AU571430B2 - Imidazo(5,1-d) 1,2,3,5-tetrazin-4-ones - Google Patents

Imidazo(5,1-d) 1,2,3,5-tetrazin-4-ones

Info

Publication number
AU571430B2
AU571430B2 AU87493/82A AU8749382A AU571430B2 AU 571430 B2 AU571430 B2 AU 571430B2 AU 87493/82 A AU87493/82 A AU 87493/82A AU 8749382 A AU8749382 A AU 8749382A AU 571430 B2 AU571430 B2 AU 571430B2
Authority
AU
Australia
Prior art keywords
tetrazin
imidazo
ones
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired, expires
Application number
AU87493/82A
Other languages
English (en)
Other versions
AU8749382A (en
Inventor
Edward Lunt
Malcolm Francis Graham Stevens
Robert Stone
Kenneth Robert Harry Wooldridge
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cancer Research Campaign Technology Ltd
Original Assignee
May and Baker Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by May and Baker Ltd filed Critical May and Baker Ltd
Publication of AU8749382A publication Critical patent/AU8749382A/en
Application granted granted Critical
Publication of AU571430B2 publication Critical patent/AU571430B2/en
Assigned to CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED reassignment CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED Alteration of Name(s) in Register under S187 Assignors: MAY AND BAKER LTD.
Adjusted expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
AU87493/82A 1981-08-24 1982-08-23 Imidazo(5,1-d) 1,2,3,5-tetrazin-4-ones Expired AU571430B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8125791 1981-08-24
GB8125791 1981-08-24

Publications (2)

Publication Number Publication Date
AU8749382A AU8749382A (en) 1983-03-03
AU571430B2 true AU571430B2 (en) 1988-04-21

Family

ID=10524141

Family Applications (1)

Application Number Title Priority Date Filing Date
AU87493/82A Expired AU571430B2 (en) 1981-08-24 1982-08-23 Imidazo(5,1-d) 1,2,3,5-tetrazin-4-ones

Country Status (29)

Country Link
JP (1) JPS5843975A (nl)
KR (1) KR890000094B1 (nl)
AT (1) AT380256B (nl)
AU (1) AU571430B2 (nl)
BE (1) BE894175A (nl)
CA (1) CA1197247A (nl)
CH (1) CH655114A5 (nl)
DE (2) DE19975037I2 (nl)
DK (1) DK161147C (nl)
ES (1) ES515176A0 (nl)
FI (1) FI73434C (nl)
FR (1) FR2511679A1 (nl)
GB (1) GB2104522B (nl)
GE (1) GEP19960641B (nl)
GR (1) GR76863B (nl)
HU (1) HU186107B (nl)
IE (1) IE53408B1 (nl)
IL (1) IL66606A (nl)
IT (1) IT1152505B (nl)
LT (1) LT2436B (nl)
LU (1) LU84347A1 (nl)
LV (2) LV5511A3 (nl)
NL (2) NL192739C (nl)
NZ (1) NZ201668A (nl)
OA (1) OA07174A (nl)
SE (1) SE448543B (nl)
SU (1) SU1447284A3 (nl)
UA (1) UA5971A1 (nl)
ZA (1) ZA826120B (nl)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260291A (en) * 1981-08-24 1993-11-09 Cancer Research Campaign Technology Limited Tetrazine derivatives

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2125402B (en) * 1982-08-17 1985-11-13 May & Baker Ltd New tetrazine derivatives
GR78688B (nl) * 1982-08-17 1984-09-27 May & Baker Ltd
US4517182A (en) * 1983-05-24 1985-05-14 Warner-Lambert Company 3-(Haloethyl)-4-oxopyrazolo-[5,1-d]-1,2,3,5-tetrazine-8-carboxamide composition
GB8616125D0 (en) * 1986-07-02 1986-08-06 May & Baker Ltd Compositions of matter
AU622330B2 (en) * 1989-06-23 1992-04-02 Takeda Chemical Industries Ltd. Condensed heterocyclic compounds having a nitrogen atom in the bridgehead for use as fungicides
EP1706407A2 (en) 2003-12-30 2006-10-04 Chemagis Ltd. Novel crystalline forms of temozolomide
AU2006207325B2 (en) 2005-01-21 2012-08-16 Astex Therapeutics Limited Pharmaceutical compounds
AR060635A1 (es) 2006-04-27 2008-07-02 Banyu Pharma Co Ltd Derivados de 1,2-dihidro-3h-pirazolo[3,4-d]pirimidin-3-ona, composiciones farmaceuticas que los comprenden y su uso en el tratamiento del cancer
JP2008081492A (ja) 2006-08-31 2008-04-10 Banyu Pharmaceut Co Ltd オーロラａ選択的阻害作用を有する新規アミノピリジン誘導体
US8883790B2 (en) 2006-10-12 2014-11-11 Astex Therapeutics Limited Pharmaceutical combinations
US8916552B2 (en) 2006-10-12 2014-12-23 Astex Therapeutics Limited Pharmaceutical combinations
CA2703489A1 (en) 2007-10-23 2009-04-30 Banyu Pharmaceutical Co., Ltd. Pyridone-substituted-dihydropyrazolopyrimidinone derivative
PE20091101A1 (es) * 2007-12-18 2009-07-26 Pharminox Ltd AMIDAS DE ACIDO 3-SUBSTITUIDO-4-OXO-3,4-DIHIDRO-IMIDAZO[5,1-d] [1,2,3,5-TETRACINA-8-CARBOXILICO Y SU EMPLEO
CA2744560A1 (en) * 2008-11-24 2010-05-27 Reliance Life Sciences Pvt. Ltd. Process for the preparation of tetrazine derivatives
WO2010101734A1 (en) 2009-03-06 2010-09-10 Merck Sharp & Dohme Corp. Combination cancer therapy with an akt inhibitor and other anticancer agents
AU2010264339A1 (en) 2009-06-23 2011-12-22 Pharminox Limited 3-substituted-8-substituted-3H imidazo[5,1-d][1,2,3,5-tetrazin-4-one compounds and their use
RU2462466C1 (ru) * 2011-06-24 2012-09-27 Автономная Некоммерческая Организация "Научно-Исследовательский Центр Биотехнологии Антибиотиков И Других Биологически Активных Веществ "Биоан" Замещенные азоло[1,2,4,5]тетразины - ингибиторы актинобактериальных серин-треониновых протеинкиназ
WO2013055985A1 (en) 2011-10-12 2013-04-18 Children's Medical Center Corporation Combinatorial compositions and methods of treating hemoglobinopathies
SG10201913331VA (en) 2016-03-15 2020-03-30 Oryzon Genomics Sa Combinations of lsd1 inhibitors for use in the treatment of solid tumors
KR101847342B1 (ko) * 2017-05-08 2018-04-11 (주)센텍코리아 웨어러블 체지방 연소량 측정기

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2932305A1 (de) * 1979-08-09 1981-02-26 Basf Ag Azolo- eckige klammer auf 5,1-d eckige klammer zu - eckige klammer auf 1,2,3,5 eckige klammer zu -tetrazin-4-one und verfahren zur herstellung dieser verbindungen

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260291A (en) * 1981-08-24 1993-11-09 Cancer Research Campaign Technology Limited Tetrazine derivatives

Also Published As

Publication number Publication date
JPH045029B2 (nl) 1992-01-30
DK161147B (da) 1991-06-03
LU84347A1 (fr) 1983-06-07
NL192739B (nl) 1997-09-01
ZA826120B (en) 1983-07-27
ATA319182A (de) 1985-09-15
DK161147C (da) 1991-11-18
NZ201668A (en) 1985-08-16
BE894175A (fr) 1983-02-23
FR2511679A1 (fr) 1983-02-25
LV5621A3 (lv) 1994-05-10
KR890000094B1 (ko) 1989-03-07
KR840001175A (ko) 1984-03-28
UA5971A1 (uk) 1994-12-29
SE8204817D0 (sv) 1982-08-23
SE448543B (sv) 1987-03-02
ES8400438A1 (es) 1983-11-01
NL8203286A (nl) 1983-03-16
HU186107B (en) 1985-06-28
GB2104522B (en) 1985-06-12
GB2104522A (en) 1983-03-09
SU1447284A3 (ru) 1988-12-23
LV5511A3 (lv) 1994-03-10
AT380256B (de) 1986-05-12
LT2436B (lt) 1994-02-15
DE3231255C2 (nl) 1992-02-27
AU8749382A (en) 1983-03-03
CH655114A5 (fr) 1986-03-27
IE822026L (en) 1983-02-24
NL990010I2 (nl) 1999-09-01
FI822921A0 (fi) 1982-08-23
DE19975037I2 (de) 2001-06-13
JPS5843975A (ja) 1983-03-14
IL66606A (en) 1987-07-31
FI73434B (fi) 1987-06-30
OA07174A (fr) 1984-04-30
IE53408B1 (en) 1988-11-09
IT8222938A0 (it) 1982-08-23
FR2511679B1 (nl) 1985-02-01
NL192739C (nl) 1998-01-06
IL66606A0 (en) 1982-12-31
ES515176A0 (es) 1983-11-01
GEP19960641B (en) 1996-11-15
IT1152505B (it) 1987-01-07
DE3231255A1 (de) 1983-03-03
GR76863B (nl) 1984-09-04
SE8204817L (sv) 1983-02-25
NL990010I1 (nl) 1999-07-01
FI73434C (fi) 1987-10-09
CA1197247A (fr) 1985-11-26
DK377882A (da) 1983-02-25
FI822921L (fi) 1983-02-25

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Legal Events

Date Code Title Description
NDB Extension of term for standard patent granted (sect.76)

Free format text: PRODUCT NAME: TEMOZOLOMIDE

Extension date: 20070823