MX5097E - Procedimiento para preparar derivados del acido tiazolilacetico - Google Patents

Procedimiento para preparar derivados del acido tiazolilacetico

Info

Publication number
MX5097E
MX5097E MX752873U MX287375U MX5097E MX 5097 E MX5097 E MX 5097E MX 752873 U MX752873 U MX 752873U MX 287375 U MX287375 U MX 287375U MX 5097 E MX5097 E MX 5097E
Authority
MX
Mexico
Prior art keywords
procedure
preparing derivatives
thiazolylacetic acid
thiazolylacetic
acid
Prior art date
Application number
MX752873U
Other languages
English (en)
Inventor
Michihiko Ochiai
Osami Aki
Akina Marimoto
Taiiti Okada
Kenji Kawakita
Yoshihiro Matsushita
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26257200&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX5097(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from JP49146567A external-priority patent/JPS5760345B2/ja
Priority claimed from GB24611/75A external-priority patent/GB1536281A/en
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of MX5097E publication Critical patent/MX5097E/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/40—Unsubstituted amino or imino radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals
    • C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals
    • C07D277/48—Acylated amino or imino radicals by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof, e.g. carbonylguanidines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
MX752873U 1974-12-19 1975-12-17 Procedimiento para preparar derivados del acido tiazolilacetico MX5097E (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP49146567A JPS5760345B2 (es) 1974-12-19 1974-12-19
GB24611/75A GB1536281A (en) 1975-06-09 1975-06-09 Cephem compounds

Publications (1)

Publication Number Publication Date
MX5097E true MX5097E (es) 1983-03-16

Family

ID=26257200

Family Applications (1)

Application Number Title Priority Date Filing Date
MX752873U MX5097E (es) 1974-12-19 1975-12-17 Procedimiento para preparar derivados del acido tiazolilacetico

Country Status (18)

Country Link
US (6) US4098888A (es)
AT (1) AT357521B (es)
AU (1) AU500104B2 (es)
BE (1) BE836813A (es)
BG (1) BG60437B2 (es)
CA (3) CA1216284A (es)
CH (4) CH624119A5 (es)
DE (3) DE2560398C2 (es)
DK (2) DK154939C (es)
ES (4) ES443627A1 (es)
FR (4) FR2294690A1 (es)
GB (1) GB1536283A (es)
HU (1) HU179798B (es)
MX (1) MX5097E (es)
NL (4) NL183703C (es)
NO (1) NO157933C (es)
PH (2) PH13731A (es)
SE (2) SE442202B (es)

Families Citing this family (166)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4191762A (en) 1974-03-14 1980-03-04 Fujisawa Pharmaceutical Co., Ltd. 2-Lower alkyl-7-substituted amino-2 or 3-cephem-4-carboxylic acid compounds
US4297489A (en) * 1974-09-03 1981-10-27 Bristol-Myers Company 7-α-Amino-substituted acylamino-3-(1-carboxymethyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acids
US4182868A (en) * 1974-10-29 1980-01-08 Takeda Chemical Industries, Ltd. 7-Methoxycephalosporin derivatives
DK154939C (da) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
JPS5760345B2 (es) * 1974-12-19 1982-12-18 Takeda Chemical Industries Ltd
DE2760123C2 (de) 1976-01-23 1986-04-30 Roussel-Uclaf, Paris 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
US4196205A (en) * 1976-01-23 1980-04-01 Roussel Uclaf 3-Acetoxymethyl-7-(iminoacetamido)-cephalosporanic acid derivatives
SE440655B (sv) 1976-01-23 1985-08-12 Roussel Uclaf Sett att framstella nya oximderivat av 7-amino-tiazolyl-acetamido-cefalosporansyra
GB1575803A (en) 1976-03-09 1980-10-01 Fujisawa Pharmaceutical Co 3,7 disubstituted 3 cephem 4 carboxylic acid compounds andprocesses for the preparation thereof
IE44888B1 (en) * 1976-03-09 1982-05-05 Fujisawa Pharmaceutical Co 3,7-disubstituted-3-cephem-4-carboxylic acid compounds and processes for the preparation theroef
US4299829A (en) 1976-03-12 1981-11-10 Fujisawa Pharmaceutical Co., Ltd. 2-Lower alkyl-7-substituted-2 or 3-cephem 4-carboxylic acid compounds
US4202893A (en) 1976-03-25 1980-05-13 Roussel Uclaf Alkyloximes of 7-amino-thiazolyl-acetamido-cephalosporanic acids
FR2345153A1 (fr) * 1976-03-25 1977-10-21 Roussel Uclaf Nouvelles alcoyloximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
US4166115A (en) 1976-04-12 1979-08-28 Fujisawa Pharmaceutical Co., Ltd. Syn 7-oxoimino substituted derivatives of cephalosporanic acid
JPS5946237B2 (ja) * 1976-04-02 1984-11-10 武田薬品工業株式会社 セフアロスポリン誘導体およびその製造法
US4431643A (en) * 1976-04-12 1984-02-14 Fujisawa Pharmaceutical Co., Ltd. Syn-isomer of 3-substituted-7-[2-cyclopentyloxyimino-2-(2-aminothiazol-4-yl)-acetamido]-3
US4331664A (en) * 1976-04-12 1982-05-25 Fujisawa Pharmaceutical Co., Ltd. Syn isomer of 7-[2-cyclo(lower) alkoxyimino-2-(2-amino-or substituted aminothiazol-4-yl)acetamido]-3-lower alkanoyloxymethyl or heterocyclicthiomethyl-3-cephem-4-carboxylic acid compounds
US4804752A (en) * 1976-04-12 1989-02-14 Fujisawa Pharmaceutical Co., Ltd. Syn-isomer of 3,7-disubstituted-3-cephem-4-carboxylic acid compounds and processes for the preparation thereof
US4304770A (en) * 1976-04-12 1981-12-08 Fujisawa Pharmaceutical Co., Ltd. Syn-isomer of 3,7-disubstituted-3-cephem-4-carboxylic acid compounds and processes for the preparation thereof
US4364943A (en) * 1976-04-12 1982-12-21 Fujisawa Pharmaceutical Co., Ltd. Syn-isomer of 7-[2-alkoxyimino-2-(2-amino-alkanoylamino-or haloalkanoylamino-thiazol-4-yl) acetamids]-3-[hexanoyl-, or phenylalkanoyl-oxymethyl or benzothiazolylthiomethyl]-3-cephem-4-carboxylic acid
US4493833A (en) * 1976-04-12 1985-01-15 Fujisawa Pharmaceutical Co., Ltd. Syn-isomer of 3,7-disubstituted-3-cephem-4-carboxylic acid compounds
FR2367756B1 (fr) * 1976-04-12 1985-07-05 Fujisawa Pharmaceutical Co Derives 2-alcoxyamino-2-(amino-1,3-thiazolyl) acetiques et leur utilisation
DK162391C (da) * 1976-04-12 1992-03-09 Fujisawa Pharmaceutical Co Analogifremgangsmaade til fremstilling af syn-isomerer af 3,7-disubstituerede 3-cephem-4-carboxylsyreforbindelser
DE2715385A1 (de) * 1976-04-14 1977-11-10 Takeda Chemical Industries Ltd Cephalosporinderivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
DE2760488C2 (de) * 1976-04-14 1994-04-07 Takeda Chemical Industries Ltd Cephalosporinderivate, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel
DE2760482C2 (de) * 1976-04-14 1995-02-09 Takeda Chemical Industries Ltd Pharmazeutische Zubereitungen, enthaltend ein 7-[2-(2-aminothiazol-4yl)-2-(syn)-methoxyiminoacetamido]cephalosporinderivat
DE2760491C2 (de) * 1976-09-08 1995-04-20 Takeda Chemical Industries Ltd Pharmazeutische Zubereitungen enthaltend Pivaloyloxymethyl 7- 2-(2-aminothiazol-4-yl)-2-(syn)mehtoxyiminoacetamido desacetoxycephalosporanat und dessen Salze
FI771866A (es) * 1976-06-28 1977-12-29 Fujisawa Pharmaceutical Co
JPS6011713B2 (ja) 1976-09-08 1985-03-27 武田薬品工業株式会社 セフアロスポリン誘導体およびその製造法
US4963542A (en) * 1976-09-08 1990-10-16 Takeda Chemical Industries, Ltd. Cephalosporin derivatives
GB1592149A (en) * 1976-10-08 1981-07-01 Fujisawa Pharmaceutical Co 3 7-disubstituted-3-cephem-4-carboxylic acid compounds and processes for preparation thereof
NL7714319A (nl) * 1976-12-27 1978-06-29 Fujisawa Pharmaceutical Co Cefalosporineverbindingen en werkwijzen om deze te bereiden.
JPS53144594A (en) * 1976-12-27 1978-12-15 Fujisawa Pharmaceut Co Ltd 3,7-di-substitued-3-cephem-4-carboxylic acid derivatives
JPS53101393A (en) 1977-02-17 1978-09-04 Takeda Chem Ind Ltd Cephalosporin derivatives and process for their preparation
JPS6011714B2 (ja) 1977-02-17 1985-03-27 武田薬品工業株式会社 セフアロスポリン誘導体およびその製造法
FR2381053A1 (fr) * 1977-02-18 1978-09-15 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-thiadiazolyl thiomethyl 7-aminothiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
JPS53103493A (en) 1977-02-18 1978-09-08 Takeda Chem Ind Ltd Cephalosporin derivatives and process for their preparation
ES467601A1 (es) * 1977-03-12 1979-06-16 Hoechst Ag Procedimiento para la preparacion de derivados de cefem.
PH17188A (en) 1977-03-14 1984-06-14 Fujisawa Pharmaceutical Co New cephem and cepham compounds and their pharmaceutical compositions and method of use
US4841062A (en) * 1977-03-14 1989-06-20 Fujisawa Pharmaceutical Company, Limited New cephem and cepham compounds and processes for preparation thereof
SE439312B (sv) 1977-03-25 1985-06-10 Roussel Uclaf Sett att framstella nya oximderivat av 3-acetoximetyl-7-aminotiazolylacetamido cefalosporansyra
GB1579533A (en) * 1977-03-26 1980-11-19 Farmaceutici Italia Cephalosporins and their preparation
DE2714880A1 (de) * 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
DE2716677C2 (de) * 1977-04-15 1985-10-10 Hoechst Ag, 6230 Frankfurt Cephemderivate und Verfahren zu ihrer Herstellung
US5089490A (en) * 1977-04-02 1992-02-18 Hoechst Aktiengesellschaft Cephem derivatives
DE2857696C2 (de) * 1977-07-23 1984-08-30 Toyama Chemical Co. Ltd., Tokio / Tokyo Cephalosporine
JPS609719B2 (ja) * 1977-08-06 1985-03-12 武田薬品工業株式会社 セフアロスポリン誘導体およびその製造法
FR2400519A1 (fr) * 1977-08-17 1979-03-16 Roussel Uclaf Forme cristalline du sel de sodium d'un derive oximine de l'acide 7-amino-thiazolyl acetamido cephalosporanique, son procede de preparation et son application comme medicament
US4370326A (en) * 1977-09-13 1983-01-25 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds and composition
IT1192287B (it) * 1977-11-14 1988-03-31 Fujisawa Pharmaceutical Co Derivati di acido cefalosporanico ad azione farmaceutica e relativo procedimento di preparazione
FR2410655A1 (fr) * 1977-12-05 1979-06-29 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-substitue 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
DE2758001A1 (de) 1977-12-24 1979-07-12 Hoechst Ag Cephalosporinderivate und verfahren zu ihrer herstellung
FR2387235A1 (fr) * 1978-01-23 1978-11-10 Fujisawa Pharmaceutical Co Procede de preparation de composes d'acide 3,7-disubstitue-3-cephem-4-carboxylique et nouveaux produits ainsi obtenus, ayant une forte activite antibacterienne
JPS54112892A (en) * 1978-02-23 1979-09-04 Shionogi & Co Ltd Substituted imidazolidinyl-3-chloro-3-cephem-4-carboxylic acid
US4180658A (en) * 1978-02-24 1979-12-25 Bristol-Myers Company 7[-2-Alkoxyamino(acetamido)]cephalosporin derivatives
JPS54117494A (en) * 1978-03-03 1979-09-12 Takeda Chem Ind Ltd Cephalosporin compound and its preparation
FR2421907A1 (fr) * 1978-04-07 1979-11-02 Roussel Uclaf Nouvelles cephalosporines derivees de l'acide 7-/2-(2-amino 4-thiazolyl)2-(carboxymethoxyimino/acetamido 3-substitue cephalosporanique, leur procede de preparation et leur application comme medicaments
SE445350B (sv) * 1978-04-14 1986-06-16 Roussel Uclaf Oximderivat av 3-azidometyl-7-amino-tiazolyl-acetamido-cefalosporansyra och dess anvendning som antibiotika
DE2818263A1 (de) * 1978-04-26 1979-11-08 Bayer Ag Beta-lactamantibiotika
AR228726A1 (es) * 1978-05-26 1983-04-15 Glaxo Group Ltd Procedimiento para la preparacion del antibiotico(6r,7r)-7-((z)-2-(2-aminotiazol-4-il)-2-(2-carboxiprop-2-oxiimino)acetamido)-3-(1-piridiniometil)cef-3-em-4-carboxilato
CH641468A5 (de) * 1978-05-30 1984-02-29 Hoffmann La Roche Cephemderivate.
JPS54160392A (en) * 1978-06-02 1979-12-19 Takeda Chem Ind Ltd Cephalosporin derivative and its preparation
US4461767A (en) * 1978-06-16 1984-07-24 E. R. Squibb & Sons, Inc. Iminothiazolyl ureido cephalosporins
US4501743A (en) * 1978-06-16 1985-02-26 E. R. Squibb & Sons, Inc. Iminothiazolyl ureido cephalosporins
US4268509A (en) * 1978-07-10 1981-05-19 Fujisawa Pharmaceutical Co., Ltd. New cephem compounds and processes for preparation thereof
ATE15897T1 (de) * 1978-07-17 1985-10-15 Fujisawa Pharmaceutical Co Ausgangsprodukte zur herstellung von cephalosporinen und verfahren zu ihrer herstellung.
JPS6058239B2 (ja) * 1978-07-20 1985-12-19 山之内製薬株式会社 新規セフアロスポリン誘導体
US4372952A (en) * 1978-07-31 1983-02-08 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
US4284631A (en) * 1978-07-31 1981-08-18 Fujisawa Pharmaceutical Co., Ltd. 7-Substituted cephem compounds and pharmaceutical antibacterial compositions containing them
US4305937A (en) * 1978-08-17 1981-12-15 Fujisawa Pharmaceutical Co., Ltd. 2-Lower alkyl-7-substituted-2 or 3-cephem-4-carboxylic acid compounds and antibacterial pharmaceutical compositions containing them
US4703046A (en) * 1978-09-08 1987-10-27 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds and processes for preparation thereof
US4341775A (en) * 1978-09-11 1982-07-27 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
EP0009671B1 (en) * 1978-09-12 1984-06-13 Fujisawa Pharmaceutical Co., Ltd. Starting compounds for preparing cephem compounds and processes for their preparation
US4220761A (en) * 1978-09-12 1980-09-02 Fujisawa Pharmaceutical Co., Ltd. 7-[Substituted oximinoacetamido]-3-[hydroxy alkyltetrazolo]cephalosporin derivatives
US4327093A (en) * 1978-10-24 1982-04-27 Fujisawa Pharmaceutical Co., Ltd. 3,7-Disubstituted-2 or 3-cephem-4-carboxylic acid compounds
FR2439786A1 (fr) * 1978-10-27 1980-05-23 Glaxo Group Ltd Nouvelles cephalosporines, leur procede de preparation et leurs applications therapeutiques
NO793688L (no) * 1978-11-15 1980-05-19 Glaxo Group Ltd Fremgangsmaate ved fremstilling av cephalosporinderivater
US4313945A (en) * 1978-11-23 1982-02-02 Ciba-Geigy Corporation 7-Thiazolyl-acetamido-cephem derivatives with terminal aminocarboxylic acid grouping
JPS5579393A (en) * 1978-12-11 1980-06-14 Takeda Chem Ind Ltd Cephalosporin derivative and its preparation
AU536842B2 (en) * 1978-12-29 1984-05-24 Fujisawa Pharmaceutical Co., Ltd. Cephalosporin antibiotics
US4332798A (en) * 1978-12-29 1982-06-01 Fujisawa Pharmaceutical Co., Ltd. 7-Amino-thia-diazole oxyimino derivatives of cephem and cephem compounds
FR2445830A1 (fr) * 1979-01-05 1980-08-01 Roussel Uclaf Nouveaux derives de l'acide (4-thiazolyl) acetique procede de preparation
NZ193212A (en) * 1979-03-22 1982-12-07 Glaxo Group Ltd Cephalosporin antibiotics and pharmaceutical compsitions
US4237128A (en) * 1979-04-12 1980-12-02 E. R. Squibb & Sons, Inc. 7-[2-(2-Amino-4-thiazolyl)-2-[(1-carboxy-1,1-dialkyl)alkoxyimino]acetamido]cephem sulfoxides
DK222180A (da) * 1979-05-23 1980-11-24 Rhone Poulenc Ind Fremgangsmaade til fremstilling af 3-thiovinylcephalosporiner
FR2457296A1 (fr) * 1979-05-23 1980-12-19 Rhone Poulenc Ind Nouveaux derives de vinyl-3 cephalosporines et leur preparation
DE3064106D1 (en) * 1979-06-07 1983-08-18 Yamanouchi Pharma Co Ltd 7-(thiazolylpropionamido) cephalosporins, their preparation, and pharmaceutical compositions containing them
US4275062A (en) * 1979-09-19 1981-06-23 E. R. Squibb & Sons, Inc. Aminothiazolyl ureido sulfoxide cephalosporins
US4252951A (en) * 1979-10-09 1981-02-24 Eli Lilly And Company Isolation of syn-7-(2-amino-4-thiazolyl)-(methoxyimino)acetamido-3-acetoxymethyl-3-cephem-4-carboxylic acid
US4332800A (en) * 1979-10-12 1982-06-01 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
US4381299A (en) * 1980-03-07 1983-04-26 Fujisawa Pharmaceutical Co., Ltd. 7-Amino-thiadiazole oxyimino derivatives of cephem and cepham compounds
US4338313A (en) * 1979-10-12 1982-07-06 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
US4271157A (en) * 1980-02-28 1981-06-02 E. R. Squibb & Sons, Inc. Imidazole derivatives of 7-[(2-amino-4-thiazolyl)-oximino] cephalosporins
US4409215A (en) * 1979-11-19 1983-10-11 Fujisawa Pharmaceutical Co., Ltd. 7-Acylamino-3-substituted cephalosporanic acid derivatives and processes for the preparation thereof
US4409214A (en) * 1979-11-19 1983-10-11 Fujisawa Pharmaceutical, Co., Ltd. 7-Acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof
US5243043A (en) * 1980-02-18 1993-09-07 Roussel Uclaf Cephalosporins
DE3006888A1 (de) * 1980-02-23 1981-09-10 Hoechst Ag, 6000 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung
DE3007685A1 (de) 1980-02-29 1981-10-01 Dr. Karl Thomae Gmbh, 7950 Biberach Neue cephylosporine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US4252802A (en) * 1980-03-13 1981-02-24 E. R. Squibb & Sons, Inc. Hydroxamic acid derivatives of 7-[(2-amino-4-thiazolyl)-oximino] cephalosporins
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US4205180A (en) 1980-05-27
PH13731A (en) 1980-09-09
AU8766775A (en) 1977-06-23
NL7800731A (nl) 1978-05-31
BG60437B2 (bg) 1995-03-31
CH628058A5 (de) 1982-02-15
FR2468599A1 (fr) 1981-05-08
CA1216284A (en) 1987-01-06
DK154939C (da) 1989-06-12
FR2357552A1 (fr) 1978-02-03
ATA517277A (de) 1979-12-15
SE7902954L (sv) 1979-04-03
ES457891A1 (es) 1978-08-01
NL7514811A (nl) 1976-06-22
DE2556736C2 (de) 1982-02-11
US4973684A (en) 1990-11-27
AT357521B (de) 1980-07-10
FR2294690B1 (es) 1982-01-29
ES443627A1 (es) 1977-10-16
NO157933C (no) 1988-06-15
DK548875A (da) 1976-06-20
AU500104B2 (en) 1979-05-10
FR2434146A1 (fr) 1980-03-21
DK155086C (da) 1989-06-19
BE836813A (fr) 1976-06-18
DK155086B (da) 1989-02-06
US4912212A (en) 1990-03-27
FR2434146B1 (es) 1984-02-10
NL183703C (nl) 1989-01-02
ES464772A1 (es) 1979-01-01
NO157933B (no) 1988-03-07
DE2556736A1 (de) 1976-06-24
DK552377A (da) 1977-12-09
FR2468599B1 (fr) 1986-03-21
CA1128957A (en) 1982-08-03
US4098888A (en) 1978-07-04
SE445454B (sv) 1986-06-23
CH624119A5 (es) 1981-07-15
CH631437A5 (de) 1982-08-13
CH633544A5 (de) 1982-12-15
DK154939B (da) 1989-01-09
NO754296L (es) 1976-06-22
US4514565A (en) 1985-04-30
GB1536283A (en) 1978-12-20
NL8003054A (nl) 1980-08-29
US5583216A (en) 1996-12-10
CA1137492A (en) 1982-12-14
NL183703B (nl) 1988-08-01
FR2294690A1 (fr) 1976-07-16
ES464771A1 (es) 1978-09-01
PH14161A (en) 1981-03-19
HU179798B (en) 1982-12-28
SE442202B (sv) 1985-12-09
NL950016I1 (nl) 1996-03-01
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SE7514286L (sv) 1976-06-20
DE2559942C2 (de) 1985-02-28

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