MY149862A - Compounds useful to treat retroviral infections - Google Patents
Compounds useful to treat retroviral infectionsInfo
- Publication number
- MY149862A MY149862A MYPI20051072A MYPI0501072A MY149862A MY 149862 A MY149862 A MY 149862A MY PI20051072 A MYPI20051072 A MY PI20051072A MY PI0501072 A MYPI0501072 A MY PI0501072A MY 149862 A MY149862 A MY 149862A
- Authority
- MY
- Malaysia
- Prior art keywords
- compounds useful
- ones
- retroviral infections
- pyran
- treat retroviral
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 206010038997 Retroviral infections Diseases 0.000 title 1
- 241001430294 unidentified retrovirus Species 0.000 abstract 2
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 210000004962 mammalian cell Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/32—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D309/36—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
- C07D309/38—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms one oxygen atom in position 2 or 4, e.g. pyrones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/74—Benzo[b]pyrans, hydrogenated in the carbocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrane Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23881794A | 1994-05-06 | 1994-05-06 | |
| US34936194A | 1994-12-02 | 1994-12-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY149862A true MY149862A (en) | 2013-10-31 |
Family
ID=26931995
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MYPI20051072A MY149862A (en) | 1994-05-06 | 1995-05-05 | Compounds useful to treat retroviral infections |
| MYPI95001195A MY127701A (en) | 1994-05-06 | 1995-05-05 | Pyranone compounds useful to treat retroviral infections |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MYPI95001195A MY127701A (en) | 1994-05-06 | 1995-05-05 | Pyranone compounds useful to treat retroviral infections |
Country Status (32)
Families Citing this family (74)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL129871A (en) * | 1994-05-06 | 2003-11-23 | Pharmacia & Upjohn Inc | Process for preparing 4-phenyl-substituted octanoyl-oxazolidin-2-one intermediates that are useful for preparing pyran-2-ones useful for treating retroviral infections |
| US5914332A (en) | 1995-12-13 | 1999-06-22 | Abbott Laboratories | Retroviral protease inhibiting compounds |
| EP0909184B1 (en) * | 1996-07-03 | 2003-09-17 | PHARMACIA & UPJOHN COMPANY | Targeted drug delivery using sulfonamide derivatives |
| US5834506A (en) * | 1996-11-01 | 1998-11-10 | Warner-Lambert Company | Dihydropyrones with improved antiviral activity |
| US6232333B1 (en) | 1996-11-21 | 2001-05-15 | Abbott Laboratories | Pharmaceutical composition |
| ATE265847T1 (de) * | 1997-07-29 | 2004-05-15 | Upjohn Co | Selbstemulgierbare formulierung enthaltend lipophile verbindungen |
| RU2202346C2 (ru) * | 1997-07-29 | 2003-04-20 | Фармация Энд Апджон Компани | Фармацевтическая композиция для кислотных липофильных соединений в форме самоэмульгирующейся композиции |
| US6121313A (en) | 1997-07-29 | 2000-09-19 | Pharmacia & Upjohn Company | Pharmaceutical composition in a form of self-emulsifying formulation for lipophilic compounds |
| RU2223958C2 (ru) * | 1997-09-11 | 2004-02-20 | Фармация Энд Апджон Компани | Новый способ получения ингибитора протеазы |
| DK1161427T3 (da) * | 1999-03-18 | 2003-02-24 | Upjohn Co | Forbedret fremgangsmåde til asymmetrisk hydrogenering |
| US6956048B2 (en) * | 1999-03-31 | 2005-10-18 | Pharmacia & Upjohn Company | Pharmaceutical emulsions for retroviral protease inhibitors |
| DE60038899D1 (de) | 2000-01-19 | 2008-06-26 | Abbott Lab | Hiv-proteasehemmern |
| FI113942B (fi) * | 2000-08-18 | 2004-07-15 | Control Ox Oy | Kasviperäisten fenolisten yhdisteiden käyttö valmistettaessa klamydiainfektion hoidossa ja ennaltaehkäisyssä käyttökelpoista farmaseuttista valmistetta, terveyteen myönteisesti vaikuttavaa ravintoainekoostumusta tai koostumusta lisättäväksi tällaisiin elintarvikkeisiin |
| DE10108470A1 (de) * | 2001-02-22 | 2002-09-05 | Boehringer Ingelheim Pharma | Verfahren zur Herstellung optisch aktiver Dihydropyrone |
| US6500963B2 (en) | 2001-02-22 | 2002-12-31 | Boehringer Ingelheim Pharma Kg | Process for preparing optically active dihydropyrones |
| PT1485377E (pt) * | 2002-02-25 | 2010-03-12 | Kudos Pharm Ltd | Piranonas úteis como inibidores da atm |
| BR0308856A (pt) * | 2002-04-01 | 2005-02-22 | Pfizer | Piranon e pirandion inibidores do rna polimerase dependente do rna do vìrus da hepatite c |
| RU2234535C2 (ru) * | 2002-10-03 | 2004-08-20 | Государственный научный центр вирусологии и биотехнологии "Вектор" | Субстрат для определения активности интегразы вируса иммунодефицита человека |
| US8025899B2 (en) | 2003-08-28 | 2011-09-27 | Abbott Laboratories | Solid pharmaceutical dosage form |
| US8377952B2 (en) | 2003-08-28 | 2013-02-19 | Abbott Laboratories | Solid pharmaceutical dosage formulation |
| US8841326B2 (en) | 2004-02-12 | 2014-09-23 | Stc.Unm | Therapeutic curcumin derivatives |
| IL161586A (en) * | 2004-04-22 | 2015-02-26 | Rafael Advanced Defense Sys | Irreplaceable energetic material and reactive shielding that uses it |
| US20060106043A1 (en) * | 2004-11-08 | 2006-05-18 | Boehringer Ingelheim International Gmbh | Method for treating HIV infection through co-administration of tipranavir and etravirine |
| US20060135562A1 (en) * | 2004-11-16 | 2006-06-22 | Boehringer Ingelheim International Gmbh | Method for treating HIV infection through co-administration of tipranavir and darunavir |
| US20060122220A1 (en) * | 2004-11-19 | 2006-06-08 | Boehringer Ingelheim International Gmbh | Method for treating HIV infection through co-administration of tipranavir and UK-427,857 |
| JP2008520701A (ja) * | 2004-11-19 | 2008-06-19 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | チプラナビル及びレバーセットの同時投与を介したｈｉｖ感染症の治療方法 |
| JP2008521897A (ja) * | 2004-12-01 | 2008-06-26 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | チプラナビル及びｓｃｈ−４１７６９０を共に投与することを含むｈｉｖ感染症の治療方法 |
| JP2008521898A (ja) * | 2004-12-01 | 2008-06-26 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | チプラナビル及びｇｗ８７３１４０を共に投与することを含むｈｉｖ感染症の治療方法 |
| EP1819348A1 (en) * | 2004-12-01 | 2007-08-22 | Boehringer Ingelheim International Gmbh | Method for treating hiv infection through co-administration of tipranavir and gw695634 |
| CA2679482C (en) | 2007-03-12 | 2015-04-21 | Nektar Therapeutics | Oligomer-protease inhibitor conjugates |
| US20090062346A1 (en) * | 2007-08-29 | 2009-03-05 | Protia, Llc | Deuterium-enriched tipranavir |
| US20100093811A1 (en) * | 2007-09-25 | 2010-04-15 | Coburn Craig A | Hiv protease inhibitors |
| KR101076680B1 (ko) * | 2007-11-01 | 2011-10-26 | 한미홀딩스 주식회사 | (6ｒ)-3-헥실-4-히드록시-6-운데실-5,6-다이히드로피란-2-온의 제조방법 및 이에 사용되는 중간체 |
| EP2262498A2 (en) * | 2008-03-10 | 2010-12-22 | Vertex Pharmceuticals Incorporated | Pyrimidines and pyridines useful as inhibitors of protein kinases |
| EP2262538B1 (en) | 2008-03-12 | 2014-12-10 | Nektar Therapeutics | Oligomer-amino acid conjugate |
| US8173621B2 (en) | 2008-06-11 | 2012-05-08 | Gilead Pharmasset Llc | Nucleoside cyclicphosphates |
| EP2376514A2 (en) | 2008-12-23 | 2011-10-19 | Pharmasset, Inc. | Nucleoside analogs |
| BRPI0923815A2 (pt) | 2008-12-23 | 2015-07-14 | Pharmasset Inc | Síntese de nucleosídeos de purina |
| EA019341B1 (ru) | 2008-12-23 | 2014-02-28 | Джилид Фармассет, Ллс. | Фосфорамидаты нуклеозидов |
| US8497383B2 (en) | 2009-05-27 | 2013-07-30 | Merck Sharp & Dohme Corp. | HIV protease inhibitors |
| WO2010144869A2 (en) | 2009-06-12 | 2010-12-16 | Nektar Therapeutics | Protease inhibitors |
| PL2442809T3 (pl) | 2009-06-17 | 2017-02-28 | Vertex Pharmaceuticals Incorporated | Inhibitory replikacji wirusów grypy |
| KR101466245B1 (ko) * | 2010-01-15 | 2014-12-01 | 한미사이언스 주식회사 | 테트라졸 메탄설폰산 염의 제조방법 및 이에 사용되는 신규 화합물 |
| LT2609923T (lt) | 2010-03-31 | 2017-09-11 | Gilead Pharmasset Llc | (s)-izopropilo 2-(((s)-(perfluorfenoksi)(fenoksi)fosforil)amino)-propanoato kristalinimo būdas |
| WO2012033846A1 (en) | 2010-09-09 | 2012-03-15 | Rutgers, The State University Of New Jersey | Arylpropionyl-triketone antibacterial agents |
| US8772332B2 (en) * | 2010-09-09 | 2014-07-08 | Richard H. Ebright | Arylpropionyl-alpha-pyrone antibacterial agents |
| US9133155B2 (en) | 2010-09-17 | 2015-09-15 | Rutgers, The State University Of New Jersey | Antibacterial agents: high-potency myxopyronin derivatives |
| EP2632895B1 (en) | 2010-10-28 | 2018-10-03 | Merck Canada Inc. | Hiv protease inhibitors |
| AU2011343642A1 (en) | 2010-12-16 | 2013-05-02 | Vertex Pharmaceuticals Incorporated | Inhibitors of influenza viruses replication |
| UA118010C2 (uk) | 2011-08-01 | 2018-11-12 | Вертекс Фармасьютікалз Інкорпорейтед | Інгібітори реплікації вірусів грипу |
| WO2013059928A1 (en) | 2011-10-26 | 2013-05-02 | Merck Canada Inc. | Hiv protease inhibitors |
| US9517994B2 (en) | 2012-01-05 | 2016-12-13 | Rutgers, The State University Of New Jersey | Antibacterial agents: phloroglucinol derivatives |
| RU2015113091A (ru) * | 2012-09-11 | 2016-11-10 | Мерк Шарп И Доум Корп. | Ингибиторы протеазы вич |
| AU2013340559B2 (en) | 2012-10-29 | 2018-03-15 | Cipla Limited | Antiviral phosphonate analogues and process for preparation thereof |
| WO2015013835A1 (en) | 2013-07-31 | 2015-02-05 | Merck Sharp & Dohme Corp. | Piperazine derivatives as hiv protease inhibitors |
| EP3421468B1 (en) | 2013-11-13 | 2020-11-04 | Vertex Pharmaceuticals Incorporated | Methods of preparing inhibitors of influenza viruses replication |
| LT3068776T (lt) | 2013-11-13 | 2019-08-12 | Vertex Pharmaceuticals Incorporated | Gripo virusų replikacijos inhibitoriai |
| WO2015095265A1 (en) | 2013-12-19 | 2015-06-25 | Merck Sharp & Dohme Corp. | Hiv protease inhibitors |
| US9834526B2 (en) | 2013-12-19 | 2017-12-05 | Merck Sharp & Dohme Corp. | HIV protease inhibitors |
| EP3113780B1 (en) | 2014-03-06 | 2019-08-14 | Merck Sharp & Dohme Corp. | Hiv protease inhibitors |
| US10138255B2 (en) | 2014-03-10 | 2018-11-27 | Merck Sharp & Dohme Corp. | Piperazine derivatives as HIV protease inhibitors |
| WO2016069955A1 (en) | 2014-10-29 | 2016-05-06 | Wisconsin Alumni Research Foundation | Boronic acid inhibitors of hiv protease |
| WO2016183120A1 (en) | 2015-05-13 | 2016-11-17 | Vertex Pharmaceuticals Incorporated | Inhibitors of influenza viruses replication |
| JP6704416B2 (ja) | 2015-05-13 | 2020-06-03 | バーテックス ファーマシューティカルズ インコーポレイテッドＶｅｒｔｅｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃｏｒｐｏｒａｔｅｄ | インフルエンザウイルスの複製の阻害剤を調製する方法 |
| WO2017100645A2 (en) | 2015-12-10 | 2017-06-15 | Rutgers, The State University Of New Jersey | Inhibitors of bacterial rna polymerase: arylpropanoyl, arylpropenoyl, and arylcyclopropanecarboxyl phloroglucinols |
| WO2017156458A1 (en) | 2016-03-11 | 2017-09-14 | University Of South Florida | Beta-lactamase inhibitors, formulations, and uses thereof |
| US11993590B2 (en) * | 2016-12-04 | 2024-05-28 | 712 North Inc. | Pyranone compounds useful to modulate OMA1 protease |
| EP3752142A4 (en) | 2018-02-13 | 2021-09-08 | Rutgers, The State University of New Jersey | ANTIBACTERIAL AGENTS: SOLUBLE SALTS AND AQUEOUS FORMULATIONS OF PYRONINS |
| US11685723B2 (en) | 2018-02-13 | 2023-06-27 | Rutgers, The State University Of New Jersey | Antibacterial agents: O-alkyl-deuterated pyronins |
| US11572337B2 (en) | 2018-03-06 | 2023-02-07 | Rutgers, The State University Of New Jersey | Antibacterial agents: arylalkylcarboxamido phloroglucinols |
| CN110551090B (zh) * | 2019-10-21 | 2021-06-18 | 扬州工业职业技术学院 | 一种超声波提取中药狗脊中抗肿瘤活性成分的方法 |
| WO2021209563A1 (en) | 2020-04-16 | 2021-10-21 | Som Innovation Biotech, S.A. | Compounds for use in the treatment of viral infections by respiratory syndrome-related coronavirus |
| WO2024130166A2 (en) * | 2022-12-16 | 2024-06-20 | Denali Therapeutics Inc. | Compounds, compositions, and methods |
| CN116730993A (zh) * | 2023-04-25 | 2023-09-12 | 浙江科技学院 | 一种替拉那韦中间体及替拉那韦的制备方法 |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB193507A (en) | 1921-11-25 | 1923-02-26 | English Electric Co Ltd | Improvements in and connected with hydraulic impulse turbines |
| NL80964C (cg-RX-API-DMAC7.html) * | 1952-03-08 | |||
| NL82169C (cg-RX-API-DMAC7.html) * | 1952-05-16 | |||
| US2723277A (en) * | 1952-08-26 | 1955-11-08 | Hoffmann La Roche | Malonic acid derivatives and process for the manufacture thereof |
| US2872457A (en) * | 1956-04-19 | 1959-02-03 | Wisconsin Alumni Res Found | Process for the preparation of 4-hydroxycoumarin derivatives |
| GB836740A (en) * | 1956-04-25 | 1960-06-09 | Bayer Ag | Coumarin derivatives and their production |
| FR1276654A (fr) * | 1958-10-01 | 1961-11-24 | Nouveaux dérivés de l'hydroxy-4-alpha-2-pyrone | |
| FR1463767A (fr) * | 1963-04-03 | 1966-07-22 | Clin Byla Ets | Dérivés de la coumarine et leur préparation |
| BE674997A (cg-RX-API-DMAC7.html) * | 1965-01-13 | 1966-07-12 | ||
| FR1559595A (cg-RX-API-DMAC7.html) * | 1966-12-13 | 1969-03-14 | ||
| US3489774A (en) * | 1967-04-24 | 1970-01-13 | Dow Chemical Co | 3-(beta-aryl-beta-(arylthio) (or arylseleno) propionyl)-coumarin products |
| US3493586A (en) * | 1969-01-23 | 1970-02-03 | Dow Chemical Co | 3-(beta-aryl-beta-(arylthio) (or arylseleno)-propionyl)pyrone products |
| JPS4823942B1 (cg-RX-API-DMAC7.html) * | 1969-02-14 | 1973-07-17 | ||
| US3764693A (en) * | 1969-11-21 | 1973-10-09 | Lipha | A rodenticidal compositions containing 4-hydroxy coumarins |
| US3835161A (en) * | 1972-10-24 | 1974-09-10 | Realisations Scient S E Res C | 3-substituted-4-hydroxy-coumarins |
| US3931235A (en) * | 1972-12-18 | 1976-01-06 | The Dow Chemical Company | Process for preparing sulfur-containing hydroxy pyrones |
| JPS53147073A (en) * | 1977-05-24 | 1978-12-21 | Sankyo Co Ltd | Mevalonolactone derivatives |
| NZ194557A (en) * | 1979-08-17 | 1984-09-28 | Merck & Co Inc | Substituted pyranone derivatives;dihydroxy acids therefrom;pharmaceutical compositions |
| CA1171424A (en) * | 1981-06-17 | 1984-07-24 | Alvin K. Willard | ( )-(4r, 6s) - (e)-6-[2-(4'fluro-3,3', 5-trimethyl- [l,l'-biphenyl]-2-yl)ethenyl]-3,4,5,6- tetrahydro-4-hydroxy-2h-pyran-2-one |
| JPS634652A (ja) * | 1986-06-25 | 1988-01-09 | Hitachi Ltd | 半導体装置 |
| AU1044088A (en) | 1986-12-17 | 1988-07-15 | Nippon Soda Co., Ltd. | Heterocyclic compounds having triketo skeleton |
| US4900754A (en) * | 1987-12-21 | 1990-02-13 | Rorer Pharmaceutical Corp. | HMG-COA reductase inhibitors |
| WO1989007939A2 (en) * | 1988-03-01 | 1989-09-08 | The Upjohn Company | Coumarins to inhibit reverse transcriptase in humans |
| DE3929913A1 (de) * | 1989-09-08 | 1991-04-04 | Hoechst Ag | 4-hydroxytetrahydropyran-2-one sowie die entsprechenden dihydroxycarbonsaeurederivate, salze und ester, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, pharmazeutische praeparate sowie vorprodukte |
| JPH05503073A (ja) * | 1989-09-26 | 1993-05-27 | オクタマー，インコーポレイテッド | ウイルス性疾患の治療に有用な６―アミノ―１，２―ベンゾピロン |
| JPH05501879A (ja) * | 1989-10-27 | 1993-04-08 | ジ・アップジョン・カンパニー | Ｈｉｖおよび他のレトロウイルスを処理する方法およびそれに有用な化合物 |
| JPH03227923A (ja) | 1990-01-30 | 1991-10-08 | Sawai Seiyaku Kk | ひと免疫不全ウイルス疾患処置剤 |
| SE9000624D0 (sv) * | 1990-02-22 | 1990-02-22 | Pharmacia Ab | New use |
| CA2035972C (en) * | 1990-02-23 | 2006-07-11 | Martin Karpf | Process for the preparation of oxetanones |
| US5382572A (en) * | 1990-09-07 | 1995-01-17 | Schering Corporation | Alkyl and acyl substituted quinolines |
| DE69128481T2 (de) * | 1990-09-07 | 1998-04-09 | Schering Corp | Antivirale und antihypertensive verbindungen |
| JPH06502845A (ja) * | 1990-09-07 | 1994-03-31 | シェリング・コーポレーション | 抗ウイルス化合物および抗高血圧化合物 |
| US5484951A (en) * | 1990-10-19 | 1996-01-16 | Octamer, Incorporated | 5-iodo-6-amino-6-nitroso-1,2-benzopyrones useful as cytostatic and antiviral agents |
| EP0578745A1 (en) * | 1991-04-04 | 1994-01-19 | The Upjohn Company | Phosphorus containing compounds as inhibitors of retroviruses |
| EP0765873B1 (en) * | 1991-10-11 | 2002-04-17 | Dupont Pharmaceuticals Company | Cyclic ureas and analogues useful as retroviral protease inhibitors |
| EP0609211A4 (en) * | 1991-10-22 | 1995-02-01 | Octamer Inc | NITROUS AROMATIC COMPOUNDS THAT BIND ADENOSINE DIPHOSPHORIBOSIS POLYMERASE AS EFFECTIVE ANTI-TUMOR AND ANTI-RETROVIRUS AGENTS. |
| DE4308451A1 (de) * | 1992-09-10 | 1994-04-14 | Bayer Ag | 3-Aryl-pyron-Derivate |
| ZA938019B (en) * | 1992-11-13 | 1995-04-28 | Upjohn Co | Pyran-2-ones and 5,6-dihydropyran-2-ones useful for treating HIV and other retroviruses |
| IL108459A0 (en) * | 1993-02-05 | 1994-04-12 | Opjohn Company | 4-Hydroxy-benzopyran-2-ones and 4-hydroxy-cycloalkyl [B] pyran-2-ones useful for treating infections due to hiv and other retroviruses |
| IL129871A (en) * | 1994-05-06 | 2003-11-23 | Pharmacia & Upjohn Inc | Process for preparing 4-phenyl-substituted octanoyl-oxazolidin-2-one intermediates that are useful for preparing pyran-2-ones useful for treating retroviral infections |
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1995
- 1995-05-01 IL IL12987195A patent/IL129871A/xx not_active IP Right Cessation
- 1995-05-04 CA CA002560489A patent/CA2560489C/en not_active Expired - Lifetime
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- 1995-05-04 AU AU24626/95A patent/AU701965B2/en not_active Expired
- 1995-05-04 DE DE1995630294 patent/DE122006000014I2/de active Active
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- 1995-05-04 SK SK1384-96A patent/SK284407B6/sk not_active IP Right Cessation
- 1995-05-04 CZ CZ0317296A patent/CZ296515B6/cs not_active IP Right Cessation
- 1995-05-04 AT AT95918864T patent/ATE236894T1/de active
- 1995-05-04 MX MX9605391A patent/MX9605391A/es active IP Right Grant
- 1995-05-04 BR BR9507615A patent/BR9507615A/pt active Search and Examination
- 1995-05-04 RU RU96123286A patent/RU2139284C1/ru active
- 1995-05-04 NZ NZ285510A patent/NZ285510A/en not_active IP Right Cessation
- 1995-05-04 JP JP52901695A patent/JP3883206B2/ja not_active Expired - Lifetime
- 1995-05-04 HU HU9603074A patent/HU228057B1/hu active Protection Beyond IP Right Term
- 1995-05-04 WO PCT/US1995/005219 patent/WO1995030670A2/en not_active Ceased
- 1995-05-04 SI SI9530660T patent/SI0758327T1/xx unknown
- 1995-05-04 CN CNB951935534A patent/CN1154642C/zh not_active Expired - Lifetime
- 1995-05-04 ES ES95918864T patent/ES2192201T3/es not_active Expired - Lifetime
- 1995-05-04 PL PL95317061A patent/PL190540B1/pl unknown
- 1995-05-04 US US08/809,224 patent/US5852195A/en not_active Expired - Lifetime
- 1995-05-04 CN CNB2004100346805A patent/CN1329378C/zh not_active Expired - Lifetime
- 1995-05-04 PT PT95918864T patent/PT758327E/pt unknown
- 1995-05-04 EP EP95918864A patent/EP0758327B1/en not_active Expired - Lifetime
- 1995-05-04 TW TW084104473A patent/TW504507B/zh not_active IP Right Cessation
- 1995-05-04 DK DK95918864T patent/DK0758327T3/da active
- 1995-05-04 KR KR1019960706245A patent/KR100445929B1/ko not_active Expired - Lifetime
- 1995-05-05 CO CO95018810A patent/CO4810313A1/es unknown
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1996
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- 1996-11-05 FI FI964441A patent/FI117387B/fi not_active IP Right Cessation
- 1996-11-05 NO NO19964676A patent/NO315799B1/no not_active IP Right Cessation
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1998
- 1998-11-09 US US09/188,998 patent/US6169181B1/en not_active Expired - Lifetime
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1999
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2005
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2006
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- 2006-03-02 NO NO2006003C patent/NO2006003I2/no unknown
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