MX2020000331A - Inhibidores de acetil coa carboxilasa (acc) y usos de los mismos. - Google Patents

Inhibidores de acetil coa carboxilasa (acc) y usos de los mismos.

Info

Publication number
MX2020000331A
MX2020000331A MX2020000331A MX2020000331A MX2020000331A MX 2020000331 A MX2020000331 A MX 2020000331A MX 2020000331 A MX2020000331 A MX 2020000331A MX 2020000331 A MX2020000331 A MX 2020000331A MX 2020000331 A MX2020000331 A MX 2020000331A
Authority
MX
Mexico
Prior art keywords
acc
plant
inhibitors
acc inhibitors
hyperiipidemia
Prior art date
Application number
MX2020000331A
Other languages
English (en)
Inventor
Geraldine C Harriman
Craig E Masse
James Harwood
Sathesh Bhat
Jeremy Robert Greenwood
Original Assignee
Gilead Apollo Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gilead Apollo Llc filed Critical Gilead Apollo Llc
Publication of MX2020000331A publication Critical patent/MX2020000331A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Abstract

La presente invención proporciona compuestos, específicamente derivados de tienopirimidina útiles como inhibidores de acetil CoA carboxilasa (ACC), composiciones farmacéuticas de los mismos y métodos de uso de los mismos para tratar trastornos mediados por ACC tales como obesidad, dislipidemia, hiperlipidemia, infecciones micóticas, parasitarias o bacterianas en un sujeto. La invención proporciona además un método para inhibir ACC en una planta que comprende poner en contacto a la planta con el compuesto inhibidor.
MX2020000331A 2011-11-11 2012-11-09 Inhibidores de acetil coa carboxilasa (acc) y usos de los mismos. MX2020000331A (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161559023P 2011-11-11 2011-11-11
US201261615092P 2012-03-23 2012-03-23
US201261651878P 2012-05-25 2012-05-25
US201261675513P 2012-07-25 2012-07-25
PCT/US2012/064528 WO2013071169A1 (en) 2011-11-11 2012-11-09 Acc inhibitors and uses thereof

Publications (1)

Publication Number Publication Date
MX2020000331A true MX2020000331A (es) 2022-03-16

Family

ID=48281206

Family Applications (3)

Application Number Title Priority Date Filing Date
MX2016016733A MX370976B (es) 2011-11-11 2012-11-09 Inhibidores de acetil coa carboxilasa (acc) y usos de los mismos.
MX2014005693A MX344490B (es) 2011-11-11 2012-11-09 Inhibidores de acetil coa carboxilasa (acc) y usos de los mismos.
MX2020000331A MX2020000331A (es) 2011-11-11 2012-11-09 Inhibidores de acetil coa carboxilasa (acc) y usos de los mismos.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
MX2016016733A MX370976B (es) 2011-11-11 2012-11-09 Inhibidores de acetil coa carboxilasa (acc) y usos de los mismos.
MX2014005693A MX344490B (es) 2011-11-11 2012-11-09 Inhibidores de acetil coa carboxilasa (acc) y usos de los mismos.

Country Status (26)

Country Link
US (5) US8969557B2 (es)
EP (3) EP3628320B1 (es)
JP (4) JP6114297B2 (es)
KR (3) KR102033806B1 (es)
CN (3) CN104105485B (es)
AU (3) AU2012335088B2 (es)
BR (2) BR112014011351B1 (es)
CA (1) CA2855372C (es)
CL (1) CL2014001241A1 (es)
CY (2) CY1120224T1 (es)
DK (2) DK2776038T3 (es)
EA (2) EA030264B1 (es)
ES (3) ES2912574T3 (es)
HK (1) HK1201207A1 (es)
HR (2) HRP20180534T1 (es)
HU (2) HUE037444T2 (es)
LT (2) LT3329919T (es)
MX (3) MX370976B (es)
PL (3) PL2776038T3 (es)
PT (2) PT3329919T (es)
RS (1) RS57157B1 (es)
SI (2) SI2776038T1 (es)
TW (4) TWI701253B (es)
UA (2) UA123760C2 (es)
WO (1) WO2013071169A1 (es)
ZA (3) ZA201403633B (es)

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JP2018052989A (ja) 2018-04-05
NZ624819A (en) 2016-10-28
TW201930310A (zh) 2019-08-01
ZA201403633B (en) 2021-10-27
ES2912574T3 (es) 2022-05-26
JP6756014B2 (ja) 2020-09-16
WO2013071169A1 (en) 2013-05-16
AU2019253834A1 (en) 2019-11-14
US20160297834A1 (en) 2016-10-13
HK1201207A1 (en) 2015-08-28
US10472374B2 (en) 2019-11-12
HRP20192202T1 (hr) 2020-03-06
CN106905346A (zh) 2017-06-30
EA201490826A1 (ru) 2015-01-30
CN106905346B (zh) 2019-05-28
MX344490B (es) 2016-12-16
US20130123231A1 (en) 2013-05-16
AU2012335088B2 (en) 2017-08-24
CN104105485A (zh) 2014-10-15
EP3329919A8 (en) 2020-10-07
NZ738735A (en) 2019-08-30
US20150203510A1 (en) 2015-07-23
PL3628320T3 (pl) 2022-07-25
TWI701253B (zh) 2020-08-11
JP2014533281A (ja) 2014-12-11
EP2776038A1 (en) 2014-09-17

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