DE50212728D1 - Verfahren zur herstellung von 2-azetidinonderivaten - Google Patents
Verfahren zur herstellung von 2-azetidinonderivatenInfo
- Publication number
- DE50212728D1 DE50212728D1 DE50212728T DE50212728T DE50212728D1 DE 50212728 D1 DE50212728 D1 DE 50212728D1 DE 50212728 T DE50212728 T DE 50212728T DE 50212728 T DE50212728 T DE 50212728T DE 50212728 D1 DE50212728 D1 DE 50212728D1
- Authority
- DE
- Germany
- Prior art keywords
- preparation
- following formula
- compound represented
- azetidinone derivatives
- azetidinone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/10—Nitrogen as only ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001063840 | 2001-03-07 | ||
| PCT/JP2002/001969 WO2002070512A1 (fr) | 2001-03-07 | 2002-03-04 | Procede de fabrication d'un derive d'azetidinone-2 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE50212728D1 true DE50212728D1 (de) | 2008-10-16 |
Family
ID=18922762
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE50212728T Expired - Lifetime DE50212728D1 (de) | 2001-03-07 | 2002-03-04 | Verfahren zur herstellung von 2-azetidinonderivaten |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US7126003B2 (de) |
| EP (1) | EP1375495B1 (de) |
| JP (1) | JP4142444B2 (de) |
| KR (1) | KR100851515B1 (de) |
| CN (1) | CN1266148C (de) |
| AT (1) | ATE407130T1 (de) |
| DE (1) | DE50212728D1 (de) |
| ES (1) | ES2311591T3 (de) |
| HK (1) | HK1058668A1 (de) |
| MY (1) | MY139322A (de) |
| NO (1) | NO20033917L (de) |
| TW (1) | TWI311135B (de) |
| WO (1) | WO2002070512A1 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1457492B1 (de) * | 2001-11-29 | 2008-01-02 | Daiichi Sankyo Company, Limited | Kristalle von taxanderivaten und verfahren zu deren herstellung |
| JP4958785B2 (ja) | 2004-09-20 | 2012-06-20 | ゼノン・ファーマシューティカルズ・インコーポレイテッド | 複素環誘導体およびステアロイル−ＣｏＡデサチュラーゼインヒビターとしてのそれらの使用 |
| AU2005286648A1 (en) | 2004-09-20 | 2006-03-30 | Xenon Pharmaceuticals Inc. | Heterocyclic derivatives and their use as stearoyl-CoA desaturase inhibitors |
| CN101084211A (zh) | 2004-09-20 | 2007-12-05 | 泽农医药公司 | 杂环衍生物及其作为治疗剂的用途 |
| MX2007003318A (es) | 2004-09-20 | 2007-05-18 | Xenon Pharmaceuticals Inc | Derivados heterociclicos y su uso como agentes terapeuticos. |
| AR051094A1 (es) | 2004-09-20 | 2006-12-20 | Xenon Pharmaceuticals Inc | Derivados heterociclicos y su uso como inhibidores de la estearoil-coa desaturasa |
| AU2005286728A1 (en) | 2004-09-20 | 2006-03-30 | Xenon Pharmaceuticals Inc. | Heterocyclic derivatives and their use as mediators of stearoyl-CoA desaturase |
| US7767677B2 (en) | 2004-09-20 | 2010-08-03 | Xenon Pharmaceuticals Inc. | Heterocyclic derivatives and their use as stearoyl-CoA desaturase inhibitors |
| WO2007130075A1 (en) | 2005-06-03 | 2007-11-15 | Xenon Pharmaceuticals Inc. | Aminothiazole derivatives as human stearoyl-coa desaturase inhibitors |
| CN100494204C (zh) * | 2006-01-12 | 2009-06-03 | 上海交通大学 | (1’r,3r,4r)-4-乙酸基-3-（1-叔丁基二甲基硅氧基乙基）氮杂环丁烷-2-酮的氧化合成方法 |
| US8697892B2 (en) | 2010-06-30 | 2014-04-15 | Gfv, Llc | Taxane compounds, compositions and methods |
| US8785669B2 (en) | 2010-06-30 | 2014-07-22 | Gfv, Llc | Taxane compounds, compositions and methods |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0679559B2 (ja) * | 1985-06-06 | 1994-10-12 | 三共株式会社 | 光学活性アゼチジノン誘導体の製法 |
| ES2230790T3 (es) | 1992-01-15 | 2005-05-01 | E.R. SQUIBB & SONS, INC. | Procedimientos enzimaticos para la resolucion de mezclas enantiomericas de compuestos utiles como intermedios en la preparacion de taxanos. |
| FR2688499B1 (fr) * | 1992-03-10 | 1994-05-06 | Rhone Poulenc Rorer Sa | Procede de preparation de la beta-phenylisoserine et de ses analogues. |
| EP0582469A2 (de) * | 1992-08-06 | 1994-02-09 | Wisconsin Alumni Research Foundation | Verfahren zur Herstellung von Taxol-Typ-Verbindungen vom Beta-Laktam-Vorläufer |
| TW397866B (en) * | 1993-07-14 | 2000-07-11 | Bristol Myers Squibb Co | Enzymatic processes for the resolution of enantiomeric mixtures of compounds useful as intermediates in the preparation of taxanes |
| JP3703519B2 (ja) * | 1994-05-31 | 2005-10-05 | 株式会社クラレ | 光学活性体の製造方法 |
| JP2779386B2 (ja) | 1995-11-01 | 1998-07-23 | 株式会社カンキョー | 全熱交換換気装置 |
| DE19605024A1 (de) | 1996-01-31 | 1997-08-07 | Schering Ag | Neue selektive Taxane, Verfahren zu ihrer Herstellung und ihre pharmazeutische Verwendung |
| EP0933360A1 (de) * | 1997-12-22 | 1999-08-04 | Pharmachemie B.V. | Synthese von Beta-lactamen |
| US6677456B2 (en) * | 1999-10-15 | 2004-01-13 | Daiichi Pharmaceutical Co., Ltd. | Pentacyclic taxan compound |
| US6548293B1 (en) * | 1999-10-18 | 2003-04-15 | Fsu Research Foundation, Inc. | Enzymatic process for the resolution of enantiomeric mixtures of β-lactams |
-
2002
- 2002-03-04 US US10/469,918 patent/US7126003B2/en not_active Expired - Lifetime
- 2002-03-04 WO PCT/JP2002/001969 patent/WO2002070512A1/ja active IP Right Grant
- 2002-03-04 ES ES02705071T patent/ES2311591T3/es not_active Expired - Lifetime
- 2002-03-04 KR KR1020037011670A patent/KR100851515B1/ko not_active IP Right Cessation
- 2002-03-04 JP JP2002569832A patent/JP4142444B2/ja not_active Expired - Lifetime
- 2002-03-04 DE DE50212728T patent/DE50212728D1/de not_active Expired - Lifetime
- 2002-03-04 CN CNB028093550A patent/CN1266148C/zh not_active Expired - Fee Related
- 2002-03-04 AT AT02705071T patent/ATE407130T1/de not_active IP Right Cessation
- 2002-03-04 EP EP02705071A patent/EP1375495B1/de not_active Expired - Lifetime
- 2002-03-07 TW TW091104253A patent/TWI311135B/zh not_active IP Right Cessation
- 2002-03-07 MY MYPI20020818A patent/MY139322A/en unknown
-
2003
- 2003-09-04 NO NO20033917A patent/NO20033917L/no not_active Application Discontinuation
-
2004
- 2004-02-26 HK HK04101387A patent/HK1058668A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CN1266148C (zh) | 2006-07-26 |
| US20040072309A1 (en) | 2004-04-15 |
| ATE407130T1 (de) | 2008-09-15 |
| US7126003B2 (en) | 2006-10-24 |
| HK1058668A1 (en) | 2004-05-28 |
| CN1507443A (zh) | 2004-06-23 |
| EP1375495A4 (de) | 2005-03-09 |
| ES2311591T3 (es) | 2009-02-16 |
| NO20033917D0 (no) | 2003-09-04 |
| KR20030080072A (ko) | 2003-10-10 |
| WO2002070512A1 (fr) | 2002-09-12 |
| NO20033917L (no) | 2003-10-31 |
| KR100851515B1 (ko) | 2008-08-11 |
| EP1375495B1 (de) | 2008-09-03 |
| MY139322A (en) | 2009-09-30 |
| EP1375495A1 (de) | 2004-01-02 |
| JP4142444B2 (ja) | 2008-09-03 |
| JPWO2002070512A1 (ja) | 2004-07-02 |
| TWI311135B (en) | 2009-06-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |