DE19975037I2 - 3H-Imidazo-5,1-d-1,2,3,5-tetrazin-4-one derivatives Process for their preparation and pharmaceutical compositions containing them - Google Patents

3H-Imidazo-5,1-d-1,2,3,5-tetrazin-4-one derivatives Process for their preparation and pharmaceutical compositions containing them

Info

Publication number
DE19975037I2
DE19975037I2 DE1999175037 DE19975037C DE19975037I2 DE 19975037 I2 DE19975037 I2 DE 19975037I2 DE 1999175037 DE1999175037 DE 1999175037 DE 19975037 C DE19975037 C DE 19975037C DE 19975037 I2 DE19975037 I2 DE 19975037I2
Authority
DE
Germany
Prior art keywords
tetrazin
imidazo
preparation
pharmaceutical compositions
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE1999175037
Other languages
German (de)
Inventor
Edward Lunt
Malcolm Francis Graham Stevens
Robert Stone
Kenneth Robert Harr Wooldridge
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cancer Research Campaign Technology Ltd
Original Assignee
Cancer Research Campaign Technology Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cancer Research Campaign Technology Ltd filed Critical Cancer Research Campaign Technology Ltd
Application granted granted Critical
Publication of DE19975037I2 publication Critical patent/DE19975037I2/en
Active legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
DE1999175037 1981-08-24 1982-08-23 3H-Imidazo-5,1-d-1,2,3,5-tetrazin-4-one derivatives Process for their preparation and pharmaceutical compositions containing them Active DE19975037I2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8125791 1981-08-24

Publications (1)

Publication Number Publication Date
DE19975037I2 true DE19975037I2 (en) 2001-06-13

Family

ID=10524141

Family Applications (2)

Application Number Title Priority Date Filing Date
DE1999175037 Active DE19975037I2 (en) 1981-08-24 1982-08-23 3H-Imidazo-5,1-d-1,2,3,5-tetrazin-4-one derivatives Process for their preparation and pharmaceutical compositions containing them
DE19823231255 Granted DE3231255A1 (en) 1981-08-24 1982-08-23 Tetrazine derivatives, process for their preparation and pharmaceutical compositions containing them

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE19823231255 Granted DE3231255A1 (en) 1981-08-24 1982-08-23 Tetrazine derivatives, process for their preparation and pharmaceutical compositions containing them

Country Status (29)

Country Link
JP (1) JPS5843975A (en)
KR (1) KR890000094B1 (en)
AT (1) AT380256B (en)
AU (1) AU571430B2 (en)
BE (1) BE894175A (en)
CA (1) CA1197247A (en)
CH (1) CH655114A5 (en)
DE (2) DE19975037I2 (en)
DK (1) DK161147C (en)
ES (1) ES8400438A1 (en)
FI (1) FI73434C (en)
FR (1) FR2511679A1 (en)
GB (1) GB2104522B (en)
GE (1) GEP19960641B (en)
GR (1) GR76863B (en)
HU (1) HU186107B (en)
IE (1) IE53408B1 (en)
IL (1) IL66606A (en)
IT (1) IT1152505B (en)
LT (1) LT2436B (en)
LU (1) LU84347A1 (en)
LV (2) LV5511A3 (en)
NL (2) NL192739C (en)
NZ (1) NZ201668A (en)
OA (1) OA07174A (en)
SE (1) SE448543B (en)
SU (1) SU1447284A3 (en)
UA (1) UA5971A1 (en)
ZA (1) ZA826120B (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260291A (en) * 1981-08-24 1993-11-09 Cancer Research Campaign Technology Limited Tetrazine derivatives
FR2531958B1 (en) * 1982-08-17 1986-10-31 May & Baker Ltd NEW DERIVATIVES
GB2125402B (en) * 1982-08-17 1985-11-13 May & Baker Ltd New tetrazine derivatives
US4517182A (en) * 1983-05-24 1985-05-14 Warner-Lambert Company 3-(Haloethyl)-4-oxopyrazolo-[5,1-d]-1,2,3,5-tetrazine-8-carboxamide composition
GB8616125D0 (en) * 1986-07-02 1986-08-06 May & Baker Ltd Compositions of matter
AU622330B2 (en) * 1989-06-23 1992-04-02 Takeda Chemical Industries Ltd. Condensed heterocyclic compounds having a nitrogen atom in the bridgehead for use as fungicides
EP1706407A2 (en) * 2003-12-30 2006-10-04 Chemagis Ltd. Novel crystalline forms of temozolomide
ES2552338T3 (en) 2005-01-21 2015-11-27 Astex Therapeutics Limited Pharmaceutical compounds
AR060635A1 (en) 2006-04-27 2008-07-02 Banyu Pharma Co Ltd DERIVATIVES OF 1,2-DIHIDRO-3H-PIRAZOLO [3,4-D] PIRIMIDIN-3-ONA, PHARMACEUTICAL COMPOSITIONS THAT INCLUDE THEM AND THEIR USE IN THE TREATMENT OF CANCER
JP2008081492A (en) 2006-08-31 2008-04-10 Banyu Pharmaceut Co Ltd New aminopyridine derivative having aurora a selective inhibitory action
EP2073807A1 (en) 2006-10-12 2009-07-01 Astex Therapeutics Limited Pharmaceutical combinations
US8916552B2 (en) 2006-10-12 2014-12-23 Astex Therapeutics Limited Pharmaceutical combinations
AU2008315048A1 (en) 2007-10-23 2009-04-30 Msd K.K. Pyridone-substituted-dihydropyrazolopyrimidinone derivative
PE20091101A1 (en) 2007-12-18 2009-07-26 Pharminox Ltd 3-SUBSTITUTED-4-OXO-3,4-DIHYDRO-IMIDAZO [5,1-d] [1,2,3,5-TETRACINE-8-CARBOXYL ACID AMIDES AND ITS USE
EP2367828B1 (en) * 2008-11-24 2014-06-11 Reliance Life Sciences Pvt., Ltd. Process for the preparation of tetrazine derivatives
EP2403339B1 (en) 2009-03-06 2017-01-18 Merck Sharp & Dohme Corp. Combination cancer therapy with an akt inhibitor and other anticancer agents
JP2012530775A (en) 2009-06-23 2012-12-06 ファーミノックス リミテッド 3-substituted-8-substituted-3H-imidazo [5,1-d] [1,2,3,5-tetrazin-4-one compounds and uses thereof
RU2462466C1 (en) * 2011-06-24 2012-09-27 Автономная Некоммерческая Организация "Научно-Исследовательский Центр Биотехнологии Антибиотиков И Других Биологически Активных Веществ "Биоан" Substituted azolo[1,2,4,5]tetrazines - inhibitors of antibacterial serine-threonine protein kinases
US20140271657A1 (en) 2011-10-12 2014-09-18 Children's Medical Center Corporation Combinatorial compositions and methods of treating hemoglobinopathies
EA201892075A1 (en) 2016-03-15 2019-04-30 Оризон Дженомикс, С.А. COMBINATION OF LSD1 INHIBITORS FOR USE FOR THE TREATMENT OF SOLID TUMORS
KR101847342B1 (en) * 2017-05-08 2018-04-11 (주)센텍코리아 Wearable body fat burning measurement device

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2932305A1 (en) * 1979-08-09 1981-02-26 Basf Ag Pyrrolo-, pyrazolo-, imidazo- and thiazolo-tetrazin-4-one derivs. - prepd. from amino-azole cpds. by diazotisation and reaction with isocyanate

Also Published As

Publication number Publication date
KR890000094B1 (en) 1989-03-07
FI822921L (en) 1983-02-25
DK161147C (en) 1991-11-18
NL192739B (en) 1997-09-01
ES515176A0 (en) 1983-11-01
FI73434B (en) 1987-06-30
OA07174A (en) 1984-04-30
FR2511679A1 (en) 1983-02-25
UA5971A1 (en) 1994-12-29
DK377882A (en) 1983-02-25
NL990010I2 (en) 1999-09-01
BE894175A (en) 1983-02-23
LV5511A3 (en) 1994-03-10
JPH045029B2 (en) 1992-01-30
NL990010I1 (en) 1999-07-01
LT2436B (en) 1994-02-15
GR76863B (en) 1984-09-04
GB2104522A (en) 1983-03-09
NZ201668A (en) 1985-08-16
LV5621A3 (en) 1994-05-10
IT1152505B (en) 1987-01-07
IL66606A (en) 1987-07-31
DK161147B (en) 1991-06-03
ATA319182A (en) 1985-09-15
AU571430B2 (en) 1988-04-21
HU186107B (en) 1985-06-28
FI822921A0 (en) 1982-08-23
IT8222938A0 (en) 1982-08-23
DE3231255A1 (en) 1983-03-03
JPS5843975A (en) 1983-03-14
SE8204817L (en) 1983-02-25
NL192739C (en) 1998-01-06
CH655114A5 (en) 1986-03-27
ES8400438A1 (en) 1983-11-01
IE822026L (en) 1983-02-24
LU84347A1 (en) 1983-06-07
IE53408B1 (en) 1988-11-09
IL66606A0 (en) 1982-12-31
SE448543B (en) 1987-03-02
SE8204817D0 (en) 1982-08-23
GEP19960641B (en) 1996-11-15
DE3231255C2 (en) 1992-02-27
FR2511679B1 (en) 1985-02-01
NL8203286A (en) 1983-03-16
CA1197247A (en) 1985-11-26
SU1447284A3 (en) 1988-12-23
GB2104522B (en) 1985-06-12
KR840001175A (en) 1984-03-28
FI73434C (en) 1987-10-09
ZA826120B (en) 1983-07-27
AT380256B (en) 1986-05-12
AU8749382A (en) 1983-03-03

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