FI964441A0 - Yhdisteet, jotka ovat käyttökelpoisia retrovirusinfektioiden hoitoon - Google Patents
Yhdisteet, jotka ovat käyttökelpoisia retrovirusinfektioiden hoitoonInfo
- Publication number
- FI964441A0 FI964441A0 FI964441A FI964441A FI964441A0 FI 964441 A0 FI964441 A0 FI 964441A0 FI 964441 A FI964441 A FI 964441A FI 964441 A FI964441 A FI 964441A FI 964441 A0 FI964441 A0 FI 964441A0
- Authority
- FI
- Finland
- Prior art keywords
- treatment
- compounds useful
- ones
- retroviral infections
- pyran
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 206010038997 Retroviral infections Diseases 0.000 title 1
- 241001430294 unidentified retrovirus Species 0.000 abstract 2
- QBDAFARLDLCWAT-UHFFFAOYSA-N 2,3-dihydropyran-6-one Chemical class O=C1OCCC=C1 QBDAFARLDLCWAT-UHFFFAOYSA-N 0.000 abstract 1
- ZPSJGADGUYYRKE-UHFFFAOYSA-N 2H-pyran-2-one Chemical class O=C1C=CC=CO1 ZPSJGADGUYYRKE-UHFFFAOYSA-N 0.000 abstract 1
- VXIXUWQIVKSKSA-UHFFFAOYSA-N 4-hydroxycoumarin Chemical class C1=CC=CC2=C1OC(=O)C=C2O VXIXUWQIVKSKSA-UHFFFAOYSA-N 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 210000004962 mammalian cell Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/32—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D309/36—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
- C07D309/38—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms one oxygen atom in position 2 or 4, e.g. pyrones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/74—Benzo[b]pyrans, hydrogenated in the carbocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23881794A | 1994-05-06 | 1994-05-06 | |
| US23881794 | 1994-05-06 | ||
| US34936194A | 1994-12-02 | 1994-12-02 | |
| US34936194 | 1994-12-02 | ||
| PCT/US1995/005219 WO1995030670A2 (en) | 1994-05-06 | 1995-05-04 | Pyranone compounds useful to treat retroviral infections |
| US9505219 | 1995-05-04 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI964441A FI964441A (fi) | 1996-11-05 |
| FI964441A0 true FI964441A0 (fi) | 1996-11-05 |
| FI117387B FI117387B (fi) | 2006-09-29 |
Family
ID=26931995
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI964441A FI117387B (fi) | 1994-05-06 | 1996-11-05 | Pyranoniyhdisteet, jotka ovat käyttökelpoisia retrovirusinfektioiden hoitoon |
Country Status (33)
| Country | Link |
|---|---|
| US (2) | US5852195A (fi) |
| EP (1) | EP0758327B1 (fi) |
| JP (1) | JP3883206B2 (fi) |
| KR (1) | KR100445929B1 (fi) |
| CN (2) | CN1154642C (fi) |
| AT (1) | ATE236894T1 (fi) |
| AU (2) | AU701965B2 (fi) |
| BR (1) | BR9507615A (fi) |
| CA (2) | CA2187523C (fi) |
| CO (1) | CO4810313A1 (fi) |
| CZ (1) | CZ296515B6 (fi) |
| DE (2) | DE69530294T2 (fi) |
| DK (1) | DK0758327T3 (fi) |
| ES (1) | ES2192201T3 (fi) |
| FI (1) | FI117387B (fi) |
| FR (1) | FR05C0047I2 (fi) |
| HK (2) | HK1066796A1 (fi) |
| HU (1) | HU228057B1 (fi) |
| IL (3) | IL129871A (fi) |
| LU (1) | LU91220I2 (fi) |
| MX (1) | MX9605391A (fi) |
| MY (2) | MY127701A (fi) |
| NL (1) | NL300216I2 (fi) |
| NO (2) | NO315799B1 (fi) |
| NZ (1) | NZ285510A (fi) |
| PE (1) | PE23196A1 (fi) |
| PL (1) | PL190540B1 (fi) |
| PT (1) | PT758327E (fi) |
| RU (1) | RU2139284C1 (fi) |
| SI (1) | SI0758327T1 (fi) |
| SK (1) | SK284407B6 (fi) |
| TW (1) | TW504507B (fi) |
| WO (1) | WO1995030670A2 (fi) |
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|---|---|---|---|---|
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| US5914332A (en) | 1995-12-13 | 1999-06-22 | Abbott Laboratories | Retroviral protease inhibiting compounds |
| WO1998000173A2 (en) * | 1996-07-03 | 1998-01-08 | Pharmacia & Upjohn Company | Targeted drug delivery using sulfonamide derivatives |
| US5834506A (en) * | 1996-11-01 | 1998-11-10 | Warner-Lambert Company | Dihydropyrones with improved antiviral activity |
| US6232333B1 (en) | 1996-11-21 | 2001-05-15 | Abbott Laboratories | Pharmaceutical composition |
| DE69808463T2 (de) | 1997-07-29 | 2003-06-26 | Upjohn Co | Selbstemulgierende formulierung enthaltend saure lipophile verbindungen |
| DE69804624T2 (de) * | 1997-07-29 | 2002-09-19 | Upjohn Co | Selbstemulgierende formulierung enthaltend lipophile verbindungen |
| ES2219895T3 (es) * | 1997-07-29 | 2004-12-01 | PHARMACIA & UPJOHN COMPANY | Formulacion autoemulsionante para compuestos lipofilos. |
| DK1015441T3 (da) * | 1997-09-11 | 2004-07-26 | Upjohn Co | Fremgangsmåde til fremstilling af 4-hydroxy-2-oxo-pyranderivater, der er nyttige som proteaseinhibitorer |
| DE60000660T2 (de) * | 1999-03-18 | 2003-06-26 | Upjohn Co | Verbesserte verfahren fur assymmetrische hydrogenation |
| US6956048B2 (en) * | 1999-03-31 | 2005-10-18 | Pharmacia & Upjohn Company | Pharmaceutical emulsions for retroviral protease inhibitors |
| DK2269591T3 (en) | 2000-01-19 | 2018-07-16 | Abbvie Inc | IMPROVED PHARMACEUTICAL FORMULATIONS |
| DE10108470A1 (de) * | 2001-02-22 | 2002-09-05 | Boehringer Ingelheim Pharma | Verfahren zur Herstellung optisch aktiver Dihydropyrone |
| US6500963B2 (en) | 2001-02-22 | 2002-12-31 | Boehringer Ingelheim Pharma Kg | Process for preparing optically active dihydropyrones |
| BR0307944A (pt) * | 2002-02-25 | 2005-02-01 | Kudos Pharm Ltd | Piranonas úteis como inibidores de atm |
| BR0308856A (pt) * | 2002-04-01 | 2005-02-22 | Pfizer | Piranon e pirandion inibidores do rna polimerase dependente do rna do vìrus da hepatite c |
| US8025899B2 (en) | 2003-08-28 | 2011-09-27 | Abbott Laboratories | Solid pharmaceutical dosage form |
| US8377952B2 (en) | 2003-08-28 | 2013-02-19 | Abbott Laboratories | Solid pharmaceutical dosage formulation |
| US8841326B2 (en) | 2004-02-12 | 2014-09-23 | Stc.Unm | Therapeutic curcumin derivatives |
| IL161586A (en) * | 2004-04-22 | 2015-02-26 | Rafael Advanced Defense Sys | Irreplaceable energetic material and reactive shielding that uses it |
| EP1812069A2 (en) * | 2004-11-08 | 2007-08-01 | Boehringer Ingelheim International GmbH | Method for treating hiv infection through co-administration of tipranavir and etravirine |
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| WO2006055660A2 (en) * | 2004-11-19 | 2006-05-26 | Boehringer Ingelheim International Gmbh | Method for treating hiv infection through co-administration of tipranavir and uk-427, 857 |
| US20060128733A1 (en) * | 2004-11-19 | 2006-06-15 | Boehringer Ingelheim International Gmbh | Method for treating HIV infection through co-administration of tipranavir and reverset |
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| US8173621B2 (en) | 2008-06-11 | 2012-05-08 | Gilead Pharmasset Llc | Nucleoside cyclicphosphates |
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| US8551973B2 (en) | 2008-12-23 | 2013-10-08 | Gilead Pharmasset Llc | Nucleoside analogs |
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| RS55341B1 (sr) | 2009-06-17 | 2017-03-31 | Vertex Pharma | Inhibitori replikacije virusa gripa |
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| US10138255B2 (en) | 2014-03-10 | 2018-11-27 | Merck Sharp & Dohme Corp. | Piperazine derivatives as HIV protease inhibitors |
| EP3212196A4 (en) | 2014-10-29 | 2018-07-11 | Wisconsin Alumni Research Foundation | Boronic acid inhibitors of hiv protease |
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| US10450292B2 (en) | 2015-12-10 | 2019-10-22 | Rutgers, The State University of New Jersesy | Inhibitors of bacterial RNA polymerase: arylpropanoyl, arylpropenoyl, and arylcyclopropanecarboxyl phloroglucinols |
| WO2017156458A1 (en) | 2016-03-11 | 2017-09-14 | University Of South Florida | Beta-lactamase inhibitors, formulations, and uses thereof |
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| DE4308451A1 (de) * | 1992-09-10 | 1994-04-14 | Bayer Ag | 3-Aryl-pyron-Derivate |
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1995
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