AU604464B2 - New BBM-1675C and D antitumor antibiotics - Google Patents

New BBM-1675C and D antitumor antibiotics Download PDF

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Publication number
AU604464B2
AU604464B2 AU61751/86A AU6175186A AU604464B2 AU 604464 B2 AU604464 B2 AU 604464B2 AU 61751/86 A AU61751/86 A AU 61751/86A AU 6175186 A AU6175186 A AU 6175186A AU 604464 B2 AU604464 B2 AU 604464B2
Authority
AU
Australia
Prior art keywords
bbm
exhibiting
methanol
spectrum
antitumor antibiotic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU61751/86A
Other languages
English (en)
Other versions
AU6175186A (en
Inventor
Jerzy Golik
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of AU6175186A publication Critical patent/AU6175186A/en
Application granted granted Critical
Publication of AU604464B2 publication Critical patent/AU604464B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/14—Acyclic radicals, not substituted by cyclic structures attached to a sulfur, selenium or tellurium atom of a saccharide radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/06—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/03—Actinomadura

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
AU61751/86A 1985-08-27 1986-08-22 New BBM-1675C and D antitumor antibiotics Ceased AU604464B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US77033585A 1985-08-27 1985-08-27
US770335 1985-08-27

Publications (2)

Publication Number Publication Date
AU6175186A AU6175186A (en) 1987-03-05
AU604464B2 true AU604464B2 (en) 1990-12-20

Family

ID=25088206

Family Applications (1)

Application Number Title Priority Date Filing Date
AU61751/86A Ceased AU604464B2 (en) 1985-08-27 1986-08-22 New BBM-1675C and D antitumor antibiotics

Country Status (26)

Country Link
JP (2) JPH0733393B2 (es)
KR (1) KR920010226B1 (es)
AT (1) AT392971B (es)
AU (1) AU604464B2 (es)
BE (1) BE905332A (es)
CA (1) CA1307256C (es)
CH (1) CH668598A5 (es)
CY (1) CY1676A (es)
DE (1) DE3629052C2 (es)
DK (1) DK170671B1 (es)
ES (1) ES2002728A6 (es)
FI (1) FI83422C (es)
FR (1) FR2586686B1 (es)
GB (1) GB2179649A (es)
GR (1) GR862160B (es)
HK (1) HK793A (es)
HU (1) HU197915B (es)
IE (1) IE59204B1 (es)
IL (1) IL79519A0 (es)
IT (1) IT1229176B (es)
LU (1) LU86562A1 (es)
NL (1) NL8602165A (es)
PT (1) PT83261B (es)
SE (2) SE469632B (es)
SG (1) SG109692G (es)
ZA (1) ZA865796B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2177518T3 (es) * 1987-01-30 2002-12-16 American Cyanamid Co Derivados dihidro de los antibioticos ll-e33288.
US4916065A (en) * 1988-06-10 1990-04-10 Bristol-Myers Company BU-3420T Antitumor antibiotic
US5028536A (en) * 1989-03-15 1991-07-02 Bristol-Myers Squibb Company Antitumor antibiotic BMY-41339
US5086045A (en) * 1989-03-15 1992-02-04 Bristol-Myers Squibb Company Antitumor antibiotic
CA2027601A1 (en) * 1989-11-06 1991-05-07 Koko Sugawara Antitumor antibiotic bu-3983t
CA2039789A1 (en) * 1990-04-27 1991-10-28 Samuel J. Danishefsky Calicheamicinone, derivatives and analogs thereof and methods of making the same
US5116845A (en) * 1990-05-04 1992-05-26 Bristol-Myers Company BU-3420T antitumor antibiotic
US5264586A (en) * 1991-07-17 1993-11-23 The Scripps Research Institute Analogs of calicheamicin gamma1I, method of making and using the same

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1488683A (en) * 1982-05-24 1983-12-01 Fujisawa Pharmaceutical Co., Ltd. Substances from actinomadura strains
AU2779184A (en) * 1983-05-16 1984-11-22 Bristol-Myers Company Antibiotic bbm-1675a and b, from actinomadura verrucosospora
US4530835A (en) * 1983-07-08 1985-07-23 Warner-Lambert Company CL-1577 Antibiotic compounds and their production

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3148023A1 (de) * 1981-12-04 1983-06-09 Rudolf Dipl.-Ing. 8901 Oberottmarshausen Fischer Heizungskessel fuer heisse rauchgase
JPS606194A (ja) * 1983-06-23 1985-01-12 Meiji Seika Kaisha Ltd 新規抗生物質ｓｆ−２２８８及びその製造法

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1488683A (en) * 1982-05-24 1983-12-01 Fujisawa Pharmaceutical Co., Ltd. Substances from actinomadura strains
AU2779184A (en) * 1983-05-16 1984-11-22 Bristol-Myers Company Antibiotic bbm-1675a and b, from actinomadura verrucosospora
US4530835A (en) * 1983-07-08 1985-07-23 Warner-Lambert Company CL-1577 Antibiotic compounds and their production

Also Published As

Publication number Publication date
DK406086A (da) 1987-02-28
IT8621527A0 (it) 1986-08-26
IL79519A0 (en) 1986-10-31
GB2179649B (es) 1989-10-25
ZA865796B (en) 1987-04-29
SE469632B (sv) 1993-08-09
DK170671B1 (da) 1995-11-27
ATA231786A (de) 1990-12-15
IE862280L (en) 1987-02-27
IT1229176B (it) 1991-07-23
GR862160B (en) 1986-12-31
FI83422C (fi) 1991-07-10
JPH0733393B2 (ja) 1995-04-12
GB2179649A (en) 1987-03-11
KR870002269A (ko) 1987-03-30
SE8603597D0 (sv) 1986-08-26
FI83422B (fi) 1991-03-28
HUT44035A (en) 1988-01-28
SE9200428D0 (sv) 1992-02-13
ES2002728A6 (es) 1988-10-01
GB8620118D0 (en) 1986-10-01
AT392971B (de) 1991-07-25
IE59204B1 (en) 1994-01-26
HU197915B (en) 1989-06-28
NL8602165A (nl) 1987-03-16
FI863405A (fi) 1987-02-28
DE3629052A1 (de) 1987-05-07
LU86562A1 (fr) 1987-03-06
SG109692G (en) 1992-12-24
PT83261A (en) 1986-09-01
DE3629052C2 (de) 1995-09-28
DK406086D0 (da) 1986-08-26
CA1307256C (en) 1992-09-08
AU6175186A (en) 1987-03-05
FI863405A0 (fi) 1986-08-22
FR2586686B1 (fr) 1990-02-02
JPH07233186A (ja) 1995-09-05
CH668598A5 (de) 1989-01-13
PT83261B (pt) 1989-05-12
BE905332A (fr) 1987-02-26
JPS62116589A (ja) 1987-05-28
SE9200428L (sv) 1993-08-14
CY1676A (en) 1993-10-10
SE8603597L (sv) 1987-02-28
FR2586686A1 (fr) 1987-03-06
HK793A (en) 1993-01-15
KR920010226B1 (ko) 1992-11-21

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