BR112015028152A2 - inibidores de acc e usos dos mesmos - Google Patents
inibidores de acc e usos dos mesmosInfo
- Publication number
- BR112015028152A2 BR112015028152A2 BR112015028152A BR112015028152A BR112015028152A2 BR 112015028152 A2 BR112015028152 A2 BR 112015028152A2 BR 112015028152 A BR112015028152 A BR 112015028152A BR 112015028152 A BR112015028152 A BR 112015028152A BR 112015028152 A2 BR112015028152 A2 BR 112015028152A2
- Authority
- BR
- Brazil
- Prior art keywords
- acc
- inhibitors
- acc inhibitors
- compositions
- carboxylase
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
Abstract
abstract the present invention provides compounds useful as inhibitors of acetyl coa carboxylase (acc), compositions thereof, and methods of using the same. ___________________________________________________ resumo patente de invenção: "inibidores de acc e usos dos mesmos". a presente invenção fornece compostos úteis como inibidores de acetil coa carboxilase (acc), composições dos mesmos, e métodos de usar os mesmos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361821828P | 2013-05-10 | 2013-05-10 | |
PCT/US2014/037363 WO2014182945A1 (en) | 2013-05-10 | 2014-05-08 | Acc inhibitors and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112015028152A2 true BR112015028152A2 (pt) | 2017-07-25 |
Family
ID=51867753
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112015028152A BR112015028152A2 (pt) | 2013-05-10 | 2014-05-08 | inibidores de acc e usos dos mesmos |
Country Status (14)
Country | Link |
---|---|
US (1) | US10208063B2 (pt) |
EP (1) | EP2994139B1 (pt) |
JP (1) | JP6434498B2 (pt) |
KR (1) | KR20160006762A (pt) |
CN (1) | CN105358154A (pt) |
AR (1) | AR096242A1 (pt) |
AU (1) | AU2014262638A1 (pt) |
BR (1) | BR112015028152A2 (pt) |
CA (1) | CA2911932A1 (pt) |
CL (1) | CL2015003315A1 (pt) |
EA (1) | EA030942B1 (pt) |
HK (2) | HK1221411A1 (pt) |
MX (1) | MX2015015422A (pt) |
WO (1) | WO2014182945A1 (pt) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2911822A1 (en) | 2013-05-10 | 2014-11-13 | Nimbus Apollo, Inc. | Acc inhibitors and uses thereof |
CN105358152A (zh) | 2013-05-10 | 2016-02-24 | 尼普斯阿波罗有限公司 | Acc抑制剂和其用途 |
JP6417402B2 (ja) | 2013-05-10 | 2018-11-07 | ギリアド アポロ, エルエルシー | Acc阻害剤及びその使用 |
EP3670496A3 (en) | 2013-10-17 | 2020-09-30 | Shionogi&Co., Ltd. | Acc2 inhibitors |
WO2016084816A1 (ja) * | 2014-11-26 | 2016-06-02 | 武田薬品工業株式会社 | 二環性化合物 |
EP3242722A4 (en) | 2015-01-09 | 2018-07-11 | Gilead Apollo, LLC | Acc inhibitor combination therapy for the treatment of non-alcoholic fatty liver disease |
AR106472A1 (es) | 2015-10-26 | 2018-01-17 | Gilead Apollo Llc | Inhibidores de acc y usos de los mismos |
EA201890910A1 (ru) | 2015-11-25 | 2018-11-30 | Джилид Аполло, Ллс | ФУНГИЦИДНЫЕ КОМПОЗИЦИИ, СОДЕРЖАЩИЕ ПРОИЗВОДНЫЕ 2,4-ДИОКСО-1,4-ДИГИДРОТИЕНО[2,3-d]ПИРИМИДИНА |
EA201890913A1 (ru) | 2015-11-25 | 2018-11-30 | Джилид Аполло, Ллс | Пиразоловые соединения в качестве ингибиторов акк и их применение |
SI3380479T1 (sl) | 2015-11-25 | 2023-04-28 | Gilead Apollo, Llc | Triazolni inhibitorji ACC in uporabe le-teh |
EA201890949A1 (ru) | 2015-11-25 | 2018-12-28 | Джилид Аполло, Ллс | СЛОЖНОЭФИРНЫЕ ИНГИБИТОРЫ АЦЕТИЛ-КоА-КАРБОКСИЛАЗЫ И ВАРИАНТЫ ИХ ПРИМЕНЕНИЯ |
US11142531B2 (en) | 2017-03-24 | 2021-10-12 | Zhejiang Hisun Pharmaceutical Co., Ltd. | Cyano substituted heteroarylpyrimidinone derivative, preparation method and use thereof |
CN110431143B (zh) * | 2017-03-24 | 2022-08-12 | 浙江海正药业股份有限公司 | 杂芳基并嘧啶酮类衍生物及其制备方法和用途 |
KR20210114457A (ko) | 2019-01-15 | 2021-09-23 | 길리애드 사이언시즈, 인코포레이티드 | Fxr (nr1h4) 조정 화합물 |
AR119594A1 (es) | 2019-08-09 | 2021-12-29 | Gilead Sciences Inc | Derivados de tienopirimidina como inhibidores acc y usos de los mismos |
AU2020384883B2 (en) | 2019-11-15 | 2023-11-16 | Gilead Sciences, Inc. | Triazole carbamate pyridyl sulfonamides as LPA receptor antagonists and uses thereof |
US11578081B1 (en) | 2019-12-05 | 2023-02-14 | Zhangzhou Pien Tze Huang Pharmaceutical Co., Ltd. | Crystal form as inhibitor of ACC1 and ACC2, and preparation method therefor and use thereof |
CN114787166B (zh) * | 2019-12-05 | 2023-09-19 | 漳州片仔癀药业股份有限公司 | 噻吩并[2,3-c]哒嗪-4(1H)-酮类化合物的晶型及其制备方法和应用 |
US11478533B2 (en) | 2020-04-27 | 2022-10-25 | Novo Nordisk A/S | Semaglutide for use in medicine |
CN115867556A (zh) | 2020-06-03 | 2023-03-28 | 吉利德科学公司 | Lpa受体拮抗剂及其用途 |
TW202344504A (zh) | 2020-06-03 | 2023-11-16 | 美商基利科學股份有限公司 | Lpa受體拮抗劑及其用途 |
US20220411405A1 (en) | 2021-05-11 | 2022-12-29 | Gilead Sciences, Inc. | Lpa receptor antagonists and uses thereof |
CA3218569A1 (en) | 2021-05-13 | 2022-11-17 | Gilead Sciences, Inc. | Lpa receptor antagonists and uses thereof |
WO2023107938A1 (en) | 2021-12-08 | 2023-06-15 | Gilead Sciences, Inc. | Lpa receptor antagonists and uses thereof |
CN116267361A (zh) * | 2023-05-10 | 2023-06-23 | 沈阳农业大学 | 一种防治十字花科作物根肿病的方法 |
Family Cites Families (105)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3060084A (en) | 1961-06-09 | 1962-10-23 | Du Pont | Improved homogeneous, readily dispersed, pesticidal concentrate |
US3299566A (en) | 1964-06-01 | 1967-01-24 | Olin Mathieson | Water soluble film containing agricultural chemicals |
US3325503A (en) | 1965-02-18 | 1967-06-13 | Diamond Alkali Co | Polychloro derivatives of mono- and dicyano pyridines and a method for their preparation |
US3296272A (en) | 1965-04-01 | 1967-01-03 | Dow Chemical Co | Sulfinyl- and sulfonylpyridines |
FR1453897A (fr) | 1965-06-16 | 1966-07-22 | Dérivés du thiophène et de thiéno pyridazines | |
US4144050A (en) | 1969-02-05 | 1979-03-13 | Hoechst Aktiengesellschaft | Micro granules for pesticides and process for their manufacture |
US3920442A (en) | 1972-09-18 | 1975-11-18 | Du Pont | Water-dispersible pesticide aggregates |
US4172714A (en) | 1976-12-20 | 1979-10-30 | E. I. Du Pont De Nemours And Company | Dry compactible, swellable herbicidal compositions and pellets produced therefrom |
GB2095558B (en) | 1981-03-30 | 1984-10-24 | Avon Packers Ltd | Formulation of agricultural chemicals |
US5304732A (en) | 1984-03-06 | 1994-04-19 | Mgi Pharma, Inc. | Herbicide resistance in plants |
GB8524663D0 (en) | 1985-10-07 | 1985-11-13 | Fujisawa Pharmaceutical Co | Quinazoline derivatives |
FR2629098B1 (fr) | 1988-03-23 | 1990-08-10 | Rhone Poulenc Agrochimie | Gene chimerique de resistance herbicide |
US5180587A (en) | 1988-06-28 | 1993-01-19 | E. I. Du Pont De Nemours And Company | Tablet formulations of pesticides |
ATE241699T1 (de) | 1989-03-24 | 2003-06-15 | Syngenta Participations Ag | Krankheitsresistente transgene pflanze |
EP0415688B1 (en) | 1989-08-30 | 1998-12-23 | Aeci Ltd | Dosage device and use thereof |
JPH0747582B2 (ja) | 1989-12-11 | 1995-05-24 | 杏林製薬株式会社 | キナゾリン―3―アルカン酸誘導体とその塩およびその製造法 |
PL167613B1 (pl) | 1990-03-12 | 1995-09-30 | Du Pont | Granulowana kompozycja rozpuszczalna lub dyspergowalna w wodzie PL |
DE69132939T2 (de) | 1990-06-25 | 2002-11-14 | Monsanto Technology Llc | Glyphosattolerante pflanzen |
EP0480679B1 (en) | 1990-10-11 | 1996-09-18 | Sumitomo Chemical Company Limited | Pesticidal composition |
UA48104C2 (uk) | 1991-10-04 | 2002-08-15 | Новартіс Аг | Фрагмент днк, який містить послідовність,що кодує інсектицидний протеїн, оптимізовану для кукурудзи,фрагмент днк, який забезпечує направлену бажану для серцевини стебла експресію зв'язаного з нею структурного гена в рослині, фрагмент днк, який забезпечує специфічну для пилку експресію зв`язаного з нею структурного гена в рослині, рекомбінантна молекула днк, спосіб одержання оптимізованої для кукурудзи кодуючої послідовності інсектицидного протеїну, спосіб захисту рослин кукурудзи щонайменше від однієї комахи-шкідника |
US6069298A (en) | 1993-02-05 | 2000-05-30 | Regents Of The University Of Minnesota | Methods and an acetyl CoA carboxylase gene for conferring herbicide tolerance and an alteration in oil content of plants |
US6303181B1 (en) | 1993-05-17 | 2001-10-16 | Electrochemicals Inc. | Direct metallization process employing a cationic conditioner and a binder |
US5530195A (en) | 1994-06-10 | 1996-06-25 | Ciba-Geigy Corporation | Bacillus thuringiensis gene encoding a toxin active against insects |
US5773704A (en) | 1996-04-29 | 1998-06-30 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Herbicide resistant rice |
US5773702A (en) | 1996-07-17 | 1998-06-30 | Board Of Trustees Operating Michigan State University | Imidazolinone herbicide resistant sugar beet plants |
AU3596697A (en) | 1996-07-17 | 1998-02-09 | Michigan State University | Imidazolinone herbicide resistant sugar beet plants |
DE19650197A1 (de) | 1996-12-04 | 1998-06-10 | Bayer Ag | 3-Thiocarbamoylpyrazol-Derivate |
TW460476B (en) | 1997-04-14 | 2001-10-21 | American Cyanamid Co | Fungicidal trifluoromethylalkylamino-triazolopyrimidines |
DK1017670T3 (da) | 1997-09-18 | 2002-12-16 | Basf Ag | Benzamidoximderivater, mellemprodukter og fremgangsmåder til deres fremstilling og deres anvendelse som fungicider |
DE19750012A1 (de) | 1997-11-12 | 1999-05-20 | Bayer Ag | Isothiazolcarbonsäureamide |
WO1999027783A1 (en) | 1997-12-04 | 1999-06-10 | Dow Agrosciences Llc | Fungicidal compositions and methods, and compounds and methods for the preparation thereof |
GB9817623D0 (en) | 1998-08-13 | 1998-10-07 | Glaxo Group Ltd | Pharmaceutical compounds |
US6348643B1 (en) | 1998-10-29 | 2002-02-19 | American Cyanamid Company | DNA sequences encoding the arabidopsis acetohydroxy-acid synthase small subunit and methods of use |
CA2350968C (en) | 1998-11-17 | 2008-10-28 | Kumiai Chemical Industry Co., Ltd | Pyrimidinylbenzimidazole and triazinylbenzimidazole derivatives and agricultural/horticultural fungicide |
JP3417862B2 (ja) | 1999-02-02 | 2003-06-16 | 新東工業株式会社 | 酸化チタン光触媒高担持シリカゲルおよびその製造方法 |
US6586617B1 (en) | 1999-04-28 | 2003-07-01 | Sumitomo Chemical Takeda Agro Company, Limited | Sulfonamide derivatives |
DE10021412A1 (de) | 1999-12-13 | 2001-06-21 | Bayer Ag | Fungizide Wirkstoffkombinationen |
JP4880161B2 (ja) | 2000-01-25 | 2012-02-22 | シンジェンタ パーティシペーションズ アクチェンゲゼルシャフト | 除草製剤 |
US6376548B1 (en) | 2000-01-28 | 2002-04-23 | Rohm And Haas Company | Enhanced propertied pesticides |
BR0110410A (pt) | 2000-04-28 | 2003-07-01 | Basf Ag | Uso do gene ahas 2 mutante x112 de milho e herbicidas de imidazolinona para seleção de mudas transgênicas de monocotiledÈneas de milho, arroz e trigo resistentes aos herbicidas de imidazolinona |
EP1311162B1 (en) | 2000-08-25 | 2005-06-01 | Syngenta Participations AG | Bacillus thurigiensis crystal protein hybrids |
EP1322614A2 (en) | 2000-09-18 | 2003-07-02 | E. I. du Pont de Nemours and Company | Pyridinyl amides and imides for use as fungicides |
US6815556B2 (en) | 2000-11-17 | 2004-11-09 | Dow Agrosciences Llc | Compounds having fungicidal activity and processes to make and use same |
US6548738B2 (en) | 2000-12-26 | 2003-04-15 | Research Development Foundation | ACC2-knockout mice and uses thereof |
JP5034142B2 (ja) | 2001-04-20 | 2012-09-26 | 住友化学株式会社 | 植物病害防除剤組成物 |
DE10136065A1 (de) | 2001-07-25 | 2003-02-13 | Bayer Cropscience Ag | Pyrazolylcarboxanilide |
FR2828196A1 (fr) | 2001-08-03 | 2003-02-07 | Aventis Cropscience Sa | Derives de chromone a action fongicide, procede de preparation et application dans le domaine de l'agriculture |
MXPA04000962A (es) | 2001-08-09 | 2005-02-17 | Univ Saskatchewan | Plantas de trigo que tienen resistencia incrementada a los herbicidas de imidazolinona. |
RU2337531C2 (ru) | 2001-08-09 | 2008-11-10 | Юниверсити Оф Саскачеван | Растения пшеницы с повышенной устойчивостью к имидазолиноновым гербицидам |
CA2455512C (en) | 2001-08-09 | 2013-05-14 | Northwest Plant Breeding Company | Wheat plants having increased resistance to imidazolinone herbicides |
JPWO2003016286A1 (ja) | 2001-08-17 | 2004-12-02 | 三共アグロ株式会社 | 3−フェノキシ−4−ピリダジノール誘導体及びそれを含有する除草剤組成物 |
US7230167B2 (en) | 2001-08-31 | 2007-06-12 | Syngenta Participations Ag | Modified Cry3A toxins and nucleic acid sequences coding therefor |
US7304070B2 (en) | 2001-11-09 | 2007-12-04 | Cv Therapeutics, Inc. | A2B adenosine receptor antagonists |
US6977300B2 (en) | 2001-11-09 | 2005-12-20 | Cv Therapeutics, Inc. | A2B adenosine receptor antagonists |
AR037856A1 (es) | 2001-12-17 | 2004-12-09 | Syngenta Participations Ag | Evento de maiz |
AU2002354251A1 (en) | 2001-12-21 | 2003-07-09 | Nissan Chemical Industries, Ltd. | Bactericidal composition |
TWI327462B (en) | 2002-01-18 | 2010-07-21 | Sumitomo Chemical Co | Condensed heterocyclic sulfonyl urea compound, a herbicide containing the same, and a method for weed control using the same |
DE10204390A1 (de) | 2002-02-04 | 2003-08-14 | Bayer Cropscience Ag | Disubstituierte Thiazolylcarboxanilide |
WO2003074491A1 (en) | 2002-03-05 | 2003-09-12 | Syngenta Participations Ag | O-cyclopropyl-carboxanilides and their use as fungicides |
KR100985160B1 (ko) | 2002-06-06 | 2010-10-05 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 신규한 축합된 이미다졸 유도체 |
US7829762B2 (en) | 2002-07-10 | 2010-11-09 | Department Of Agriculture | Wheat plants having increased resistance to imidazolinone herbicides |
GB0227966D0 (en) | 2002-11-29 | 2003-01-08 | Syngenta Participations Ag | Organic Compounds |
ATE425668T1 (de) | 2003-01-06 | 2009-04-15 | Yissum Res Dev Co | Pflanzliche acetyl-coa carboxylase-hemmende herbizide als pestizide |
WO2004083193A1 (ja) | 2003-03-17 | 2004-09-30 | Sumitomo Chemical Company, Limited | アミド化合物およびこれを含有する殺菌剤組成物 |
US7423031B2 (en) | 2003-05-01 | 2008-09-09 | Irm Llc | Compounds and compositions as protein kinase inhibitors |
MXPA05012733A (es) | 2003-05-28 | 2006-05-17 | Basf Ag | Plantas de trigo que tienen tolerancia incrementada a los herbicidas de imidazolinona. |
EP1663466B1 (en) | 2003-06-23 | 2017-10-11 | Pioneer Hi-Bred International Inc. | Engineering single-gene-controlled staygreen potential into plants |
MXPA06002155A (es) | 2003-08-29 | 2007-01-25 | Inst Nac De Technologia Agrope | Plantas de arroz que tienen una tolerancia incrementada a los herbicidas de imidazolinona. |
TWI355894B (en) | 2003-12-19 | 2012-01-11 | Du Pont | Herbicidal pyrimidines |
PL1725561T3 (pl) | 2004-03-10 | 2010-12-31 | Basf Se | 5,6-Dialkilo-7-aminotriazolopirymidyny, sposób ich wytwarzania i ich zastosowanie do zwalczania szkodliwych grzybów oraz środki zawierające te związki |
CN1930165A (zh) | 2004-03-10 | 2007-03-14 | 巴斯福股份公司 | 5,6-二烷基-7-氨基三唑并嘧啶、其制备方法、在防治致病性真菌中的用途以及包含所述化合物的试剂 |
WO2005120234A2 (en) | 2004-06-03 | 2005-12-22 | E.I. Dupont De Nemours And Company | Fungicidal mixtures of amidinylphenyl compounds |
PE20060096A1 (es) | 2004-06-18 | 2006-03-16 | Basf Ag | (orto-fenil)-anilidas de acido 1-metil-3-difluorometil-pirazol-4-carboxilico como agentes fungicidas |
JP2008502625A (ja) | 2004-06-18 | 2008-01-31 | ビーエーエスエフ アクチェンゲゼルシャフト | N−(オルト−フェニル)−1−メチル−3−トリフルオロメチルピラゾール−4−カルボキシアニリドおよびそれらの殺菌剤としての使用 |
US7947691B2 (en) | 2004-07-21 | 2011-05-24 | Athersys, Inc. | Cyclic n-hydroxy imides as inhibitors of flap endonuclease and uses thereof |
GB0418048D0 (en) | 2004-08-12 | 2004-09-15 | Syngenta Participations Ag | Method for protecting useful plants or plant propagation material |
JP2006131559A (ja) * | 2004-11-05 | 2006-05-25 | Takeda Chem Ind Ltd | 含窒素複素環化合物 |
US20080262000A1 (en) | 2005-02-16 | 2008-10-23 | Basf Aktiengesellschaft | 5-Alkoxyalkyl-6-alkyl-7-Aminoazolopyrimidines, Process for Their Preparation, Their Use for Controlling Harmful Fungi, and Compositions Comprising Them |
DE102005007160A1 (de) | 2005-02-16 | 2006-08-24 | Basf Ag | Pyrazolcarbonsäureanilide, Verfahren zu ihrer Herstellung und sie enthaltende Mittel zur Bekämpfung von Schadpilzen |
DE102005009458A1 (de) | 2005-03-02 | 2006-09-07 | Bayer Cropscience Ag | Pyrazolylcarboxanilide |
KR20080034993A (ko) | 2005-08-10 | 2008-04-22 | 스미스클라인 비참 코포레이션 | 선택적 hm74a 작동제로서의 크산틴 유도체 |
KR101350071B1 (ko) | 2006-01-13 | 2014-01-14 | 다우 아그로사이언시즈 엘엘씨 | 6-(다-치환 아릴)-4-아미노피콜리네이트 및 그의제초제로서의 용도 |
EP1983832A2 (en) | 2006-02-09 | 2008-10-29 | Syngeta Participations AG | A method of protecting a plant propagation material, a plant, and/or plant organs |
WO2007095603A2 (en) | 2006-02-15 | 2007-08-23 | Abbott Laboratories | Novel acetyl-coa carboxylase (acc) inhibitors and their use in diabetes, obesity and metabolic syndrome |
WO2007103776A2 (en) | 2006-03-02 | 2007-09-13 | Cv Therapeutics, Inc. | A2a adenosine receptor antagonists |
BRPI0713836A2 (pt) | 2006-07-25 | 2013-05-28 | Cephalon Inc | composto, composiÇço farmacÊutica e mÉtodo para tratar distérbio |
TW200823225A (en) * | 2006-11-01 | 2008-06-01 | Astrazeneca Ab | New compounds |
PE20081559A1 (es) | 2007-01-12 | 2008-11-20 | Merck & Co Inc | DERIVADOS DE ESPIROCROMANONA SUSTITUIDOS COMO INHIBIDORES DE ACETIL CoA CARBOXILASA |
US20080200461A1 (en) | 2007-02-20 | 2008-08-21 | Cropsolution, Inc. | Modulators of acetyl-coenzyme a carboxylase and methods of use thereof |
NZ581419A (en) | 2007-05-25 | 2012-05-25 | Vertex Pharma | Modulators of cystic fibrosis transmembrane conductance regulator |
CN101481380B (zh) | 2008-01-08 | 2012-10-17 | 浙江医药股份有限公司新昌制药厂 | 噻吩并哒嗪类化合物及其制备方法、药物组合物及其用途 |
JP5592360B2 (ja) | 2008-07-02 | 2014-09-17 | アベキサ・リミテッド | イミダゾピリミジノンおよびその使用 |
US20110244059A1 (en) * | 2008-08-20 | 2011-10-06 | The University Of Medicine And Dentistry Of New Jersey | Inhibiting obesity progression by inhibiting adipocyte differentiation with a pre-adipocyte autophagy inhibitor |
WO2010050445A1 (ja) * | 2008-10-27 | 2010-05-06 | 武田薬品工業株式会社 | 二環性化合物 |
US20100113473A1 (en) * | 2008-10-30 | 2010-05-06 | Player Mark R | Aryl amide compound as an acetyl coenzyme a carboxylase inhibitor |
WO2010127212A1 (en) | 2009-04-30 | 2010-11-04 | Forest Laboratories Holdings Limited | Inhibitors of acetyl-coa carboxylase |
US8697739B2 (en) * | 2010-07-29 | 2014-04-15 | Novartis Ag | Bicyclic acetyl-CoA carboxylase inhibitors and uses thereof |
AR084032A1 (es) * | 2010-11-30 | 2013-04-17 | Takeda Pharmaceutical | Compuesto biciclico |
CN106117205B (zh) | 2011-04-22 | 2018-09-21 | 辉瑞大药厂 | 用作乙酰辅酶a羧化酶抑制剂类的吡唑并螺酮衍生物 |
JPWO2013035827A1 (ja) | 2011-09-09 | 2015-03-23 | 塩野義製薬株式会社 | 新規オレフィン誘導体 |
US20130116241A1 (en) | 2011-11-09 | 2013-05-09 | Abbvie Inc. | Novel inhibitor compounds of phosphodiesterase type 10a |
EA030264B1 (ru) | 2011-11-11 | 2018-07-31 | Джилид Аполло, Ллс | Ингибиторы асс и их применения |
CA2911822A1 (en) | 2013-05-10 | 2014-11-13 | Nimbus Apollo, Inc. | Acc inhibitors and uses thereof |
JP6417402B2 (ja) | 2013-05-10 | 2018-11-07 | ギリアド アポロ, エルエルシー | Acc阻害剤及びその使用 |
CN105358152A (zh) | 2013-05-10 | 2016-02-24 | 尼普斯阿波罗有限公司 | Acc抑制剂和其用途 |
-
2014
- 2014-05-08 EA EA201591960A patent/EA030942B1/ru not_active IP Right Cessation
- 2014-05-08 KR KR1020157035039A patent/KR20160006762A/ko not_active Application Discontinuation
- 2014-05-08 BR BR112015028152A patent/BR112015028152A2/pt not_active Application Discontinuation
- 2014-05-08 AU AU2014262638A patent/AU2014262638A1/en not_active Abandoned
- 2014-05-08 CA CA2911932A patent/CA2911932A1/en not_active Abandoned
- 2014-05-08 US US14/890,320 patent/US10208063B2/en active Active
- 2014-05-08 EP EP14794757.6A patent/EP2994139B1/en not_active Not-in-force
- 2014-05-08 WO PCT/US2014/037363 patent/WO2014182945A1/en active Application Filing
- 2014-05-08 JP JP2016513083A patent/JP6434498B2/ja active Active
- 2014-05-08 MX MX2015015422A patent/MX2015015422A/es unknown
- 2014-05-08 CN CN201480036127.7A patent/CN105358154A/zh active Pending
- 2014-05-09 AR ARP140101889A patent/AR096242A1/es unknown
-
2015
- 2015-11-10 CL CL2015003315A patent/CL2015003315A1/es unknown
-
2016
- 2016-08-11 HK HK16109587.2A patent/HK1221411A1/zh unknown
- 2016-08-18 HK HK16109919.1A patent/HK1221661A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
EP2994139A4 (en) | 2016-11-30 |
HK1221661A1 (zh) | 2017-06-09 |
US20160108061A1 (en) | 2016-04-21 |
EP2994139A1 (en) | 2016-03-16 |
EA201591960A1 (ru) | 2016-06-30 |
MX2015015422A (es) | 2016-06-21 |
CN105358154A (zh) | 2016-02-24 |
JP6434498B2 (ja) | 2018-12-05 |
CL2015003315A1 (es) | 2016-07-15 |
AR096242A1 (es) | 2015-12-16 |
WO2014182945A1 (en) | 2014-11-13 |
AU2014262638A1 (en) | 2015-11-26 |
KR20160006762A (ko) | 2016-01-19 |
US10208063B2 (en) | 2019-02-19 |
JP2016520063A (ja) | 2016-07-11 |
EA030942B1 (ru) | 2018-10-31 |
CA2911932A1 (en) | 2014-11-13 |
EP2994139B1 (en) | 2019-04-10 |
HK1221411A1 (zh) | 2017-06-02 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR112015028152A2 (pt) | inibidores de acc e usos dos mesmos | |
BR112015028173A2 (pt) | inibidores de acc e usos dos mesmos | |
BR112015028171A8 (pt) | Inibidores de acc e seu uso | |
BR112014017021A8 (pt) | inibidores de irak e usos dos mesmos | |
CO2018005381A2 (es) | Inhibidores éster de acc y usos de los mismos | |
BR112014011351A2 (pt) | inibidores de acc e usos dos mesmos | |
EA201890749A1 (ru) | ИНГИБИТОРЫ АЦЕТИЛ-КоА-КАРБОКСИЛАЗЫ (ACC) И ИХ ПРИМЕНЕНИЕ | |
BR112016006319A2 (pt) | inibidores de irak e usos dos mesmos | |
BR112018067408A2 (pt) | formas sólidas de um inibidor de acc de tienopirimidinadiona e métodos para a produção das mesmas | |
BR112018003343A2 (pt) | compostos heteroarila como inibidores de irak e usos dos mesmos | |
EA201591962A1 (ru) | Ингибиторы акк и их применение | |
BR112015000561A2 (pt) | inibidores de irak e usos dos mesmos | |
DOP2017000078A (es) | Indazoles sustituidos con bencilo como inhibidores de bub1. | |
EA201690473A1 (ru) | Комбинированный состав двух противовирусных соединений | |
BR112018003812A2 (pt) | compostos de heteroarila como inibidores de irak e usos dos mesmos | |
BR112015022191A8 (pt) | compostos heteroarila e usos dos mesmos | |
BR112018016433A2 (pt) | inibidores de heteroarila de pad4 | |
CR20150462A (es) | Inhibidores de erk y sus usos | |
BR112017002053A2 (pt) | composto de acordo com a fórmula (i), composição farmacêutica, e usos de um composto | |
EA201490806A1 (ru) | Комбинированный состав двух противовирусных соединений | |
BR112016001977A2 (pt) | septo acústico de vários segmentos | |
BR112017009800A2 (pt) | compostos de heteroarila como inibidores de irak e uso dos mesmos | |
EA201690598A1 (ru) | Аминогетероарил бензамиды в качестве ингибиторов киназы | |
BR112017005266A2 (pt) | inibidores de mk2 e uso dos mesmos | |
BR112014030655A8 (pt) | Compostos inibidores de pirimidinil tirosina quinase, e composição farmacêutica que os compreende |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B25D | Requested change of name of applicant approved |
Owner name: GILEAD APOLLO, INC. (US) |
|
B25D | Requested change of name of applicant approved |
Owner name: GILEAD APOLLO, LLC (US) |
|
B25G | Requested change of headquarter approved |
Owner name: GILEAD APOLLO, LLC (US) |
|
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B07E | Notice of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements | ||
B350 | Update of information on the portal [chapter 15.35 patent gazette] |