FI20011622A0 - Menetelmä sitalopraamin valmistamiseksi - Google Patents

Menetelmä sitalopraamin valmistamiseksi

Info

Publication number
FI20011622A0
FI20011622A0 FI20011622A FI20011622A FI20011622A0 FI 20011622 A0 FI20011622 A0 FI 20011622A0 FI 20011622 A FI20011622 A FI 20011622A FI 20011622 A FI20011622 A FI 20011622A FI 20011622 A0 FI20011622 A0 FI 20011622A0
Authority
FI
Finland
Prior art keywords
citalopram
preparation
Prior art date
Application number
FI20011622A
Other languages
English (en)
Swedish (sv)
Other versions
FI20011622A (fi
Inventor
Hans Petersen
Haleh Ahmadian
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of FI20011622A0 publication Critical patent/FI20011622A0/fi
Publication of FI20011622A publication Critical patent/FI20011622A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse
FI20011622A 2000-08-18 2001-08-09 Menetelmä sitalopraamin valmistamiseksi FI20011622A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DKPA200001231 2000-08-18

Publications (2)

Publication Number Publication Date
FI20011622A0 true FI20011622A0 (fi) 2001-08-09
FI20011622A FI20011622A (fi) 2002-02-19

Family

ID=8159660

Family Applications (2)

Application Number Title Priority Date Filing Date
FI20011621A FI20011621A (fi) 2000-08-18 2001-08-09 Menetelmä sitalopraamin valmistamiseksi
FI20011622A FI20011622A (fi) 2000-08-18 2001-08-09 Menetelmä sitalopraamin valmistamiseksi

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FI20011621A FI20011621A (fi) 2000-08-18 2001-08-09 Menetelmä sitalopraamin valmistamiseksi

Country Status (41)

Country Link
US (2) US6426422B1 (fi)
EP (2) EP1309581B1 (fi)
JP (2) JP2004506730A (fi)
KR (2) KR100887206B1 (fi)
CN (3) CN1222517C (fi)
AR (3) AR029597A1 (fi)
AT (4) ATE281447T1 (fi)
AU (6) AU2001279608B2 (fi)
BE (2) BE1013443A6 (fi)
BG (2) BG65965B1 (fi)
CA (2) CA2354877C (fi)
CH (2) CH691968A5 (fi)
CL (2) CL2008002412A1 (fi)
CZ (2) CZ294746B6 (fi)
DE (4) DE60106933T2 (fi)
DK (4) DK200101219A (fi)
EA (2) EA005946B1 (fi)
ES (4) ES2230347T3 (fi)
FI (2) FI20011621A (fi)
FR (2) FR2813077B1 (fi)
GB (2) GB2365865B (fi)
GR (1) GR1004074B (fi)
HK (3) HK1044538B (fi)
HR (2) HRP20030065A2 (fi)
HU (2) HUP0103291A3 (fi)
IE (2) IES20010761A2 (fi)
IL (2) IL144817A0 (fi)
IS (2) IS2120B (fi)
ME (2) MEP2208A (fi)
MX (2) MXPA03000913A (fi)
NL (2) NL1018775C1 (fi)
NO (2) NO326570B1 (fi)
NZ (2) NZ523877A (fi)
PL (2) PL359969A1 (fi)
PT (2) PT1309582E (fi)
RS (2) RS50258B (fi)
SI (2) SI1309582T1 (fi)
SK (2) SK287236B6 (fi)
UA (2) UA72340C2 (fi)
WO (2) WO2002016342A1 (fi)
ZA (1) ZA200106683B (fi)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR022329A1 (es) 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
KR100604156B1 (ko) * 1999-04-14 2006-07-25 하. 룬트벡 아크티에 셀스카브 시탈로프람의 제조방법
ITMI991581A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
CA2291133C (en) 1999-10-25 2003-06-17 H. Lundbeck A/S Method for the preparation of citalopram
AR026063A1 (es) 1999-11-01 2002-12-26 Lundbeck & Co As H Metodo para la preparacion de 5-carboxiftalida.
SI1246812T1 (en) 1999-12-28 2004-08-31 H. Lundbeck A/S Method for the preparation of citalopram
CA2395733C (en) 1999-12-30 2007-03-20 H. Lundbeck A/S Method for the preparation of citalopram
SI1254129T1 (en) * 2000-01-14 2004-02-29 H. Lundbeck A/S Method for the preparation of 5-cyanophthalide
NL1017417C1 (nl) 2000-03-03 2001-03-16 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
AU2001239210A1 (en) * 2000-03-13 2001-09-24 H. Lundbeck A/S Stepwise alkylation of 5-substituted 1-(4-fluorophenyl)-1,3-dihydroisobenzofurans
EP1265883A1 (en) 2000-03-13 2002-12-18 H. Lundbeck A/S Method for the preparation of citalopram
IES20010206A2 (en) 2000-03-13 2002-03-06 Lundbeck & Co As H Method for the preparation of citalopram
AU2001239213A1 (en) 2000-03-14 2001-09-24 H Lundbeck A/S Method for the preparation of citalopram
CA2402869A1 (en) * 2000-03-16 2001-09-20 Hans Petersen Method for the preparation of 5-cyano-1-(4-fluorophenyl)-1,3-dihydroisobenzofurans
AR032455A1 (es) 2000-05-12 2003-11-12 Lundbeck & Co As H Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
FI20011621A (fi) 2000-08-18 2002-02-19 Lundbeck & Co As H Menetelmä sitalopraamin valmistamiseksi
WO2001045483A2 (en) 2000-12-22 2001-06-28 H. Lundbeck A/S Method for the preparation of pure citalopram
AU2003222435A1 (en) * 2002-01-07 2003-07-24 Sun Pharmaceutical Industries Limited Process for the preparation of 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)- 1,3-dihydro-5-isobenzofuran carbonitrile
TWI306846B (en) * 2002-08-12 2009-03-01 Lundbeck & Co As H Method for the separation of intermediates which may be used for the preparation of escitalopram
AU2003223105A1 (en) * 2003-03-24 2004-10-18 Hetero Drugs Limited Novel crystalline forms of (s)-citalopram oxalate
US20050143350A1 (en) * 2003-11-19 2005-06-30 Seed John C. Combination drug therapy to treat obesity
CN100569765C (zh) 2003-12-19 2009-12-16 杭州民生药业集团有限公司 西酞普兰中间体晶体碱
US9339500B2 (en) * 2008-03-04 2016-05-17 Intra-Cellular Therapies, Inc. Methods of treating vasomotor symptoms
US20100087664A1 (en) * 2008-10-07 2010-04-08 Ravindra Vedantham Preparation of citalopram and salts thereof
JP6222973B2 (ja) * 2013-04-19 2017-11-01 日本テルペン化学株式会社 ジベンジルトリチオカーボネート誘導体
CN103936702A (zh) * 2014-05-07 2014-07-23 成都诺维尔生物医药有限公司 艾司西酞普兰杂质j的合成方法

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1143702A (fi) 1965-03-18
GB1526331A (en) * 1976-01-14 1978-09-27 Kefalas As Phthalanes
GB8419963D0 (en) 1984-08-06 1984-09-12 Lundbeck & Co As H Intermediate compound and method
GB8814057D0 (en) 1988-06-14 1988-07-20 Lundbeck & Co As H New enantiomers & their isolation
DE3926765A1 (de) 1989-08-12 1991-02-14 Hoechst Ag Verfahren zur verminderung von primaerem und sekundaerem amin in einem tertiaeren amin
DK213290D0 (da) 1990-09-06 1990-09-06 Lundbeck & Co As H Treatment of cerebrovascular disorders
US5296507A (en) 1990-09-06 1994-03-22 H.Lundbeck A/S Treatment of cerbrovascular disorders
DE19626659A1 (de) 1996-07-03 1998-01-08 Basf Ag Verfahren zur Herstellung von Phthaliden
DE19627697A1 (de) 1996-07-10 1998-01-15 Basf Ag Verfahren zur Herstellung von Phthaliden
ZA9711376B (en) 1996-12-20 1998-07-21 Lundbeck & Co As H Indole or dihydroindole derivatives
DK1015416T3 (da) 1997-07-08 2001-11-05 Lundbeck & Co As H Fremgangsmåde til fremstilling af citalopram
UA62985C2 (en) 1997-11-10 2004-01-15 Lunnbeck As H A method for the preparation of citalopram
BR9714925A (pt) 1997-11-11 2003-07-22 Lundbeck & Co As H Método para preparação de citalopran, composto e composição farmacêutica antidepressiva
NZ510858A (en) 1998-10-20 2003-11-28 H Method for the preparation of citalopram
PL203275B1 (pl) * 1998-12-23 2009-09-30 Lundbeck & Co As H Sposób wytwarzania 5-cyjanoftalidu
AR022329A1 (es) 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
KR100604156B1 (ko) 1999-04-14 2006-07-25 하. 룬트벡 아크티에 셀스카브 시탈로프람의 제조방법
ITMI991579A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991581A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
SK287139B6 (sk) 1999-10-25 2010-01-07 H. Lundbeck A/S Spôsob prípravy citalopramu
US6310222B1 (en) 1999-11-01 2001-10-30 Sumika Fine Chemicals Co., Ltd. Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
IES20010143A2 (en) 2000-02-24 2001-07-25 Lundbeck & Co As H Method for the preparation of citalopram
NL1017415C1 (nl) 2000-02-24 2001-05-18 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
GB0005477D0 (en) 2000-03-07 2000-04-26 Resolution Chemicals Limited Process for the preparation of citalopram
FI20011621A (fi) 2000-08-18 2002-02-19 Lundbeck & Co As H Menetelmä sitalopraamin valmistamiseksi
WO2001045483A2 (en) 2000-12-22 2001-06-28 H. Lundbeck A/S Method for the preparation of pure citalopram
KR100430746B1 (ko) 2000-12-28 2004-05-10 하. 룬트벡 아크티에 셀스카브 순수한 시탈로프람의 제조방법

Also Published As

Publication number Publication date
DK200101219A (da) 2002-02-19
SK287236B6 (sk) 2010-04-07
GB0119734D0 (en) 2001-10-03
CN1339435A (zh) 2002-03-13
KR100887206B1 (ko) 2009-03-06
GB2365865A (en) 2002-02-27
PL359825A1 (en) 2004-09-06
DK200101216A (da) 2002-02-19
CZ20012958A3 (cs) 2002-04-17
DE60106933D1 (de) 2004-12-09
DE60106932T2 (de) 2005-11-03
EA005811B1 (ru) 2005-06-30
HK1047086A1 (en) 2003-02-07
CZ294746B6 (cs) 2005-03-16
CA2354877A1 (en) 2002-02-18
WO2002016341A1 (en) 2002-02-28
SI1309582T1 (en) 2005-06-30
IL144817A0 (en) 2002-06-30
US6426422B1 (en) 2002-07-30
RS50287B (sr) 2009-09-08
YU6903A (sh) 2006-05-25
AR029597A1 (es) 2003-07-10
AU2001100271A4 (en) 2001-09-13
CZ295863B6 (cs) 2005-11-16
IES20010761A2 (en) 2002-02-20
FI20011622A (fi) 2002-02-19
DE60106932D1 (de) 2004-12-09
DK1309581T3 (da) 2005-03-14
NL1018776C1 (nl) 2001-10-24
EP1309582A1 (en) 2003-05-14
EA200300279A1 (ru) 2003-08-28
CA2354880C (en) 2003-06-03
HRP20030064A2 (en) 2005-02-28
NO20013943D0 (no) 2001-08-14
BG65965B1 (bg) 2010-07-30
AU2001100278B4 (en) 2001-11-29
NO20013942L (no) 2002-02-19
GB2362647A (en) 2001-11-28
BE1013443A6 (fr) 2002-01-15
JP2004506730A (ja) 2004-03-04
FR2813077B1 (fr) 2004-08-20
US20020026062A1 (en) 2002-02-28
NO20013943L (no) 2002-02-19
HK1044538B (zh) 2006-07-07
BG65964B1 (bg) 2010-07-30
IS2120B (is) 2006-06-15
EP1309582B1 (en) 2004-11-03
AU2001100278A4 (en) 2001-09-13
MXPA03000913A (es) 2003-06-24
HUP0103295A2 (hu) 2002-05-29
MEP2208A (xx) 2010-02-10
CN1339436A (zh) 2002-03-13
AU7960901A (en) 2002-03-04
CL2008002673A1 (es) 2009-01-02
HK1044538A1 (en) 2002-10-25
NO326772B1 (no) 2009-02-16
CH691968A5 (de) 2001-12-14
WO2002016342A1 (en) 2002-02-28
EP1309581B1 (en) 2004-11-03
SI1309581T1 (en) 2005-04-30
CZ20012959A3 (cs) 2002-04-17
UA72340C2 (uk) 2005-02-15
ATE281448T1 (de) 2004-11-15
AU2001279608B2 (en) 2006-10-05
CN1159307C (zh) 2004-07-28
PT1309582E (pt) 2005-03-31
AU2001279609B2 (en) 2007-09-06
HRP20030065A2 (en) 2005-02-28
AU2001100271B4 (en) 2001-11-29
IS2121B (is) 2006-06-15
AR066694A2 (es) 2009-09-09
BG107583A (bg) 2004-01-30
US20020025982A1 (en) 2002-02-28
NZ523853A (en) 2004-07-30
PT1309581E (pt) 2005-03-31
GR20010100398A (el) 2002-05-24
KR20030022378A (ko) 2003-03-15
CH691969A5 (de) 2001-12-14
DE10140028A1 (de) 2002-04-18
CN1239490C (zh) 2006-02-01
NZ523877A (en) 2004-08-27
HK1068069A1 (en) 2005-04-22
EA005946B1 (ru) 2005-08-25
GB2362647B (en) 2002-09-18
RS50258B (sr) 2009-07-15
IS6047A (is) 2001-10-20
IL144816A0 (en) 2002-06-30
NO20013942D0 (no) 2001-08-14
AR029598A1 (es) 2003-07-10
CN1515564A (zh) 2004-07-28
AT5026U1 (de) 2002-02-25
YU11503A (sh) 2006-05-25
AU7960801A (en) 2002-03-04
CL2008002412A1 (es) 2009-01-02
DE60106933T2 (de) 2005-12-01
IES20010760A2 (en) 2002-02-20
HUP0103291A2 (hu) 2002-05-29
MXPA03001329A (es) 2003-06-06
CN1222517C (zh) 2005-10-12
DE10140029A1 (de) 2002-05-02
HUP0103295A3 (en) 2005-01-28
EA200300277A1 (ru) 2003-08-28
US6509483B2 (en) 2003-01-21
FI20011621A (fi) 2002-02-19
IS6048A (is) 2001-10-19
ZA200106683B (en) 2002-08-05
ES2170735A1 (es) 2002-08-01
CA2354877C (en) 2006-05-02
ES2230347T3 (es) 2005-05-01
SK3222003A3 (en) 2003-08-05
JP2004506729A (ja) 2004-03-04
GB0119733D0 (en) 2001-10-03
HUP0103291A3 (en) 2003-02-28
BE1013444A6 (fr) 2002-01-15
CA2354880A1 (en) 2002-01-22
PL359969A1 (en) 2004-09-06
ATE281447T1 (de) 2004-11-15
UA71676C2 (en) 2004-12-15
KR20030022385A (ko) 2003-03-15
BG107584A (bg) 2004-01-30
GB2365865B (en) 2002-07-17
IL144816A (en) 2005-09-25
FR2813078A1 (fr) 2002-02-22
FR2813077A1 (fr) 2002-02-22
ES2170734A1 (es) 2002-08-01
NO326570B1 (no) 2009-01-12
ES2170735B2 (es) 2003-09-16
FI20011621A0 (fi) 2001-08-09
HK1047086B (zh) 2005-04-22
AT4946U1 (de) 2002-01-25
KR100887207B1 (ko) 2009-03-06
ES2170734B2 (es) 2003-09-16
DK1309582T3 (da) 2005-03-14
MEP2308A (xx) 2010-02-10
NL1018775C1 (nl) 2001-10-24
GR1004074B (el) 2002-11-26
FR2813078B1 (fr) 2004-04-02
ES2228920T3 (es) 2005-04-16
SK3202003A3 (en) 2003-08-05
EP1309581A1 (en) 2003-05-14
SK287008B6 (sk) 2009-09-07
HU0103291D0 (en) 2001-10-28

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