP1845973B1 (en) 2005-01-21 2015-08-12 Astex Therapeutics Limited Pharmaceutical compounds
AR060635A1 (es) 2006-04-27 2008-07-02 Banyu Pharma Co Ltd Derivados de 1,2-dihidro-3h-pirazolo[3,4-d]pirimidin-3-ona, composiciones farmaceuticas que los comprenden y su uso en el tratamiento del cancer
JP2008081492A (ja) 2006-08-31 2008-04-10 Banyu Pharmaceut Co Ltd オーロラａ選択的阻害作用を有する新規アミノピリジン誘導体
EP2073807A1 (en) 2006-10-12 2009-07-01 Astex Therapeutics Limited Pharmaceutical combinations
US8916552B2 (en) 2006-10-12 2014-12-23 Astex Therapeutics Limited Pharmaceutical combinations
JPWO2009054332A1 (ja) 2007-10-23 2011-03-03 萬有製薬株式会社 ピリドン置換ジヒドロピラゾロピリミジノン誘導体
PE20091101A1 (es) 2007-12-18 2009-07-26 Pharminox Ltd AMIDAS DE ACIDO 3-SUBSTITUIDO-4-OXO-3,4-DIHIDRO-IMIDAZO[5,1-d] [1,2,3,5-TETRACINA-8-CARBOXILICO Y SU EMPLEO
BRPI0921194A2 (pt) * 2008-11-24 2015-08-25 Reliance Life Sciences Pvt Ltd Processo para preparação de derivados de tetrazina
US8481503B2 (en) 2009-03-06 2013-07-09 Merck Sharp & Dohme Corp. Combination cancer therapy with an AKT inhibitor and other anticancer agents
WO2010149968A1 (en) 2009-06-23 2010-12-29 Pharminox Limited 3-substituted-8-substituted-3h imidazo[5,1-d][1,2,3,5-tetrazin-4-one compounds and their use
RU2462466C1 (ru) * 2011-06-24 2012-09-27 Автономная Некоммерческая Организация "Научно-Исследовательский Центр Биотехнологии Антибиотиков И Других Биологически Активных Веществ "Биоан" Замещенные азоло[1,2,4,5]тетразины - ингибиторы актинобактериальных серин-треониновых протеинкиназ
EP2766041B1 (en) 2011-10-12 2018-12-05 Children's Medical Center Corporation Combinatorial compositions and methods of treating hemoglobinopathies
BR112018068565A2 (pt) 2016-03-15 2019-02-12 Oryzon Genomics, S.A. combinações de inibidores de lsd1 para uso no tratamento de tumores sólidos
KR101847342B1 (ko) * 2017-05-08 2018-04-11 (주)센텍코리아 웨어러블 체지방 연소량 측정기

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2932305A1 (de) * 1979-08-09 1981-02-26 Basf Ag Azolo- eckige klammer auf 5,1-d eckige klammer zu - eckige klammer auf 1,2,3,5 eckige klammer zu -tetrazin-4-one und verfahren zur herstellung dieser verbindungen

Also Published As

Publication number Publication date
IL66606A0 (en) 1982-12-31
FI73434C (fi) 1987-10-09
LU84347A1 (fr) 1983-06-07
SE8204817L (sv) 1983-02-25
DE19975037I2 (de) 2001-06-13
JPS5843975A (ja) 1983-03-14
KR890000094B1 (ko) 1989-03-07
FI822921L (fi) 1983-02-25
FI73434B (fi) 1987-06-30
NZ201668A (en) 1985-08-16
AT380256B (de) 1986-05-12
GEP19960641B (en) 1996-11-15
LV5621A3 (lv) 1994-05-10
IE53408B1 (en) 1988-11-09
DK377882A (da) 1983-02-25
GB2104522B (en) 1985-06-12
ZA826120B (en) 1983-07-27
IE822026L (en) 1983-02-24
FR2511679A1 (fr) 1983-02-25
BE894175A (fr) 1983-02-23
DE3231255C2 (fi) 1992-02-27
NL990010I2 (nl) 1999-09-01
SE8204817D0 (sv) 1982-08-23
DK161147B (da) 1991-06-03
OA07174A (fr) 1984-04-30
ATA319182A (de) 1985-09-15
IT1152505B (it) 1987-01-07
CA1197247A (fr) 1985-11-26
CH655114A5 (fr) 1986-03-27
GR76863B (fi) 1984-09-04
SE448543B (sv) 1987-03-02
NL192739B (nl) 1997-09-01
AU571430B2 (en) 1988-04-21
DK161147C (da) 1991-11-18
AU8749382A (en) 1983-03-03
LT2436B (lt) 1994-02-15
DE3231255A1 (de) 1983-03-03
NL192739C (nl) 1998-01-06
HU186107B (en) 1985-06-28
ES515176A0 (es) 1983-11-01
FR2511679B1 (fi) 1985-02-01
SU1447284A3 (ru) 1988-12-23
NL990010I1 (nl) 1999-07-01
NL8203286A (nl) 1983-03-16
UA5971A1 (uk) 1994-12-29
IT8222938A0 (it) 1982-08-23
JPH045029B2 (fi) 1992-01-30
ES8400438A1 (es) 1983-11-01
IL66606A (en) 1987-07-31
GB2104522A (en) 1983-03-09
KR840001175A (ko) 1984-03-28
LV5511A3 (lv) 1994-03-10

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Owner name: CANCER RESEARCH CAMPAIGN TECHNOLOGY

SPCG Supplementary protection certificate granted

Spc suppl protection certif: L114

Extension date: 20070822

MA Patent expired

Owner name: CANCER RESEARCH CAMPAIGN TECHNOLOGY