NL990010I2 - Ä3HÜ-imidazo-Ä5,1-dÜ-1,2,3,5-tetrazine-4-on derivaten en farmaceutische samenstellingen, die deze d erivaten bevatten. - Google Patents

Ä3HÜ-imidazo-Ä5,1-dÜ-1,2,3,5-tetrazine-4-on derivaten en farmaceutische samenstellingen, die deze d erivaten bevatten.

Info

Publication number
NL990010I2
NL990010I2 NL990010C NL990010C NL990010I2 NL 990010 I2 NL990010 I2 NL 990010I2 NL 990010 C NL990010 C NL 990010C NL 990010 C NL990010 C NL 990010C NL 990010 I2 NL990010 I2 NL 990010I2
Authority
NL
Netherlands
Prior art keywords
derivatives
ä3hü
tetrazine
imidazo
pharmaceutical compositions
Prior art date
Application number
NL990010C
Other languages
English (en)
Other versions
NL990010I1 (nl
Original Assignee
Cancer Res Campaign Tech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cancer Res Campaign Tech filed Critical Cancer Res Campaign Tech
Publication of NL990010I1 publication Critical patent/NL990010I1/nl
Publication of NL990010I2 publication Critical patent/NL990010I2/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
NL990010C 1981-08-24 1999-04-01 Ä3HÜ-imidazo-Ä5,1-dÜ-1,2,3,5-tetrazine-4-on derivaten en farmaceutische samenstellingen, die deze d erivaten bevatten. NL990010I2 (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8125791 1981-08-24

Publications (2)

Publication Number Publication Date
NL990010I1 NL990010I1 (nl) 1999-07-01
NL990010I2 true NL990010I2 (nl) 1999-09-01

Family

ID=10524141

Family Applications (2)

Application Number Title Priority Date Filing Date
NL8203286A NL192739C (nl) 1981-08-24 1982-08-23 £3H|-imidazo-£5,1-d|-1,2,3,5-tetrazine-4-on derivaten en farmaceutische samenstellingen, die deze derivaten bevatten.
NL990010C NL990010I2 (nl) 1981-08-24 1999-04-01 Ä3HÜ-imidazo-Ä5,1-dÜ-1,2,3,5-tetrazine-4-on derivaten en farmaceutische samenstellingen, die deze d erivaten bevatten.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NL8203286A NL192739C (nl) 1981-08-24 1982-08-23 £3H|-imidazo-£5,1-d|-1,2,3,5-tetrazine-4-on derivaten en farmaceutische samenstellingen, die deze derivaten bevatten.

Country Status (29)

Country Link
JP (1) JPS5843975A (nl)
KR (1) KR890000094B1 (nl)
AT (1) AT380256B (nl)
AU (1) AU571430B2 (nl)
BE (1) BE894175A (nl)
CA (1) CA1197247A (nl)
CH (1) CH655114A5 (nl)
DE (2) DE3231255A1 (nl)
DK (1) DK161147C (nl)
ES (1) ES515176A0 (nl)
FI (1) FI73434C (nl)
FR (1) FR2511679A1 (nl)
GB (1) GB2104522B (nl)
GE (1) GEP19960641B (nl)
GR (1) GR76863B (nl)
HU (1) HU186107B (nl)
IE (1) IE53408B1 (nl)
IL (1) IL66606A (nl)
IT (1) IT1152505B (nl)
LT (1) LT2436B (nl)
LU (1) LU84347A1 (nl)
LV (2) LV5511A3 (nl)
NL (2) NL192739C (nl)
NZ (1) NZ201668A (nl)
OA (1) OA07174A (nl)
SE (1) SE448543B (nl)
SU (1) SU1447284A3 (nl)
UA (1) UA5971A1 (nl)
ZA (1) ZA826120B (nl)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260291A (en) * 1981-08-24 1993-11-09 Cancer Research Campaign Technology Limited Tetrazine derivatives
FR2531958B1 (fr) * 1982-08-17 1986-10-31 May & Baker Ltd Nouveaux derive
GB2125402B (en) * 1982-08-17 1985-11-13 May & Baker Ltd New tetrazine derivatives
US4517182A (en) * 1983-05-24 1985-05-14 Warner-Lambert Company 3-(Haloethyl)-4-oxopyrazolo-[5,1-d]-1,2,3,5-tetrazine-8-carboxamide composition
GB8616125D0 (en) * 1986-07-02 1986-08-06 May & Baker Ltd Compositions of matter
AU622330B2 (en) * 1989-06-23 1992-04-02 Takeda Chemical Industries Ltd. Condensed heterocyclic compounds having a nitrogen atom in the bridgehead for use as fungicides
CZ292102B6 (cs) * 1995-09-25 2003-07-16 Sanofi-Synthelabo Inc. Vodný parenterální prostředek pro léčbu rakovinových nádorů
EP1706407A2 (en) 2003-12-30 2006-10-04 Chemagis Ltd. Novel crystalline forms of temozolomide
KR101346886B1 (ko) 2005-01-21 2014-01-02 아스텍스 테라퓨틱스 리미티드 제약 화합물
AR060635A1 (es) 2006-04-27 2008-07-02 Banyu Pharma Co Ltd Derivados de 1,2-dihidro-3h-pirazolo[3,4-d]pirimidin-3-ona, composiciones farmaceuticas que los comprenden y su uso en el tratamiento del cancer
JP2008081492A (ja) 2006-08-31 2008-04-10 Banyu Pharmaceut Co Ltd オーロラａ選択的阻害作用を有する新規アミノピリジン誘導体
JP5528807B2 (ja) 2006-10-12 2014-06-25 アステックス、セラピューティックス、リミテッド 複合薬剤
JP5528806B2 (ja) 2006-10-12 2014-06-25 アステックス、セラピューティックス、リミテッド 複合薬剤
WO2009054332A1 (ja) 2007-10-23 2009-04-30 Banyu Pharmaceutical Co., Ltd. ピリドン置換ジヒドロピラゾロピリミジノン誘導体
PE20091101A1 (es) * 2007-12-18 2009-07-26 Pharminox Ltd AMIDAS DE ACIDO 3-SUBSTITUIDO-4-OXO-3,4-DIHIDRO-IMIDAZO[5,1-d] [1,2,3,5-TETRACINA-8-CARBOXILICO Y SU EMPLEO
CN102256978A (zh) * 2008-11-24 2011-11-23 利莱恩斯生命科学有限公司 制备四嗪衍生物的工艺
WO2010101734A1 (en) 2009-03-06 2010-09-10 Merck Sharp & Dohme Corp. Combination cancer therapy with an akt inhibitor and other anticancer agents
JP2012530775A (ja) 2009-06-23 2012-12-06 ファーミノックス リミテッド ３−置換−８−置換−３Ｈ−イミダゾ［５，１−ｄ］［１，２，３，５−テトラジン−４−オン化合物及びその使用
RU2462466C1 (ru) * 2011-06-24 2012-09-27 Автономная Некоммерческая Организация "Научно-Исследовательский Центр Биотехнологии Антибиотиков И Других Биологически Активных Веществ "Биоан" Замещенные азоло[1,2,4,5]тетразины - ингибиторы актинобактериальных серин-треониновых протеинкиназ
US20140271657A1 (en) 2011-10-12 2014-09-18 Children's Medical Center Corporation Combinatorial compositions and methods of treating hemoglobinopathies
AU2017233898B2 (en) 2016-03-15 2022-12-15 Oryzon Genomics, S.A. Combinations of LSD1 inhibitors for use in the treatment of solid tumors
KR101847342B1 (ko) * 2017-05-08 2018-04-11 (주)센텍코리아 웨어러블 체지방 연소량 측정기

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2932305A1 (de) * 1979-08-09 1981-02-26 Basf Ag Azolo- eckige klammer auf 5,1-d eckige klammer zu - eckige klammer auf 1,2,3,5 eckige klammer zu -tetrazin-4-one und verfahren zur herstellung dieser verbindungen

Also Published As

Publication number Publication date
DK161147B (da) 1991-06-03
FI822921A0 (fi) 1982-08-23
DE3231255A1 (de) 1983-03-03
DE19975037I2 (de) 2001-06-13
FI822921L (fi) 1983-02-25
IL66606A0 (en) 1982-12-31
CH655114A5 (fr) 1986-03-27
SE8204817L (sv) 1983-02-25
SU1447284A3 (ru) 1988-12-23
SE8204817D0 (sv) 1982-08-23
AU571430B2 (en) 1988-04-21
IE822026L (en) 1983-02-24
FR2511679B1 (nl) 1985-02-01
IT8222938A1 (it) 1984-02-23
GB2104522B (en) 1985-06-12
FR2511679A1 (fr) 1983-02-25
NL990010I1 (nl) 1999-07-01
ZA826120B (en) 1983-07-27
CA1197247A (fr) 1985-11-26
IL66606A (en) 1987-07-31
LV5621A3 (lv) 1994-05-10
IT1152505B (it) 1987-01-07
DK161147C (da) 1991-11-18
LU84347A1 (fr) 1983-06-07
DK377882A (da) 1983-02-25
GB2104522A (en) 1983-03-09
NL192739B (nl) 1997-09-01
FI73434B (fi) 1987-06-30
IT8222938A0 (it) 1982-08-23
KR840001175A (ko) 1984-03-28
GEP19960641B (en) 1996-11-15
NL192739C (nl) 1998-01-06
AU8749382A (en) 1983-03-03
AT380256B (de) 1986-05-12
GR76863B (nl) 1984-09-04
BE894175A (fr) 1983-02-23
UA5971A1 (uk) 1994-12-29
JPH045029B2 (nl) 1992-01-30
NZ201668A (en) 1985-08-16
IE53408B1 (en) 1988-11-09
SE448543B (sv) 1987-03-02
LT2436B (lt) 1994-02-15
OA07174A (fr) 1984-04-30
ES8400438A1 (es) 1983-11-01
ES515176A0 (es) 1983-11-01
HU186107B (en) 1985-06-28
JPS5843975A (ja) 1983-03-14
NL8203286A (nl) 1983-03-16
FI73434C (fi) 1987-10-09
ATA319182A (de) 1985-09-15
KR890000094B1 (ko) 1989-03-07
LV5511A3 (lv) 1994-03-10
DE3231255C2 (nl) 1992-02-27

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