LT4482B - Nauji 1-aril(alkil)imidazolin-2-onai, turintys dipakeistą aminogrupė 4 padėtyje, pasižymintys antispazminiu veikimu, ir jų gavimo būdas - Google Patents

Nauji 1-aril(alkil)imidazolin-2-onai, turintys dipakeistą aminogrupė 4 padėtyje, pasižymintys antispazminiu veikimu, ir jų gavimo būdas Download PDF

Info

Publication number
LT4482B
LT4482B LT98-047A LT98047A LT4482B LT 4482 B LT4482 B LT 4482B LT 98047 A LT98047 A LT 98047A LT 4482 B LT4482 B LT 4482B
Authority
LT
Lithuania
Prior art keywords
morpholinimidazolin
compounds
imidazolin
alkyl
general formula
Prior art date
Application number
LT98-047A
Other languages
English (en)
Lithuanian (lt)
Other versions
LT98047A (en
Inventor
Hans-Joachim Lankau
Manfred Menzer
Klaus Unverferth
Karl Gewald
Harry Schafer
Original Assignee
Arzneimittelwerk Dresden Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7771261&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LT4482(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Arzneimittelwerk Dresden Gmbh filed Critical Arzneimittelwerk Dresden Gmbh
Publication of LT98047A publication Critical patent/LT98047A/xx
Publication of LT4482B publication Critical patent/LT4482B/lt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/88—Nitrogen atoms, e.g. allantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
LT98-047A 1995-09-05 1998-04-03 Nauji 1-aril(alkil)imidazolin-2-onai, turintys dipakeistą aminogrupė 4 padėtyje, pasižymintys antispazminiu veikimu, ir jų gavimo būdas LT4482B (lt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19532668A DE19532668A1 (de) 1995-09-05 1995-09-05 Neue, antikonvulsiv wirkende 1-Ar(alk)yl-imidazolin-2-one, die in 4-Stellung einen disubstituierten Amin-Rest enthalten, und Verfahren zu deren Herstellung

Publications (2)

Publication Number Publication Date
LT98047A LT98047A (en) 1998-10-26
LT4482B true LT4482B (lt) 1999-03-25

Family

ID=7771261

Family Applications (1)

Application Number Title Priority Date Filing Date
LT98-047A LT4482B (lt) 1995-09-05 1998-04-03 Nauji 1-aril(alkil)imidazolin-2-onai, turintys dipakeistą aminogrupė 4 padėtyje, pasižymintys antispazminiu veikimu, ir jų gavimo būdas

Country Status (32)

Country Link
EP (1) EP0863880B1 (fr)
JP (1) JP4030578B2 (fr)
CN (1) CN1103762C (fr)
AR (1) AR003502A1 (fr)
AT (1) ATE254606T1 (fr)
AU (1) AU700602B2 (fr)
BG (1) BG63917B1 (fr)
BR (1) BR9610359A (fr)
CA (1) CA2184871C (fr)
CZ (1) CZ291839B6 (fr)
DE (2) DE19532668A1 (fr)
DK (1) DK0863880T3 (fr)
EA (1) EA000535B1 (fr)
EE (1) EE03562B1 (fr)
ES (1) ES2208758T3 (fr)
FR (1) FR13C0049I2 (fr)
GE (1) GEP20022652B (fr)
HK (1) HK1015776A1 (fr)
HU (1) HU225956B1 (fr)
IL (1) IL123333A (fr)
LT (1) LT4482B (fr)
LU (1) LU92263I2 (fr)
NO (1) NO313829B1 (fr)
NZ (1) NZ315624A (fr)
PL (1) PL188287B1 (fr)
PT (1) PT863880E (fr)
SK (1) SK284868B6 (fr)
TR (1) TR199800476T1 (fr)
TW (1) TW422838B (fr)
UA (1) UA46790C2 (fr)
WO (1) WO1997009314A1 (fr)
ZA (1) ZA967014B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19721580A1 (de) * 1997-05-23 1998-11-26 Dresden Arzneimittel Verwendung von 1-Ar(alk)yl-imidazolin-2-one zur Behandlung von Angst- und Spannungszuständen
US20050070537A1 (en) 2002-10-10 2005-03-31 Chris Rundfeldt Use of dihydroimidazolones for the treatment of dogs
EP2027856A1 (fr) * 2003-07-11 2009-02-25 Boehringer Ingelheim Vetmedica Gmbh Procédé de traitement ou de prévention des troubles d système nerveux central avec des composants disposant d'un récepteur de benzodiazépine sélectif
EP2093218A1 (fr) * 2008-02-22 2009-08-26 Ruggero Fariello Imidazolidinones substitués d'arylalkyl
JP2014521713A (ja) 2011-08-12 2014-08-28 ベーリンガー インゲルハイム フェトメディカ ゲゼルシャフト ミット ベシュレンクテル ハフツング 味をマスキングした医薬組成物
US9820988B2 (en) 2014-03-24 2017-11-21 Boehringer Ingelheim Vetmedica Gmbh Treatment of epileptic disorders in feline animals
IT202100000782A1 (it) 2021-01-18 2022-07-18 Procos Spa Processo per la sintesi di imepitoina

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2251354A1 (de) 1971-10-21 1973-04-26 American Cyanamid Co Neue diuretica und mittel zur behandlung von hyperaldosteronismus
US4044021A (en) 1971-10-21 1977-08-23 American Cyanamid Company Tetrasubstituted imidazolidine diuretics useful in the treatment of hyperaldosteronism

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3932452A (en) * 1975-02-07 1976-01-13 Morton-Norwich Products, Inc. 1-Arylmethyl-2-imidazolidinones

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2251354A1 (de) 1971-10-21 1973-04-26 American Cyanamid Co Neue diuretica und mittel zur behandlung von hyperaldosteronismus
US4044021A (en) 1971-10-21 1977-08-23 American Cyanamid Company Tetrasubstituted imidazolidine diuretics useful in the treatment of hyperaldosteronism

Also Published As

Publication number Publication date
CA2184871C (fr) 2001-08-21
AU6737596A (en) 1997-03-27
LT98047A (en) 1998-10-26
UA46790C2 (uk) 2002-06-17
TR199800476T1 (xx) 1998-06-22
AU700602B2 (en) 1999-01-07
CA2184871A1 (fr) 1997-03-06
WO1997009314A1 (fr) 1997-03-13
CZ291839B6 (cs) 2003-06-18
ES2208758T3 (es) 2004-06-16
ZA967014B (en) 1997-08-18
EE03562B1 (et) 2001-12-17
EP0863880B1 (fr) 2003-11-19
PL188287B1 (pl) 2005-01-31
SK21698A3 (en) 1998-10-07
GEP20022652B (en) 2002-03-25
BG63917B1 (bg) 2003-06-30
DE59610827D1 (de) 2003-12-24
EP0863880A1 (fr) 1998-09-16
BG102287A (en) 1998-09-30
IL123333A (en) 2001-10-31
NO980906D0 (no) 1998-03-02
HK1015776A1 (en) 1999-10-22
PT863880E (pt) 2004-04-30
NZ315624A (en) 1998-11-25
ATE254606T1 (de) 2003-12-15
NO980906L (no) 1998-03-02
CN1200728A (zh) 1998-12-02
EA000535B1 (ru) 1999-10-28
EA199800271A1 (ru) 1998-10-29
LU92263I2 (fr) 2013-10-07
BR9610359A (pt) 1999-07-06
JPH11512101A (ja) 1999-10-19
HU225956B1 (en) 2008-01-28
DK0863880T3 (da) 2004-03-22
CZ66198A3 (cs) 1998-07-15
CN1103762C (zh) 2003-03-26
TW422838B (en) 2001-02-21
FR13C0049I1 (fr) 2013-09-27
EE9800063A (et) 1998-08-17
IL123333A0 (en) 1998-09-24
JP4030578B2 (ja) 2008-01-09
SK284868B6 (sk) 2006-01-05
FR13C0049I2 (fr) 2014-03-28
AR003502A1 (es) 1998-08-05
HUP9802941A2 (hu) 1999-09-28
HUP9802941A3 (en) 1999-10-28
PL325413A1 (en) 1998-07-20
NO313829B1 (no) 2002-12-09
MX9801742A (es) 1998-08-30
DE19532668A1 (de) 1997-03-06

Similar Documents

Publication Publication Date Title
US5236957A (en) N-phenylalkyl substituted α-amino carboxamide derivatives and process for their preparation
US4400394A (en) Benzylidene derivatives
FI62821B (fi) Foerfarande foer framstaellning av nya terapeutiskt anvaendbara hydroxamsyror
EP0734379B1 (fr) Derives de 2-arylalkenyl-azacycloalkanes ligands aux recepteurs sigma, leur procede de preparation et leur application en therapeutique
US4324787A (en) 2-Oxo-1-pyrrolidineacetic acid compounds and their medicinal use
PL194745B1 (pl) Podstawiony 2-benzyloamino-2-fenylo-acetamid, zawierająca go kompozycja farmaceutyczna i zastosowanie
LT4482B (lt) Nauji 1-aril(alkil)imidazolin-2-onai, turintys dipakeistą aminogrupė 4 padėtyje, pasižymintys antispazminiu veikimu, ir jų gavimo būdas
IE55872B1 (en) Derivatives of omega-amino acids,the preparation and utilisation thereof,and the compositions containing these derivatives
HU178652B (en) Process for producing pharmaceutically active 2-bracket-amino-butoxy-bracket closed stylbenes
FI69836B (fi) Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 4-fenyl-1,3-bensodiazepinderivat
Pavia et al. N, N-Disubstituted 6-alkoxy-2-pyridinamines as anticonvulsant agents
EP0475214B1 (fr) Dérivés de l'acide caféique et compositions pharmaceutiques les contenant
KR910003711B1 (ko) 2-(n-피롤리디노)-3-이소부톡시-n-치환된 페닐-n-벤질-프로필아민의 제조방법
HU190710B (en) Process for preparing 2-/4-piperazinyl/-4-phenyl-quinazoline derivatives
AU611978B2 (en) Araliphatic oxo(hydroxy) amines
SU906366A3 (ru) Способ получени гидрохлорида N-алкильных производных 1-фенил-2-амино-1,3-пропандиола
FI60863C (fi) Foerfarande foer framstaellning av nya bentshydryloxialkylaminderivat med foerlaengd antihistamineffekt
FR2507180A1 (fr) Nouvelles phenylalkylamines, leur preparation et leur application comme medicaments
US3963748A (en) 1-Phenyl-3-azacarbocyclic-ureas
LT4457B (lt) Nauji pasižymintys antispazminiu aktyvumu imidazolin-2,4-dionai, turintys orto-pakeistą aril(alkil)-radikalą 1 padėtyje, ir jų gavimo būdas
EP0663395A1 (fr) Dérivés de 3-(phénylalkylaminoalkyloxy)-5-phénylpyrazole, procédé et intermédiaires pour leur préparation et leur utilisation comme agent de réduction du rythme cardiaque
US4026938A (en) 1-Phenyl-3-azacarbocyclic-ureas
US4052382A (en) 1-phenyl-3-azacarbocyclic-ureas
DD301657A9 (de) Verfahren zur herstellung von zwischenprodukten fuer bis (benzylpyrrolidin)-dopanin-agonisten

Legal Events

Date Code Title Description
PC9A Transfer of patents

Owner name: ELBION AG, DE

Effective date: 20041130

PD9A Change of patent owner

Owner name: ELBION GMBH, , , DE

Effective date: 20071122

TC9A Change of representative

Owner name: ELBION GMBH, , , DE

MK9A Expiry of a patent

Effective date: 20160726