DK1387828T3 - Fremgangsmåde til fremstilling af biperiden IV - Google Patents
Fremgangsmåde til fremstilling af biperiden IVInfo
- Publication number
- DK1387828T3 DK1387828T3 DK02735369T DK02735369T DK1387828T3 DK 1387828 T3 DK1387828 T3 DK 1387828T3 DK 02735369 T DK02735369 T DK 02735369T DK 02735369 T DK02735369 T DK 02735369T DK 1387828 T3 DK1387828 T3 DK 1387828T3
- Authority
- DK
- Denmark
- Prior art keywords
- biperiden
- exo
- preparation
- propanone
- hept
- Prior art date
Links
- YSXKPIUOCJLQIE-UHFFFAOYSA-N biperiden Chemical compound C1C(C=C2)CC2C1C(C=1C=CC=CC=1)(O)CCN1CCCCC1 YSXKPIUOCJLQIE-UHFFFAOYSA-N 0.000 title abstract 2
- 229960003003 biperiden Drugs 0.000 title abstract 2
- LCCCAFOMMQBWHG-UHFFFAOYSA-N 1-methylidenepiperidin-1-ium Chemical compound C=[N+]1CCCCC1 LCCCAFOMMQBWHG-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- RTZKZFJDLAIYFH-UHFFFAOYSA-N ether Substances CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- -1 phenylmagnesium compound Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Steroid Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10124453A DE10124453A1 (de) | 2001-05-18 | 2001-05-18 | Verfahren zur Herstellung von Biperiden |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1387828T3 true DK1387828T3 (da) | 2006-02-27 |
Family
ID=7685405
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK02735369T DK1387828T3 (da) | 2001-05-18 | 2002-05-17 | Fremgangsmåde til fremstilling af biperiden IV |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7501519B2 (da) |
| EP (1) | EP1387828B1 (da) |
| AT (1) | ATE306471T1 (da) |
| AU (1) | AU2002310828A1 (da) |
| DE (2) | DE10124453A1 (da) |
| DK (1) | DK1387828T3 (da) |
| ES (1) | ES2250653T3 (da) |
| WO (1) | WO2002096874A2 (da) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10124453A1 (de) | 2001-05-18 | 2002-11-21 | Abbott Gmbh & Co Kg | Verfahren zur Herstellung von Biperiden |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1005067B (de) * | 1953-03-14 | 1957-03-28 | Knoll Ag | Verfahren zur Herstellung von bicyclisch substituierten Aminopropanolen |
| US2789110A (en) * | 1953-03-14 | 1957-04-16 | Knoll Ag | Amino alcohols substituted by bicycloalkyl residues and a process of making same |
| DE10124449A1 (de) * | 2001-05-18 | 2002-11-21 | Abbott Gmbh & Co Kg | Verfahren zur Herstellung von Biperiden |
| DE10124453A1 (de) | 2001-05-18 | 2002-11-21 | Abbott Gmbh & Co Kg | Verfahren zur Herstellung von Biperiden |
-
2001
- 2001-05-18 DE DE10124453A patent/DE10124453A1/de not_active Withdrawn
-
2002
- 2002-05-17 EP EP02735369A patent/EP1387828B1/de not_active Expired - Lifetime
- 2002-05-17 DE DE50204538T patent/DE50204538D1/de not_active Expired - Lifetime
- 2002-05-17 DK DK02735369T patent/DK1387828T3/da active
- 2002-05-17 ES ES02735369T patent/ES2250653T3/es not_active Expired - Lifetime
- 2002-05-17 AT AT02735369T patent/ATE306471T1/de active
- 2002-05-17 WO PCT/EP2002/005497 patent/WO2002096874A2/de not_active Ceased
- 2002-05-17 AU AU2002310828A patent/AU2002310828A1/en not_active Abandoned
- 2002-05-17 US US10/478,384 patent/US7501519B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US7501519B2 (en) | 2009-03-10 |
| EP1387828B1 (de) | 2005-10-12 |
| US20040186294A1 (en) | 2004-09-23 |
| WO2002096874A2 (de) | 2002-12-05 |
| ATE306471T1 (de) | 2005-10-15 |
| ES2250653T3 (es) | 2006-04-16 |
| DE50204538D1 (de) | 2005-11-17 |
| WO2002096874A3 (de) | 2003-01-30 |
| DE10124453A1 (de) | 2002-11-21 |
| AU2002310828A1 (en) | 2002-12-09 |
| EP1387828A2 (de) | 2004-02-11 |
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