NL990010I1 - Ä3HÜ-imidazo-Ä5,1-dÜ-1,2,3,5-tetrazine-4-one derivatives and pharmaceutical compositions containing these derivatives. - Google Patents

Ä3HÜ-imidazo-Ä5,1-dÜ-1,2,3,5-tetrazine-4-one derivatives and pharmaceutical compositions containing these derivatives.

Info

Publication number
NL990010I1
NL990010I1 NL990010C NL990010C NL990010I1 NL 990010 I1 NL990010 I1 NL 990010I1 NL 990010 C NL990010 C NL 990010C NL 990010 C NL990010 C NL 990010C NL 990010 I1 NL990010 I1 NL 990010I1
Authority
NL
Netherlands
Prior art keywords
derivatives
ä3hü
tetrazine
imidazo
pharmaceutical compositions
Prior art date
Application number
NL990010C
Other languages
Dutch (nl)
Other versions
NL990010I2 (en
Original Assignee
Cancer Res Campaign Tech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cancer Res Campaign Tech filed Critical Cancer Res Campaign Tech
Publication of NL990010I1 publication Critical patent/NL990010I1/en
Publication of NL990010I2 publication Critical patent/NL990010I2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
NL990010C 1981-08-24 1999-04-01 Ä3HÜ-imidazo-Ä5,1-dÜ-1,2,3,5-tetrazine-4-one derivatives and pharmaceutical compositions containing these derivatives. NL990010I2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8125791 1981-08-24

Publications (2)

Publication Number Publication Date
NL990010I1 true NL990010I1 (en) 1999-07-01
NL990010I2 NL990010I2 (en) 1999-09-01

Family

ID=10524141

Family Applications (2)

Application Number Title Priority Date Filing Date
NL8203286A NL192739C (en) 1981-08-24 1982-08-23 3H-imidazo-5,1-d-1,2,3,5-tetrazine-4-one derivatives and pharmaceutical compositions containing these derivatives.
NL990010C NL990010I2 (en) 1981-08-24 1999-04-01 Ä3HÜ-imidazo-Ä5,1-dÜ-1,2,3,5-tetrazine-4-one derivatives and pharmaceutical compositions containing these derivatives.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NL8203286A NL192739C (en) 1981-08-24 1982-08-23 3H-imidazo-5,1-d-1,2,3,5-tetrazine-4-one derivatives and pharmaceutical compositions containing these derivatives.

Country Status (29)

Country Link
JP (1) JPS5843975A (en)
KR (1) KR890000094B1 (en)
AT (1) AT380256B (en)
AU (1) AU571430B2 (en)
BE (1) BE894175A (en)
CA (1) CA1197247A (en)
CH (1) CH655114A5 (en)
DE (2) DE19975037I2 (en)
DK (1) DK161147C (en)
ES (1) ES8400438A1 (en)
FI (1) FI73434C (en)
FR (1) FR2511679A1 (en)
GB (1) GB2104522B (en)
GE (1) GEP19960641B (en)
GR (1) GR76863B (en)
HU (1) HU186107B (en)
IE (1) IE53408B1 (en)
IL (1) IL66606A (en)
IT (1) IT1152505B (en)
LT (1) LT2436B (en)
LU (1) LU84347A1 (en)
LV (2) LV5511A3 (en)
NL (2) NL192739C (en)
NZ (1) NZ201668A (en)
OA (1) OA07174A (en)
SE (1) SE448543B (en)
SU (1) SU1447284A3 (en)
UA (1) UA5971A1 (en)
ZA (1) ZA826120B (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260291A (en) * 1981-08-24 1993-11-09 Cancer Research Campaign Technology Limited Tetrazine derivatives
GB2125402B (en) * 1982-08-17 1985-11-13 May & Baker Ltd New tetrazine derivatives
FR2531958B1 (en) * 1982-08-17 1986-10-31 May & Baker Ltd NEW DERIVATIVES
US4517182A (en) * 1983-05-24 1985-05-14 Warner-Lambert Company 3-(Haloethyl)-4-oxopyrazolo-[5,1-d]-1,2,3,5-tetrazine-8-carboxamide composition
GB8616125D0 (en) * 1986-07-02 1986-08-06 May & Baker Ltd Compositions of matter
AU622330B2 (en) * 1989-06-23 1992-04-02 Takeda Chemical Industries Ltd. Condensed heterocyclic compounds having a nitrogen atom in the bridgehead for use as fungicides
EP1706407A2 (en) 2003-12-30 2006-10-04 Chemagis Ltd. Novel crystalline forms of temozolomide
EP1845973B1 (en) 2005-01-21 2015-08-12 Astex Therapeutics Limited Pharmaceutical compounds
PE20080695A1 (en) 2006-04-27 2008-06-28 Banyu Pharma Co Ltd DIHYDROPIRAZOLOPYRIMIDINONE DERIVATIVES AS KINASE WEEL INHIBITORS
JP2008081492A (en) 2006-08-31 2008-04-10 Banyu Pharmaceut Co Ltd New aminopyridine derivative having aurora a selective inhibitory action
WO2008044045A1 (en) 2006-10-12 2008-04-17 Astex Therapeutics Limited Pharmaceutical combinations
US8916552B2 (en) 2006-10-12 2014-12-23 Astex Therapeutics Limited Pharmaceutical combinations
WO2009054332A1 (en) 2007-10-23 2009-04-30 Banyu Pharmaceutical Co., Ltd. Pyridone-substituted-dihydropyrazolopyrimidinone derivative
PE20091101A1 (en) * 2007-12-18 2009-07-26 Pharminox Ltd 3-SUBSTITUTED-4-OXO-3,4-DIHYDRO-IMIDAZO [5,1-d] [1,2,3,5-TETRACINE-8-CARBOXYL ACID AMIDES AND ITS USE
AU2009318790A1 (en) * 2008-11-24 2011-06-23 Reliance Life Sciences Pvt. Ltd. Process for the preparation of tetrazine derivatives
US8481503B2 (en) 2009-03-06 2013-07-09 Merck Sharp & Dohme Corp. Combination cancer therapy with an AKT inhibitor and other anticancer agents
PL2445915T3 (en) 2009-06-23 2016-10-31 3-substituted-8-substituted-3h imidazo[5,1-d][1,2,3,5-tetrazin-4-one compounds and their use
RU2462466C1 (en) * 2011-06-24 2012-09-27 Автономная Некоммерческая Организация "Научно-Исследовательский Центр Биотехнологии Антибиотиков И Других Биологически Активных Веществ "Биоан" Substituted azolo[1,2,4,5]tetrazines - inhibitors of antibacterial serine-threonine protein kinases
WO2013055985A1 (en) 2011-10-12 2013-04-18 Children's Medical Center Corporation Combinatorial compositions and methods of treating hemoglobinopathies
KR20230042756A (en) 2016-03-15 2023-03-29 오리존 지노믹스 에스.에이. Combinations of lsd1 inhibitors for use in the treatment of solid tumors
KR101847342B1 (en) * 2017-05-08 2018-04-11 (주)센텍코리아 Wearable body fat burning measurement device

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2932305A1 (en) * 1979-08-09 1981-02-26 Basf Ag Pyrrolo-, pyrazolo-, imidazo- and thiazolo-tetrazin-4-one derivs. - prepd. from amino-azole cpds. by diazotisation and reaction with isocyanate

Also Published As

Publication number Publication date
ES515176A0 (en) 1983-11-01
JPH045029B2 (en) 1992-01-30
ATA319182A (en) 1985-09-15
NL8203286A (en) 1983-03-16
DE3231255C2 (en) 1992-02-27
CA1197247A (en) 1985-11-26
NZ201668A (en) 1985-08-16
FI822921A0 (en) 1982-08-23
DE19975037I2 (en) 2001-06-13
UA5971A1 (en) 1994-12-29
SE8204817L (en) 1983-02-25
AT380256B (en) 1986-05-12
GR76863B (en) 1984-09-04
IE822026L (en) 1983-02-24
GB2104522B (en) 1985-06-12
LV5511A3 (en) 1994-03-10
ZA826120B (en) 1983-07-27
IT8222938A0 (en) 1982-08-23
GB2104522A (en) 1983-03-09
IE53408B1 (en) 1988-11-09
FI73434C (en) 1987-10-09
CH655114A5 (en) 1986-03-27
JPS5843975A (en) 1983-03-14
AU571430B2 (en) 1988-04-21
OA07174A (en) 1984-04-30
HU186107B (en) 1985-06-28
KR840001175A (en) 1984-03-28
DK161147C (en) 1991-11-18
DE3231255A1 (en) 1983-03-03
NL192739C (en) 1998-01-06
FI73434B (en) 1987-06-30
SU1447284A3 (en) 1988-12-23
LU84347A1 (en) 1983-06-07
SE8204817D0 (en) 1982-08-23
IT1152505B (en) 1987-01-07
DK161147B (en) 1991-06-03
NL990010I2 (en) 1999-09-01
LT2436B (en) 1994-02-15
FI822921L (en) 1983-02-25
FR2511679A1 (en) 1983-02-25
IL66606A (en) 1987-07-31
GEP19960641B (en) 1996-11-15
KR890000094B1 (en) 1989-03-07
IL66606A0 (en) 1982-12-31
NL192739B (en) 1997-09-01
DK377882A (en) 1983-02-25
AU8749382A (en) 1983-03-03
ES8400438A1 (en) 1983-11-01
BE894175A (en) 1983-02-23
LV5621A3 (en) 1994-05-10
FR2511679B1 (en) 1985-02-01
SE448543B (en) 1987-03-02

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