SE448543B - /3h/-imidazo/5,1-d/-1,2,3,5-tetrazin-4-onderivat, forfarande for deras framstellning och farmaceutiska kompositioner innehallande desamma - Google Patents

/3h/-imidazo/5,1-d/-1,2,3,5-tetrazin-4-onderivat, forfarande for deras framstellning och farmaceutiska kompositioner innehallande desamma

Info

Publication number
SE448543B
SE448543B SE8204817A SE8204817A SE448543B SE 448543 B SE448543 B SE 448543B SE 8204817 A SE8204817 A SE 8204817A SE 8204817 A SE8204817 A SE 8204817A SE 448543 B SE448543 B SE 448543B
Authority
SE
Sweden
Prior art keywords
group
carbon atoms
groups
general formula
straight
Prior art date
Application number
SE8204817A
Other languages
English (en)
Swedish (sv)
Other versions
SE8204817D0 (sv
SE8204817L (sv
Inventor
E Lunt
M F G Stevens
R Stone
K R H Woolridge
Original Assignee
May & Baker Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by May & Baker Ltd filed Critical May & Baker Ltd
Publication of SE8204817D0 publication Critical patent/SE8204817D0/xx
Publication of SE8204817L publication Critical patent/SE8204817L/xx
Publication of SE448543B publication Critical patent/SE448543B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
SE8204817A 1981-08-24 1982-08-23 /3h/-imidazo/5,1-d/-1,2,3,5-tetrazin-4-onderivat, forfarande for deras framstellning och farmaceutiska kompositioner innehallande desamma SE448543B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8125791 1981-08-24

Publications (3)

Publication Number Publication Date
SE8204817D0 SE8204817D0 (sv) 1982-08-23
SE8204817L SE8204817L (sv) 1983-02-25
SE448543B true SE448543B (sv) 1987-03-02

Family

ID=10524141

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8204817A SE448543B (sv) 1981-08-24 1982-08-23 /3h/-imidazo/5,1-d/-1,2,3,5-tetrazin-4-onderivat, forfarande for deras framstellning och farmaceutiska kompositioner innehallande desamma

Country Status (29)

Country Link
JP (1) JPS5843975A (fi)
KR (1) KR890000094B1 (fi)
AT (1) AT380256B (fi)
AU (1) AU571430B2 (fi)
BE (1) BE894175A (fi)
CA (1) CA1197247A (fi)
CH (1) CH655114A5 (fi)
DE (2) DE19975037I2 (fi)
DK (1) DK161147C (fi)
ES (1) ES8400438A1 (fi)
FI (1) FI73434C (fi)
FR (1) FR2511679A1 (fi)
GB (1) GB2104522B (fi)
GE (1) GEP19960641B (fi)
GR (1) GR76863B (fi)
HU (1) HU186107B (fi)
IE (1) IE53408B1 (fi)
IL (1) IL66606A (fi)
IT (1) IT1152505B (fi)
LT (1) LT2436B (fi)
LU (1) LU84347A1 (fi)
LV (2) LV5511A3 (fi)
NL (2) NL192739C (fi)
NZ (1) NZ201668A (fi)
OA (1) OA07174A (fi)
SE (1) SE448543B (fi)
SU (1) SU1447284A3 (fi)
UA (1) UA5971A1 (fi)
ZA (1) ZA826120B (fi)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260291A (en) * 1981-08-24 1993-11-09 Cancer Research Campaign Technology Limited Tetrazine derivatives
FR2531958B1 (fr) * 1982-08-17 1986-10-31 May & Baker Ltd Nouveaux derive
GB2125402B (en) * 1982-08-17 1985-11-13 May & Baker Ltd New tetrazine derivatives
US4517182A (en) * 1983-05-24 1985-05-14 Warner-Lambert Company 3-(Haloethyl)-4-oxopyrazolo-[5,1-d]-1,2,3,5-tetrazine-8-carboxamide composition
GB8616125D0 (en) * 1986-07-02 1986-08-06 May & Baker Ltd Compositions of matter
AU622330B2 (en) * 1989-06-23 1992-04-02 Takeda Chemical Industries Ltd. Condensed heterocyclic compounds having a nitrogen atom in the bridgehead for use as fungicides
WO2005063757A2 (en) * 2003-12-30 2005-07-14 Chemagis Ltd. Novel crystalline forms of temozolomide
MX2007008781A (es) 2005-01-21 2007-09-11 Astex Therapeutics Ltd Compuestos farmaceuticos.
PE20080695A1 (es) 2006-04-27 2008-06-28 Banyu Pharma Co Ltd Derivados de dihidropirazolopirimidinona como inhibidores de quinasa weel
JP2008081492A (ja) 2006-08-31 2008-04-10 Banyu Pharmaceut Co Ltd オーロラａ選択的阻害作用を有する新規アミノピリジン誘導体
EP2073807A1 (en) 2006-10-12 2009-07-01 Astex Therapeutics Limited Pharmaceutical combinations
JP5528806B2 (ja) 2006-10-12 2014-06-25 アステックス、セラピューティックス、リミテッド 複合薬剤
JPWO2009054332A1 (ja) 2007-10-23 2011-03-03 萬有製薬株式会社 ピリドン置換ジヒドロピラゾロピリミジノン誘導体
PE20091101A1 (es) 2007-12-18 2009-07-26 Pharminox Ltd AMIDAS DE ACIDO 3-SUBSTITUIDO-4-OXO-3,4-DIHIDRO-IMIDAZO[5,1-d] [1,2,3,5-TETRACINA-8-CARBOXILICO Y SU EMPLEO
JP2012509868A (ja) * 2008-11-24 2012-04-26 リライアンス ライフ サイエンシズ ピーヴィーティー リミティッド テトラジン誘導体の製造方法
EP2403339B1 (en) 2009-03-06 2017-01-18 Merck Sharp & Dohme Corp. Combination cancer therapy with an akt inhibitor and other anticancer agents
PL2445915T3 (pl) 2009-06-23 2016-10-31 Związki 3-podstawionego-8-podstawionego-3H imidazo[5,1-d][1,2,3,5 tetrazyn]-4-onu i ich zastosowanie
RU2462466C1 (ru) * 2011-06-24 2012-09-27 Автономная Некоммерческая Организация "Научно-Исследовательский Центр Биотехнологии Антибиотиков И Других Биологически Активных Веществ "Биоан" Замещенные азоло[1,2,4,5]тетразины - ингибиторы актинобактериальных серин-треониновых протеинкиназ
US20140271657A1 (en) 2011-10-12 2014-09-18 Children's Medical Center Corporation Combinatorial compositions and methods of treating hemoglobinopathies
MX2018011102A (es) 2016-03-15 2019-01-10 Oryzon Genomics Sa Combinaciones de inhibidores de desmetilasa-1 especifica de lisina (lsd1) para uso en el tratamiento de tumores solidos.
KR101847342B1 (ko) * 2017-05-08 2018-04-11 (주)센텍코리아 웨어러블 체지방 연소량 측정기

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2932305A1 (de) * 1979-08-09 1981-02-26 Basf Ag Azolo- eckige klammer auf 5,1-d eckige klammer zu - eckige klammer auf 1,2,3,5 eckige klammer zu -tetrazin-4-one und verfahren zur herstellung dieser verbindungen

Also Published As

Publication number Publication date
NZ201668A (en) 1985-08-16
DE3231255A1 (de) 1983-03-03
KR840001175A (ko) 1984-03-28
NL192739C (nl) 1998-01-06
CA1197247A (fr) 1985-11-26
CH655114A5 (fr) 1986-03-27
AT380256B (de) 1986-05-12
FI73434C (fi) 1987-10-09
GR76863B (fi) 1984-09-04
AU8749382A (en) 1983-03-03
GEP19960641B (en) 1996-11-15
IL66606A0 (en) 1982-12-31
SU1447284A3 (ru) 1988-12-23
DE3231255C2 (fi) 1992-02-27
OA07174A (fr) 1984-04-30
IL66606A (en) 1987-07-31
ES515176A0 (es) 1983-11-01
DE19975037I2 (de) 2001-06-13
SE8204817D0 (sv) 1982-08-23
NL990010I2 (nl) 1999-09-01
LV5511A3 (lv) 1994-03-10
BE894175A (fr) 1983-02-23
LU84347A1 (fr) 1983-06-07
LT2436B (lt) 1994-02-15
IE822026L (en) 1983-02-24
DK377882A (da) 1983-02-25
GB2104522B (en) 1985-06-12
FI73434B (fi) 1987-06-30
DK161147B (da) 1991-06-03
HU186107B (en) 1985-06-28
IT8222938A0 (it) 1982-08-23
IT1152505B (it) 1987-01-07
JPS5843975A (ja) 1983-03-14
LV5621A3 (lv) 1994-05-10
FR2511679A1 (fr) 1983-02-25
FI822921L (fi) 1983-02-25
NL192739B (nl) 1997-09-01
ATA319182A (de) 1985-09-15
ZA826120B (en) 1983-07-27
NL990010I1 (nl) 1999-07-01
AU571430B2 (en) 1988-04-21
GB2104522A (en) 1983-03-09
IE53408B1 (en) 1988-11-09
NL8203286A (nl) 1983-03-16
DK161147C (da) 1991-11-18
FR2511679B1 (fi) 1985-02-01
SE8204817L (sv) 1983-02-25
KR890000094B1 (ko) 1989-03-07
ES8400438A1 (es) 1983-11-01
JPH045029B2 (fi) 1992-01-30
FI822921A0 (fi) 1982-08-23
UA5971A1 (uk) 1994-12-29

Similar Documents

Publication Publication Date Title
SE448543B (sv) /3h/-imidazo/5,1-d/-1,2,3,5-tetrazin-4-onderivat, forfarande for deras framstellning och farmaceutiska kompositioner innehallande desamma
US5260291A (en) Tetrazine derivatives
EP0150255B1 (en) Pyrrolo[1,2-a]imidazole and imidazo[1,2-a]pyridine immunomodulators
EP2970330A1 (en) Tetracyclic bromodomain inhibitors
EP0249043B1 (en) Quinolinecarboxylic acid derivatives
US5087625A (en) Pyridodiazepines and their use in the prevention or treatment of HIV infection
JPS6366182A (ja) テトラジン誘導体
CA1131631A (en) Quinazoline derivatives and pharmaceutical preparations
US3853880A (en) Pyrrolo (3,4-b) pyridine derivatives
EP0180158A1 (en) Thiadiazine compound, process for its preparation and pharmaceutical compositions containing it
EP0357172A2 (en) Benzofuro[3,2-c]Quinoline compounds
JPS60142987A (ja) セフアロスポリン誘導体
EP0682523A1 (de) Verwendung von trizyklischen isoindolinonen als antivirale arzneimittel und neue, optisch aktive isoindolinone
US4164579A (en) Hydroxythiazolidine-2-thiones
JPH07501047A (ja) ベンゾ［１，８］ナフチリジン誘導体および抗菌組成物
US3879390A (en) 2-pyridazinylisoindolin-1-one derivatives
JP3068175B2 (ja) イソチアゾロ〔５，４―ｂ〕ピリジン誘導体
EP0415303B1 (en) Pyrido [2,3-b][1,5]benzoxazepin (and thiazepin)-5(6H)-ones and -thiones and their use in the prevention or treatment of HIV infection
EP0487097B1 (en) Pyrazoloacridone derivatives
EP0573659B1 (en) Pyrazolothiazolopyrimidine derivative
JPS63500031A (ja) オキソジアジン化合物
US4853385A (en) 7-N,8-N-Ethylenemitomycin 8-imines
JPH0441151B2 (fi)
HU189321B (en) Process for producing new condensed tetrazine derivatives
JPH0417191B2 (fi)

Legal Events

Date Code Title Description
NAL Patent in force

Ref document number: 8204817-4

Format of ref document f/p: F

SPCF Application for supplementary protection certificate filed

Free format text: 9990019, 990126

SPCG Supplementary protection certificate granted

Free format text: 9990019, 990126, EXPIRES: 20070823

NUG Patent has lapsed

Ref document number: 8204817-4

Format of ref document f/p: F