DE68903405T2 - Verfahren zur herstellung von 2-alpha-methyl-2-beta-(1,2,3-triazol-1-yl)methylpenam-3-alpha-carbonsaeurederivaten. - Google Patents

Verfahren zur herstellung von 2-alpha-methyl-2-beta-(1,2,3-triazol-1-yl)methylpenam-3-alpha-carbonsaeurederivaten.

Info

Publication number
DE68903405T2
DE68903405T2 DE8989301926T DE68903405T DE68903405T2 DE 68903405 T2 DE68903405 T2 DE 68903405T2 DE 8989301926 T DE8989301926 T DE 8989301926T DE 68903405 T DE68903405 T DE 68903405T DE 68903405 T2 DE68903405 T2 DE 68903405T2
Authority
DE
Germany
Prior art keywords
alpha
hydrogen
methylpenam
triazol
beta
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8989301926T
Other languages
English (en)
Other versions
DE68903405D1 (de
Inventor
Sigeru Torii
Hideo Tanaka
Motoaki Tanaka
Shozo Yamada
Akira Nakai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Chemical Co Ltd
Taiho Pharmaceutical Co Ltd
Original Assignee
Otsuka Chemical Co Ltd
Taiho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Chemical Co Ltd, Taiho Pharmaceutical Co Ltd filed Critical Otsuka Chemical Co Ltd
Publication of DE68903405D1 publication Critical patent/DE68903405D1/de
Application granted granted Critical
Publication of DE68903405T2 publication Critical patent/DE68903405T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/04—Preparation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE8989301926T 1988-03-01 1989-02-27 Verfahren zur herstellung von 2-alpha-methyl-2-beta-(1,2,3-triazol-1-yl)methylpenam-3-alpha-carbonsaeurederivaten. Expired - Lifetime DE68903405T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP63049039A JP2602685B2 (ja) 1988-03-01 1988-03-01 ２α−メチル−２β―（１，２，３−トリアゾール−１−イル）メチルペナム−３α−カルボン酸誘導体の製造法

Publications (2)

Publication Number Publication Date
DE68903405D1 DE68903405D1 (de) 1992-12-17
DE68903405T2 true DE68903405T2 (de) 1993-03-25

Family

ID=12819943

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8989301926T Expired - Lifetime DE68903405T2 (de) 1988-03-01 1989-02-27 Verfahren zur herstellung von 2-alpha-methyl-2-beta-(1,2,3-triazol-1-yl)methylpenam-3-alpha-carbonsaeurederivaten.

Country Status (11)

Country Link
US (1) US4895941A (de)
EP (1) EP0331395B1 (de)
JP (1) JP2602685B2 (de)
KR (1) KR900009138B1 (de)
CN (1) CN1022835C (de)
AT (1) ATE82292T1 (de)
AU (1) AU600404B2 (de)
CA (1) CA1339125C (de)
DE (1) DE68903405T2 (de)
ES (1) ES2044088T3 (de)
GR (1) GR3006640T3 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3743822B2 (ja) * 2000-08-11 2006-02-08 大塚化学ホールディングス株式会社 ペニシリン結晶及びその製造法
JP3306473B1 (ja) * 2001-05-01 2002-07-24 大塚化学株式会社 β−ラクタム化合物の無水結晶及びその製造法
KR100431052B1 (ko) * 2001-10-08 2004-05-12 주식회사 네오텍리서치 표면 굴곡에 의하여 형성된 다중 영역 효과를 가지는 액정표시 장치
RU2284329C2 (ru) * 2002-06-07 2006-09-27 Окид Кемикалз Энд Фармасьютикалз Лимитед Способ получения производных пенама из производных цефама
TW200519119A (en) * 2003-10-10 2005-06-16 Otsuka Chemical Co Ltd PENAM crystal and process for producing the same
US20060173177A1 (en) 2005-01-28 2006-08-03 Gego Csaba L Process for preparation of penam derivatives
CN102020663B (zh) * 2010-11-24 2013-04-03 山东鑫泉医药有限公司 一种他唑巴坦的合成方法
EP3626721B1 (de) * 2018-07-31 2023-09-06 Paolo Bonomi Synthese von ester- und amid-derivaten von beta-lactam-kernen
CN114031629A (zh) * 2021-12-10 2022-02-11 山东安舜制药有限公司 一种合成他唑巴坦中间体的方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2162185B (en) * 1982-04-08 1986-07-30 Erba Farmitalia New process for preparation of substituted penem derivatives
JPS58225091A (ja) * 1982-06-21 1983-12-27 Taiho Yakuhin Kogyo Kk ペニシリン誘導体及びその製造法
US4562073A (en) * 1982-12-24 1985-12-31 Taiho Pharmaceutical Company Limited Penicillin derivatives
US4496484A (en) * 1983-04-22 1985-01-29 Taiho Pharmaceutical Company, Limited Penicillin derivatives
CA1239392A (en) * 1983-10-13 1988-07-19 Shigeru Yamabe Penicillin derivatives and process for preparing the same
GB8518422D0 (en) * 1985-07-22 1985-08-29 Beecham Group Plc Compounds
US4891369A (en) * 1986-12-03 1990-01-02 Taiho Pharmaceutical Company, Limited 2β-Substituted-methylpenicillanic acid derivatives, and salts and esters thereof

Also Published As

Publication number Publication date
AU3029189A (en) 1989-09-07
KR900009138B1 (ko) 1990-12-22
KR890014553A (ko) 1989-10-24
DE68903405D1 (de) 1992-12-17
GR3006640T3 (de) 1993-06-30
CN1037514A (zh) 1989-11-29
AU600404B2 (en) 1990-08-09
CA1339125C (en) 1997-07-29
JPH0285290A (ja) 1990-03-26
ATE82292T1 (de) 1992-11-15
EP0331395A1 (de) 1989-09-06
ES2044088T3 (es) 1994-01-01
CN1022835C (zh) 1993-11-24
JP2602685B2 (ja) 1997-04-23
US4895941A (en) 1990-01-23
EP0331395B1 (de) 1992-11-11

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Free format text: BARZ, P., DIPL.-CHEM. DR.RER.NAT., PAT.-ANW., 80803 MUENCHEN