KR960005955B1 - 벤조[b]티오펜-5-일 유도체 및 이의 제조방법 - Google Patents

벤조[b]티오펜-5-일 유도체 및 이의 제조방법 Download PDF

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Publication number
KR960005955B1
KR960005955B1 KR1019930006106A KR930006106A KR960005955B1 KR 960005955 B1 KR960005955 B1 KR 960005955B1 KR 1019930006106 A KR1019930006106 A KR 1019930006106A KR 930006106 A KR930006106 A KR 930006106A KR 960005955 B1 KR960005955 B1 KR 960005955B1
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KR
South Korea
Prior art keywords
formula
compound
thiophen
benzo
optically active
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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KR1019930006106A
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English (en)
Korean (ko)
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KR930021632A (ko
Inventor
조지 나카노
노부히사 다야
히사아키 차키
데쓰오 야마후지
가이슈 모모노이
Original Assignee
도야마카가쿠코교 가부시키가이샤
나카노 가츠히코
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Publication of KR930021632A publication Critical patent/KR930021632A/ko
Application granted granted Critical
Publication of KR960005955B1 publication Critical patent/KR960005955B1/ko
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Saccharide Compounds (AREA)
  • Seasonings (AREA)
  • Bakery Products And Manufacturing Methods Therefor (AREA)
  • Furan Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Manufacture Of Macromolecular Shaped Articles (AREA)
KR1019930006106A 1992-04-13 1993-04-13 벤조[b]티오펜-5-일 유도체 및 이의 제조방법 Expired - Fee Related KR960005955B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP???? 1986-02-04
JP11974092 1992-04-13
JP92-119740 1992-04-13
JP5090934A JP2873898B2 (ja) 1992-04-13 1993-03-25 ベンゾ［ｂ］チオフェン−５−イル誘導体もしくはその光学活性体またはそれらの塩並びにそれらの製造法
JP93-090934 1993-03-25

Publications (2)

Publication Number Publication Date
KR930021632A KR930021632A (ko) 1993-11-22
KR960005955B1 true KR960005955B1 (ko) 1996-05-06

Family

ID=26432339

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019930006106A Expired - Fee Related KR960005955B1 (ko) 1992-04-13 1993-04-13 벤조[b]티오펜-5-일 유도체 및 이의 제조방법

Country Status (19)

Country Link
US (1) US5380878A (https=)
EP (1) EP0565965B1 (https=)
JP (1) JP2873898B2 (https=)
KR (1) KR960005955B1 (https=)
AT (1) ATE145204T1 (https=)
AU (1) AU643634B1 (https=)
BE (1) BE1006403A3 (https=)
CA (1) CA2093048C (https=)
CZ (2) CZ290421B6 (https=)
DE (1) DE69305904T2 (https=)
DK (1) DK0565965T3 (https=)
ES (1) ES2060545B1 (https=)
FR (1) FR2689890B1 (https=)
HU (1) HU213631B (https=)
IT (1) IT1261440B (https=)
NZ (1) NZ247301A (https=)
PL (1) PL172191B1 (https=)
RO (1) RO115445B1 (https=)
TW (1) TW232690B (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5606076A (en) * 1995-06-07 1997-02-25 Eli Lilly And Company Process for the synthesis of benzo[b]thiophenes
WO1997039740A1 (en) * 1996-04-22 1997-10-30 Toyama Chemical Co., Ltd. Patch containing 1,2-ethanediol derivatives or salts thereof
AU6519798A (en) * 1997-03-31 1998-10-22 Toyama Chemical Co. Ltd. Process for producing 2-(benzo{b}thiophen-5-yl)-2-hydroxyacetic acid derivatives, optically active compounds thereof, or salts of both
SK287673B6 (sk) * 1999-06-11 2011-05-06 Toyama Chemical Co., Ltd Derivát N-alkoxyalkyl-N,N-dialkylamínu, liečivo obsahujúce tento derivát a jeho použitie
KR100710564B1 (ko) * 2003-07-30 2007-04-24 에스케이 주식회사 연속 모사 이동층 흡착분리공정을 이용한 광학활성티오펜계 화합물의 분리방법

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57500147A (https=) * 1979-11-15 1982-01-28
EP0179383B1 (en) * 1984-10-25 1991-05-29 Hoechst-Roussel Pharmaceuticals Incorporated 9-amino-1,2,3,4-tetrahydroacridin-1-ol and related compounds, a process for their preparation and their use as medicaments
DK167393B1 (da) * 1985-12-30 1993-10-25 Roussel Uclaf 1-sulfonyl-2-oxo-pyrrolidinderivater, deres fremstilling og farmaceutiske praeparater med indhold deraf
IT1204494B (it) * 1986-03-28 1989-03-01 Roussel Maestretti Spa Derivati della 1-stirene solfonil 2-osso 5-alcossi pirrolidina,loro procedimento di preparazione e loro applicazione come farmaci
US4791107A (en) * 1986-07-16 1988-12-13 Hoechst-Roussel Pharmaceuticals, Inc. Memory enhancing and analgesic 1,2,3,3A,8,8A-hexahydro-3A,8 (and) 1,3A,8)-di(and tri)methylpyrrolo(2,3-B)indoles, compositions and use
JPH0813741B2 (ja) * 1987-08-10 1996-02-14 協和醗酵工業株式会社 抗痴呆剤
US4877790A (en) * 1987-12-15 1989-10-31 Kanebo Limited Quinazoline derivative, processes for its production, and cerebral dysfunction remedying agent comprising it as active ingredient
US4859666A (en) * 1988-07-06 1989-08-22 Bristol-Myers Company THAZ derivatives for enhancement of cerebral function
JPH085790B2 (ja) * 1988-11-11 1996-01-24 杏林製薬株式会社 記憶障害改善薬
NZ232493A (en) * 1989-02-14 1992-06-25 Toyama Chemical Co Ltd Aryl- or heterocyclyl-substituted 1,2-ethanediol derivatives and pharmaceutical compositions
JP3044055B2 (ja) * 1990-08-09 2000-05-22 富山化学工業株式会社 １，２―エタンジオール誘導体およびその塩

Also Published As

Publication number Publication date
ITRM930232A0 (it) 1993-04-09
EP0565965A3 (https=) 1994-03-02
CZ61093A3 (en) 1993-12-15
PL172191B1 (pl) 1997-08-29
JP2873898B2 (ja) 1999-03-24
ES2060545B1 (es) 1997-12-01
IT1261440B (it) 1996-05-23
ES2060545A1 (es) 1994-11-16
KR930021632A (ko) 1993-11-22
BE1006403A3 (fr) 1994-08-16
ITRM930232A1 (it) 1994-10-09
PL298494A1 (en) 1993-12-27
DE69305904D1 (de) 1996-12-19
EP0565965A2 (en) 1993-10-20
US5380878A (en) 1995-01-10
AU643634B1 (en) 1993-11-18
HU213631B (en) 1997-08-28
EP0565965B1 (en) 1996-11-13
CZ290864B6 (cs) 2002-11-13
DE69305904T2 (de) 1997-03-13
CA2093048A1 (en) 1993-10-14
ATE145204T1 (de) 1996-11-15
DK0565965T3 (da) 1997-04-21
NZ247301A (en) 1994-07-26
RO115445B1 (ro) 2000-02-28
FR2689890B1 (fr) 1995-01-06
TW232690B (https=) 1994-10-21
JPH069615A (ja) 1994-01-18
HUT64319A (en) 1993-12-28
CZ290421B6 (cs) 2002-07-17
CA2093048C (en) 1996-10-08
HU9301052D0 (en) 1993-07-28
FR2689890A1 (fr) 1993-10-15

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