DE69305904D1 - Benzo(b)Thiophen-5-Ylderivat und Verfahren zu seiner Herstellung - Google Patents
Benzo(b)Thiophen-5-Ylderivat und Verfahren zu seiner HerstellungInfo
- Publication number
- DE69305904D1 DE69305904D1 DE69305904T DE69305904T DE69305904D1 DE 69305904 D1 DE69305904 D1 DE 69305904D1 DE 69305904 T DE69305904 T DE 69305904T DE 69305904 T DE69305904 T DE 69305904T DE 69305904 D1 DE69305904 D1 DE 69305904D1
- Authority
- DE
- Germany
- Prior art keywords
- benzo
- protecting
- thiophen
- formula
- optically active
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Bakery Products And Manufacturing Methods Therefor (AREA)
- Seasonings (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Saccharide Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Manufacture Of Macromolecular Shaped Articles (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP11974092 | 1992-04-13 | ||
JP5090934A JP2873898B2 (ja) | 1992-04-13 | 1993-03-25 | ベンゾ[b]チオフェン−5−イル誘導体もしくはその光学活性体またはそれらの塩並びにそれらの製造法 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69305904D1 true DE69305904D1 (de) | 1996-12-19 |
DE69305904T2 DE69305904T2 (de) | 1997-03-13 |
Family
ID=26432339
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69305904T Expired - Fee Related DE69305904T2 (de) | 1992-04-13 | 1993-04-01 | Benzo(b)Thiophen-5-Ylderivat und Verfahren zu seiner Herstellung |
Country Status (19)
Country | Link |
---|---|
US (1) | US5380878A (de) |
EP (1) | EP0565965B1 (de) |
JP (1) | JP2873898B2 (de) |
KR (1) | KR960005955B1 (de) |
AT (1) | ATE145204T1 (de) |
AU (1) | AU643634B1 (de) |
BE (1) | BE1006403A3 (de) |
CA (1) | CA2093048C (de) |
CZ (2) | CZ290421B6 (de) |
DE (1) | DE69305904T2 (de) |
DK (1) | DK0565965T3 (de) |
ES (1) | ES2060545B1 (de) |
FR (1) | FR2689890B1 (de) |
HU (1) | HU213631B (de) |
IT (1) | IT1261440B (de) |
NZ (1) | NZ247301A (de) |
PL (1) | PL172191B1 (de) |
RO (1) | RO115445B1 (de) |
TW (1) | TW232690B (de) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5606076A (en) * | 1995-06-07 | 1997-02-25 | Eli Lilly And Company | Process for the synthesis of benzo[b]thiophenes |
AU2576797A (en) * | 1996-04-22 | 1997-11-12 | Toyama Chemical Co. Ltd. | Patch containing 1,2-ethanediol derivatives or salts thereof |
JP4245668B2 (ja) * | 1997-03-31 | 2009-03-25 | 富山化学工業株式会社 | 2−(ベンゾ〔b〕チオフェン−5−イル)−2−ヒドロキシ酢酸誘導体もしくはその光学活性体またはそれらの塩の製造法 |
DK1186594T3 (da) * | 1999-06-11 | 2009-09-14 | Toyama Chemical Co Ltd | N-alkoxylkyl-N,N-dialkylamin-derivater eller salte deraf og midler mod neurodegenerative sygdomme, som indeholder disse |
KR100710564B1 (ko) * | 2003-07-30 | 2007-04-24 | 에스케이 주식회사 | 연속 모사 이동층 흡착분리공정을 이용한 광학활성티오펜계 화합물의 분리방법 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4372970A (en) * | 1979-11-15 | 1983-02-08 | Shell Internationale Research Maatschappij B.V. | Benzofuran acetic acid esters and their arthropocidal compositions |
ATE63903T1 (de) * | 1984-10-25 | 1991-06-15 | Hoechst Roussel Pharma | 9-amino-1,2,3,4-tetrahydroacridin-1-ol und verwandte verbindungen, verfahren zu ihrer herstellung und verwendung als arzneimittel. |
DK167393B1 (da) * | 1985-12-30 | 1993-10-25 | Roussel Uclaf | 1-sulfonyl-2-oxo-pyrrolidinderivater, deres fremstilling og farmaceutiske praeparater med indhold deraf |
IT1204494B (it) * | 1986-03-28 | 1989-03-01 | Roussel Maestretti Spa | Derivati della 1-stirene solfonil 2-osso 5-alcossi pirrolidina,loro procedimento di preparazione e loro applicazione come farmaci |
US4791107A (en) * | 1986-07-16 | 1988-12-13 | Hoechst-Roussel Pharmaceuticals, Inc. | Memory enhancing and analgesic 1,2,3,3A,8,8A-hexahydro-3A,8 (and) 1,3A,8)-di(and tri)methylpyrrolo(2,3-B)indoles, compositions and use |
JPH0813741B2 (ja) * | 1987-08-10 | 1996-02-14 | 協和醗酵工業株式会社 | 抗痴呆剤 |
US4877790A (en) * | 1987-12-15 | 1989-10-31 | Kanebo Limited | Quinazoline derivative, processes for its production, and cerebral dysfunction remedying agent comprising it as active ingredient |
US4859666A (en) * | 1988-07-06 | 1989-08-22 | Bristol-Myers Company | THAZ derivatives for enhancement of cerebral function |
JPH085790B2 (ja) * | 1988-11-11 | 1996-01-24 | 杏林製薬株式会社 | 記憶障害改善薬 |
NZ232493A (en) * | 1989-02-14 | 1992-06-25 | Toyama Chemical Co Ltd | Aryl- or heterocyclyl-substituted 1,2-ethanediol derivatives and pharmaceutical compositions |
JP3044055B2 (ja) * | 1990-08-09 | 2000-05-22 | 富山化学工業株式会社 | 1,2―エタンジオール誘導体およびその塩 |
-
1993
- 1993-03-25 JP JP5090934A patent/JP2873898B2/ja not_active Expired - Fee Related
- 1993-03-31 CA CA002093048A patent/CA2093048C/en not_active Expired - Fee Related
- 1993-03-31 NZ NZ24730193A patent/NZ247301A/en not_active IP Right Cessation
- 1993-04-01 DK DK93105441.5T patent/DK0565965T3/da active
- 1993-04-01 DE DE69305904T patent/DE69305904T2/de not_active Expired - Fee Related
- 1993-04-01 AT AT93105441T patent/ATE145204T1/de not_active IP Right Cessation
- 1993-04-01 EP EP93105441A patent/EP0565965B1/de not_active Expired - Lifetime
- 1993-04-02 AU AU35659/93A patent/AU643634B1/en not_active Ceased
- 1993-04-07 ES ES09300733A patent/ES2060545B1/es not_active Expired - Fee Related
- 1993-04-08 TW TW082102584A patent/TW232690B/zh active
- 1993-04-09 CZ CZ1993610A patent/CZ290421B6/cs not_active IP Right Cessation
- 1993-04-09 HU HU9301052A patent/HU213631B/hu not_active IP Right Cessation
- 1993-04-09 FR FR9304226A patent/FR2689890B1/fr not_active Expired - Lifetime
- 1993-04-09 IT ITRM930232A patent/IT1261440B/it active IP Right Grant
- 1993-04-12 RO RO93-00505A patent/RO115445B1/ro unknown
- 1993-04-13 KR KR1019930006106A patent/KR960005955B1/ko not_active IP Right Cessation
- 1993-04-13 BE BE9300363A patent/BE1006403A3/fr not_active IP Right Cessation
- 1993-04-13 PL PL93298494A patent/PL172191B1/pl not_active IP Right Cessation
-
1994
- 1994-03-29 US US08/217,960 patent/US5380878A/en not_active Expired - Lifetime
- 1994-08-09 CZ CZ19941925A patent/CZ290864B6/cs not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
BE1006403A3 (fr) | 1994-08-16 |
HU9301052D0 (en) | 1993-07-28 |
PL298494A1 (en) | 1993-12-27 |
RO115445B1 (ro) | 2000-02-28 |
CZ61093A3 (en) | 1993-12-15 |
TW232690B (de) | 1994-10-21 |
CA2093048A1 (en) | 1993-10-14 |
NZ247301A (en) | 1994-07-26 |
FR2689890B1 (fr) | 1995-01-06 |
CA2093048C (en) | 1996-10-08 |
ES2060545B1 (es) | 1997-12-01 |
CZ290864B6 (cs) | 2002-11-13 |
ES2060545A1 (es) | 1994-11-16 |
DK0565965T3 (da) | 1997-04-21 |
US5380878A (en) | 1995-01-10 |
AU643634B1 (en) | 1993-11-18 |
KR930021632A (ko) | 1993-11-22 |
JPH069615A (ja) | 1994-01-18 |
EP0565965A2 (de) | 1993-10-20 |
HU213631B (en) | 1997-08-28 |
EP0565965A3 (de) | 1994-03-02 |
DE69305904T2 (de) | 1997-03-13 |
FR2689890A1 (fr) | 1993-10-15 |
ITRM930232A0 (it) | 1993-04-09 |
KR960005955B1 (ko) | 1996-05-06 |
ITRM930232A1 (it) | 1994-10-09 |
IT1261440B (it) | 1996-05-23 |
CZ290421B6 (cs) | 2002-07-17 |
HUT64319A (en) | 1993-12-28 |
PL172191B1 (pl) | 1997-08-29 |
EP0565965B1 (de) | 1996-11-13 |
ATE145204T1 (de) | 1996-11-15 |
JP2873898B2 (ja) | 1999-03-24 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE147734T1 (de) | Neues verfahren zur veresterung von baccatin iii und 10-deacetylbaccatin iii | |
FI880742A (fi) | Menetelmä uusien, terapeuttisesti käyttökelpoisten, 7-asemassa substituoitujen 19-norsteroidien valmistamiseksi | |
KR920006358A (ko) | 1-메틸카르바펜엠 유도체 및 그의 제조방법 | |
ES8801618A1 (es) | Un procedimiento para preparar derivados de arilciclobutilalquilamina | |
DE69305904D1 (de) | Benzo(b)Thiophen-5-Ylderivat und Verfahren zu seiner Herstellung | |
DE69229402T2 (de) | Verfahren zur hestellung von pharmazeutisch aktiven thiazolidin oder oxazolidin verbindungen unter verwendung einer hefe-reduktase | |
AR248128A1 (es) | Procedimiento para preparar esteres aromaticos sensibles o insensibles a oxidantes, utiles como inhibidores de la elastasa neutrofilica humana. | |
FI102679B1 (fi) | Menetelmä uusien terapeuttisesti käyttökelpoisten sertindoli-prodrugjohdannaisten valmistamiseksi | |
DE69103087D1 (de) | N-substituierte Trifluormethylphenyltetrahydropyridine, Verfahren zur Herstellung, Zwischenprodukte, sowie Arzneimittel, die solche enthalten. | |
KR960004336A (ko) | 3-(4-아미노 에톡시-벤조일) 벤조[b]- 티오펜의 개선된 제조방법 | |
DE68903405T2 (de) | Verfahren zur herstellung von 2-alpha-methyl-2-beta-(1,2,3-triazol-1-yl)methylpenam-3-alpha-carbonsaeurederivaten. | |
PT87219A (pt) | Process for preparing sulfonyldecahydro-8h-isoquino ]2,1-g" ]1,6" naphthyridines optical isomers thereof and related compounds | |
FI940999A0 (fi) | Piperidin-2-alkyylikarboksylaattien entsymaattinen toisiintuminen ja saatujen yhdisteiden käyttö synteesin välituotteina | |
GB1433131A (en) | Penicillins | |
FR2609603B1 (fr) | Agents edulcorants derives des acides guanidinoacetique et ethanamidinoacetique, procede pour edulcorer des produits divers, et compositions contenant de tels agents edulcorants | |
DE69123009T2 (de) | Verfahren zur Herstellung optisch aktiver 3-Hydroxybutan-Derivate | |
ATE384706T1 (de) | Verfahren zur kontinuierlichen herstellung von substituierten oxazolen | |
DK0663901T3 (da) | Fremgangsmåde til stereoselektiv fremstilling af et derivat af beta-phenylisoserin samt anvendelse deraf til fremstilling af taxanderivater | |
DE69123402T2 (de) | Verfahren zur Herstellung optisch aktiver Alpha-Hydroxyalkenderivate | |
HU905000D0 (en) | Process for producing compounds suitable for treatment of gastric ulcer | |
DE69306760D1 (de) | Säureanhydride, ihre herstellung und ihre verwendung | |
ATE132146T1 (de) | Verfahren zur herstellung von 6-(3- dimethylaminopropionyl)forskolin | |
DE69333240D1 (de) | Verfahren zur herstellung von enantiomerreinen fluorierten epoxychromanen | |
FI942167A0 (fi) | Optisesti aktiivinen 1-fenyylipyrrolidonijohdannainen, välituote sen valmistamiseksi ja menetelmä molempien valmistamiseksi | |
HUT49838A (en) | Process for producing optical isomers of 2-(3,4-disubstituted phenyl)-3-methylbutyric acids and their esters |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |