MEP2308A - Postupak za pripremanje citaloprama - Google Patents

Postupak za pripremanje citaloprama

Info

Publication number
MEP2308A
MEP2308A MEP-23/08A MEP2308A MEP2308A ME P2308 A MEP2308 A ME P2308A ME P2308 A MEP2308 A ME P2308A ME P2308 A MEP2308 A ME P2308A
Authority
ME
Montenegro
Prior art keywords
citalopram
preparation
compound
formula
fluorophenyl
Prior art date
Application number
MEP-23/08A
Other languages
Bosnian (bs)
English (en)
Inventor
Hans Petersen
Haleh Ahmadian
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of MEP2308A publication Critical patent/MEP2308A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Steroid Compounds (AREA)
  • Furan Compounds (AREA)
MEP-23/08A 2000-08-18 2001-08-14 Postupak za pripremanje citaloprama MEP2308A (xx)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200001231 2000-08-18
PCT/DK2001/000541 WO2002016341A1 (en) 2000-08-18 2001-08-14 Method for the preparation of citalopram

Publications (1)

Publication Number Publication Date
MEP2308A true MEP2308A (xx) 2010-02-10

Family

ID=8159660

Family Applications (2)

Application Number Title Priority Date Filing Date
MEP-23/08A MEP2308A (xx) 2000-08-18 2001-08-14 Postupak za pripremanje citaloprama
MEP-22/08A MEP2208A (xx) 2000-08-18 2001-08-14 Postupak za pripremanje citaloprama

Family Applications After (1)

Application Number Title Priority Date Filing Date
MEP-22/08A MEP2208A (xx) 2000-08-18 2001-08-14 Postupak za pripremanje citaloprama

Country Status (41)

Country Link
US (2) US6426422B1 (es)
EP (2) EP1309581B1 (es)
JP (2) JP2004506729A (es)
KR (2) KR100887207B1 (es)
CN (3) CN1239490C (es)
AR (3) AR029597A1 (es)
AT (4) ATE281447T1 (es)
AU (6) AU2001279608B2 (es)
BE (2) BE1013443A6 (es)
BG (2) BG65965B1 (es)
CA (2) CA2354877C (es)
CH (2) CH691969A5 (es)
CL (2) CL2008002412A1 (es)
CZ (2) CZ294746B6 (es)
DE (4) DE60106933T2 (es)
DK (4) DK1309581T3 (es)
EA (2) EA005946B1 (es)
ES (4) ES2228920T3 (es)
FI (2) FI20011621A (es)
FR (2) FR2813077B1 (es)
GB (2) GB2362647B (es)
GR (1) GR1004074B (es)
HK (3) HK1044538B (es)
HR (2) HRP20030065A2 (es)
HU (2) HUP0103291A3 (es)
IE (2) IES20010761A2 (es)
IL (2) IL144816A (es)
IS (2) IS2120B (es)
ME (2) MEP2308A (es)
MX (2) MXPA03000913A (es)
NL (2) NL1018776C1 (es)
NO (2) NO326570B1 (es)
NZ (2) NZ523853A (es)
PL (2) PL359825A1 (es)
PT (2) PT1309581E (es)
RS (2) RS50258B (es)
SI (2) SI1309581T1 (es)
SK (2) SK287008B6 (es)
UA (2) UA71676C2 (es)
WO (2) WO2002016342A1 (es)
ZA (1) ZA200106683B (es)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR022329A1 (es) 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
NZ514671A (en) 1999-04-14 2003-10-31 H Method for the preparation of citalopram
ITMI991581A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
DK1228056T3 (da) 1999-10-25 2005-01-24 Lundbeck & Co As H Fremgangsmåde til fremstilling af citalopram
AR026063A1 (es) 1999-11-01 2002-12-26 Lundbeck & Co As H Metodo para la preparacion de 5-carboxiftalida.
JP2003519136A (ja) 1999-12-28 2003-06-17 ハー・ルンドベック・アクチエゼルスカベット シタロプラムの製造方法
DE69912652T2 (de) 1999-12-30 2004-06-09 H. Lundbeck A/S Verfahren zur herstellung von citalopram
SI1254129T1 (en) * 2000-01-14 2004-02-29 H. Lundbeck A/S Method for the preparation of 5-cyanophthalide
NL1017417C1 (nl) 2000-03-03 2001-03-16 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
NZ521201A (en) * 2000-03-13 2004-02-27 H Method for the preparation of citalopram
NL1017500C1 (nl) 2000-03-13 2001-04-26 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
EP1265881A1 (en) * 2000-03-13 2002-12-18 H. Lundbeck A/S Stepwise alkylation of 5-substituted 1-(4-fluorophenyl)-1,3-dihydroisobenzofurans
MXPA02008653A (es) 2000-03-14 2003-02-24 Lundbeck & Co As H Metodo para la preparacion de citalopram.
JP2003527388A (ja) * 2000-03-16 2003-09-16 ハー・ルンドベック・アクチエゼルスカベット ５−シアノ−１−（４−フルオロフェニル）−１，３−ジヒドロイソベンゾフランの製造方法
AR032455A1 (es) 2000-05-12 2003-11-12 Lundbeck & Co As H Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
CA2354877C (en) 2000-08-18 2006-05-02 H. Lundbeck A/S Method for the preparation of citalopram
NL1017525C1 (nl) 2000-12-22 2001-04-26 Lundbeck & Co As H Werkwijze voor de bereiding van zuiver Citalopram
AU2003222435A1 (en) * 2002-01-07 2003-07-24 Sun Pharmaceutical Industries Limited Process for the preparation of 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)- 1,3-dihydro-5-isobenzofuran carbonitrile
AR040970A1 (es) * 2002-08-12 2005-04-27 Lundbeck & Co As H Metodo para la separacion de intermediarios que pueden ser utilizados para la preparacion de escitalopram
US20050154052A1 (en) * 2003-03-24 2005-07-14 Hetero Drugs Limited Novel crystalline forms of (s)-citalopram oxalate
US20050143350A1 (en) * 2003-11-19 2005-06-30 Seed John C. Combination drug therapy to treat obesity
CN100569765C (zh) 2003-12-19 2009-12-16 杭州民生药业集团有限公司 西酞普兰中间体晶体碱
WO2009111031A2 (en) * 2008-03-04 2009-09-11 Intra-Cellular Therapies, Inc. Methods of treating vasomotor symptoms
US20100087664A1 (en) * 2008-10-07 2010-04-08 Ravindra Vedantham Preparation of citalopram and salts thereof
JP6222973B2 (ja) * 2013-04-19 2017-11-01 日本テルペン化学株式会社 ジベンジルトリチオカーボネート誘導体
CN103936702A (zh) * 2014-05-07 2014-07-23 成都诺维尔生物医药有限公司 艾司西酞普兰杂质j的合成方法

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1143703A (es) 1965-03-18
GB1526331A (en) * 1976-01-14 1978-09-27 Kefalas As Phthalanes
GB8419963D0 (en) 1984-08-06 1984-09-12 Lundbeck & Co As H Intermediate compound and method
GB8814057D0 (en) 1988-06-14 1988-07-20 Lundbeck & Co As H New enantiomers & their isolation
DE3926765A1 (de) 1989-08-12 1991-02-14 Hoechst Ag Verfahren zur verminderung von primaerem und sekundaerem amin in einem tertiaeren amin
US5296507A (en) 1990-09-06 1994-03-22 H.Lundbeck A/S Treatment of cerbrovascular disorders
DK213290D0 (da) 1990-09-06 1990-09-06 Lundbeck & Co As H Treatment of cerebrovascular disorders
DE19626659A1 (de) 1996-07-03 1998-01-08 Basf Ag Verfahren zur Herstellung von Phthaliden
DE19627697A1 (de) 1996-07-10 1998-01-15 Basf Ag Verfahren zur Herstellung von Phthaliden
ZA9711376B (en) 1996-12-20 1998-07-21 Lundbeck & Co As H Indole or dihydroindole derivatives
KR100357975B1 (ko) 1997-07-08 2002-10-25 하. 룬트벡 아크티에 셀스카브 시탈로프램의 제조방법
UA62985C2 (en) 1997-11-10 2004-01-15 Lunnbeck As H A method for the preparation of citalopram
CN1286687A (zh) 1997-11-11 2001-03-07 H·隆德贝克有限公司 制备西酞普兰的方法
DE69904853T2 (de) 1998-10-20 2003-09-04 Lundbeck As Valby H Verfahren zur herstellung von citalopram
CA2356188C (en) 1998-12-23 2006-05-23 H. Lundbeck A/S Method for the preparation of 5-cyanophthalide
AR022329A1 (es) 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
NZ514671A (en) 1999-04-14 2003-10-31 H Method for the preparation of citalopram
ITMI991581A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991579A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ES2229774T3 (es) 1999-10-25 2005-04-16 H. Lundbeck A/S Metodo para la preparacion de citalopram.
US6310222B1 (en) 1999-11-01 2001-10-30 Sumika Fine Chemicals Co., Ltd. Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
FR2805812A1 (fr) 2000-02-24 2001-09-07 Lundbeck & Co As H Procede de preparation du citalopram
IES20010143A2 (en) 2000-02-24 2001-07-25 Lundbeck & Co As H Method for the preparation of citalopram
GB0005477D0 (en) * 2000-03-07 2000-04-26 Resolution Chemicals Limited Process for the preparation of citalopram
CA2354877C (en) 2000-08-18 2006-05-02 H. Lundbeck A/S Method for the preparation of citalopram
NL1017525C1 (nl) 2000-12-22 2001-04-26 Lundbeck & Co As H Werkwijze voor de bereiding van zuiver Citalopram
IL147162A0 (en) 2000-12-28 2002-08-14 Lundbeck & Co As H Process for the preparation of pure citalopram

Also Published As

Publication number Publication date
MEP2208A (xx) 2010-02-10
SK287236B6 (sk) 2010-04-07
BE1013443A6 (fr) 2002-01-15
GB2362647A (en) 2001-11-28
UA71676C2 (en) 2004-12-15
IL144817A0 (en) 2002-06-30
IS6048A (is) 2001-10-19
HUP0103291A3 (en) 2003-02-28
ATE281448T1 (de) 2004-11-15
US6426422B1 (en) 2002-07-30
KR20030022378A (ko) 2003-03-15
ES2170735A1 (es) 2002-08-01
CA2354880A1 (en) 2002-01-22
RS50258B (sr) 2009-07-15
DE10140029A1 (de) 2002-05-02
CZ20012959A3 (cs) 2002-04-17
EA200300277A1 (ru) 2003-08-28
FR2813078A1 (fr) 2002-02-22
CN1222517C (zh) 2005-10-12
CA2354877A1 (en) 2002-02-18
SK287008B6 (sk) 2009-09-07
AU2001100278B4 (en) 2001-11-29
CN1339435A (zh) 2002-03-13
JP2004506730A (ja) 2004-03-04
ES2170735B2 (es) 2003-09-16
FI20011621A0 (fi) 2001-08-09
GR1004074B (el) 2002-11-26
MXPA03001329A (es) 2003-06-06
CA2354877C (en) 2006-05-02
EA005811B1 (ru) 2005-06-30
AU2001279608B2 (en) 2006-10-05
GB2365865B (en) 2002-07-17
AU7960901A (en) 2002-03-04
SK3222003A3 (en) 2003-08-05
BG65964B1 (bg) 2010-07-30
DK200101219A (da) 2002-02-19
NL1018775C1 (nl) 2001-10-24
DE60106932D1 (de) 2004-12-09
HK1044538A1 (en) 2002-10-25
HUP0103291A2 (hu) 2002-05-29
NO20013942D0 (no) 2001-08-14
NO20013943L (no) 2002-02-19
HK1068069A1 (en) 2005-04-22
EP1309582A1 (en) 2003-05-14
KR20030022385A (ko) 2003-03-15
BG65965B1 (bg) 2010-07-30
BG107583A (bg) 2004-01-30
GB0119734D0 (en) 2001-10-03
HK1047086A1 (en) 2003-02-07
AU7960801A (en) 2002-03-04
FI20011621A (fi) 2002-02-19
NO326570B1 (no) 2009-01-12
NL1018776C1 (nl) 2001-10-24
IS2120B (is) 2006-06-15
WO2002016341A1 (en) 2002-02-28
FI20011622A (fi) 2002-02-19
IS2121B (is) 2006-06-15
CL2008002412A1 (es) 2009-01-02
UA72340C2 (uk) 2005-02-15
AR029598A1 (es) 2003-07-10
NZ523877A (en) 2004-08-27
GB2365865A (en) 2002-02-27
GB2362647B (en) 2002-09-18
FI20011622A0 (fi) 2001-08-09
HUP0103295A3 (en) 2005-01-28
PL359825A1 (en) 2004-09-06
CZ294746B6 (cs) 2005-03-16
PL359969A1 (en) 2004-09-06
EP1309581A1 (en) 2003-05-14
HRP20030064A2 (en) 2005-02-28
IL144816A0 (en) 2002-06-30
CH691968A5 (de) 2001-12-14
ES2170734B2 (es) 2003-09-16
US20020025982A1 (en) 2002-02-28
EA005946B1 (ru) 2005-08-25
ES2170734A1 (es) 2002-08-01
DK1309581T3 (da) 2005-03-14
CN1515564A (zh) 2004-07-28
AT4946U1 (de) 2002-01-25
ATE281447T1 (de) 2004-11-15
CL2008002673A1 (es) 2009-01-02
PT1309582E (pt) 2005-03-31
NZ523853A (en) 2004-07-30
FR2813077B1 (fr) 2004-08-20
HRP20030065A2 (en) 2005-02-28
SK3202003A3 (en) 2003-08-05
AU2001100271A4 (en) 2001-09-13
NO326772B1 (no) 2009-02-16
DE60106932T2 (de) 2005-11-03
CH691969A5 (de) 2001-12-14
DK1309582T3 (da) 2005-03-14
EP1309582B1 (en) 2004-11-03
CN1239490C (zh) 2006-02-01
HU0103291D0 (en) 2001-10-28
MXPA03000913A (es) 2003-06-24
JP2004506729A (ja) 2004-03-04
RS50287B (sr) 2009-09-08
YU6903A (sh) 2006-05-25
ZA200106683B (en) 2002-08-05
IES20010760A2 (en) 2002-02-20
GB0119733D0 (en) 2001-10-03
WO2002016342A1 (en) 2002-02-28
ES2228920T3 (es) 2005-04-16
FR2813078B1 (fr) 2004-04-02
YU11503A (sh) 2006-05-25
FR2813077A1 (fr) 2002-02-22
DE60106933T2 (de) 2005-12-01
KR100887206B1 (ko) 2009-03-06
AR029597A1 (es) 2003-07-10
AT5026U1 (de) 2002-02-25
KR100887207B1 (ko) 2009-03-06
EA200300279A1 (ru) 2003-08-28
SI1309582T1 (en) 2005-06-30
AU2001100271B4 (en) 2001-11-29
AU2001100278A4 (en) 2001-09-13
BE1013444A6 (fr) 2002-01-15
DE10140028A1 (de) 2002-04-18
HUP0103295A2 (hu) 2002-05-29
US20020026062A1 (en) 2002-02-28
HK1047086B (zh) 2005-04-22
CZ295863B6 (cs) 2005-11-16
IL144816A (en) 2005-09-25
ES2230347T3 (es) 2005-05-01
EP1309581B1 (en) 2004-11-03
DE60106933D1 (de) 2004-12-09
DK200101216A (da) 2002-02-19
IS6047A (is) 2001-10-20
NO20013943D0 (no) 2001-08-14
CN1339436A (zh) 2002-03-13
BG107584A (bg) 2004-01-30
CA2354880C (en) 2003-06-03
CZ20012958A3 (cs) 2002-04-17
SI1309581T1 (en) 2005-04-30
US6509483B2 (en) 2003-01-21
NO20013942L (no) 2002-02-19
HK1044538B (zh) 2006-07-07
AR066694A2 (es) 2009-09-09
PT1309581E (pt) 2005-03-31
CN1159307C (zh) 2004-07-28
AU2001279609B2 (en) 2007-09-06
GR20010100398A (el) 2002-05-24
IES20010761A2 (en) 2002-02-20

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