ES515176A0 - PROCEDURE FOR PREPARING DERIVATIVES OF (3H) -IMIDAZO (5,1-D) -1,2,3,5-TETRAZIN-4-ONA. - Google Patents

PROCEDURE FOR PREPARING DERIVATIVES OF (3H) -IMIDAZO (5,1-D) -1,2,3,5-TETRAZIN-4-ONA.

Info

Publication number
ES515176A0
ES515176A0 ES515176A ES515176A ES515176A0 ES 515176 A0 ES515176 A0 ES 515176A0 ES 515176 A ES515176 A ES 515176A ES 515176 A ES515176 A ES 515176A ES 515176 A0 ES515176 A0 ES 515176A0
Authority
ES
Spain
Prior art keywords
tetrazin
ona
imidazo
procedure
preparing derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES515176A
Other languages
Spanish (es)
Other versions
ES8400438A1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
May and Baker Ltd
Original Assignee
May and Baker Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by May and Baker Ltd filed Critical May and Baker Ltd
Publication of ES515176A0 publication Critical patent/ES515176A0/en
Publication of ES8400438A1 publication Critical patent/ES8400438A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
ES515176A 1981-08-24 1982-08-23 Tetrazine derivative Expired ES8400438A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8125791 1981-08-24

Publications (2)

Publication Number Publication Date
ES515176A0 true ES515176A0 (en) 1983-11-01
ES8400438A1 ES8400438A1 (en) 1983-11-01

Family

ID=10524141

Family Applications (1)

Application Number Title Priority Date Filing Date
ES515176A Expired ES8400438A1 (en) 1981-08-24 1982-08-23 Tetrazine derivative

Country Status (29)

Country Link
JP (1) JPS5843975A (en)
KR (1) KR890000094B1 (en)
AT (1) AT380256B (en)
AU (1) AU571430B2 (en)
BE (1) BE894175A (en)
CA (1) CA1197247A (en)
CH (1) CH655114A5 (en)
DE (2) DE3231255A1 (en)
DK (1) DK161147C (en)
ES (1) ES8400438A1 (en)
FI (1) FI73434C (en)
FR (1) FR2511679A1 (en)
GB (1) GB2104522B (en)
GE (1) GEP19960641B (en)
GR (1) GR76863B (en)
HU (1) HU186107B (en)
IE (1) IE53408B1 (en)
IL (1) IL66606A (en)
IT (1) IT1152505B (en)
LT (1) LT2436B (en)
LU (1) LU84347A1 (en)
LV (2) LV5511A3 (en)
NL (2) NL192739C (en)
NZ (1) NZ201668A (en)
OA (1) OA07174A (en)
SE (1) SE448543B (en)
SU (1) SU1447284A3 (en)
UA (1) UA5971A1 (en)
ZA (1) ZA826120B (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260291A (en) * 1981-08-24 1993-11-09 Cancer Research Campaign Technology Limited Tetrazine derivatives
GB2125402B (en) * 1982-08-17 1985-11-13 May & Baker Ltd New tetrazine derivatives
FR2531958B1 (en) * 1982-08-17 1986-10-31 May & Baker Ltd NEW DERIVATIVES
US4517182A (en) * 1983-05-24 1985-05-14 Warner-Lambert Company 3-(Haloethyl)-4-oxopyrazolo-[5,1-d]-1,2,3,5-tetrazine-8-carboxamide composition
GB8616125D0 (en) * 1986-07-02 1986-08-06 May & Baker Ltd Compositions of matter
AU622330B2 (en) * 1989-06-23 1992-04-02 Takeda Chemical Industries Ltd. Condensed heterocyclic compounds having a nitrogen atom in the bridgehead for use as fungicides
BRPI0417117A (en) * 2003-12-30 2007-03-06 Chemagis Ltd crystallized temozolomide, crystallized temozolomide preparation process, pharmaceutical composition, method of producing medicament containing temozolomide and method of treating a medical condition for which thermozolomide is beneficial
US20090036435A1 (en) 2005-01-21 2009-02-05 Astex Therapeutics Limited Pharmaceutical Compounds
AR060635A1 (en) 2006-04-27 2008-07-02 Banyu Pharma Co Ltd DERIVATIVES OF 1,2-DIHIDRO-3H-PIRAZOLO [3,4-D] PIRIMIDIN-3-ONA, PHARMACEUTICAL COMPOSITIONS THAT INCLUDE THEM AND THEIR USE IN THE TREATMENT OF CANCER
JP2008081492A (en) 2006-08-31 2008-04-10 Banyu Pharmaceut Co Ltd New aminopyridine derivative having aurora a selective inhibitory action
US8916552B2 (en) 2006-10-12 2014-12-23 Astex Therapeutics Limited Pharmaceutical combinations
EP2073807A1 (en) 2006-10-12 2009-07-01 Astex Therapeutics Limited Pharmaceutical combinations
CA2703489A1 (en) 2007-10-23 2009-04-30 Banyu Pharmaceutical Co., Ltd. Pyridone-substituted-dihydropyrazolopyrimidinone derivative
PE20091101A1 (en) * 2007-12-18 2009-07-26 Pharminox Ltd 3-SUBSTITUTED-4-OXO-3,4-DIHYDRO-IMIDAZO [5,1-d] [1,2,3,5-TETRACINE-8-CARBOXYL ACID AMIDES AND ITS USE
CA2744560A1 (en) * 2008-11-24 2010-05-27 Reliance Life Sciences Pvt. Ltd. Process for the preparation of tetrazine derivatives
EP2403339B1 (en) 2009-03-06 2017-01-18 Merck Sharp & Dohme Corp. Combination cancer therapy with an akt inhibitor and other anticancer agents
EP2445915B1 (en) 2009-06-23 2016-04-20 Pharminox Limited 3-substituted-8-substituted-3h imidazo[5,1-d][1,2,3,5-tetrazin-4-one compounds and their use
RU2462466C1 (en) * 2011-06-24 2012-09-27 Автономная Некоммерческая Организация "Научно-Исследовательский Центр Биотехнологии Антибиотиков И Других Биологически Активных Веществ "Биоан" Substituted azolo[1,2,4,5]tetrazines - inhibitors of antibacterial serine-threonine protein kinases
US20140271657A1 (en) 2011-10-12 2014-09-18 Children's Medical Center Corporation Combinatorial compositions and methods of treating hemoglobinopathies
CN109195593A (en) 2016-03-15 2019-01-11 奥莱松基因组股份有限公司 For treating the combination of the LSD1 inhibitor of solid tumor
KR101847342B1 (en) * 2017-05-08 2018-04-11 (주)센텍코리아 Wearable body fat burning measurement device

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2932305A1 (en) * 1979-08-09 1981-02-26 Basf Ag Pyrrolo-, pyrazolo-, imidazo- and thiazolo-tetrazin-4-one derivs. - prepd. from amino-azole cpds. by diazotisation and reaction with isocyanate

Also Published As

Publication number Publication date
GR76863B (en) 1984-09-04
FR2511679B1 (en) 1985-02-01
SU1447284A3 (en) 1988-12-23
DE19975037I2 (en) 2001-06-13
FR2511679A1 (en) 1983-02-25
IL66606A (en) 1987-07-31
NZ201668A (en) 1985-08-16
JPS5843975A (en) 1983-03-14
CA1197247A (en) 1985-11-26
KR890000094B1 (en) 1989-03-07
DK377882A (en) 1983-02-25
BE894175A (en) 1983-02-23
DE3231255A1 (en) 1983-03-03
IE822026L (en) 1983-02-24
SE448543B (en) 1987-03-02
NL192739C (en) 1998-01-06
FI822921A0 (en) 1982-08-23
DK161147C (en) 1991-11-18
CH655114A5 (en) 1986-03-27
NL8203286A (en) 1983-03-16
ZA826120B (en) 1983-07-27
IT1152505B (en) 1987-01-07
NL192739B (en) 1997-09-01
OA07174A (en) 1984-04-30
AU8749382A (en) 1983-03-03
DK161147B (en) 1991-06-03
KR840001175A (en) 1984-03-28
SE8204817D0 (en) 1982-08-23
LV5511A3 (en) 1994-03-10
FI73434B (en) 1987-06-30
GB2104522A (en) 1983-03-09
FI73434C (en) 1987-10-09
ES8400438A1 (en) 1983-11-01
AT380256B (en) 1986-05-12
GEP19960641B (en) 1996-11-15
UA5971A1 (en) 1994-12-29
HU186107B (en) 1985-06-28
LU84347A1 (en) 1983-06-07
IL66606A0 (en) 1982-12-31
SE8204817L (en) 1983-02-25
DE3231255C2 (en) 1992-02-27
LV5621A3 (en) 1994-05-10
NL990010I1 (en) 1999-07-01
JPH045029B2 (en) 1992-01-30
IT8222938A0 (en) 1982-08-23
LT2436B (en) 1994-02-15
ATA319182A (en) 1985-09-15
IE53408B1 (en) 1988-11-09
FI822921L (en) 1983-02-25
GB2104522B (en) 1985-06-12
NL990010I2 (en) 1999-09-01
AU571430B2 (en) 1988-04-21

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ES515176A0 (en) PROCEDURE FOR PREPARING DERIVATIVES OF (3H) -IMIDAZO (5,1-D) -1,2,3,5-TETRAZIN-4-ONA.
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Legal Events

Date Code Title Description
SPCF Request for supplementary protection certificate filed

Free format text: TEMOZOLOMIDE (TEMODAL)

Spc suppl protection certif: C9900027

Filing date: 19990726

SPCG Supplementary protection certificate granted

Free format text: TEMOZOLOMIDE (TEMODAL)

Spc suppl protection certif: C9900027

Filing date: 19990726

Expiry date: 20080719

Effective date: 20020610