IL66606A - 4-oxo-3h-imizado(5,1-d)1,2,3,5-tetrazine-8-carboxamide derivatives,their preparation and pharmaceutical compositions containing them - Google Patents
4-oxo-3h-imizado(5,1-d)1,2,3,5-tetrazine-8-carboxamide derivatives,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL66606A IL66606A IL66606A IL6660682A IL66606A IL 66606 A IL66606 A IL 66606A IL 66606 A IL66606 A IL 66606A IL 6660682 A IL6660682 A IL 6660682A IL 66606 A IL66606 A IL 66606A
- Authority
- IL
- Israel
- Prior art keywords
- imizado
- tetrazine
- oxo
- preparation
- pharmaceutical compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8125791 | 1981-08-24 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL66606A0 IL66606A0 (en) | 1982-12-31 |
| IL66606A true IL66606A (en) | 1987-07-31 |
Family
ID=10524141
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL66606A IL66606A (en) | 1981-08-24 | 1982-08-12 | 4-oxo-3h-imizado(5,1-d)1,2,3,5-tetrazine-8-carboxamide derivatives,their preparation and pharmaceutical compositions containing them |
Country Status (29)
| Country | Link |
|---|---|
| JP (1) | JPS5843975A (fi) |
| KR (1) | KR890000094B1 (fi) |
| AT (1) | AT380256B (fi) |
| AU (1) | AU571430B2 (fi) |
| BE (1) | BE894175A (fi) |
| CA (1) | CA1197247A (fi) |
| CH (1) | CH655114A5 (fi) |
| DE (2) | DE19975037I2 (fi) |
| DK (1) | DK161147C (fi) |
| ES (1) | ES515176A0 (fi) |
| FI (1) | FI73434C (fi) |
| FR (1) | FR2511679A1 (fi) |
| GB (1) | GB2104522B (fi) |
| GE (1) | GEP19960641B (fi) |
| GR (1) | GR76863B (fi) |
| HU (1) | HU186107B (fi) |
| IE (1) | IE53408B1 (fi) |
| IL (1) | IL66606A (fi) |
| IT (1) | IT1152505B (fi) |
| LT (1) | LT2436B (fi) |
| LU (1) | LU84347A1 (fi) |
| LV (2) | LV5511A3 (fi) |
| NL (2) | NL192739C (fi) |
| NZ (1) | NZ201668A (fi) |
| OA (1) | OA07174A (fi) |
| SE (1) | SE448543B (fi) |
| SU (1) | SU1447284A3 (fi) |
| UA (1) | UA5971A1 (fi) |
| ZA (1) | ZA826120B (fi) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5260291A (en) * | 1981-08-24 | 1993-11-09 | Cancer Research Campaign Technology Limited | Tetrazine derivatives |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2125402B (en) * | 1982-08-17 | 1985-11-13 | May & Baker Ltd | New tetrazine derivatives |
| FR2531958B1 (fr) * | 1982-08-17 | 1986-10-31 | May & Baker Ltd | Nouveaux derive |
| US4517182A (en) * | 1983-05-24 | 1985-05-14 | Warner-Lambert Company | 3-(Haloethyl)-4-oxopyrazolo-[5,1-d]-1,2,3,5-tetrazine-8-carboxamide composition |
| GB8616125D0 (en) * | 1986-07-02 | 1986-08-06 | May & Baker Ltd | Compositions of matter |
| AU622330B2 (en) * | 1989-06-23 | 1992-04-02 | Takeda Chemical Industries Ltd. | Condensed heterocyclic compounds having a nitrogen atom in the bridgehead for use as fungicides |
| CA2552095A1 (en) * | 2003-12-30 | 2005-07-14 | Chemagis Ltd. | Novel crystalline forms of temozolomide |
| CA2594477C (en) | 2005-01-21 | 2016-07-12 | Astex Therapeutics Limited | Pharmaceutical compounds |
| PE20080695A1 (es) | 2006-04-27 | 2008-06-28 | Banyu Pharma Co Ltd | Derivados de dihidropirazolopirimidinona como inhibidores de quinasa weel |
| JP2008081492A (ja) | 2006-08-31 | 2008-04-10 | Banyu Pharmaceut Co Ltd | オーロラａ選択的阻害作用を有する新規アミノピリジン誘導体 |
| EP2073807A1 (en) | 2006-10-12 | 2009-07-01 | Astex Therapeutics Limited | Pharmaceutical combinations |
| US8916552B2 (en) | 2006-10-12 | 2014-12-23 | Astex Therapeutics Limited | Pharmaceutical combinations |
| US8329711B2 (en) | 2007-10-23 | 2012-12-11 | Msd K.K. | Pyridone-substituted-dihydropyrazolopyrimidinone derivative |
| PE20091101A1 (es) * | 2007-12-18 | 2009-07-26 | Pharminox Ltd | AMIDAS DE ACIDO 3-SUBSTITUIDO-4-OXO-3,4-DIHIDRO-IMIDAZO[5,1-d] [1,2,3,5-TETRACINA-8-CARBOXILICO Y SU EMPLEO |
| KR20110111383A (ko) * | 2008-11-24 | 2011-10-11 | 리라이언스 라이프 사이언시스 프라이빗. 리미티드 | 테트라진 유도체의 제조 방법 |
| US8481503B2 (en) | 2009-03-06 | 2013-07-09 | Merck Sharp & Dohme Corp. | Combination cancer therapy with an AKT inhibitor and other anticancer agents |
| JP2012530775A (ja) | 2009-06-23 | 2012-12-06 | ファーミノックス リミテッド | ３−置換−８−置換−３Ｈ−イミダゾ［５，１−ｄ］［１，２，３，５−テトラジン−４−オン化合物及びその使用 |
| RU2462466C1 (ru) * | 2011-06-24 | 2012-09-27 | Автономная Некоммерческая Организация "Научно-Исследовательский Центр Биотехнологии Антибиотиков И Других Биологически Активных Веществ "Биоан" | Замещенные азоло[1,2,4,5]тетразины - ингибиторы актинобактериальных серин-треониновых протеинкиназ |
| US20140271657A1 (en) | 2011-10-12 | 2014-09-18 | Children's Medical Center Corporation | Combinatorial compositions and methods of treating hemoglobinopathies |
| AU2017233898B2 (en) | 2016-03-15 | 2022-12-15 | Oryzon Genomics, S.A. | Combinations of LSD1 inhibitors for use in the treatment of solid tumors |
| KR101847342B1 (ko) * | 2017-05-08 | 2018-04-11 | (주)센텍코리아 | 웨어러블 체지방 연소량 측정기 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2932305A1 (de) * | 1979-08-09 | 1981-02-26 | Basf Ag | Azolo- eckige klammer auf 5,1-d eckige klammer zu - eckige klammer auf 1,2,3,5 eckige klammer zu -tetrazin-4-one und verfahren zur herstellung dieser verbindungen |
-
1982
- 1982-08-05 OA OA57766BISD patent/OA07174A/xx unknown
- 1982-08-12 IL IL66606A patent/IL66606A/xx not_active IP Right Cessation
- 1982-08-23 IE IE2026/82A patent/IE53408B1/en not_active IP Right Cessation
- 1982-08-23 IT IT22938/82A patent/IT1152505B/it active Protection Beyond IP Right Term
- 1982-08-23 DK DK377882A patent/DK161147C/da not_active IP Right Cessation
- 1982-08-23 JP JP57144902A patent/JPS5843975A/ja active Granted
- 1982-08-23 FR FR8214461A patent/FR2511679A1/fr active Granted
- 1982-08-23 SE SE8204817A patent/SE448543B/sv not_active IP Right Cessation
- 1982-08-23 HU HU822708A patent/HU186107B/hu unknown
- 1982-08-23 AU AU87493/82A patent/AU571430B2/en not_active Expired
- 1982-08-23 NZ NZ201668A patent/NZ201668A/en unknown
- 1982-08-23 NL NL8203286A patent/NL192739C/nl not_active IP Right Cessation
- 1982-08-23 UA UA3482389A patent/UA5971A1/uk unknown
- 1982-08-23 ZA ZA826120A patent/ZA826120B/xx unknown
- 1982-08-23 KR KR8203774A patent/KR890000094B1/ko active
- 1982-08-23 CH CH5007/82A patent/CH655114A5/fr not_active IP Right Cessation
- 1982-08-23 DE DE1999175037 patent/DE19975037I2/de active Active
- 1982-08-23 AT AT0319182A patent/AT380256B/de not_active IP Right Cessation
- 1982-08-23 SU SU823482389A patent/SU1447284A3/ru active
- 1982-08-23 CA CA000409950A patent/CA1197247A/fr not_active Expired
- 1982-08-23 FI FI822921A patent/FI73434C/fi not_active IP Right Cessation
- 1982-08-23 ES ES515176A patent/ES515176A0/es active Granted
- 1982-08-23 GB GB08224155A patent/GB2104522B/en not_active Expired
- 1982-08-23 BE BE0/208860A patent/BE894175A/fr not_active IP Right Cessation
- 1982-08-23 GR GR69093A patent/GR76863B/el unknown
- 1982-08-23 DE DE19823231255 patent/DE3231255A1/de active Granted
- 1982-08-23 LU LU84347A patent/LU84347A1/fr unknown
-
1993
- 1993-06-19 LV LV930621A patent/LV5511A3/xx unknown
- 1993-09-29 LT LTRP1286A patent/LT2436B/xx not_active IP Right Cessation
- 1993-11-16 GE GEAP19931653A patent/GEP19960641B/en unknown
- 1993-12-03 LV LV931303A patent/LV5621A3/xx unknown
-
1999
- 1999-04-01 NL NL990010C patent/NL990010I2/nl unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5260291A (en) * | 1981-08-24 | 1993-11-09 | Cancer Research Campaign Technology Limited | Tetrazine derivatives |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| EXP | Patent expired |