FI940999A0 - Piperidin-2-alkyylikarboksylaattien entsymaattinen toisiintuminen ja saatujen yhdisteiden käyttö synteesin välituotteina - Google Patents
Piperidin-2-alkyylikarboksylaattien entsymaattinen toisiintuminen ja saatujen yhdisteiden käyttö synteesin välituotteinaInfo
- Publication number
- FI940999A0 FI940999A0 FI940999A FI940999A FI940999A0 FI 940999 A0 FI940999 A0 FI 940999A0 FI 940999 A FI940999 A FI 940999A FI 940999 A FI940999 A FI 940999A FI 940999 A0 FI940999 A0 FI 940999A0
- Authority
- FI
- Finland
- Prior art keywords
- piperidine
- trans
- alkyl carboxylate
- alkyl
- enzymatic rearrangement
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
- C12P41/005—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of carboxylic acid groups in the enantiomers or the inverse reaction
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/10—Nitrogen as only ring hetero atom
- C12P17/12—Nitrogen as only ring hetero atom containing a six-membered hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hydrogenated Pyridines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9302434A FR2702220B1 (fr) | 1993-03-03 | 1993-03-03 | Dédoublement enzymatique de dérivés de 4-alkyl-2-pipéridine-carboxylate et utilisation des composés obtenus, comme intermédiaires de synthèse. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI940999A0 true FI940999A0 (fi) | 1994-03-02 |
| FI940999A FI940999A (fi) | 1994-09-04 |
Family
ID=9444600
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI940999A FI940999A (fi) | 1993-03-03 | 1994-03-02 | Piperidin-2-alkyylikarboksylaattien entsymaattinen toisiintuminen ja saatujen yhdisteiden käyttö synteesin välituotteina |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0614986B1 (fi) |
| JP (1) | JPH06296498A (fi) |
| KR (1) | KR940021737A (fi) |
| CN (1) | CN1100143A (fi) |
| AT (1) | ATE182368T1 (fi) |
| CA (1) | CA2116833A1 (fi) |
| DE (1) | DE69419547D1 (fi) |
| FI (1) | FI940999A (fi) |
| FR (1) | FR2702220B1 (fi) |
| IL (1) | IL108829A (fi) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2718439B3 (fr) * | 1994-04-12 | 1996-02-09 | Synthelabo | Dérivés de l'acide pipécolique, leur préparation et leur utilisation comme intermédiaires de synthèse. |
| US5840733A (en) * | 1996-07-01 | 1998-11-24 | Redcell, Canada, Inc. | Methods and compositions for producing novel conjugates of thrombin inhibitors and endogenous carriers resulting in anti-thrombins with extended lifetimes |
| GB9924882D0 (en) * | 1999-10-20 | 1999-12-22 | Smithkline Beecham Plc | Novel process |
| FR2804682B1 (fr) * | 2000-02-09 | 2002-05-03 | Rhodia Chimie Sa | Procede de preparation diastereoselective de piperidines fonctionnalisees en positions 2 et 4 utilisables comme intermediaires de synthese |
| WO2002053536A1 (en) * | 2000-12-29 | 2002-07-11 | Chirotech Technology Ltd. | Chiral scaffolds and their preparation |
| CN101712645B (zh) * | 2009-11-20 | 2013-08-28 | 重庆威尔德·浩瑞医药化工有限公司 | 一种(2r,4r)-4-甲基-2-哌啶甲酸的制备方法 |
| CN102952065A (zh) * | 2011-08-24 | 2013-03-06 | 重庆华邦胜凯制药有限公司 | 一种拆分顺式2,3-吡啶二甲酸酯的方法 |
| CN102719512B (zh) * | 2012-06-21 | 2014-06-11 | 浙江工业大学 | 一种r-2-（4-羟基苯氧基）丙酸酯的制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE48623B1 (en) * | 1978-08-31 | 1985-03-20 | Mitsubishi Chem Ind | Alpha-(n-arylsulfonyl-l-argininamides,processes for their preparation and pharmaceutical compositions containing these substances |
| DE3379266D1 (en) * | 1983-08-01 | 1989-04-06 | Astra Laekemedel Ab | L-n-n-propylpipecolic acid-2,6-xylidide and method for preparing the same |
| JPH0641075A (ja) * | 1990-09-01 | 1994-02-15 | Kazuo Achinami | 新規な１，４−ジヒドロピリジン化合物及びその製造方法 |
-
1993
- 1993-03-03 FR FR9302434A patent/FR2702220B1/fr not_active Expired - Fee Related
-
1994
- 1994-02-23 EP EP94400381A patent/EP0614986B1/fr not_active Expired - Lifetime
- 1994-02-23 AT AT94400381T patent/ATE182368T1/de not_active IP Right Cessation
- 1994-02-23 DE DE69419547T patent/DE69419547D1/de not_active Expired - Lifetime
- 1994-03-02 CN CN94102250A patent/CN1100143A/zh active Pending
- 1994-03-02 KR KR1019940004000A patent/KR940021737A/ko not_active Application Discontinuation
- 1994-03-02 FI FI940999A patent/FI940999A/fi unknown
- 1994-03-02 CA CA002116833A patent/CA2116833A1/fr not_active Abandoned
- 1994-03-02 IL IL10882994A patent/IL108829A/en active IP Right Grant
- 1994-03-02 JP JP6032202A patent/JPH06296498A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| FR2702220A1 (fr) | 1994-09-09 |
| EP0614986B1 (fr) | 1999-07-21 |
| IL108829A0 (en) | 1994-06-24 |
| CN1100143A (zh) | 1995-03-15 |
| IL108829A (en) | 1999-03-12 |
| JPH06296498A (ja) | 1994-10-25 |
| DE69419547D1 (de) | 1999-08-26 |
| EP0614986A1 (fr) | 1994-09-14 |
| FI940999A (fi) | 1994-09-04 |
| ATE182368T1 (de) | 1999-08-15 |
| CA2116833A1 (fr) | 1994-09-04 |
| FR2702220B1 (fr) | 1995-05-12 |
| KR940021737A (ko) | 1994-10-19 |
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