UA5971A1 - Method for producing [3h]-imidaso-[5,1-а]-1,2,3,5-tetrazine-4-on - Google Patents

Method for producing [3h]-imidaso-[5,1-а]-1,2,3,5-tetrazine-4-on

Info

Publication number
UA5971A1
UA5971A1 UA3482389A UA3482389A UA5971A1 UA 5971 A1 UA5971 A1 UA 5971A1 UA 3482389 A UA3482389 A UA 3482389A UA 3482389 A UA3482389 A UA 3482389A UA 5971 A1 UA5971 A1 UA 5971A1
Authority
UA
Ukraine
Prior art keywords
imidaso
tetrazine
producing
darkness
isocyanate
Prior art date
Application number
UA3482389A
Other languages
Russian (ru)
Ukrainian (uk)
Inventor
Лант Едвард
Френкіс Грахам Стівенс Малькольм
Стоун Роберт
Роберт Харрі Вулдрідж Кеннет
Original Assignee
Мбл (1991) Лімітед
МБЛ (1991) Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Мбл (1991) Лімітед, МБЛ (1991) Лимитед filed Critical Мбл (1991) Лімітед
Publication of UA5971A1 publication Critical patent/UA5971A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

The method for producing [3H]-imidaso-[5,1-a]-1,2,3,5-tetrazine-4-on provides for the reaction with isocyanate at the temperature ranging from the ambient to 30 °C in the darkness.
UA3482389A 1981-08-24 1982-08-23 Method for producing [3h]-imidaso-[5,1-а]-1,2,3,5-tetrazine-4-on UA5971A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8125791 1981-08-24

Publications (1)

Publication Number Publication Date
UA5971A1 true UA5971A1 (en) 1994-12-29

Family

ID=10524141

Family Applications (1)

Application Number Title Priority Date Filing Date
UA3482389A UA5971A1 (en) 1981-08-24 1982-08-23 Method for producing [3h]-imidaso-[5,1-а]-1,2,3,5-tetrazine-4-on

Country Status (29)

Country Link
JP (1) JPS5843975A (en)
KR (1) KR890000094B1 (en)
AT (1) AT380256B (en)
AU (1) AU571430B2 (en)
BE (1) BE894175A (en)
CA (1) CA1197247A (en)
CH (1) CH655114A5 (en)
DE (2) DE19975037I2 (en)
DK (1) DK161147C (en)
ES (1) ES8400438A1 (en)
FI (1) FI73434C (en)
FR (1) FR2511679A1 (en)
GB (1) GB2104522B (en)
GE (1) GEP19960641B (en)
GR (1) GR76863B (en)
HU (1) HU186107B (en)
IE (1) IE53408B1 (en)
IL (1) IL66606A (en)
IT (1) IT1152505B (en)
LT (1) LT2436B (en)
LU (1) LU84347A1 (en)
LV (2) LV5511A3 (en)
NL (2) NL192739C (en)
NZ (1) NZ201668A (en)
OA (1) OA07174A (en)
SE (1) SE448543B (en)
SU (1) SU1447284A3 (en)
UA (1) UA5971A1 (en)
ZA (1) ZA826120B (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260291A (en) * 1981-08-24 1993-11-09 Cancer Research Campaign Technology Limited Tetrazine derivatives
GB2125402B (en) * 1982-08-17 1985-11-13 May & Baker Ltd New tetrazine derivatives
FR2531958B1 (en) * 1982-08-17 1986-10-31 May & Baker Ltd NEW DERIVATIVES
US4517182A (en) * 1983-05-24 1985-05-14 Warner-Lambert Company 3-(Haloethyl)-4-oxopyrazolo-[5,1-d]-1,2,3,5-tetrazine-8-carboxamide composition
GB8616125D0 (en) * 1986-07-02 1986-08-06 May & Baker Ltd Compositions of matter
AU622330B2 (en) * 1989-06-23 1992-04-02 Takeda Chemical Industries Ltd. Condensed heterocyclic compounds having a nitrogen atom in the bridgehead for use as fungicides
EP1706407A2 (en) * 2003-12-30 2006-10-04 Chemagis Ltd. Novel crystalline forms of temozolomide
JP5475235B2 (en) 2005-01-21 2014-04-16 アステックス・セラピューティクス・リミテッド Pharmaceutical compounds
AR060635A1 (en) 2006-04-27 2008-07-02 Banyu Pharma Co Ltd DERIVATIVES OF 1,2-DIHIDRO-3H-PIRAZOLO [3,4-D] PIRIMIDIN-3-ONA, PHARMACEUTICAL COMPOSITIONS THAT INCLUDE THEM AND THEIR USE IN THE TREATMENT OF CANCER
JP2008081492A (en) 2006-08-31 2008-04-10 Banyu Pharmaceut Co Ltd New aminopyridine derivative having aurora a selective inhibitory action
WO2008044045A1 (en) 2006-10-12 2008-04-17 Astex Therapeutics Limited Pharmaceutical combinations
EP2073803B1 (en) 2006-10-12 2018-09-19 Astex Therapeutics Limited Pharmaceutical combinations
AU2008315048A1 (en) 2007-10-23 2009-04-30 Msd K.K. Pyridone-substituted-dihydropyrazolopyrimidinone derivative
PE20091101A1 (en) 2007-12-18 2009-07-26 Pharminox Ltd 3-SUBSTITUTED-4-OXO-3,4-DIHYDRO-IMIDAZO [5,1-d] [1,2,3,5-TETRACINE-8-CARBOXYL ACID AMIDES AND ITS USE
KR20110111383A (en) * 2008-11-24 2011-10-11 리라이언스 라이프 사이언시스 프라이빗. 리미티드 Process for the preparation of tetrazine derivatives
EP2403339B1 (en) 2009-03-06 2017-01-18 Merck Sharp & Dohme Corp. Combination cancer therapy with an akt inhibitor and other anticancer agents
AU2010264339A1 (en) 2009-06-23 2011-12-22 Pharminox Limited 3-substituted-8-substituted-3H imidazo[5,1-d][1,2,3,5-tetrazin-4-one compounds and their use
RU2462466C1 (en) * 2011-06-24 2012-09-27 Автономная Некоммерческая Организация "Научно-Исследовательский Центр Биотехнологии Антибиотиков И Других Биологически Активных Веществ "Биоан" Substituted azolo[1,2,4,5]tetrazines - inhibitors of antibacterial serine-threonine protein kinases
EP2766041B1 (en) 2011-10-12 2018-12-05 Children's Medical Center Corporation Combinatorial compositions and methods of treating hemoglobinopathies
BR112018068565A2 (en) 2016-03-15 2019-02-12 Oryzon Genomics, S.A. lsd1 inhibitor combinations for use in treating solid tumors
KR101847342B1 (en) * 2017-05-08 2018-04-11 (주)센텍코리아 Wearable body fat burning measurement device

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2932305A1 (en) * 1979-08-09 1981-02-26 Basf Ag Pyrrolo-, pyrazolo-, imidazo- and thiazolo-tetrazin-4-one derivs. - prepd. from amino-azole cpds. by diazotisation and reaction with isocyanate

Also Published As

Publication number Publication date
FI73434C (en) 1987-10-09
NL8203286A (en) 1983-03-16
NL990010I1 (en) 1999-07-01
FI822921A0 (en) 1982-08-23
GEP19960641B (en) 1996-11-15
GB2104522B (en) 1985-06-12
FI822921L (en) 1983-02-25
ES515176A0 (en) 1983-11-01
FR2511679A1 (en) 1983-02-25
SE8204817L (en) 1983-02-25
SE448543B (en) 1987-03-02
NL990010I2 (en) 1999-09-01
DK161147C (en) 1991-11-18
NZ201668A (en) 1985-08-16
JPH045029B2 (en) 1992-01-30
AU8749382A (en) 1983-03-03
AU571430B2 (en) 1988-04-21
BE894175A (en) 1983-02-23
IT1152505B (en) 1987-01-07
LT2436B (en) 1994-02-15
ZA826120B (en) 1983-07-27
CA1197247A (en) 1985-11-26
CH655114A5 (en) 1986-03-27
IL66606A0 (en) 1982-12-31
AT380256B (en) 1986-05-12
GR76863B (en) 1984-09-04
DE19975037I2 (en) 2001-06-13
IT8222938A0 (en) 1982-08-23
KR840001175A (en) 1984-03-28
KR890000094B1 (en) 1989-03-07
NL192739C (en) 1998-01-06
HU186107B (en) 1985-06-28
IE53408B1 (en) 1988-11-09
LV5511A3 (en) 1994-03-10
FI73434B (en) 1987-06-30
ATA319182A (en) 1985-09-15
SU1447284A3 (en) 1988-12-23
IE822026L (en) 1983-02-24
DK377882A (en) 1983-02-25
OA07174A (en) 1984-04-30
IL66606A (en) 1987-07-31
DE3231255A1 (en) 1983-03-03
DK161147B (en) 1991-06-03
LV5621A3 (en) 1994-05-10
JPS5843975A (en) 1983-03-14
GB2104522A (en) 1983-03-09
DE3231255C2 (en) 1992-02-27
ES8400438A1 (en) 1983-11-01
FR2511679B1 (en) 1985-02-01
LU84347A1 (en) 1983-06-07
NL192739B (en) 1997-09-01
SE8204817D0 (en) 1982-08-23

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