DK0663901T3 - Fremgangsmåde til stereoselektiv fremstilling af et derivat af beta-phenylisoserin samt anvendelse deraf til fremstilling af taxanderivater - Google Patents
Fremgangsmåde til stereoselektiv fremstilling af et derivat af beta-phenylisoserin samt anvendelse deraf til fremstilling af taxanderivaterInfo
- Publication number
- DK0663901T3 DK0663901T3 DK93921981.2T DK93921981T DK0663901T3 DK 0663901 T3 DK0663901 T3 DK 0663901T3 DK 93921981 T DK93921981 T DK 93921981T DK 0663901 T3 DK0663901 T3 DK 0663901T3
- Authority
- DK
- Denmark
- Prior art keywords
- formula
- pct
- preparation
- iii
- beta
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C27/00—Processes involving the simultaneous production of more than one class of oxygen-containing compounds
- C07C27/20—Processes involving the simultaneous production of more than one class of oxygen-containing compounds by oxo-reaction
- C07C27/22—Processes involving the simultaneous production of more than one class of oxygen-containing compounds by oxo-reaction with the use of catalysts which are specific for this process
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Epoxy Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9211740A FR2696454B1 (fr) | 1992-10-05 | 1992-10-05 | Procédé de préparation stéréosélective d'un dérivé de la beta-phénylisosérine et son utilisation pour la préparation de dérivés du Taxane. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0663901T3 true DK0663901T3 (da) | 1997-04-14 |
Family
ID=9434118
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK93921981.2T DK0663901T3 (da) | 1992-10-05 | 1993-10-04 | Fremgangsmåde til stereoselektiv fremstilling af et derivat af beta-phenylisoserin samt anvendelse deraf til fremstilling af taxanderivater |
Country Status (23)
| Country | Link |
|---|---|
| US (2) | US5726346A (da) |
| EP (1) | EP0663901B1 (da) |
| JP (1) | JPH08502051A (da) |
| KR (1) | KR100290664B1 (da) |
| AT (1) | ATE150451T1 (da) |
| AU (1) | AU682011B2 (da) |
| CA (1) | CA2146374A1 (da) |
| CZ (1) | CZ283290B6 (da) |
| DE (1) | DE69309086T2 (da) |
| DK (1) | DK0663901T3 (da) |
| ES (1) | ES2099479T3 (da) |
| FI (1) | FI951589A (da) |
| FR (1) | FR2696454B1 (da) |
| GR (1) | GR3022872T3 (da) |
| HU (1) | HUT73171A (da) |
| MX (1) | MX9305765A (da) |
| NZ (1) | NZ256444A (da) |
| PL (2) | PL176503B1 (da) |
| RU (1) | RU2109010C1 (da) |
| SK (1) | SK280576B6 (da) |
| TW (1) | TW436476B (da) |
| WO (1) | WO1994007847A1 (da) |
| ZA (1) | ZA937317B (da) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6025516A (en) * | 1998-10-14 | 2000-02-15 | Chiragene, Inc. | Resolution of 2-hydroxy-3-amino-3-phenylpropionamide and its conversion to C-13 sidechain of taxanes |
| AU775373B2 (en) | 1999-10-01 | 2004-07-29 | Immunogen, Inc. | Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents |
| US7601847B2 (en) | 2004-10-26 | 2009-10-13 | Wyeth | Preparation and purification of 4-(indazol-3-yl)phenols |
| WO2010024762A1 (en) * | 2008-08-26 | 2010-03-04 | Organoclick Aktiebolag | PREPARATION OF β-PHENYL-ISOSERINE DERIVATIVES |
| WO2010062239A1 (en) * | 2008-11-03 | 2010-06-03 | Cordova Armando | A catalytic asymmetric method for the preparation of the paclitaxel (taxol) c-13 side-chain derivatives and its use in the preparation of taxane derivatives |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2629818B1 (fr) * | 1988-04-06 | 1990-11-16 | Centre Nat Rech Scient | Procede de preparation du taxol |
| CA2023645C (fr) * | 1989-08-23 | 2002-03-26 | Jean-Noel Denis | Procede pour la preparation enantioselective de derives de la phenylisoserine |
| FR2662441B1 (fr) * | 1990-05-22 | 1992-10-23 | Rhone Poulenc Sante | Procede de preparation enantioselective de derives de la phenylisoserine. |
| FR2662440B1 (fr) * | 1990-05-22 | 1992-07-31 | Rhone Poulenc Sante | Procede de preparation stereoselective de derives de la phenylisoserine. |
| US5684175A (en) * | 1993-02-05 | 1997-11-04 | Napro Biotherapeutics, Inc. | C-2' hydroxyl-benzyl protected, N-carbamate protected (2R, 3S)- 3-phenylisoserine and production process therefor |
-
1992
- 1992-10-05 FR FR9211740A patent/FR2696454B1/fr not_active Expired - Fee Related
-
1993
- 1993-09-21 MX MX9305765A patent/MX9305765A/es not_active IP Right Cessation
- 1993-10-01 ZA ZA937317A patent/ZA937317B/xx unknown
- 1993-10-02 TW TW082108096A patent/TW436476B/zh not_active IP Right Cessation
- 1993-10-04 HU HU9500966A patent/HUT73171A/hu unknown
- 1993-10-04 NZ NZ256444A patent/NZ256444A/en unknown
- 1993-10-04 CA CA002146374A patent/CA2146374A1/fr not_active Abandoned
- 1993-10-04 PL PL93308240A patent/PL176503B1/pl unknown
- 1993-10-04 RU RU95111377/04A patent/RU2109010C1/ru not_active IP Right Cessation
- 1993-10-04 CZ CZ95840A patent/CZ283290B6/cs not_active IP Right Cessation
- 1993-10-04 ES ES93921981T patent/ES2099479T3/es not_active Expired - Lifetime
- 1993-10-04 EP EP93921981A patent/EP0663901B1/fr not_active Expired - Lifetime
- 1993-10-04 PL PL93319867A patent/PL173791B1/pl unknown
- 1993-10-04 DK DK93921981.2T patent/DK0663901T3/da active
- 1993-10-04 DE DE69309086T patent/DE69309086T2/de not_active Expired - Fee Related
- 1993-10-04 JP JP6508786A patent/JPH08502051A/ja not_active Ceased
- 1993-10-04 AU AU51149/93A patent/AU682011B2/en not_active Ceased
- 1993-10-04 SK SK437-95A patent/SK280576B6/sk unknown
- 1993-10-04 US US08/411,693 patent/US5726346A/en not_active Expired - Fee Related
- 1993-10-04 KR KR1019950701301A patent/KR100290664B1/ko not_active IP Right Cessation
- 1993-10-04 WO PCT/FR1993/000966 patent/WO1994007847A1/fr active IP Right Grant
- 1993-10-04 AT AT93921981T patent/ATE150451T1/de not_active IP Right Cessation
-
1995
- 1995-04-04 FI FI951589A patent/FI951589A/fi unknown
-
1997
- 1997-03-20 GR GR960402773T patent/GR3022872T3/el unknown
- 1997-11-10 US US08/967,795 patent/US6114550A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| GR3022872T3 (en) | 1997-06-30 |
| PL176503B1 (pl) | 1999-06-30 |
| FI951589A0 (fi) | 1995-04-04 |
| FI951589A (fi) | 1995-04-04 |
| HUT73171A (en) | 1996-06-28 |
| US6114550A (en) | 2000-09-05 |
| WO1994007847A1 (fr) | 1994-04-14 |
| ATE150451T1 (de) | 1997-04-15 |
| KR100290664B1 (ko) | 2001-09-17 |
| EP0663901A1 (fr) | 1995-07-26 |
| PL308240A1 (en) | 1995-07-24 |
| MX9305765A (es) | 1994-05-31 |
| US5726346A (en) | 1998-03-10 |
| CA2146374A1 (fr) | 1994-04-14 |
| EP0663901B1 (fr) | 1997-03-19 |
| SK280576B6 (sk) | 2000-04-10 |
| DE69309086T2 (de) | 1997-09-25 |
| RU2109010C1 (ru) | 1998-04-20 |
| FR2696454B1 (fr) | 1994-11-25 |
| SK43795A3 (en) | 1995-09-13 |
| AU682011B2 (en) | 1997-09-18 |
| CZ283290B6 (cs) | 1998-02-18 |
| KR950703499A (ko) | 1995-09-20 |
| ES2099479T3 (es) | 1997-05-16 |
| NZ256444A (en) | 1996-06-25 |
| CZ84095A3 (en) | 1995-09-13 |
| TW436476B (en) | 2001-05-28 |
| ZA937317B (en) | 1994-04-22 |
| AU5114993A (en) | 1994-04-26 |
| DE69309086D1 (de) | 1997-04-24 |
| RU95111377A (ru) | 1996-12-27 |
| HU9500966D0 (en) | 1995-06-28 |
| JPH08502051A (ja) | 1996-03-05 |
| FR2696454A1 (fr) | 1994-04-08 |
| PL173791B1 (pl) | 1998-04-30 |
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