FI822921L - Foerfarande foer framstaellning av /3h/-imidazo-/5,1-d/-1,2,3,5-tetrazin-4-onderivat med terapeutisverkan - Google Patents

Foerfarande foer framstaellning av /3h/-imidazo-/5,1-d/-1,2,3,5-tetrazin-4-onderivat med terapeutisverkan

Info

Publication number
FI822921L
FI822921L FI822921A FI822921A FI822921L FI 822921 L FI822921 L FI 822921L FI 822921 A FI822921 A FI 822921A FI 822921 A FI822921 A FI 822921A FI 822921 L FI822921 L FI 822921L
Authority
FI
Finland
Prior art keywords
terapeutisverkan
onderivat
framstation
tetrazine
imidazo
Prior art date
Application number
FI822921A
Other languages
English (en)
Other versions
FI73434B (fi
FI822921A0 (fi
FI73434C (fi
Inventor
Edward Lunt
Malcolm Francis Graham Stevens
Robert Stone
Kenneth Robert Harr Wooldringe
Original Assignee
May & Baker Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by May & Baker Ltd filed Critical May & Baker Ltd
Publication of FI822921A0 publication Critical patent/FI822921A0/fi
Publication of FI822921L publication Critical patent/FI822921L/fi
Publication of FI73434B publication Critical patent/FI73434B/fi
Application granted granted Critical
Publication of FI73434C publication Critical patent/FI73434C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
FI822921A 1981-08-24 1982-08-23 Foerfarande foer framstaellning av /3h/-imidazo-/5,1-d/-1,2,3,5-tetrazin-4-onderivat med terapeutisk verkan. FI73434C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8125791 1981-08-24
GB8125791 1981-08-24

Publications (4)

Publication Number Publication Date
FI822921A0 FI822921A0 (fi) 1982-08-23
FI822921L true FI822921L (fi) 1983-02-25
FI73434B FI73434B (fi) 1987-06-30
FI73434C FI73434C (fi) 1987-10-09

Family

ID=10524141

Family Applications (1)

Application Number Title Priority Date Filing Date
FI822921A FI73434C (fi) 1981-08-24 1982-08-23 Foerfarande foer framstaellning av /3h/-imidazo-/5,1-d/-1,2,3,5-tetrazin-4-onderivat med terapeutisk verkan.

Country Status (29)

Country Link
JP (1) JPS5843975A (fi)
KR (1) KR890000094B1 (fi)
AT (1) AT380256B (fi)
AU (1) AU571430B2 (fi)
BE (1) BE894175A (fi)
CA (1) CA1197247A (fi)
CH (1) CH655114A5 (fi)
DE (2) DE19975037I2 (fi)
DK (1) DK161147C (fi)
ES (1) ES515176A0 (fi)
FI (1) FI73434C (fi)
FR (1) FR2511679A1 (fi)
GB (1) GB2104522B (fi)
GE (1) GEP19960641B (fi)
GR (1) GR76863B (fi)
HU (1) HU186107B (fi)
IE (1) IE53408B1 (fi)
IL (1) IL66606A (fi)
IT (1) IT1152505B (fi)
LT (1) LT2436B (fi)
LU (1) LU84347A1 (fi)
LV (2) LV5511A3 (fi)
NL (2) NL192739C (fi)
NZ (1) NZ201668A (fi)
OA (1) OA07174A (fi)
SE (1) SE448543B (fi)
SU (1) SU1447284A3 (fi)
UA (1) UA5971A1 (fi)
ZA (1) ZA826120B (fi)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260291A (en) * 1981-08-24 1993-11-09 Cancer Research Campaign Technology Limited Tetrazine derivatives
GR78688B (fi) * 1982-08-17 1984-09-27 May & Baker Ltd
GB2125402B (en) * 1982-08-17 1985-11-13 May & Baker Ltd New tetrazine derivatives
US4517182A (en) * 1983-05-24 1985-05-14 Warner-Lambert Company 3-(Haloethyl)-4-oxopyrazolo-[5,1-d]-1,2,3,5-tetrazine-8-carboxamide composition
GB8616125D0 (en) * 1986-07-02 1986-08-06 May & Baker Ltd Compositions of matter
AU622330B2 (en) * 1989-06-23 1992-04-02 Takeda Chemical Industries Ltd. Condensed heterocyclic compounds having a nitrogen atom in the bridgehead for use as fungicides
WO2005063757A2 (en) * 2003-12-30 2005-07-14 Chemagis Ltd. Novel crystalline forms of temozolomide
US20090036435A1 (en) 2005-01-21 2009-02-05 Astex Therapeutics Limited Pharmaceutical Compounds
AR060635A1 (es) 2006-04-27 2008-07-02 Banyu Pharma Co Ltd Derivados de 1,2-dihidro-3h-pirazolo[3,4-d]pirimidin-3-ona, composiciones farmaceuticas que los comprenden y su uso en el tratamiento del cancer
JP2008081492A (ja) 2006-08-31 2008-04-10 Banyu Pharmaceut Co Ltd オーロラａ選択的阻害作用を有する新規アミノピリジン誘導体
JP5528806B2 (ja) 2006-10-12 2014-06-25 アステックス、セラピューティックス、リミテッド 複合薬剤
WO2008044045A1 (en) 2006-10-12 2008-04-17 Astex Therapeutics Limited Pharmaceutical combinations
WO2009054332A1 (ja) 2007-10-23 2009-04-30 Banyu Pharmaceutical Co., Ltd. ピリドン置換ジヒドロピラゾロピリミジノン誘導体
PE20091101A1 (es) * 2007-12-18 2009-07-26 Pharminox Ltd AMIDAS DE ACIDO 3-SUBSTITUIDO-4-OXO-3,4-DIHIDRO-IMIDAZO[5,1-d] [1,2,3,5-TETRACINA-8-CARBOXILICO Y SU EMPLEO
US8716471B2 (en) * 2008-11-24 2014-05-06 Reliance Life Sciences Pvt. Ltd. Process for the preparation of tetrazine derivatives
WO2010101734A1 (en) 2009-03-06 2010-09-10 Merck Sharp & Dohme Corp. Combination cancer therapy with an akt inhibitor and other anticancer agents
US9024018B2 (en) 2009-06-23 2015-05-05 Pharminox Limited 3-substituted-8-substituted-3H-imidazo[5,1-d][1,2,3,5]tetrazin-4-one compounds and their use
RU2462466C1 (ru) * 2011-06-24 2012-09-27 Автономная Некоммерческая Организация "Научно-Исследовательский Центр Биотехнологии Антибиотиков И Других Биологически Активных Веществ "Биоан" Замещенные азоло[1,2,4,5]тетразины - ингибиторы актинобактериальных серин-треониновых протеинкиназ
EP2766041B1 (en) 2011-10-12 2018-12-05 Children's Medical Center Corporation Combinatorial compositions and methods of treating hemoglobinopathies
CA3017411A1 (en) 2016-03-15 2017-09-21 Oryzon Genomics, S.A. Combinations of lsd1 inhibitors for use in the treatment of solid tumors
KR101847342B1 (ko) * 2017-05-08 2018-04-11 (주)센텍코리아 웨어러블 체지방 연소량 측정기

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2932305A1 (de) * 1979-08-09 1981-02-26 Basf Ag Azolo- eckige klammer auf 5,1-d eckige klammer zu - eckige klammer auf 1,2,3,5 eckige klammer zu -tetrazin-4-one und verfahren zur herstellung dieser verbindungen

Also Published As

Publication number Publication date
FI73434B (fi) 1987-06-30
SE8204817D0 (sv) 1982-08-23
BE894175A (fr) 1983-02-23
AT380256B (de) 1986-05-12
NL8203286A (nl) 1983-03-16
DK377882A (da) 1983-02-25
DE3231255C2 (fi) 1992-02-27
GR76863B (fi) 1984-09-04
FI822921A0 (fi) 1982-08-23
LV5621A3 (lv) 1994-05-10
SU1447284A3 (ru) 1988-12-23
ES8400438A1 (es) 1983-11-01
SE448543B (sv) 1987-03-02
IT1152505B (it) 1987-01-07
FR2511679B1 (fi) 1985-02-01
FR2511679A1 (fr) 1983-02-25
AU8749382A (en) 1983-03-03
ES515176A0 (es) 1983-11-01
IT8222938A0 (it) 1982-08-23
FI73434C (fi) 1987-10-09
CH655114A5 (fr) 1986-03-27
GB2104522A (en) 1983-03-09
DK161147C (da) 1991-11-18
UA5971A1 (uk) 1994-12-29
LT2436B (lt) 1994-02-15
GB2104522B (en) 1985-06-12
SE8204817L (sv) 1983-02-25
NL192739B (nl) 1997-09-01
IL66606A (en) 1987-07-31
NL192739C (nl) 1998-01-06
GEP19960641B (en) 1996-11-15
OA07174A (fr) 1984-04-30
AU571430B2 (en) 1988-04-21
NL990010I1 (nl) 1999-07-01
IL66606A0 (en) 1982-12-31
KR890000094B1 (ko) 1989-03-07
DE19975037I2 (de) 2001-06-13
LV5511A3 (lv) 1994-03-10
IE53408B1 (en) 1988-11-09
IE822026L (en) 1983-02-24
DE3231255A1 (de) 1983-03-03
HU186107B (en) 1985-06-28
JPS5843975A (ja) 1983-03-14
LU84347A1 (fr) 1983-06-07
DK161147B (da) 1991-06-03
ATA319182A (de) 1985-09-15
ZA826120B (en) 1983-07-27
NZ201668A (en) 1985-08-16
CA1197247A (fr) 1985-11-26
KR840001175A (ko) 1984-03-28
NL990010I2 (nl) 1999-09-01
JPH045029B2 (fi) 1992-01-30

Similar Documents

Publication Publication Date Title
FI822921L (fi) Foerfarande foer framstaellning av /3h/-imidazo-/5,1-d/-1,2,3,5-tetrazin-4-onderivat med terapeutisverkan
AR231138A1 (es) Procedimiento para preparar derivados de 6(7)-oxiranil-metoxi-7(6)-metoxi o oxiranil-metoxi-quinazolina
NO820083L (no) Fremgangsmaate ved fremstilling av d-fenylalanyl-l-propyl-l-argininaldehydsulfat
NO821137L (no) Fremgangsmaate for fremstilling av tertiaere alkyletere
YU43077B (en) Process for the manufacture of substituted 1,2-diaminocyclo-butene-3,4-diones
IT1150897B (it) Procedimento per la fabbricazione di vulcanizzati
IT1152146B (it) Procedimento per la produzione di nerofumo
NO851524L (no) Fremgangsmaate for fremstilling av fenetanolamin-forbindelser
NO824019L (no) Fremgangsmaate for fremstilling av alfa-galaktooksidase
RO86213A (ro) Procedeu pentru prepararea izobutenei
DE3278474D1 (en) Process for the preparation of di-galactose derivatives
NO823637L (no) Fremgangsmaate for fremstilling av eburnamoninderivater
NO822634L (no) Fremgangsmaate for fremstilling av cefemderivater.
IT1154275B (it) Procedimento per la produzione di disolfuri di tiurame
FI820598L (fi) Foerfarande foer framstaellning av treo-2-hydroxi-3-(4-methoxifenyl)-3-(2-nitrofenyltio)-propionsyraester
YU49482A (en) Process for the manufacture of guanidine derivatives
NO820010L (no) Organopolysiloksan-blandinger egnet for fremstilling av elastomerer
GB2152051B (en) Process for the preparation of azetidinone derivatives
EP0155710A3 (en) Process for the preparation of derivatives of polyethoxypropanesulfonates
PT74254A (en) Process for the preparation of pyridinyl-substituted-benzimidazole derivatives
RO85557A (ro) Procedeu pentru prepararea carbonatilor de alchilen
NO820767L (no) Fremgangsmaate for fremstilling av tetrahydropyridinderivater
FI820923L (fi) Foerfarande foer framstaellning av 2-amino-5-(o-sulfamidofenyl)-1,3,4-tiadiazolderivat
JPS57181100A (en) Manufacture of 17 alpha-hydroxy-pregn-4-ene- 3,20-dione derivatives
NO822808L (no) Fremgangsmaate ved fremstilling av decarboxylaseinhiberende fluorerte alkandiaminoderivater

Legal Events

Date Code Title Description
PC Transfer of assignment of patent

Owner name: CANCER RESEARCH CAMPAIGN TECHNOLOGY

SPCG Supplementary protection certificate granted

Spc suppl protection certif: L114

Extension date: 20070822

MA Patent expired

Owner name: CANCER RESEARCH CAMPAIGN TECHNOLOGY