LU86562A1 - Nouvelles substances antibiotiques et antitumorales,procede pour leur otbention et isolation;compositions pharmaceutiques les contenant - Google Patents

Nouvelles substances antibiotiques et antitumorales,procede pour leur otbention et isolation;compositions pharmaceutiques les contenant Download PDF

Info

Publication number
LU86562A1
LU86562A1 LU86562A LU86562A LU86562A1 LU 86562 A1 LU86562 A1 LU 86562A1 LU 86562 A LU86562 A LU 86562A LU 86562 A LU86562 A LU 86562A LU 86562 A1 LU86562 A1 LU 86562A1
Authority
LU
Luxembourg
Prior art keywords
bbm
volume
obtaining
methanol
hydrolysis
Prior art date
Application number
LU86562A
Other languages
English (en)
French (fr)
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of LU86562A1 publication Critical patent/LU86562A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/14—Acyclic radicals, not substituted by cyclic structures attached to a sulfur, selenium or tellurium atom of a saccharide radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/06—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/03—Actinomadura

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
LU86562A 1985-08-27 1986-08-26 Nouvelles substances antibiotiques et antitumorales,procede pour leur otbention et isolation;compositions pharmaceutiques les contenant LU86562A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US77033585A 1985-08-27 1985-08-27
US77033585 1985-08-27

Publications (1)

Publication Number Publication Date
LU86562A1 true LU86562A1 (fr) 1987-03-06

Family

ID=25088206

Family Applications (1)

Application Number Title Priority Date Filing Date
LU86562A LU86562A1 (fr) 1985-08-27 1986-08-26 Nouvelles substances antibiotiques et antitumorales,procede pour leur otbention et isolation;compositions pharmaceutiques les contenant

Country Status (26)

Country Link
JP (2) JPH0733393B2 (es)
KR (1) KR920010226B1 (es)
AT (1) AT392971B (es)
AU (1) AU604464B2 (es)
BE (1) BE905332A (es)
CA (1) CA1307256C (es)
CH (1) CH668598A5 (es)
CY (1) CY1676A (es)
DE (1) DE3629052C2 (es)
DK (1) DK170671B1 (es)
ES (1) ES2002728A6 (es)
FI (1) FI83422C (es)
FR (1) FR2586686B1 (es)
GB (1) GB2179649A (es)
GR (1) GR862160B (es)
HK (1) HK793A (es)
HU (1) HU197915B (es)
IE (1) IE59204B1 (es)
IL (1) IL79519A0 (es)
IT (1) IT1229176B (es)
LU (1) LU86562A1 (es)
NL (1) NL8602165A (es)
PT (1) PT83261B (es)
SE (2) SE469632B (es)
SG (1) SG109692G (es)
ZA (1) ZA865796B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2177518T3 (es) * 1987-01-30 2002-12-16 American Cyanamid Co Derivados dihidro de los antibioticos ll-e33288.
US4916065A (en) * 1988-06-10 1990-04-10 Bristol-Myers Company BU-3420T Antitumor antibiotic
US5028536A (en) * 1989-03-15 1991-07-02 Bristol-Myers Squibb Company Antitumor antibiotic BMY-41339
US5086045A (en) * 1989-03-15 1992-02-04 Bristol-Myers Squibb Company Antitumor antibiotic
CA2027601A1 (en) * 1989-11-06 1991-05-07 Koko Sugawara Antitumor antibiotic bu-3983t
CA2039789A1 (en) * 1990-04-27 1991-10-28 Samuel J. Danishefsky Calicheamicinone, derivatives and analogs thereof and methods of making the same
US5116845A (en) * 1990-05-04 1992-05-26 Bristol-Myers Company BU-3420T antitumor antibiotic
US5264586A (en) * 1991-07-17 1993-11-23 The Scripps Research Institute Analogs of calicheamicin gamma1I, method of making and using the same

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3148023A1 (de) * 1981-12-04 1983-06-09 Rudolf Dipl.-Ing. 8901 Oberottmarshausen Fischer Heizungskessel fuer heisse rauchgase
US4578271A (en) * 1982-05-24 1986-03-25 Fujisawa Pharmaceutical Co., Ltd. Biologically active WS 6049 substances, a process for the production thereof and their pharmaceutical compositions
NZ208013A (en) * 1983-05-16 1987-07-31 Bristol Myers Co Antitumour antibiotic bbm-1675 and production by cultivating actinomadura verrucosospora
JPS606194A (ja) * 1983-06-23 1985-01-12 Meiji Seika Kaisha Ltd 新規抗生物質ｓｆ−２２８８及びその製造法
US4530835A (en) * 1983-07-08 1985-07-23 Warner-Lambert Company CL-1577 Antibiotic compounds and their production

Also Published As

Publication number Publication date
DK406086A (da) 1987-02-28
IT8621527A0 (it) 1986-08-26
IL79519A0 (en) 1986-10-31
GB2179649B (es) 1989-10-25
ZA865796B (en) 1987-04-29
SE469632B (sv) 1993-08-09
DK170671B1 (da) 1995-11-27
ATA231786A (de) 1990-12-15
IE862280L (en) 1987-02-27
IT1229176B (it) 1991-07-23
GR862160B (en) 1986-12-31
FI83422C (fi) 1991-07-10
JPH0733393B2 (ja) 1995-04-12
GB2179649A (en) 1987-03-11
KR870002269A (ko) 1987-03-30
SE8603597D0 (sv) 1986-08-26
FI83422B (fi) 1991-03-28
HUT44035A (en) 1988-01-28
SE9200428D0 (sv) 1992-02-13
ES2002728A6 (es) 1988-10-01
GB8620118D0 (en) 1986-10-01
AT392971B (de) 1991-07-25
IE59204B1 (en) 1994-01-26
HU197915B (en) 1989-06-28
NL8602165A (nl) 1987-03-16
FI863405A (fi) 1987-02-28
DE3629052A1 (de) 1987-05-07
SG109692G (en) 1992-12-24
PT83261A (en) 1986-09-01
DE3629052C2 (de) 1995-09-28
DK406086D0 (da) 1986-08-26
CA1307256C (en) 1992-09-08
AU604464B2 (en) 1990-12-20
AU6175186A (en) 1987-03-05
FI863405A0 (fi) 1986-08-22
FR2586686B1 (fr) 1990-02-02
JPH07233186A (ja) 1995-09-05
CH668598A5 (de) 1989-01-13
PT83261B (pt) 1989-05-12
BE905332A (fr) 1987-02-26
JPS62116589A (ja) 1987-05-28
SE9200428L (sv) 1993-08-14
CY1676A (en) 1993-10-10
SE8603597L (sv) 1987-02-28
FR2586686A1 (fr) 1987-03-06
HK793A (en) 1993-01-15
KR920010226B1 (ko) 1992-11-21

Similar Documents

Publication Publication Date Title
CH657139A5 (fr) Facteurs 1, 2, 3, 4 et 5 isoles purs de la teichomycine a(2) utiles notamment comme medicaments antibiotiques et procede pour leur preparation.
FR2555586A1 (fr) Complexe antibiotique bbm-2478
CH637160A5 (fr) Procede de fabrication de glucosides anthracyclines.
FR2569702A1 (fr) Nouvelle 4'-deschlororebeccamycine, composition pharmaceutique la contenant et procede pour sa preparation
LU81794A1 (fr) Nouveaux antibiotiques peptidiques et leur procede de production
LU86562A1 (fr) Nouvelles substances antibiotiques et antitumorales,procede pour leur otbention et isolation;compositions pharmaceutiques les contenant
CH647247A5 (fr) Composes antibiotiques-antitumoraux et leurs procedes de production.
EP0246975A1 (fr) Nouvelles substances immuno-suppressives, leur préparation par culture de streptomyces sp. (CBS 162.86) et les compositions pharmaceutiques qui les contiennent
FR2568892A1 (fr) Nouvel antibiotique sandramycine, procede de preparation de celui-ci, culture biologiquement pure du micro-organisme nocardioides sp, atcc no 39419, et composition pharmaceutique contenant la sandramycine
US5527820A (en) Antibiotics having immunosuppressive activity, delaminomycins and processes for the production of the same
KR100226305B1 (ko) 폴리히드록시 시클로펜탄유도체, 그의 제조방법 및 그의 치료적용도
FR2465742A1 (fr) Nouvel antibiotique utile comme agent d'inhibition de l'activite enzymatique de la glucosidase, procede pour sa production et utilisations
HU202591B (en) Process for producing antibiotic bu-3420t and pharmaceutical composition comprising such antibiotic
FR2502155A1 (fr) Nouveaux antibiotiques macrolides semi-synthetiques, procede microbiologique pour leur preparation et micro-organisme s'y rapportant, nouveaux produits intermediaires pour leur preparation et compositions pharmaceutiques les contenant
US4921700A (en) BBM-1675c and d antitumor antibiotics
LU85362A1 (fr) Nouveau complexe antibiotique antitumoral dit bbm-1675
JP3759207B2 (ja) 抗菌剤及び医薬組成物
CH643298A5 (fr) Procede de fabrication de nouveaux antibiotiques.
CH637137A5 (en) Antibiotic and process for its preparation
BE860210A (fr) Facteurs d et ke de la fortimicine utiles notamment comme antibiotique et leur procede de preparation
JPH0367077B2 (es)
JPH0426625A (ja) リゾリピン類を有効成分とする抗腫瘍剤
CA2568415A1 (fr) Nouvelle souche saccharothrix et ses antibiotiques derives, notamment mutactimycines et aldgamycines
JPH08176116A (ja) 新規抗生物質スパロキソマイシン
BE859236A (fr) Nouveaux antibiotiques anti-fumeurs, de type anthracycline