NL192739B - 3H-imidazo-5,1-d-1,2,3,5-tetrazine-4-one derivatives and pharmaceutical compositions containing these derivatives. - Google Patents

3H-imidazo-5,1-d-1,2,3,5-tetrazine-4-one derivatives and pharmaceutical compositions containing these derivatives.

Info

Publication number
NL192739B
NL192739B NL8203286A NL8203286A NL192739B NL 192739 B NL192739 B NL 192739B NL 8203286 A NL8203286 A NL 8203286A NL 8203286 A NL8203286 A NL 8203286A NL 192739 B NL192739 B NL 192739B
Authority
NL
Netherlands
Prior art keywords
derivatives
tetrazine
imidazo
pharmaceutical compositions
compositions containing
Prior art date
Application number
NL8203286A
Other languages
Dutch (nl)
Other versions
NL192739C (en
NL8203286A (en
Original Assignee
Cancer Res Campaign Tech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cancer Res Campaign Tech filed Critical Cancer Res Campaign Tech
Publication of NL8203286A publication Critical patent/NL8203286A/en
Publication of NL192739B publication Critical patent/NL192739B/en
Application granted granted Critical
Publication of NL192739C publication Critical patent/NL192739C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
NL8203286A 1981-08-24 1982-08-23 3H-imidazo-5,1-d-1,2,3,5-tetrazine-4-one derivatives and pharmaceutical compositions containing these derivatives. NL192739C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8125791 1981-08-24
GB8125791 1981-08-24

Publications (3)

Publication Number Publication Date
NL8203286A NL8203286A (en) 1983-03-16
NL192739B true NL192739B (en) 1997-09-01
NL192739C NL192739C (en) 1998-01-06

Family

ID=10524141

Family Applications (2)

Application Number Title Priority Date Filing Date
NL8203286A NL192739C (en) 1981-08-24 1982-08-23 3H-imidazo-5,1-d-1,2,3,5-tetrazine-4-one derivatives and pharmaceutical compositions containing these derivatives.
NL990010C NL990010I2 (en) 1981-08-24 1999-04-01 Ä3HÜ-imidazo-Ä5,1-dÜ-1,2,3,5-tetrazine-4-one derivatives and pharmaceutical compositions containing these derivatives.

Family Applications After (1)

Application Number Title Priority Date Filing Date
NL990010C NL990010I2 (en) 1981-08-24 1999-04-01 Ä3HÜ-imidazo-Ä5,1-dÜ-1,2,3,5-tetrazine-4-one derivatives and pharmaceutical compositions containing these derivatives.

Country Status (29)

Country Link
JP (1) JPS5843975A (en)
KR (1) KR890000094B1 (en)
AT (1) AT380256B (en)
AU (1) AU571430B2 (en)
BE (1) BE894175A (en)
CA (1) CA1197247A (en)
CH (1) CH655114A5 (en)
DE (2) DE19975037I2 (en)
DK (1) DK161147C (en)
ES (1) ES8400438A1 (en)
FI (1) FI73434C (en)
FR (1) FR2511679A1 (en)
GB (1) GB2104522B (en)
GE (1) GEP19960641B (en)
GR (1) GR76863B (en)
HU (1) HU186107B (en)
IE (1) IE53408B1 (en)
IL (1) IL66606A (en)
IT (1) IT1152505B (en)
LT (1) LT2436B (en)
LU (1) LU84347A1 (en)
LV (2) LV5511A3 (en)
NL (2) NL192739C (en)
NZ (1) NZ201668A (en)
OA (1) OA07174A (en)
SE (1) SE448543B (en)
SU (1) SU1447284A3 (en)
UA (1) UA5971A1 (en)
ZA (1) ZA826120B (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260291A (en) * 1981-08-24 1993-11-09 Cancer Research Campaign Technology Limited Tetrazine derivatives
FR2531958B1 (en) * 1982-08-17 1986-10-31 May & Baker Ltd NEW DERIVATIVES
GB2125402B (en) * 1982-08-17 1985-11-13 May & Baker Ltd New tetrazine derivatives
US4517182A (en) * 1983-05-24 1985-05-14 Warner-Lambert Company 3-(Haloethyl)-4-oxopyrazolo-[5,1-d]-1,2,3,5-tetrazine-8-carboxamide composition
GB8616125D0 (en) * 1986-07-02 1986-08-06 May & Baker Ltd Compositions of matter
AU622330B2 (en) * 1989-06-23 1992-04-02 Takeda Chemical Industries Ltd. Condensed heterocyclic compounds having a nitrogen atom in the bridgehead for use as fungicides
EP1706407A2 (en) * 2003-12-30 2006-10-04 Chemagis Ltd. Novel crystalline forms of temozolomide
ES2552338T3 (en) 2005-01-21 2015-11-27 Astex Therapeutics Limited Pharmaceutical compounds
AR060635A1 (en) 2006-04-27 2008-07-02 Banyu Pharma Co Ltd DERIVATIVES OF 1,2-DIHIDRO-3H-PIRAZOLO [3,4-D] PIRIMIDIN-3-ONA, PHARMACEUTICAL COMPOSITIONS THAT INCLUDE THEM AND THEIR USE IN THE TREATMENT OF CANCER
JP2008081492A (en) 2006-08-31 2008-04-10 Banyu Pharmaceut Co Ltd New aminopyridine derivative having aurora a selective inhibitory action
EP2073807A1 (en) 2006-10-12 2009-07-01 Astex Therapeutics Limited Pharmaceutical combinations
US8916552B2 (en) 2006-10-12 2014-12-23 Astex Therapeutics Limited Pharmaceutical combinations
AU2008315048A1 (en) 2007-10-23 2009-04-30 Msd K.K. Pyridone-substituted-dihydropyrazolopyrimidinone derivative
PE20091101A1 (en) 2007-12-18 2009-07-26 Pharminox Ltd 3-SUBSTITUTED-4-OXO-3,4-DIHYDRO-IMIDAZO [5,1-d] [1,2,3,5-TETRACINE-8-CARBOXYL ACID AMIDES AND ITS USE
EP2367828B1 (en) * 2008-11-24 2014-06-11 Reliance Life Sciences Pvt., Ltd. Process for the preparation of tetrazine derivatives
EP2403339B1 (en) 2009-03-06 2017-01-18 Merck Sharp & Dohme Corp. Combination cancer therapy with an akt inhibitor and other anticancer agents
JP2012530775A (en) 2009-06-23 2012-12-06 ファーミノックス リミテッド 3-substituted-8-substituted-3H-imidazo [5,1-d] [1,2,3,5-tetrazin-4-one compounds and uses thereof
RU2462466C1 (en) * 2011-06-24 2012-09-27 Автономная Некоммерческая Организация "Научно-Исследовательский Центр Биотехнологии Антибиотиков И Других Биологически Активных Веществ "Биоан" Substituted azolo[1,2,4,5]tetrazines - inhibitors of antibacterial serine-threonine protein kinases
US20140271657A1 (en) 2011-10-12 2014-09-18 Children's Medical Center Corporation Combinatorial compositions and methods of treating hemoglobinopathies
EA201892075A1 (en) 2016-03-15 2019-04-30 Оризон Дженомикс, С.А. COMBINATION OF LSD1 INHIBITORS FOR USE FOR THE TREATMENT OF SOLID TUMORS
KR101847342B1 (en) * 2017-05-08 2018-04-11 (주)센텍코리아 Wearable body fat burning measurement device

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2932305A1 (en) * 1979-08-09 1981-02-26 Basf Ag Pyrrolo-, pyrazolo-, imidazo- and thiazolo-tetrazin-4-one derivs. - prepd. from amino-azole cpds. by diazotisation and reaction with isocyanate

Also Published As

Publication number Publication date
KR890000094B1 (en) 1989-03-07
DE19975037I2 (en) 2001-06-13
FI822921L (en) 1983-02-25
DK161147C (en) 1991-11-18
ES515176A0 (en) 1983-11-01
FI73434B (en) 1987-06-30
OA07174A (en) 1984-04-30
FR2511679A1 (en) 1983-02-25
UA5971A1 (en) 1994-12-29
DK377882A (en) 1983-02-25
NL990010I2 (en) 1999-09-01
BE894175A (en) 1983-02-23
LV5511A3 (en) 1994-03-10
JPH045029B2 (en) 1992-01-30
NL990010I1 (en) 1999-07-01
LT2436B (en) 1994-02-15
GR76863B (en) 1984-09-04
GB2104522A (en) 1983-03-09
NZ201668A (en) 1985-08-16
LV5621A3 (en) 1994-05-10
IT1152505B (en) 1987-01-07
IL66606A (en) 1987-07-31
DK161147B (en) 1991-06-03
ATA319182A (en) 1985-09-15
AU571430B2 (en) 1988-04-21
HU186107B (en) 1985-06-28
FI822921A0 (en) 1982-08-23
IT8222938A0 (en) 1982-08-23
DE3231255A1 (en) 1983-03-03
JPS5843975A (en) 1983-03-14
SE8204817L (en) 1983-02-25
NL192739C (en) 1998-01-06
CH655114A5 (en) 1986-03-27
ES8400438A1 (en) 1983-11-01
IE822026L (en) 1983-02-24
LU84347A1 (en) 1983-06-07
IE53408B1 (en) 1988-11-09
IL66606A0 (en) 1982-12-31
SE448543B (en) 1987-03-02
SE8204817D0 (en) 1982-08-23
GEP19960641B (en) 1996-11-15
DE3231255C2 (en) 1992-02-27
FR2511679B1 (en) 1985-02-01
NL8203286A (en) 1983-03-16
CA1197247A (en) 1985-11-26
SU1447284A3 (en) 1988-12-23
GB2104522B (en) 1985-06-12
KR840001175A (en) 1984-03-28
FI73434C (en) 1987-10-09
ZA826120B (en) 1983-07-27
AT380256B (en) 1986-05-12
AU8749382A (en) 1983-03-03

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Legal Events

Date Code Title Description
A85 Still pending on 85-01-01
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
DNT Communications of changes of names of applicants whose applications have been laid open to public inspection

Free format text: MBL (1991) LIMITED

CNR Transfer of rights (patent application after its laying open for public inspection)

Free format text: CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED

AC1 Application for a supplementary protection certificate

Free format text: 990010, 19990401

KC1 Grant of a supplementary protection certificate

Free format text: 990010, 20020823, EXPIRES: 20070822

V4 Discontinued because of reaching the maximum lifetime of a patent

Free format text: 20020823