ES515176A0 - Procedimiento para preparar derivados de (3h)-imidazo(5,1-d)-1,2,3,5-tetrazin-4-ona. - Google Patents

Procedimiento para preparar derivados de (3h)-imidazo(5,1-d)-1,2,3,5-tetrazin-4-ona.

Info

Publication number
ES515176A0
ES515176A0 ES515176A ES515176A ES515176A0 ES 515176 A0 ES515176 A0 ES 515176A0 ES 515176 A ES515176 A ES 515176A ES 515176 A ES515176 A ES 515176A ES 515176 A0 ES515176 A0 ES 515176A0
Authority
ES
Spain
Prior art keywords
tetrazin
ona
imidazo
procedure
preparing derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES515176A
Other languages
English (en)
Spanish (es)
Other versions
ES8400438A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
May and Baker Ltd
Original Assignee
May and Baker Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by May and Baker Ltd filed Critical May and Baker Ltd
Publication of ES515176A0 publication Critical patent/ES515176A0/es
Publication of ES8400438A1 publication Critical patent/ES8400438A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
ES515176A 1981-08-24 1982-08-23 Procedimiento para preparar derivados de (3h)-imidazo(5,1-d)-1,2,3,5-tetrazin-4-ona. Expired ES8400438A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8125791 1981-08-24

Publications (2)

Publication Number Publication Date
ES515176A0 true ES515176A0 (es) 1983-11-01
ES8400438A1 ES8400438A1 (es) 1983-11-01

Family

ID=10524141

Family Applications (1)

Application Number Title Priority Date Filing Date
ES515176A Expired ES8400438A1 (es) 1981-08-24 1982-08-23 Procedimiento para preparar derivados de (3h)-imidazo(5,1-d)-1,2,3,5-tetrazin-4-ona.

Country Status (29)

Country Link
JP (1) JPS5843975A (ja)
KR (1) KR890000094B1 (ja)
AT (1) AT380256B (ja)
AU (1) AU571430B2 (ja)
BE (1) BE894175A (ja)
CA (1) CA1197247A (ja)
CH (1) CH655114A5 (ja)
DE (2) DE19975037I2 (ja)
DK (1) DK161147C (ja)
ES (1) ES8400438A1 (ja)
FI (1) FI73434C (ja)
FR (1) FR2511679A1 (ja)
GB (1) GB2104522B (ja)
GE (1) GEP19960641B (ja)
GR (1) GR76863B (ja)
HU (1) HU186107B (ja)
IE (1) IE53408B1 (ja)
IL (1) IL66606A (ja)
IT (1) IT1152505B (ja)
LT (1) LT2436B (ja)
LU (1) LU84347A1 (ja)
LV (2) LV5511A3 (ja)
NL (2) NL192739C (ja)
NZ (1) NZ201668A (ja)
OA (1) OA07174A (ja)
SE (1) SE448543B (ja)
SU (1) SU1447284A3 (ja)
UA (1) UA5971A1 (ja)
ZA (1) ZA826120B (ja)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260291A (en) * 1981-08-24 1993-11-09 Cancer Research Campaign Technology Limited Tetrazine derivatives
FR2531958B1 (fr) * 1982-08-17 1986-10-31 May & Baker Ltd Nouveaux derive
GB2125402B (en) * 1982-08-17 1985-11-13 May & Baker Ltd New tetrazine derivatives
US4517182A (en) * 1983-05-24 1985-05-14 Warner-Lambert Company 3-(Haloethyl)-4-oxopyrazolo-[5,1-d]-1,2,3,5-tetrazine-8-carboxamide composition
GB8616125D0 (en) * 1986-07-02 1986-08-06 May & Baker Ltd Compositions of matter
AU622330B2 (en) * 1989-06-23 1992-04-02 Takeda Chemical Industries Ltd. Condensed heterocyclic compounds having a nitrogen atom in the bridgehead for use as fungicides
WO2005063757A2 (en) * 2003-12-30 2005-07-14 Chemagis Ltd. Novel crystalline forms of temozolomide
MX2007008781A (es) 2005-01-21 2007-09-11 Astex Therapeutics Ltd Compuestos farmaceuticos.
PE20080695A1 (es) 2006-04-27 2008-06-28 Banyu Pharma Co Ltd Derivados de dihidropirazolopirimidinona como inhibidores de quinasa weel
JP2008081492A (ja) 2006-08-31 2008-04-10 Banyu Pharmaceut Co Ltd オーロラａ選択的阻害作用を有する新規アミノピリジン誘導体
EP2073807A1 (en) 2006-10-12 2009-07-01 Astex Therapeutics Limited Pharmaceutical combinations
JP5528806B2 (ja) 2006-10-12 2014-06-25 アステックス、セラピューティックス、リミテッド 複合薬剤
JPWO2009054332A1 (ja) 2007-10-23 2011-03-03 萬有製薬株式会社 ピリドン置換ジヒドロピラゾロピリミジノン誘導体
PE20091101A1 (es) 2007-12-18 2009-07-26 Pharminox Ltd AMIDAS DE ACIDO 3-SUBSTITUIDO-4-OXO-3,4-DIHIDRO-IMIDAZO[5,1-d] [1,2,3,5-TETRACINA-8-CARBOXILICO Y SU EMPLEO
JP2012509868A (ja) * 2008-11-24 2012-04-26 リライアンス ライフ サイエンシズ ピーヴィーティー リミティッド テトラジン誘導体の製造方法
EP2403339B1 (en) 2009-03-06 2017-01-18 Merck Sharp & Dohme Corp. Combination cancer therapy with an akt inhibitor and other anticancer agents
PL2445915T3 (pl) 2009-06-23 2016-10-31 Związki 3-podstawionego-8-podstawionego-3H imidazo[5,1-d][1,2,3,5 tetrazyn]-4-onu i ich zastosowanie
RU2462466C1 (ru) * 2011-06-24 2012-09-27 Автономная Некоммерческая Организация "Научно-Исследовательский Центр Биотехнологии Антибиотиков И Других Биологически Активных Веществ "Биоан" Замещенные азоло[1,2,4,5]тетразины - ингибиторы актинобактериальных серин-треониновых протеинкиназ
US20140271657A1 (en) 2011-10-12 2014-09-18 Children's Medical Center Corporation Combinatorial compositions and methods of treating hemoglobinopathies
MX2018011102A (es) 2016-03-15 2019-01-10 Oryzon Genomics Sa Combinaciones de inhibidores de desmetilasa-1 especifica de lisina (lsd1) para uso en el tratamiento de tumores solidos.
KR101847342B1 (ko) * 2017-05-08 2018-04-11 (주)센텍코리아 웨어러블 체지방 연소량 측정기

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2932305A1 (de) * 1979-08-09 1981-02-26 Basf Ag Azolo- eckige klammer auf 5,1-d eckige klammer zu - eckige klammer auf 1,2,3,5 eckige klammer zu -tetrazin-4-one und verfahren zur herstellung dieser verbindungen

Also Published As

Publication number Publication date
NZ201668A (en) 1985-08-16
DE3231255A1 (de) 1983-03-03
KR840001175A (ko) 1984-03-28
NL192739C (nl) 1998-01-06
CA1197247A (fr) 1985-11-26
CH655114A5 (fr) 1986-03-27
AT380256B (de) 1986-05-12
FI73434C (fi) 1987-10-09
GR76863B (ja) 1984-09-04
AU8749382A (en) 1983-03-03
GEP19960641B (en) 1996-11-15
IL66606A0 (en) 1982-12-31
SU1447284A3 (ru) 1988-12-23
DE3231255C2 (ja) 1992-02-27
OA07174A (fr) 1984-04-30
IL66606A (en) 1987-07-31
DE19975037I2 (de) 2001-06-13
SE8204817D0 (sv) 1982-08-23
NL990010I2 (nl) 1999-09-01
LV5511A3 (lv) 1994-03-10
BE894175A (fr) 1983-02-23
LU84347A1 (fr) 1983-06-07
LT2436B (lt) 1994-02-15
IE822026L (en) 1983-02-24
DK377882A (da) 1983-02-25
GB2104522B (en) 1985-06-12
FI73434B (fi) 1987-06-30
DK161147B (da) 1991-06-03
SE448543B (sv) 1987-03-02
HU186107B (en) 1985-06-28
IT8222938A0 (it) 1982-08-23
IT1152505B (it) 1987-01-07
JPS5843975A (ja) 1983-03-14
LV5621A3 (lv) 1994-05-10
FR2511679A1 (fr) 1983-02-25
FI822921L (fi) 1983-02-25
NL192739B (nl) 1997-09-01
ATA319182A (de) 1985-09-15
ZA826120B (en) 1983-07-27
NL990010I1 (nl) 1999-07-01
AU571430B2 (en) 1988-04-21
GB2104522A (en) 1983-03-09
IE53408B1 (en) 1988-11-09
NL8203286A (nl) 1983-03-16
DK161147C (da) 1991-11-18
FR2511679B1 (ja) 1985-02-01
SE8204817L (sv) 1983-02-25
KR890000094B1 (ko) 1989-03-07
ES8400438A1 (es) 1983-11-01
JPH045029B2 (ja) 1992-01-30
FI822921A0 (fi) 1982-08-23
UA5971A1 (uk) 1994-12-29

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Legal Events

Date Code Title Description
SPCF Request for supplementary protection certificate filed

Free format text: TEMOZOLOMIDE (TEMODAL)

Spc suppl protection certif: C9900027

Filing date: 19990726

SPCG Supplementary protection certificate granted

Free format text: TEMOZOLOMIDE (TEMODAL)

Spc suppl protection certif: C9900027

Filing date: 19990726

Expiry date: 20080719

Effective date: 20020610