IT1152505B - DERIVATIVES OF A TETRAZINE - Google Patents

DERIVATIVES OF A TETRAZINE

Info

Publication number
IT1152505B
IT1152505B IT22938/82A IT2293882A IT1152505B IT 1152505 B IT1152505 B IT 1152505B IT 22938/82 A IT22938/82 A IT 22938/82A IT 2293882 A IT2293882 A IT 2293882A IT 1152505 B IT1152505 B IT 1152505B
Authority
IT
Italy
Prior art keywords
tetrazine
derivatives
Prior art date
Application number
IT22938/82A
Other languages
Italian (it)
Other versions
IT8222938A0 (en
Inventor
Edward Lunt
Malcolm Francis Graham Stevens
Robert Stone
Kenneth Robert Harr Wooldridge
Original Assignee
May & Baker Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by May & Baker Ltd filed Critical May & Baker Ltd
Publication of IT8222938A0 publication Critical patent/IT8222938A0/en
Application granted granted Critical
Publication of IT1152505B publication Critical patent/IT1152505B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
IT22938/82A 1981-08-24 1982-08-23 DERIVATIVES OF A TETRAZINE IT1152505B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8125791 1981-08-24

Publications (2)

Publication Number Publication Date
IT8222938A0 IT8222938A0 (en) 1982-08-23
IT1152505B true IT1152505B (en) 1987-01-07

Family

ID=10524141

Family Applications (1)

Application Number Title Priority Date Filing Date
IT22938/82A IT1152505B (en) 1981-08-24 1982-08-23 DERIVATIVES OF A TETRAZINE

Country Status (29)

Country Link
JP (1) JPS5843975A (en)
KR (1) KR890000094B1 (en)
AT (1) AT380256B (en)
AU (1) AU571430B2 (en)
BE (1) BE894175A (en)
CA (1) CA1197247A (en)
CH (1) CH655114A5 (en)
DE (2) DE3231255A1 (en)
DK (1) DK161147C (en)
ES (1) ES8400438A1 (en)
FI (1) FI73434C (en)
FR (1) FR2511679A1 (en)
GB (1) GB2104522B (en)
GE (1) GEP19960641B (en)
GR (1) GR76863B (en)
HU (1) HU186107B (en)
IE (1) IE53408B1 (en)
IL (1) IL66606A (en)
IT (1) IT1152505B (en)
LT (1) LT2436B (en)
LU (1) LU84347A1 (en)
LV (2) LV5511A3 (en)
NL (2) NL192739C (en)
NZ (1) NZ201668A (en)
OA (1) OA07174A (en)
SE (1) SE448543B (en)
SU (1) SU1447284A3 (en)
UA (1) UA5971A1 (en)
ZA (1) ZA826120B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260291A (en) * 1981-08-24 1993-11-09 Cancer Research Campaign Technology Limited Tetrazine derivatives

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2125402B (en) * 1982-08-17 1985-11-13 May & Baker Ltd New tetrazine derivatives
FR2531958B1 (en) * 1982-08-17 1986-10-31 May & Baker Ltd NEW DERIVATIVES
US4517182A (en) * 1983-05-24 1985-05-14 Warner-Lambert Company 3-(Haloethyl)-4-oxopyrazolo-[5,1-d]-1,2,3,5-tetrazine-8-carboxamide composition
GB8616125D0 (en) * 1986-07-02 1986-08-06 May & Baker Ltd Compositions of matter
AU622330B2 (en) * 1989-06-23 1992-04-02 Takeda Chemical Industries Ltd. Condensed heterocyclic compounds having a nitrogen atom in the bridgehead for use as fungicides
BRPI0417117A (en) * 2003-12-30 2007-03-06 Chemagis Ltd crystallized temozolomide, crystallized temozolomide preparation process, pharmaceutical composition, method of producing medicament containing temozolomide and method of treating a medical condition for which thermozolomide is beneficial
US20090036435A1 (en) 2005-01-21 2009-02-05 Astex Therapeutics Limited Pharmaceutical Compounds
AR060635A1 (en) 2006-04-27 2008-07-02 Banyu Pharma Co Ltd DERIVATIVES OF 1,2-DIHIDRO-3H-PIRAZOLO [3,4-D] PIRIMIDIN-3-ONA, PHARMACEUTICAL COMPOSITIONS THAT INCLUDE THEM AND THEIR USE IN THE TREATMENT OF CANCER
JP2008081492A (en) 2006-08-31 2008-04-10 Banyu Pharmaceut Co Ltd New aminopyridine derivative having aurora a selective inhibitory action
US8916552B2 (en) 2006-10-12 2014-12-23 Astex Therapeutics Limited Pharmaceutical combinations
EP2073807A1 (en) 2006-10-12 2009-07-01 Astex Therapeutics Limited Pharmaceutical combinations
CA2703489A1 (en) 2007-10-23 2009-04-30 Banyu Pharmaceutical Co., Ltd. Pyridone-substituted-dihydropyrazolopyrimidinone derivative
PE20091101A1 (en) * 2007-12-18 2009-07-26 Pharminox Ltd 3-SUBSTITUTED-4-OXO-3,4-DIHYDRO-IMIDAZO [5,1-d] [1,2,3,5-TETRACINE-8-CARBOXYL ACID AMIDES AND ITS USE
CA2744560A1 (en) * 2008-11-24 2010-05-27 Reliance Life Sciences Pvt. Ltd. Process for the preparation of tetrazine derivatives
EP2403339B1 (en) 2009-03-06 2017-01-18 Merck Sharp & Dohme Corp. Combination cancer therapy with an akt inhibitor and other anticancer agents
EP2445915B1 (en) 2009-06-23 2016-04-20 Pharminox Limited 3-substituted-8-substituted-3h imidazo[5,1-d][1,2,3,5-tetrazin-4-one compounds and their use
RU2462466C1 (en) * 2011-06-24 2012-09-27 Автономная Некоммерческая Организация "Научно-Исследовательский Центр Биотехнологии Антибиотиков И Других Биологически Активных Веществ "Биоан" Substituted azolo[1,2,4,5]tetrazines - inhibitors of antibacterial serine-threonine protein kinases
US20140271657A1 (en) 2011-10-12 2014-09-18 Children's Medical Center Corporation Combinatorial compositions and methods of treating hemoglobinopathies
CN109195593A (en) 2016-03-15 2019-01-11 奥莱松基因组股份有限公司 For treating the combination of the LSD1 inhibitor of solid tumor
KR101847342B1 (en) * 2017-05-08 2018-04-11 (주)센텍코리아 Wearable body fat burning measurement device

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2932305A1 (en) * 1979-08-09 1981-02-26 Basf Ag Pyrrolo-, pyrazolo-, imidazo- and thiazolo-tetrazin-4-one derivs. - prepd. from amino-azole cpds. by diazotisation and reaction with isocyanate

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260291A (en) * 1981-08-24 1993-11-09 Cancer Research Campaign Technology Limited Tetrazine derivatives

Also Published As

Publication number Publication date
GR76863B (en) 1984-09-04
FR2511679B1 (en) 1985-02-01
SU1447284A3 (en) 1988-12-23
DE19975037I2 (en) 2001-06-13
FR2511679A1 (en) 1983-02-25
IL66606A (en) 1987-07-31
NZ201668A (en) 1985-08-16
JPS5843975A (en) 1983-03-14
CA1197247A (en) 1985-11-26
KR890000094B1 (en) 1989-03-07
DK377882A (en) 1983-02-25
BE894175A (en) 1983-02-23
DE3231255A1 (en) 1983-03-03
IE822026L (en) 1983-02-24
SE448543B (en) 1987-03-02
NL192739C (en) 1998-01-06
FI822921A0 (en) 1982-08-23
DK161147C (en) 1991-11-18
CH655114A5 (en) 1986-03-27
NL8203286A (en) 1983-03-16
ES515176A0 (en) 1983-11-01
ZA826120B (en) 1983-07-27
NL192739B (en) 1997-09-01
OA07174A (en) 1984-04-30
AU8749382A (en) 1983-03-03
DK161147B (en) 1991-06-03
KR840001175A (en) 1984-03-28
SE8204817D0 (en) 1982-08-23
LV5511A3 (en) 1994-03-10
FI73434B (en) 1987-06-30
GB2104522A (en) 1983-03-09
FI73434C (en) 1987-10-09
ES8400438A1 (en) 1983-11-01
AT380256B (en) 1986-05-12
GEP19960641B (en) 1996-11-15
UA5971A1 (en) 1994-12-29
HU186107B (en) 1985-06-28
LU84347A1 (en) 1983-06-07
IL66606A0 (en) 1982-12-31
SE8204817L (en) 1983-02-25
DE3231255C2 (en) 1992-02-27
LV5621A3 (en) 1994-05-10
NL990010I1 (en) 1999-07-01
JPH045029B2 (en) 1992-01-30
IT8222938A0 (en) 1982-08-23
LT2436B (en) 1994-02-15
ATA319182A (en) 1985-09-15
IE53408B1 (en) 1988-11-09
FI822921L (en) 1983-02-25
GB2104522B (en) 1985-06-12
NL990010I2 (en) 1999-09-01
AU571430B2 (en) 1988-04-21

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Legal Events

Date Code Title Description
MED Supplementary protection certificate for pharmaceutical products: no action taken

Free format text: CCP 663, 19990709; CANCER RESEARCH CAMPAIGN TECHN.LTD.

MEDD Supplementary protection certificate for pharmaceutical products: granted

Free format text: CCP 663, 19990709; CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED

TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970829